Ronald J Sokol
Title | Distinguished Professor |
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Institution | University of Colorado Denver - Anschutz Medical Campus |
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Department | SOM-PEDS |
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Phone | 720/777-3929 |
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ORCID
| 0000-0001-7433-4095 |
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Biography 1971 | Phi Beta Kappa, University of Illinois, Urbana | 1972 | Bronze Tablet, University of Illinois, Urbana | 1976 | Alpha Omega Alpha, University of Chicago Pritzker School of Medicine | 1986 | Basil O'Connor Award, March of Dimes | 1990 | Mead Johnson Award for Nutritional Research, American Institute of Nutrition | 1994 - 2021 | Best Doctors in America | 2002 | America's Top Pediatricians, Consumers’ Research Council of America | 2003 | 2003 Nutrition Award , American Academy of Pediatrics, Committee on Nutrition | 2004 | Hall of Honor, Cincinnati Pediatric Historical Society | 2006 - 2008 | Top Doctors in Denver, 5280 Magazine | 2009 | James E. Strain M.D. Award in Pediatrics, Children’s Hospital Colorado Medical Staff, | 2009 | Pediatric Liver Research Award, , Alpha-1 Kids and the Alpha-One Association | 2009 | Harry Shwachman Award , North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) | 2010 | Arnold Silverman, MD Endowed Chair in Digestive Health, Children’s Hospital Colorado | 2014 - 2020 | Governing Board, American Association for the Study of Liver Diseases | 2011 - 2022 | Top Doctors, U.S. News and World Report | 2015 | Career Teaching Scholar Award, Department of Pediatrics, University of Colorado School of Medicine | 2015 | Fellow of AASLD, American Association for the Study of Liver Diseases | 2018 | President, American Association for the Study of Liver Diseases | 2019 | Peak of Excellence Award, American Liver Foundation, Rocky Mountain Chapter | 2020 | 2020 Sass-Kortsak Award, Canadian Association for the Study of the Liver and Canadian Liver Foundation | 2022 | Distinguished Professor, University of Colorado |
Overview Research UM1TR004399 (SOKOL, RONALD J.)Sep 15, 2023 - Jul 31, 2030 NIH Colorado Clinical and Translational Sciences Institute (CCTSI) Role: Principal Investigator |
| UL1TR002535 (SOKOL, RONALD J.)May 1, 2018 - Apr 30, 2024 NIH Colorado Clinical and Transational Sciences Institute Role: Principal Investigator |
| TL1TR001081 (SOKOL, RONALD J.)Sep 26, 2013 - Jul 31, 2018 NIH Colorado Clinical and Translational Sciences Institute Role: Principal Investigator |
| UL1TR001082 (SOKOL, RONALD J.)Sep 26, 2013 - Jul 31, 2018 NIH Colorado Clinical and Translational Sciences Institute Role: Principal Investigator |
| KL2TR001080 (SOKOL, RONALD J.)Sep 26, 2013 - Apr 30, 2018 NIH Colorado Clinical and Translational Sciences Institute Role: Principal Investigator |
| KL2TR000156 (SOKOL, RONALD J)May 19, 2008 - Oct 31, 2013 NIH Colorado Clinical and Translational Science Institute (KL2) Role: Principal Investigator |
| TL1TR000155 (SOKOL, RONALD J)May 19, 2008 - Oct 31, 2013 NIH Colorado Clinical and Translational Science Institute (TL1) Role: Principal Investigator |
| UL1TR000154 (SOKOL, RONALD J)May 19, 2008 - Oct 31, 2013 NIH Colorado Clinical and Translational Science Institute (UL1) Role: Principal Investigator |
| KL2RR025779 (SOKOL, RONALD J)May 19, 2008 - Apr 30, 2013 NIH Colorado Clinical and Translational Science Institute (KL2) Role: Principal Investigator |
| TL1RR025778 (SOKOL, RONALD J)May 19, 2008 - Apr 30, 2013 NIH Colorado Clinical and Translational Science Institute (TL1) Role: Principal Investigator |
| UL1RR025780 (SOKOL, RONALD J)May 19, 2008 - Apr 30, 2013 NIH Colorado Clinical and Translational Science Institute (UL1) Role: Principal Investigator |
| U54DK078377 (SOKOL, RONALD J)Sep 24, 2004 - Jun 30, 2012 NIH Rare Liver Disease Network Role: Principal Investigator |
| U54RR019455 (SOKOL, RONALD J)Sep 24, 2004 - Jul 31, 2009 NIH Rare Liver Disease Network Role: Principal Investigator |
| T32DK067009 (SOKOL, RONALD J.)Jan 1, 2004 - Jun 30, 2025 NIH Institutional Training Grant in Pediatric Gastroenterology Role: Principal Investigator |
| U01DK062453 (SOKOL, RONALD J.)Sep 15, 2002 - May 31, 2029 NIH Colorado Center of Childhood Liver Disease ResearchNetwork Role: Principal Investigator |
| R01DK038446 (SOKOL, RONALD J)May 10, 1987 - Mar 31, 2006 NIH Oxidant Hepatic Injury in Cholestasis Role: Principal Investigator |
| R29DK038446 (SOKOL, RONALD J)May 10, 1987 - Mar 31, 1992 NIH EFFECT OF VITAMIN E ON HEPATOCYTE STRUCTURE AND FUNCTION Role: Principal Investigator |
Bibliographic
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Kemme S, Sokol RJ, Mack CL. Reply to: "Cytomegalovirus infection in patients with biliary atresia-further questions and possible solutions". Hepatol Commun. 2024 02 01; 8(2). PMID: 38260955.
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Van Hove JLK, Friederich MW, Strode DK, Van Hove RA, Miller KR, Sharma R, Shah H, Estrella J, Gabel L, Horslen S, Kohli R, Lovell MA, Miethke AG, Molleston JP, Romero R, Squires JE, Alonso EM, Guthery SL, Kamath BM, Loomes KM, Rosenthal P, Mysore KR, Cavallo LA, Valentino PL, Magee JC, Sundaram SS, Sokol RJ. Protein biomarkers GDF15 and FGF21 to differentiate mitochondrial hepatopathies from other pediatric liver diseases. Hepatol Commun. 2024 01 01; 8(1). PMID: 38180987.
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Teckman J, Rosenthal P, Ignacio RV, Spino C, Bass LM, Horslen S, Wang K, Magee JC, Karpen S, Asai A, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Shneider BL, Sokol RJ. Neonatal cholestasis in children with Alpha-1-AT deficiency is a risk for earlier severe liver disease with male predominance. Hepatol Commun. 2023 12 01; 7(12). PMID: 38055647.
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Ghosh S, Devereaux MW, Liu C, Sokol RJ. LRH-1 agonist DLPC through STAT6 promotes macrophage polarization and prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2024 05 01; 79(5):986-1004. PMID: 37976384.
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Boster JM, Goodrich NP, Spino C, Loomes KM, Alonso EM, Kamath BM, Sokol RJ, Karpen S, Miethke A, Shneider BL, Molleston JP, Kohli R, Horslen SP, Rosenthal P, Valentino PL, Teckman JH, Hangartner TN, Sundaram SS. Sarcopenia is associated with osteopenia and impaired quality of life in children with genetic intrahepatic cholestatic liver disease. Hepatol Commun. 2023 11 01; 7(11). PMID: 37902507.
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Shearn CT, Anderson AL, Devereaux MW, El Kasmi KC, Orlicky DJ, Sokol RJ. Expression of circadian regulatory genes is dysregulated by increased cytokine production in mice subjected to concomitant intestinal injury and parenteral nutrition. PLoS One. 2023; 18(8):e0290385. PMID: 37647292.
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Publisher Correction: Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 Jul 19; 13(1):11673. PMID: 37468479.
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Kemme S, Canniff JD, Feldman AG, Garth KM, Li S, Pan Z, Sokol RJ, Weinberg A, Mack CL. Cytomegalovirus in biliary atresia is associated with increased pretransplant death, but not decreased native liver survival. Hepatol Commun. 2023 08 01; 7(8). PMID: 37471052.
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Sokol RJ, Gonzales EM, Kamath BM, Baker A, Vig P, Mogul DB, Garner W, Hansen BE, Jacquemin E, Thompson RJ. Predictors of 6-year event-free survival in Alagille syndrome patients treated with maralixibat, an ileal bile acid transporter inhibitor. Hepatology. 2023 12 01; 78(6):1698-1710. PMID: 37278241.
