 Cholestasis
"Cholestasis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Impairment of bile flow due to obstruction in small bile ducts (INTRAHEPATIC CHOLESTASIS) or obstruction in large bile ducts (EXTRAHEPATIC CHOLESTASIS).
| Descriptor ID |
D002779
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| MeSH Number(s) |
C06.130.120.135
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| Concept/Terms |
Cholestasis- Cholestasis
- Cholestases
- Biliary Stasis
- Biliary Stases
- Stases, Biliary
- Stasis, Biliary
- Bile Duct Obstruction
- Bile Duct Obstructions
- Duct Obstruction, Bile
- Duct Obstructions, Bile
- Obstruction, Bile Duct
- Obstructions, Bile Duct
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Below are MeSH descriptors whose meaning is more general than "Cholestasis".
Below are MeSH descriptors whose meaning is more specific than "Cholestasis".
This graph shows the total number of publications written about "Cholestasis" by people in this website by year, and whether "Cholestasis" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 1 | 0 | 1 | | 1997 | 1 | 2 | 3 | | 1998 | 3 | 0 | 3 | | 1999 | 1 | 0 | 1 | | 2002 | 0 | 1 | 1 | | 2003 | 3 | 0 | 3 | | 2004 | 3 | 3 | 6 | | 2005 | 1 | 4 | 5 | | 2006 | 4 | 0 | 4 | | 2009 | 1 | 1 | 2 | | 2010 | 4 | 0 | 4 | | 2011 | 5 | 2 | 7 | | 2012 | 1 | 0 | 1 | | 2013 | 3 | 2 | 5 | | 2014 | 1 | 2 | 3 | | 2015 | 4 | 3 | 7 | | 2016 | 3 | 1 | 4 | | 2017 | 2 | 1 | 3 | | 2018 | 3 | 0 | 3 | | 2019 | 4 | 1 | 5 | | 2020 | 4 | 1 | 5 | | 2021 | 11 | 0 | 11 | | 2022 | 9 | 0 | 9 | | 2023 | 11 | 0 | 11 |
To return to the timeline, click here.
Below are the most recent publications written about "Cholestasis" by people in Profiles.
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Teckman J, Rosenthal P, Ignacio RV, Spino C, Bass LM, Horslen S, Wang K, Magee JC, Karpen S, Asai A, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Shneider BL, Sokol RJ. Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance. Hepatol Commun. 2023 12 01; 7(12).
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Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2024 05 01; 79(5):986-1004.
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Boster JM, Goodrich NP, Spino C, Loomes KM, Alonso EM, Kamath BM, Sokol RJ, Karpen S, Miethke A, Shneider BL, Molleston JP, Kohli R, Horslen SP, Rosenthal P, Valentino PL, Teckman JH, Hangartner TN, Sundaram SS. Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease. Hepatol Commun. 2023 11 01; 7(11).
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Mims TS, Kumari R, Leathem C, Antunes K, Joseph S, Yen MI, Ferstl D, Jamieson SM, Sabbar A, Biebel C, Lazarevic N, Willis NB, Henry L, Yen CE, Smith JP, Gosain A, Meisel M, Willis KA, Talati AJ, Elabiad MT, Hibl B, Pierre JF. Altered hepatic and intestinal homeostasis in a neonatal murine model of short-term total parenteral nutrition and antibiotics. Am J Physiol Gastrointest Liver Physiol. 2023 12 01; 325(6):G556-G569.
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Harding E, Cho S, Garrington T, Mandell E. A Neonate Presenting with Cholestasis and Thrombocytopenia. Neoreviews. 2023 09 01; 24(9):e583-e586.
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Shearn CT, Anderson AL, Devereaux MW, El Kasmi KC, Orlicky DJ, Sokol RJ. Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition. PLoS One. 2023; 18(8):e0290385.
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Bowlus CL, Eksteen B, Cheung AC, Thorburn D, Moylan CA, Pockros PJ, Forman LM, Dorenbaum A, Hirschfield GM, Kennedy C, Jaecklin T, McKibben A, Chien E, Baek M, Vig P, Levy C. Safety, tolerability, and efficacy of maralixibat in adults with primary sclerosing cholangitis: Open-label pilot study. Hepatol Commun. 2023 06 01; 7(6).
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 05 12; 13(1):7752.
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Ghosh S, Devereaux MW, Anderson AL, El Kasmi KC, Sokol RJ. Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis. Hepatol Commun. 2023 03 01; 7(3):e0056.
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Trivedi P, Saben JL, Liu L, Malamon JS, Pomfret E, Pshak T. Preliminary safety and efficacy of laser stricturotomy for treatment of refractory biliary anastomotic strictures following liver transplantation. Am J Transplant. 2023 04; 23(4):573-576.
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