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Squires JE, Miethke AG, Valencia CA, Hawthorne K, Henn L, Van Hove JLK, Squires RH, Bove K, Horslen S, Kohli R, Molleston JP, Romero R, Alonso EM, Bezerra JA, Guthery SL, Hsu E, Karpen SJ, Loomes KM, Ng VL, Rosenthal P, Mysore K, Wang KS, Friederich MW, Magee JC, Sokol RJ. Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children. Hepatol Commun. 2023 06 01; 7(6). PMID: 37184518.
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Ghosh S, Devereaux MW, Orlicky DJ, Sokol RJ. Pharmacologic inhibition of HNF4a prevents parenteral nutrition associated cholestasis in mice. Sci Rep. 2023 05 12; 13(1):7752. PMID: 37173326.
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Thompson RJ, Artan R, Baumann U, Calvo PL, Czubkowski P, Dalgic B, D'Antiga L, Di Giorgio A, Durmaz ?, Gonzal?s E, Grammatikopoulos T, Gupte G, Hardikar W, Houwen RHJ, Kamath BM, Karpen SJ, Lacaille F, Lachaux A, Lainka E, Loomes KM, Mack CL, Mattsson JP, McKiernan P, Ni Q, ?zen H, Rajwal SR, Roquelaure B, Shteyer E, Sokal E, Sokol RJ, Soufi N, Sturm E, Tessier ME, van der Woerd WL, Verkade HJ, Vittorio JM, Wallefors T, Warholic N, Yu Q, Horn P, Kjems L. Interim results from an ongoing, open-label, single-arm trial of odevixibat in progressive familial intrahepatic cholestasis. JHEP Rep. 2023 Aug; 5(8):100782. PMID: 37456676.
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Ghosh S, Devereaux MW, Anderson AL, El Kasmi KC, Sokol RJ. Stat3 role in the protective effect of FXR Agonist in parenteral nutrition-associated cholestasis. Hepatol Commun. 2023 03 01; 7(3):e0056. PMID: 36848082.
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Harpavat S, Hawthorne K, Setchell KDR, Rivas MN, Henn L, Beil CA, Karpen SJ, Ng VL, Alonso EM, Bezerra JA, Guthery SL, Horslen S, Loomes KM, McKiernan P, Magee JC, Merion RM, Molleston JP, Rosenthal P, Thompson RJ, Wang KS, Sokol RJ, Shneider BL. Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy. Hepatology. 2023 03 01; 77(3):862-873. PMID: 36131538.
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Shearn CT, Anderson AL, Miller CG, Noyd RC, Devereaux MW, Balasubramaniyan N, Orlicky DJ, Schmidt EE, Sokol RJ. Thioredoxin reductase 1 regulates hepatic inflammation and macrophage activation during acute cholestatic liver injury. Hepatol Commun. 2023 01 01; 7(1):e0020. PMID: 36633484.
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Felzen A, van Wessel DBE, Gonzales E, Thompson RJ, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher JBF, Serranti D, Arikan C, Polat E, Debray D, Lacaille F, Goncalves C, Hierro L, Mu?oz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsofi A, Calvo PL, Grabhorn E, Hartleif S, van der Woerd WJ, Kamath BM, Wang JS, Li L, Durmaz ?, Kerkar N, J?rgensen MH, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Ferreira CT, Guerrero FO, Wang H, Sency V, Kim KM, Chen HL, de Carvalho E, Fabre A, Bernabeu JQ, Zellos A, Alonso EM, Sokol RJ, Suchy FJ, Loomes KM, McKiernan PJ, Rosenthal P, Turmelle Y, Horslen S, Schwarz K, Bezerra JA, Wang K, Hansen BE, Verkade HJ. Genotype-phenotype relationships of truncating mutations, p.E297G and p.D482G in bile salt export pump deficiency. JHEP Rep. 2023 Feb; 5(2):100626. PMID: 36687469.
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Shearn CT, Anderson AL, Devereux MW, Orlicky DJ, Michel C, Petersen DR, Miller CG, Harpavat S, Schmidt EE, Sokol RJ. The autophagic protein p62 is a target of reactive aldehydes in human and murine cholestatic liver disease. PLoS One. 2022; 17(11):e0276879. PMID: 36378690.
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Leung DH, Devaraj S, Goodrich NP, Chen X, Rajapakshe D, Ye W, Andreev V, Minard CG, Guffey D, Molleston JP, Bass LM, Karpen SJ, Kamath BM, Wang KS, Sundaram SS, Rosenthal P, McKiernan P, Loomes KM, Jensen MK, Horslen SP, Bezerra JA, Magee JC, Merion RM, Sokol RJ, Shneider BL, Alonso E, Bass L, Kelly S, Riordan M, Melin-Aldana H, Bezerra J, Bove K, Heubi J, Miethke A, Tiao G, Denlinger J, Chapman E, Sokol R, Feldman A, Mack C, Narkewicz M, Suchy F, Sundaram SS, Van Hove J, Garcia B, Kauma M, Kocher K, Steinbeiss M, Lovell M, Loomes KM, Piccoli D, Rand E, Russo P, Spinner N, Erlichman J, Stalford S, Pakstis D, King S, Squires R, Sindhi R, Venkat V, Bukauskas K, McKiernan P, Haberstroh L, Squires J, Rosenthal P, Bull L, Curry J, Langlois C, Kim G, Teckman J, Kociela V, Nagy R, Patel S, Cerkoski J, Molleston JP, Bozic M, Subbarao G, Klipsch A, Sawyers C, Cummings O, Horslen SP, Murray K, Hsu E, Cooper K, Young M, Finn L, Kamath BM, Ng V, Quammie C, Putra J, Sharma D, Parmar A, Guthery S, Jensen K, Rutherford A, Lowichik A, Book L, Meyers R, Hall T, Wang KS, Michail S, Thomas D, Goodhue C, Kohli R, Wang L, Soufi N, Thomas D, Karpen S, Gupta N, Romero R, Vos MB, Tory R, Berauer JP, Abramowsky C, McFall J, Shneider BL, Harpavat S, Hertel P, Leung D, Tessier M, Schady D, Cavallo L, Olvera D, Banks C, Tsai C, Thompson R, Doo E, Hoofnagle J, Sherker A, Torrance R, Hall S, Magee J, Merion R, Spino C, Ye W. Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. Hepatology. 2023 02 01; 77(2):530-545. PMID: 36069569.
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Wynia MK, Beaty LE, Bennett TD, Carlson NE, Davis CB, Kwan BM, Mayer DA, Ong TC, Russell S, Steele JD, Stocker HR, Wogu AF, Zane RD, Sokol RJ, Ginde AA. Real-World Evidence of Neutralizing Monoclonal Antibodies for Preventing Hospitalization and Mortality in COVID-19 Outpatients. Chest. 2023 05; 163(5):1061-1070. PMID: 36441040.
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Chaidez A, Pan Z, Sundaram SS, Boster J, Lovell M, Sokol RJ, Mack CL. The discriminatory ability of FibroScan liver stiffness measurement, controlled attenuation parameter, and FibroScan-aspartate aminotransferase to predict severity of liver disease in children. Hepatol Commun. 2022 11; 6(11):3015-3023. PMID: 36069338.
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Porto A, Pan Z, Zhou W, Sokol RJ, Klaczkiewicz K, Sundaram SS. Macronutrient and Micronutrient Intake in Adolescents With Non-alcoholic Fatty Liver Disease: The Association With Disease Severity. J Pediatr Gastroenterol Nutr. 2022 11 01; 75(5):666-674. PMID: 35897136.
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Kamath BM, Alonso EM, Heubi JE, Karpen SJ, Sundaram SS, Shneider BL, Sokol RJ. Fat Soluble Vitamin Assessment and Supplementation in Cholestasis. Clin Liver Dis. 2022 08; 26(3):537-553. PMID: 35868689.
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Shneider BL, Spino CA, Kamath BM, Magee JC, Ignacio RV, Huang S, Horslen SP, Molleston JP, Miethke AG, Kohli R, Leung DH, Jensen MK, Loomes KM, Karpen SJ, Mack C, Rosenthal P, Squires RH, Baker A, Rajwal S, Kelly D, Sokol RJ, Thompson RJ. Impact of long-term administration of maralixibat on children with cholestasis secondary to Alagille syndrome. Hepatol Commun. 2022 08; 6(8):1922-1933. PMID: 35672955.
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Shneider BL, Kamath BM, Magee JC, Goodrich NP, Loomes KM, Ye W, Spino C, Alonso EM, Molleston JP, Bezerra JA, Wang KS, Karpen SJ, Horslen SP, Guthery SL, Rosenthal P, Squires RH, Sokol RJ. Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases-Examination of cholestatic liver disease in Alagille syndrome. Hepatol Commun. 2022 08; 6(8):1910-1921. PMID: 35506349.
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Bass LM, Ye W, Hawthorne K, Leung DH, Murray KF, Molleston JP, Romero R, Karpen S, Rosenthal P, Loomes KM, Wang KS, Squires RH, Miethke A, Ng VL, Horslen S, Kyle Jensen M, Sokol RJ, Magee JC, Shneider BL. Risk of variceal hemorrhage and pretransplant mortality in children with biliary atresia. Hepatology. 2022 09; 76(3):712-726. PMID: 35271743.
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Fischler B, Czubkowski P, Dezsofi A, Liliemark U, Socha P, Sokol RJ, Svensson JF, Davenport M. Incidence, Impact and Treatment of Ongoing CMV Infection in Patients with Biliary Atresia in Four European Centres. J Clin Med. 2022 Feb 11; 11(4). PMID: 35207217.
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Wynia MK, Beaty LE, Bennett TD, Carlson NE, Davis CB, Kwan BM, Mayer DA, Ong TC, Russell S, Steele J, Stocker HR, Wogu AF, Zane RD, Sokol RJ, Ginde AA. Real World Evidence of Neutralizing Monoclonal Antibodies for Preventing Hospitalization and Mortality in COVID-19 Outpatients. medRxiv. 2022 Jan 11. PMID: 35043117.
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Leung DH, Sorensen LG, Ye W, Hawthorne K, Ng VL, Loomes KM, Fredericks EM, Alonso EM, Heubi JE, Horslen SP, Karpen SJ, Molleston JP, Rosenthal P, Sokol RJ, Squires RH, Wang KS, Kamath BM, Magee JC. Neurodevelopmental Outcomes in Children With Inherited Liver Disease and Native Liver. J Pediatr Gastroenterol Nutr. 2022 01 01; 74(1):96-103. PMID: 34694263.
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El Kasmi KC, Ghosh S, Anderson AL, Devereaux MW, Balasubramaniyan N, D'Alessandro A, Orlicky DJ, Suchy FJ, Shearn CT, Sokol RJ. Pharmacologic activation of hepatic farnesoid X receptor prevents parenteral nutrition-associated cholestasis in mice. Hepatology. 2022 02; 75(2):252-265. PMID: 34387888.
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Feldman AG, Sokol RJ. Neonatal Cholestasis: Updates on Diagnostics, Therapeutics, and Prevention. Neoreviews. 2021 12 01; 22(12):e819-e836. PMID: 34850148.
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El Kasmi KC, Anderson AL, Devereaux MW, Balasubramaniyan N, Suchy FJ, Orlicky DJ, Shearn CT, Sokol RJ. Interrupting tumor necrosis factor-alpha signaling prevents parenteral nutrition-associated cholestasis in mice. JPEN J Parenter Enteral Nutr. 2022 07; 46(5):1096-1106. PMID: 34664730.
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Balasubramaniyan N, Devereaux MW, Orlicky DJ, Sokol RJ, Suchy FJ. miR-199a-5p inhibits the expression of ABCB11 in obstructive cholestasis. J Biol Chem. 2021 12; 297(6):101400. PMID: 34774795.
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Boster JM, Feldman AG, Mack CL, Sokol RJ, Sundaram SS. Malnutrition in Biliary Atresia: Assessment, Management, and Outcomes. Liver Transpl. 2022 03; 28(3):483-492. PMID: 34669243.
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Hertel PM, Hawthorne K, Kim S, Finegold MJ, Shneider BL, Squires JE, Gupta NA, Bull LN, Murray KF, Kerkar N, Ng VL, Molleston JP, Bezerra JA, Loomes KM, Taylor SA, Schwarz KB, Turmelle YP, Rosenthal P, Magee JC, Sokol RJ. Presentation and Outcomes of Infants With Idiopathic Cholestasis: A Multicenter Prospective Study. J Pediatr Gastroenterol Nutr. 2021 10 01; 73(4):478-484. PMID: 34310436.
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Ghosh S, Devereaux MW, Anderson AL, Gehrke S, Reisz JA, D'Alessandro A, Orlicky DJ, Lovell M, El Kasmi KC, Shearn CT, Sokol RJ. NF-?B Regulation of LRH-1 and ABCG5/8 Potentiates Phytosterol Role in the Pathogenesis of Parenteral Nutrition-Associated Cholestasis. Hepatology. 2021 12; 74(6):3284-3300. PMID: 34310734.
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Hertel PM, Bull LN, Thompson RJ, Goodrich NP, Ye W, Magee JC, Squires RH, Bass LM, Heubi JE, Kim GE, Ranganathan S, Schwarz KB, Bozic MA, Horslen SP, Clifton MS, Turmelle YP, Suchy FJ, Superina RA, Wang KS, Loomes KM, Kamath BM, Sokol RJ, Shneider BL. Mutation Analysis and Disease Features at Presentation in a Multi-Center Cohort of Children With Monogenic Cholestasis. J Pediatr Gastroenterol Nutr. 2021 08 01; 73(2):169-177. PMID: 34016879.
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van Wessel DBE, Thompson RJ, Gonzales E, Jankowska I, Shneider BL, Sokal E, Grammatikopoulos T, Kadaristiana A, Jacquemin E, Spraul A, Lipinski P, Czubkowski P, Rock N, Shagrani M, Broering D, Algoufi T, Mazhar N, Nicastro E, Kelly D, Nebbia G, Arnell H, Fischler B, Hulscher JBF, Serranti D, Arikan C, Debray D, Lacaille F, Goncalves C, Hierro L, Mu?oz Bartolo G, Mozer-Glassberg Y, Azaz A, Brecelj J, Dezsofi A, Luigi Calvo P, Krebs-Schmitt D, Hartleif S, van der Woerd WL, Wang JS, Li LT, Durmaz ?, Kerkar N, H?rby J?rgensen M, Fischer R, Jimenez-Rivera C, Alam S, Cananzi M, Laverdure N, Targa Ferreira C, Ordonez F, Wang H, Sency V, Mo Kim K, Chen HL, Carvalho E, Fabre A, Quintero Bernabeu J, Alonso EM, Sokol RJ, Suchy FJ, Loomes KM, McKiernan PJ, Rosenthal P, Turmelle Y, Rao GS, Horslen S, Kamath BM, Rogalidou M, Karnsakul WW, Hansen B, Verkade HJ. Impact of Genotype, Serum Bile Acids, and Surgical Biliary Diversion on Native Liver Survival in FIC1 Deficiency. Hepatology. 2021 08; 74(2):892-906. PMID: 33666275.
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Benam CH, Baler G, Duke R, McNeal DM, Muller KA, Bodine C, Morrato EH, Sokol RJ. Fostering innovation at Academic Medical Centers: The Case of University of Colorado Anschutz Medical Campus. J Clin Transl Sci. 2021; 5(1):e148. PMID: 34527288.
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Karpen SJ, Kamath BM, Alexander JJ, Ichetovkin I, Rosenthal P, Sokol RJ, Dunn S, Thompson RJ, Heubi JE. Use of a Comprehensive 66-Gene Cholestasis Sequencing Panel in 2171 Cholestatic Infants, Children, and Young Adults. J Pediatr Gastroenterol Nutr. 2021 05 01; 72(5):654-660. PMID: 33720099.
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Venkat V, Ng VL, Magee JC, Ye W, Hawthorne K, Harpavat S, Molleston JP, Murray KF, Wang KS, Soufi N, Bass LM, Alonso EM, Bezerra JA, Jensen MK, Kamath BM, Loomes KM, Mack CL, Rosenthal P, Shneider BL, Squires RH, Sokol RJ, Karpen SJ. Modeling Outcomes in Children With Biliary Atresia With Native Liver After 2 Years of Age. Hepatol Commun. 2020 Dec; 4(12):1824-1834. PMID: 33305153.
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Shneider BL, Goodrich NP, Ye W, Sawyers C, Molleston JP, Merion RM, Leung DH, Karpen SJ, Kamath BM, Cavallo L, Wang K, Teckman JH, Squires JE, Sundaram SS, Rosenthal P, Romero R, Murray KF, Loomes KM, Jensen MK, Bezerra JA, Bass LM, Sokol RJ, Magee JC. Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease. Hepatol Commun. 2020 Nov; 4(11):1694-1707. PMID: 33163838.
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Feldman AG, Sokol RJ. Recent developments in diagnostics and treatment of neonatal cholestasis. Semin Pediatr Surg. 2020 Aug; 29(4):150945. PMID: 32861449.
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Teckman J, Rosenthal P, Hawthorne K, Spino C, Bass LM, Murray KF, Kerkar N, Magee JC, Karpen S, Heubi JE, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Sherker AH, Sokol RJ. Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension. J Pediatr. 2020 12; 227:81-86.e4. PMID: 32663593.
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Kamath BM, Spino C, McLain R, Magee JC, Fredericks EM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Alonso EM, Murray KF, Loomes KM, Kyle Jensen M, Karpen SJ, Rosenthal P, Thomas D, Sokol RJ, Shneider BL. Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With Alagille Syndrome. Hepatol Commun. 2020 Jul; 4(7):1012-1018. PMID: 32626833.
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Cooper DM, Guay-Woodford L, Blazar BR, Bowman S, Byington CL, Dome J, Forthal D, Konstan MW, Kuppermann N, Liem RI, Ochoa ER, Pollock BH, Price OA, Ramsey BW, Ross LF, Sokol RJ, Wright RJ. Reopening Schools Safely: The Case for Collaboration, Constructive Disruption of Pre-Coronavirus 2019 Expectations, and Creative Solutions. J Pediatr. 2020 08; 223:183-185. PMID: 32445649.
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Lee WS, Chew KS, Ng RT, Kasmi KE, Sokol RJ. Intestinal failure-associated liver disease (IFALD): insights into pathogenesis and advances in management. Hepatol Int. 2020 May; 14(3):305-316. PMID: 32356227.
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Jestin M, Kapnick SM, Tarasenko TN, Burke CT, Zerfas PM, Diaz F, Vernon H, Singh LN, Sokol RJ, McGuire PJ. Mitochondrial disease disrupts hepatic allostasis and lowers the threshold for immune-mediated liver toxicity. Mol Metab. 2020 07; 37:100981. PMID: 32283081.
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Khalaf RT, Sokol RJ. New Insights Into Intestinal Failure-Associated Liver Disease in Children. Hepatology. 2020 04; 71(4):1486-1498. PMID: 32003009.
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Kamath BM, Ye W, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman J, Wang KS, Thompson R, Magee JC, Sokol RJ. Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study. Hepatol Commun. 2020 Mar; 4(3):387-398. PMID: 33313463.
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Squires JE, Ng VL, Hawthorne K, Henn LL, Sorensen LG, Fredericks EM, Alonso EM, Murray KF, Loomes KM, Karpen SJ, Cavallo LA, Molleston JP, Bezerra JA, Rosenthal P, Squires RH, Wang KS, Schwarz KB, Arnon R, Magee JC, Sokol RJ. Neurodevelopmental Outcomes in Preschool and School Aged Children With Biliary Atresia and Their Native Liver. J Pediatr Gastroenterol Nutr. 2020 01; 70(1):79-86. PMID: 31503218.
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Balasubramaniyan N, Devereaux MW, Orlicky DJ, Sokol RJ, Suchy FJ. Up-regulation of miR-let7a-5p Leads to Decreased Expression of ABCC2 in Obstructive Cholestasis. Hepatol Commun. 2019 Dec; 3(12):1674-1686. PMID: 31832574.
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Feldman AG, Sokol RJ. Neonatal cholestasis: emerging molecular diagnostics and potential novel therapeutics. Nat Rev Gastroenterol Hepatol. 2019 06; 16(6):346-360. PMID: 30903105.
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Sundaram SS, Swiderska-Syn M, Sokol RJ, Halbower AC, Capocelli KE, Pan Z, Robbins K, Graham B, Diehl AM. Nocturnal Hypoxia Activation of the Hedgehog Signaling Pathway Affects Pediatric Nonalcoholic Fatty Liver Disease Severity. Hepatol Commun. 2019 Jul; 3(7):883-893. PMID: 31334441.
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Mack CL, Spino C, Alonso EM, Bezerra JA, Moore J, Goodhue C, Ng VL, Karpen SJ, Venkat V, Loomes KM, Wang K, Sherker AH, Magee JC, Sokol RJ. A Phase I/IIa Trial of Intravenous Immunoglobulin Following Portoenterostomy in Biliary Atresia. J Pediatr Gastroenterol Nutr. 2019 04; 68(4):495-501. PMID: 30664564.
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Kim S, Moore J, Alonso E, Bednarek J, Bezerra JA, Goodhue C, Karpen SJ, Loomes KM, Magee JC, Ng VL, Sherker AH, Smith C, Spino C, Venkat V, Wang K, Sokol RJ, Mack CL. Correlation of Immune Markers With Outcomes in Biliary Atresia Following Intravenous Immunoglobulin Therapy. Hepatol Commun. 2019 May; 3(5):685-696. PMID: 31061956.
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Berauer JP, Mezina AI, Okou DT, Sabo A, Muzny DM, Gibbs RA, Hegde MR, Chopra P, Cutler DJ, Perlmutter DH, Bull LN, Thompson RJ, Loomes KM, Spinner NB, Rajagopalan R, Guthery SL, Moore B, Yandell M, Harpavat S, Magee JC, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Alonso EM, Rosenthal P, Squires RH, Wang KS, Finegold MJ, Russo P, Sherker AH, Sokol RJ, Karpen SJ. Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome. Hepatology. 2019 09; 70(3):899-910. PMID: 30664273.
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Loomes KM, Spino C, Goodrich NP, Hangartner TN, Marker AE, Heubi JE, Kamath BM, Shneider BL, Rosenthal P, Hertel PM, Karpen SJ, Molleston JP, Murray KF, Schwarz KB, Squires RH, Teckman J, Turmelle YP, Alonso EM, Sherker AH, Magee JC, Sokol RJ. Bone Density in Children With Chronic Liver Disease Correlates With Growth and Cholestasis. Hepatology. 2019 01; 69(1):245-257. PMID: 30063078.
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Shneider BL, Spino C, Kamath BM, Magee JC, Bass LM, Setchell KD, Miethke A, Molleston JP, Mack CL, Squires RH, Murray KF, Loomes KM, Rosenthal P, Karpen SJ, Leung DH, Guthery SL, Thomas D, Sherker AH, Sokol RJ. Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome. Hepatol Commun. 2018 Oct; 2(10):1184-1198. PMID: 30288474.
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Alonso EM, Ye W, Hawthorne K, Venkat V, Loomes KM, Mack CL, Hertel PM, Karpen SJ, Kerkar N, Molleston JP, Murray KF, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Suchy FJ, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Bezerra JA, Magee JC. Impact of Steroid Therapy on Early Growth in Infants with Biliary Atresia: The Multicenter Steroids in Biliary Atresia Randomized Trial. J Pediatr. 2018 11; 202:179-185.e4. PMID: 30244988.
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Bezerra JA, Wells RG, Mack CL, Karpen SJ, Hoofnagle JH, Doo E, Sokol RJ. Biliary Atresia: Clinical and Research Challenges for the Twenty-First Century. Hepatology. 2018 09; 68(3):1163-1173. PMID: 29604222.
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Larson AA, Baker PR, Milev MP, Press CA, Sokol RJ, Cox MO, Lekostaj JK, Stence AA, Bossler AD, Mueller JM, Prematilake K, Tadjo TF, Williams CA, Sacher M, Moore SA. TRAPPC11 and GOSR2 mutations associate with hypoglycosylation of a-dystroglycan and muscular dystrophy. Skelet Muscle. 2018 05 31; 8(1):17. PMID: 29855340.
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Sundaram SS, Halbower AC, Klawitter J, Pan Z, Robbins K, Capocelli KE, Sokol RJ. Treating Obstructive Sleep Apnea and Chronic Intermittent Hypoxia Improves the Severity of Nonalcoholic Fatty Liver Disease in Children. J Pediatr. 2018 07; 198:67-75.e1. PMID: 29752170.
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El Kasmi KC, Vue PM, Anderson AL, Devereaux MW, Ghosh S, Balasubramaniyan N, Fillon SA, Dahrenmoeller C, Allawzi A, Woods C, McKenna S, Wright CJ, Johnson L, D'Alessandro A, Reisz JA, Nozik-Grayck E, Suchy FJ, Sokol RJ. Macrophage-derived IL-1?/NF-?B signaling mediates parenteral nutrition-associated cholestasis. Nat Commun. 2018 04 11; 9(1):1393. PMID: 29643332.
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Ng VL, Sorensen LG, Alonso EM, Fredericks EM, Ye W, Moore J, Karpen SJ, Shneider BL, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Rosenthal P, Squires RH, Wang K, Arnon R, Schwarz KB, Turmelle YP, Haber BH, Sherker AH, Magee JC, Sokol RJ. Neurodevelopmental Outcome of Young Children with Biliary Atresia and Native Liver: Results from the ChiLDReN Study. J Pediatr. 2018 05; 196:139-147.e3. PMID: 29519540.
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Lee WS, Wong SY, Ivy DD, Sokol RJ. Hepatopulmonary Syndrome and Portopulmonary Hypertension in Children: Recent Advances in Diagnosis and Management. J Pediatr. 2018 05; 196:14-21.e1. PMID: 29514741.
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Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Whitington PF, Rosenthal P, Squires RH, Guthery SL, Arnon R, Schwarz KB, Turmelle YP, Sherker AH, Sokol RJ. Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia? PLoS One. 2017; 12(5):e0176275. PMID: 28493866.
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Wang KS, Tiao G, Bass LM, Hertel PM, Mogul D, Kerkar N, Clifton M, Azen C, Bull L, Rosenthal P, Stewart D, Superina R, Arnon R, Bozic M, Brandt ML, Dillon PA, Fecteau A, Iyer K, Kamath B, Karpen S, Karrer F, Loomes KM, Mack C, Mattei P, Miethke A, Soltys K, Turmelle YP, West K, Zagory J, Goodhue C, Shneider BL. Analysis of surgical interruption of the enterohepatic circulation as a treatment for pediatric cholestasis. Hepatology. 2017 05; 65(5):1645-1654. PMID: 28027587.
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Feldman AG, Sokol RJ, Hardison RM, Alonso EM, Squires RH, Narkewicz MR. Lactate and Lactate: Pyruvate Ratio in the Diagnosis and Outcomes of Pediatric Acute Liver Failure. J Pediatr. 2017 03; 182:217-222.e3. PMID: 28088395.
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Sundaram SS, Mack CL, Feldman AG, Sokol RJ. Biliary atresia: Indications and timing of liver transplantation and optimization of pretransplant care. Liver Transpl. 2017 01; 23(1):96-109. PMID: 27650268.
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Sokol RJ. A New Old Treatment for Vitamin E Deficiency in Cholestasis. J Pediatr Gastroenterol Nutr. 2016 12; 63(6):577-578. PMID: 27429361.
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Sokol RJ. Newborn Screening for Biliary Atresia: Bilirubin or Bust? J Pediatr Gastroenterol Nutr. 2016 09; 63(3):312-3. PMID: 27101537.
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Woodruff SA, Sontag MK, Accurso FJ, Sokol RJ, Narkewicz MR. Prevalence of elevated liver enzymes in children with cystic fibrosis diagnosed by newborn screen. J Cyst Fibros. 2017 01; 16(1):139-145. PMID: 27555301.
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Sundaram SS, Halbower A, Pan Z, Robbins K, Capocelli KE, Klawitter J, Shearn CT, Sokol RJ. Nocturnal hypoxia-induced oxidative stress promotes progression of pediatric non-alcoholic fatty liver disease. J Hepatol. 2016 09; 65(3):560-9. PMID: 27501738.
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Krowka MJ, Fallon MB, Kawut SM, Fuhrmann V, Heimbach JK, Ramsay MA, Sitbon O, Sokol RJ. International Liver Transplant Society Practice Guidelines: Diagnosis and Management of Hepatopulmonary Syndrome and Portopulmonary Hypertension. Transplantation. 2016 Jul; 100(7):1440-52. PMID: 27326810.
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Verkade HJ, Bezerra JA, Davenport M, Schreiber RA, Mieli-Vergani G, Hulscher JB, Sokol RJ, Kelly DA, Ure B, Whitington PF, Samyn M, Petersen C. Biliary atresia and other cholestatic childhood diseases: Advances and future challenges. J Hepatol. 2016 09; 65(3):631-42. PMID: 27164551.
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Sokol RJ. Molecular Chaperones as Therapy for PFIC: Not So Fast! J Pediatr Gastroenterol Nutr. 2016 Mar; 62(3):360-2. PMID: 26771769.
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Shneider BL, Magee JC, Karpen SJ, Rand EB, Narkewicz MR, Bass LM, Schwarz K, Whitington PF, Bezerra JA, Kerkar N, Haber B, Rosenthal P, Turmelle YP, Molleston JP, Murray KF, Ng VL, Wang KS, Romero R, Squires RH, Arnon R, Sherker AH, Moore J, Ye W, Sokol RJ. Total Serum Bilirubin within 3 Months of Hepatoportoenterostomy Predicts Short-Term Outcomes in Biliary Atresia. J Pediatr. 2016 Mar; 170:211-7.e1-2. PMID: 26725209.
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Wang KS. Newborn Screening for Biliary Atresia. Pediatrics. 2015 Dec; 136(6):e1663-9. PMID: 26620065.
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Sokol RJ. Portopulmonary Hypertension: Opportunities for Precision Pediatrics. J Pediatr Gastroenterol Nutr. 2015 Sep; 61(3):268-9. PMID: 26111300.
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Mouzaki M, Bass LM, Sokol RJ, Piccoli DA, Quammie C, Loomes KM, Heubi JE, Hertel PM, Scheenstra R, Furuya K, Kutsch E, Spinner NB, Robbins KN, Venkat V, Rosenthal P, Beyene J, Baker A, Kamath BM. Early life predictive markers of liver disease outcome in an International, Multicentre Cohort of children with Alagille syndrome. Liver Int. 2016 05; 36(5):755-60. PMID: 26201540.
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Leung DH, Ye W, Molleston JP, Weymann A, Ling S, Paranjape SM, Romero R, Schwarzenberg SJ, Palermo J, Alonso EM, Murray KF, Marshall BC, Sherker AH, Siegel MJ, Krishnamurthy R, Harned R, Karmazyn B, Magee JC, Narkewicz MR. Baseline Ultrasound and Clinical Correlates in Children with Cystic Fibrosis. J Pediatr. 2015 Oct; 167(4):862-868.e2. PMID: 26254836.
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Teckman JH, Rosenthal P, Abel R, Bass LM, Michail S, Murray KF, Rudnick DA, Thomas DW, Spino C, Arnon R, Hertel PM, Heubi J, Kamath BM, Karnsakul W, Loomes KM, Magee JC, Molleston JP, Romero R, Shneider BL, Sherker AH, Sokol RJ. Baseline Analysis of a Young a-1-Antitrypsin Deficiency Liver Disease Cohort Reveals Frequent Portal Hypertension. J Pediatr Gastroenterol Nutr. 2015 Jul; 61(1):94-101. PMID: 25651489.
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Lee WS, Sokol RJ. Intestinal Microbiota, Lipids, and the Pathogenesis of Intestinal Failure-Associated Liver Disease. J Pediatr. 2015 Sep; 167(3):519-26. PMID: 26130113.
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Kamath BM, Chen Z, Romero R, Fredericks EM, Alonso EM, Arnon R, Heubi J, Hertel PM, Karpen SJ, Loomes KM, Murray KF, Rosenthal P, Schwarz KB, Subbarao G, Teckman JH, Turmelle YP, Wang KS, Sherker AH, Sokol RJ, Magee JC. Quality of Life and Its Determinants in a Multicenter Cohort of Children with Alagille Syndrome. J Pediatr. 2015 Aug; 167(2):390-6.e3. PMID: 26059338.
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Feldman AG, Sokol RJ. Noncirrhotic portal hypertension in the pediatric population. Clin Liver Dis (Hoboken). 2015 May; 5(5):116-119. PMID: 31040964.
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Flass T, Tong S, Frank DN, Wagner BD, Robertson CE, Kotter CV, Sokol RJ, Zemanick E, Accurso F, Hoffenberg EJ, Narkewicz MR. Intestinal lesions are associated with altered intestinal microbiome and are more frequent in children and young adults with cystic fibrosis and cirrhosis. PLoS One. 2015; 10(2):e0116967. PMID: 25658710.
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Venkat VL, Shneider BL, Magee JC, Turmelle Y, Arnon R, Bezerra JA, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston J, Murray KF, Ng VL, Raghunathan T, Rosenthal P, Schwartz K, Sherker AH, Sokol RJ, Teckman J, Wang K, Whitington PF, Heubi JE. Total serum bilirubin predicts fat-soluble vitamin deficiency better than serum bile acids in infants with biliary atresia. J Pediatr Gastroenterol Nutr. 2014 Dec; 59(6):702-7. PMID: 25419594.
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Harris JK, El Kasmi KC, Anderson AL, Devereaux MW, Fillon SA, Robertson CE, Wagner BD, Stevens MJ, Pace NR, Sokol RJ. Specific microbiome changes in a mouse model of parenteral nutrition associated liver injury and intestinal inflammation. PLoS One. 2014; 9(10):e110396. PMID: 25329595.
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Ng VL, Haber BH, Magee JC, Miethke A, Murray KF, Michail S, Karpen SJ, Kerkar N, Molleston JP, Romero R, Rosenthal P, Schwarz KB, Shneider BL, Turmelle YP, Alonso EM, Sherker AH, Sokol RJ. Medical status of 219 children with biliary atresia surviving long-term with their native livers: results from a North American multicenter consortium. J Pediatr. 2014 Sep; 165(3):539-546.e2. PMID: 25015575.
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Sullivan JS, Le MT, Pan Z, Rivard C, Love-Osborne K, Robbins K, Johnson RJ, Sokol RJ, Sundaram SS. Oral fructose absorption in obese children with non-alcoholic fatty liver disease. Pediatr Obes. 2015 Jun; 10(3):188-95. PMID: 24961681.
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El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR. Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension. J Immunol. 2014 Jul 15; 193(2):597-609. PMID: 24928992.
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Bezerra JA, Spino C, Magee JC, Shneider BL, Rosenthal P, Wang KS, Erlichman J, Haber B, Hertel PM, Karpen SJ, Kerkar N, Loomes KM, Molleston JP, Murray KF, Romero R, Schwarz KB, Shepherd R, Suchy FJ, Turmelle YP, Whitington PF, Moore J, Sherker AH, Robuck PR, Sokol RJ. Use of corticosteroids after hepatoportoenterostomy for bile drainage in infants with biliary atresia: the START randomized clinical trial. JAMA. 2014 May 07; 311(17):1750-9. PMID: 24794368.
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Fenner EK, Boguniewicz J, Tucker RM, Sokol RJ, Mack CL. High-dose IgG therapy mitigates bile duct-targeted inflammation and obstruction in a mouse model of biliary atresia. Pediatr Res. 2014 Jul; 76(1):72-80. PMID: 24727948.
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Sambrotta M, Strautnieks S, Papouli E, Rushton P, Clark BE, Parry DA, Logan CV, Newbury LJ, Kamath BM, Ling S, Grammatikopoulos T, Wagner BE, Magee JC, Sokol RJ, Mieli-Vergani G, Smith JD, Johnson CA, McClean P, Simpson MA, Knisely AS, Bull LN, Thompson RJ. Mutations in TJP2 cause progressive cholestatic liver disease. Nat Genet. 2014 Apr; 46(4):326-8. PMID: 24614073.
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Gallagher RC, Lam C, Wong D, Cederbaum S, Sokol RJ. Significant hepatic involvement in patients with ornithine transcarbamylase deficiency. J Pediatr. 2014 Apr; 164(4):720-725.e6. PMID: 24485820.
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Mazariegos G, Shneider B, Burton B, Fox IJ, Hadzic N, Kishnani P, Morton DH, McIntire S, Sokol RJ, Summar M, White D, Chavanon V, Vockley J. Liver transplantation for pediatric metabolic disease. Mol Genet Metab. 2014 Apr; 111(4):418-27. PMID: 24495602.
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Sundaram SS, Sokol RJ, Capocelli KE, Pan Z, Sullivan JS, Robbins K, Halbower AC. Obstructive sleep apnea and hypoxemia are associated with advanced liver histology in pediatric nonalcoholic fatty liver disease. J Pediatr. 2014 Apr; 164(4):699-706.e1. PMID: 24321532.
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Mealer M, Kittelson J, Thompson BT, Wheeler AP, Magee JC, Sokol RJ, Moss M, Kahn MG. Remote source document verification in two national clinical trials networks: a pilot study. PLoS One. 2013; 8(12):e81890. PMID: 24349149.
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El Kasmi KC, Anderson AL, Devereaux MW, Vue PM, Zhang W, Setchell KD, Karpen SJ, Sokol RJ. Phytosterols promote liver injury and Kupffer cell activation in parenteral nutrition-associated liver disease. Sci Transl Med. 2013 Oct 09; 5(206):206ra137. PMID: 24107776.
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Schwarz KB, Haber BH, Rosenthal P, Mack CL, Moore J, Bove K, Bezerra JA, Karpen SJ, Kerkar N, Shneider BL, Turmelle YP, Whitington PF, Molleston JP, Murray KF, Ng VL, Romero R, Wang KS, Sokol RJ, Magee JC. Extrahepatic anomalies in infants with biliary atresia: results of a large prospective North American multicenter study. Hepatology. 2013 Nov; 58(5):1724-31. PMID: 23703680.
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Molleston JP, Sokol RJ, Karnsakul W, Miethke A, Horslen S, Magee JC, Romero R, Squires RH, Van Hove JL. Evaluation of the child with suspected mitochondrial liver disease. J Pediatr Gastroenterol Nutr. 2013 Sep; 57(3):269-76. PMID: 23783016.
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Lee WS, Sokol RJ. Mitochondrial hepatopathies: advances in genetics, therapeutic approaches, and outcomes. J Pediatr. 2013 Oct; 163(4):942-8. PMID: 23810725.
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Sundaram SS, Alonso EM, Haber B, Magee JC, Fredericks E, Kamath B, Kerkar N, Rosenthal P, Shepherd R, Limbers C, Varni JW, Robuck P, Sokol RJ. Health related quality of life in patients with biliary atresia surviving with their native liver. J Pediatr. 2013 Oct; 163(4):1052-7.e2. PMID: 23746866.
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Colson SB, Siparsky GL, Capocelli KE, Pan Z, Sokol RJ, Hoffenberg EJ. Inflammatory bowel disease in pediatric patients with cerebral palsy. J Pediatr Gastroenterol Nutr. 2013 Jun; 56(6):e50. PMID: 23518488.
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Mack CL, Anderson KM, Aubrey MT, Rosenthal P, Sokol RJ, Freed BM. Lack of HLA predominance and HLA shared epitopes in biliary Atresia. Springerplus. 2013 Dec; 2(1):42. PMID: 23505615.
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Mack CL, Feldman AG, Sokol RJ. Clues to the etiology of bile duct injury in biliary atresia. Semin Liver Dis. 2012 Nov; 32(4):307-16. PMID: 23397531.
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Feldman AG, Sokol RJ. Neonatal Cholestasis. Neoreviews. 2013 Feb 01; 14(2). PMID: 24244109.
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Feldman A, Sokol RJ. Alpha-1-Antitrypsin Deficiency: An Important Cause of Pediatric Liver Disease. Lung Health Prof Mag. 2013; 4(2):8-11. PMID: 27019872.
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Lu BR, Zhang S, Narkewicz MR, Belle SH, Squires RH, Sokol RJ. Evaluation of the liver injury unit scoring system to predict survival in a multinational study of pediatric acute liver failure. J Pediatr. 2013 May; 162(5):1010-6.e1-4. PMID: 23260095.
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Kamath BM, Piccoli DA, Magee JC, Sokol RJ. Pancreatic insufficiency is not a prevalent problem in Alagille syndrome. J Pediatr Gastroenterol Nutr. 2012 Nov; 55(5):612-4. PMID: 22614108.
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Nel E, Sokol RJ, Comparcola D, Nobili V, Hardikar W, Gana JC, Abarca K, Wu JF, Chang MH, Renner JK. Viral hepatitis in children. J Pediatr Gastroenterol Nutr. 2012 Nov; 55(5):500-5. PMID: 22983372.
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Shneider BL, Abel B, Haber B, Karpen SJ, Magee JC, Romero R, Schwarz K, Bass LM, Kerkar N, Miethke AG, Rosenthal P, Turmelle Y, Robuck PR, Sokol RJ. Portal hypertension in children and young adults with biliary atresia. J Pediatr Gastroenterol Nutr. 2012 Nov; 55(5):567-73. PMID: 22903006.
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Shneider BL, Magee JC, Bezerra JA, Haber B, Karpen SJ, Raghunathan T, Rosenthal P, Schwarz K, Suchy FJ, Kerkar N, Turmelle Y, Whitington PF, Robuck PR, Sokol RJ. Efficacy of fat-soluble vitamin supplementation in infants with biliary atresia. Pediatrics. 2012 Sep; 130(3):e607-14. PMID: 22891232.
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Miller MR, Sokol RJ, Narkewicz MR, Sontag MK. Pulmonary function in individuals who underwent liver transplantation: from the US cystic fibrosis foundation registry. Liver Transpl. 2012 May; 18(5):585-93. PMID: 22271602.
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Shamoon H, Center D, Davis P, Tuchman M, Ginsberg H, Califf R, Stephens D, Mellman T, Verbalis J, Nadler L, Shekhar A, Ford D, Rizza R, Shaker R, Brady K, Murphy B, Cronstein B, Hochman J, Greenland P, Orwoll E, Sinoway L, Greenberg H, Jackson R, Coller B, Topol E, Guay-Woodford L, Runge M, Clark R, McClain D, Selker H, Lowery C, Dubinett S, Berglund L, Cooper D, Firestein G, Johnston SC, Solway J, Heubi J, Sokol R, Nelson D, Tobacman L, Rosenthal G, Aaronson L, Barohn R, Kern P, Sullivan J, Shanley T, Blazar B, Larson R, FitzGerald G, Reis S, Pearson T, Buchanan T, McPherson D, Brasier A, Toto R, Disis M, Drezner M, Bernard G, Clore J, Evanoff B, Imperato-McGinley J, Sherwin R, Pulley J. Preparedness of the CTSA's structural and scientific assets to support the mission of the National Center for Advancing Translational Sciences (NCATS). Clin Transl Sci. 2012 Apr; 5(2):121-9. PMID: 22507116.
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El Kasmi KC, Anderson AL, Devereaux MW, Fillon SA, Harris JK, Lovell MA, Finegold MJ, Sokol RJ. Toll-like receptor 4-dependent Kupffer cell activation and liver injury in a novel mouse model of parenteral nutrition and intestinal injury. Hepatology. 2012 May; 55(5):1518-28. PMID: 22120983.
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Sullivan JS, Sundaram SS, Pan Z, Sokol RJ. Parenteral nutrition supplementation in biliary atresia patients listed for liver transplantation. Liver Transpl. 2012 Jan; 18(1):120-8. PMID: 21987426.
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Ng VL, Alonso EM, Bucuvalas JC, Cohen G, Limbers CA, Varni JW, Mazariegos G, Magee J, McDiarmid SV, Anand R. Health status of children alive 10 years after pediatric liver transplantation performed in the US and Canada: report of the studies of pediatric liver transplantation experience. J Pediatr. 2012 May; 160(5):820-6.e3. PMID: 22192813.
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Superina R , Magee JC, Brandt ML, Healey PJ, Tiao G, Ryckman F, Karrer FM, Iyer K, Fecteau A, West K, Burns RC, Flake A, Lee H, Lowell JA, Dillon P, Colombani P, Ricketts R, Li Y, Moore J, Wang KD and the Childhood Liver Disease Research and Education Network (…Sokol RJ…). . The anatomic pattern of biliary atresia identified at time of Kasai hepatoportoenterostomy and early postoperative clearance of jaundice are significant predictors of transplant-free survival. Annals Surg. 2011; 254:577-585.
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Martin SR, Alvarez F, Anand R, Song C, Yin W, SPLIT Research Group (…Sokol RJ…). . Outcomes in children who underwent transplantation for autoimmune hepatitis. Liver Transpl. 2011; 17:393-401.
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Simpson M, Brady H, Yin X, Seifert J, Barriga K, Hoffman M, Bugawan T, Bar?n AE, Sokol RJ, Eisenbarth G, Erlich H, Rewers M, Norris JM. No association of vitamin D intake or 25-hydroxyvitamin D levels in childhood with risk of islet autoimmunity and type 1 diabetes: the Diabetes Autoimmunity Study in the Young (DAISY). Diabetologia. 2011 Nov; 54(11):2779-88. PMID: 21858504.
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Li M, Riddle SR, Frid MG, El Kasmi KC, McKinsey TA, Sokol RJ, Strassheim D, Meyrick B, Yeager ME, Flockton AR, McKeon BA, Lemon DD, Horn TR, Anwar A, Barajas C, Stenmark KR. Emergence of fibroblasts with a proinflammatory epigenetically altered phenotype in severe hypoxic pulmonary hypertension. J Immunol. 2011 Sep 01; 187(5):2711-22. PMID: 21813768.
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Limbers CA, Neighbors K, Martz K, Bucuvalas JC, Webb T, Varni JW, Alonso EM, on behalf of Studies of Pediatric Liver Transplantation Functional Outcomes Group (FOG) (..Sokol RJ..). . Health-related quality of life in pediatric liver transpant recipients compared to other chronic disease groups. Pediatr Transplant. 2011; 15:245-253.
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Russo P, Magee JC, Boitnott J, Bove KE, Raghunathan T, Finegold M, Haas J, Jaffe R, Kim GE, Magid M, Melin-Aldana H, White F, Whitington PF, Sokol RJ. Design and validation of the biliary atresia research consortium histologic assessment system for cholestasis in infancy. Clin Gastroenterol Hepatol. 2011 Apr; 9(4):357-362.e2. PMID: 21238606.
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Campsen J, Zimmerman MA, Narkewicz MR, Sokol RJ, Mandell MS, Kam I, Dovel D, Karrer FM. Choledochoduodenostomy in pediatric liver transplantation. Pediatr Transplant. 2011 May; 15(3):237-9. PMID: 21214697.
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Varni JW, Limbers CA, Sorensen LG, Neighbors K, Martz K, Bucuvalas JC, Alonso EM. PedsQL? Cognitive Functioning Scale in pediatric liver transplant recipients: feasibility, reliability, and validity. Qual Life Res. 2011 Aug; 20(6):913-21. PMID: 21184184.
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Alsultan A, Sokol RJ, Lovell MA, Thurman G, Ambruso DR. Long term G-CSF-induced remission of ulcerative colitis-like inflammatory bowel disease in a patient with glycogen storage disease Ib and evaluation of associated neutrophil function. Pediatr Blood Cancer. 2010 Dec 15; 55(7):1410-3. PMID: 20830779.
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Law YM, Mack CL, Sokol RJ, Rice M, Parsley L, Ivy D. Cardiopulmonary manifestations of portovenous shunts from congenital absence of the portal vein: pulmonary hypertension and pulmonary vascular dilatation. Pediatr Transplant. 2011 Dec; 15(8):E162-8. PMID: 20565694.
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Soden JS, Lovell MA, Brown K, Partrick DA, Sokol RJ. Failure of resolution of portal fibrosis during omega-3 fatty acid lipid emulsion therapy in two patients with irreversible intestinal failure. J Pediatr. 2010 Feb; 156(2):327-31. PMID: 20105644.
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Sokol RJ. Reloading against rare liver diseases. J Pediatr Gastroenterol Nutr. 2010 Jan; 50(1):9-10. PMID: 19915492.
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Whitworth JR, Ivy DD, Gralla J, Narkewicz MR, Sokol RJ. Pulmonary vascular complications in asymptomatic children with portal hypertension. J Pediatr Gastroenterol Nutr. 2009 Nov; 49(5):607-12. PMID: 19820411.
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Alonso EM, Limbers CA, Neighbors K, Martz K, Bucuvalas JC, Webb T, Varni JW. Cross-sectional analysis of health-related quality of life in pediatric liver transplant recipients. J Pediatr. 2010 Feb; 156(2):270-6.e1. PMID: 19846110.
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Rand EB, Karpen SJ, Kelly S, Mack CL, Malatack JJ, Sokol RJ, Whitington PF. Treatment of neonatal hemochromatosis with exchange transfusion and intravenous immunoglobulin. J Pediatr. 2009 Oct; 155(4):566-71. PMID: 19560784.
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Sokol RJ. Biliary atresia screening: why, when, and how? Pediatrics. 2009 May; 123(5):e951-2. PMID: 19403487.
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Soden JS, Narkewicz MR, Haas JE, Sokol RJ. Hepatic veno-occlusive disease and human herpes virus 7 infection in primary agammaglobulinemia. J Pediatr. 2009 Feb; 154(2):299-302. PMID: 19150678.
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Kurbegov AC, Sokol RJ. Hepatitis B therapy in children. Expert Rev Gastroenterol Hepatol. 2009 Feb; 3(1):39-49. PMID: 19210112.
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Ng VL, Fecteau A, Shepherd R, Magee J, Bucuvalas J, Alonso E, McDiarmid S, Cohen G, Anand R. Outcomes of 5-year survivors of pediatric liver transplantation: report on 461 children from a north american multicenter registry. Pediatrics. 2008 Dec; 122(6):e1128-35. PMID: 19047213.
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Gumpricht E, Devereaux MW, Dahl R, Soden JS, Sparagna GC, Leonard SW, Traber MG, Sokol RJ. Resistance of young rat hepatic mitochondria to bile acid-induced permeability transition: potential role of alpha-tocopherol. Pediatr Res. 2008 Nov; 64(5):498-504. PMID: 18596569.
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Lu BR, Gralla J, Liu E, Dobyns EL, Narkewicz MR, Sokol RJ. Evaluation of a scoring system for assessing prognosis in pediatric acute liver failure. Clin Gastroenterol Hepatol. 2008 Oct; 6(10):1140-5. PMID: 18928939.
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Sundaram SS, Bove KE, Lovell MA, Sokol RJ. Mechanisms of disease: Inborn errors of bile acid synthesis. Nat Clin Pract Gastroenterol Hepatol. 2008 Aug; 5(8):456-68. PMID: 18577977.
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Laguna TA, Sontag MK, Osberg I, Wagener JS, Accurso FJ, Sokol RJ. Decreased total serum coenzyme-Q10 concentrations: a longitudinal study in children with cystic fibrosis. J Pediatr. 2008 Sep; 153(3):402-7. PMID: 18534204.
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Petersen C, Harder D, Abola Z, Alberti D, Becker T, Chardot C, Davenport M, Deutschmann A, Khelif K, Kobayashi H, Kvist N, Leonhardt J, Melter M, Pakarinen M, Pawlowska J, Petersons A, Pfister ED, Rygl M, Schreiber R, Sokol R, Ure B, Veiga C, Verkade H, Wildhaber B, Yerushalmi B, Kelly D. European biliary atresia registries: summary of a symposium. Eur J Pediatr Surg. 2008 Apr; 18(2):111-6. PMID: 18437656.
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Sokol RJ. Swiss outcomes in biliary atresia: are there lessons to be learned? J Pediatr Gastroenterol Nutr. 2008 Mar; 46(3):238-40. PMID: 18376239.
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Sokol RJ. Corticosteroid treatment in biliary atresia: Tonic or toast? Hepatology. 2007 Dec; 46(6):1675-8. PMID: 18046714.
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Sundaram SS, Sokol RJ. The Multiple Facets of ABCB4 (MDR3) Deficiency. Curr Treat Options Gastroenterol. 2007 Dec; 10(6):495-503. PMID: 18221610.
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Sokol RJ, Daniels SR. The future of pediatrics: a festschrift for M. Douglas Jones, Jr, MD. J Pediatr. 2007 Nov; 151(5 Suppl):S1-2. PMID: 17950315.
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DeRusso PA, Ye W, Shepherd R, Haber BA, Shneider BL, Whitington PF, Schwarz KB, Bezerra JA, Rosenthal P, Karpen S, Squires RH, Magee JC, Robuck PR, Sokol RJ. Growth failure and outcomes in infants with biliary atresia: a report from the Biliary Atresia Research Consortium. Hepatology. 2007 Nov; 46(5):1632-8. PMID: 17929308.
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Woodruff SA, Sokol RJ. Colonic polyp as lead point for intussusception. J Pediatr Gastroenterol Nutr. 2007 Sep; 45(3):279-80. PMID: 17873737.
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Soden JS, Devereaux MW, Haas JE, Gumpricht E, Dahl R, Gralla J, Traber MG, Sokol RJ. Subcutaneous vitamin E ameliorates liver injury in an in vivo model of steatocholestasis. Hepatology. 2007 Aug; 46(2):485-95. PMID: 17659596.
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Sokol RJ, Shepherd RW, Superina R, Bezerra JA, Robuck P, Hoofnagle JH. Screening and outcomes in biliary atresia: summary of a National Institutes of Health workshop. Hepatology. 2007 Aug; 46(2):566-81. PMID: 17661405.
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Lee WS, Sokol RJ. Liver disease in mitochondrial disorders. Semin Liver Dis. 2007 Aug; 27(3):259-73. PMID: 17682973.
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Belkind-Gerson J, Guarino A, Sokol RJ. The 2008 World Congress Working Group Reports: an opportunity for a worldwide consensus to affect children's digestive health. J Pediatr Gastroenterol Nutr. 2007 Aug; 45(2):172-3. PMID: 17667709.
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Kahn MG, Kaplan D, Sokol RJ, DiLaura RP. Configuration challenges: implementing translational research policies in electronic medical records. Acad Med. 2007 Jul; 82(7):661-9. PMID: 17595562.
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Papas KA, Sontag MK, Pardee C, Sokol RJ, Sagel SD, Accurso FJ, Wagener JS. A pilot study on the safety and efficacy of a novel antioxidant rich formulation in patients with cystic fibrosis. J Cyst Fibros. 2008 Jan; 7(1):60-7. PMID: 17569601.
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Lee WS, Sokol RJ. Mitochondrial hepatopathies: advances in genetics and pathogenesis. Hepatology. 2007 Jun; 45(6):1555-65. PMID: 17538929.
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Sokol RJ. Selection bias and vitamin E status in cystic fibrosis. J Pediatr. 2007 May; 150(5):e85; author reply e85-6. PMID: 17452206.
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Mack CL, Falta MT, Sullivan AK, Karrer F, Sokol RJ, Freed BM, Fontenot AP. Oligoclonal expansions of CD4+ and CD8+ T-cells in the target organ of patients with biliary atresia. Gastroenterology. 2007 Jul; 133(1):278-87. PMID: 17631149.
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Brady H, Lamb MM, Sokol RJ, Ross CA, Seifert JA, Rewers MJ, Norris JM. Plasma micronutrients are associated with dietary intake and environmental tobacco smoke exposure in a paediatric population. Public Health Nutr. 2007 Jul; 10(7):712-8. PMID: 17381951.
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Sokol RJ. Presentation of the 2006 Shwachman Award to Judith M. Sondheimer, MD. J Pediatr Gastroenterol Nutr. 2007 Jan; 44(1):1. PMID: 17204942.
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Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, Ueno Y, Gill RG. Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia. Hepatology. 2006 Nov; 44(5):1231-9. PMID: 17058262.
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Barnes BH, Narkewicz MR, Sokol RJ. Spontaneous perforation of the bile duct in a toddler: the role of endoscopic retrograde cholangiopancreatography in diagnosis and therapy. J Pediatr Gastroenterol Nutr. 2006 Nov; 43(5):695-7. PMID: 17130751.
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Whitworth JR, Mack CL, O'Connor JA, Narkewicz MR, Mengshol S, Sokol RJ. Acute hepatitis and liver failure associated with influenza A infection in children. J Pediatr Gastroenterol Nutr. 2006 Oct; 43(4):536-8. PMID: 17033532.
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Stene LC, Honeyman MC, Hoffenberg EJ, Haas JE, Sokol RJ, Emery L, Taki I, Norris JM, Erlich HA, Eisenbarth GS, Rewers M. Rotavirus infection frequency and risk of celiac disease autoimmunity in early childhood: a longitudinal study. Am J Gastroenterol. 2006 Oct; 101(10):2333-40. PMID: 17032199.
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Cantin AM, White TB, Cross CE, Forman HJ, Sokol RJ, Borowitz D. Antioxidants in cystic fibrosis. Conclusions from the CF antioxidant workshop, Bethesda, Maryland, November 11-12, 2003. Free Radic Biol Med. 2007 Jan 01; 42(1):15-31. PMID: 17157190.
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Mustacich DJ, Leonard SW, Devereaux MW, Sokol RJ, Traber MG. Alpha-tocopherol regulation of hepatic cytochrome P450s and ABC transporters in rats. Free Radic Biol Med. 2006 Oct 01; 41(7):1069-78. PMID: 16962932.
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Sokol RJ, Devereaux M, Dahl R, Gumpricht E. "Let there be bile"--understanding hepatic injury in cholestasis. J Pediatr Gastroenterol Nutr. 2006 Jul; 43 Suppl 1:S4-9. PMID: 16819400.
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Squires RH, Shneider BL, Bucuvalas J, Alonso E, Sokol RJ, Narkewicz MR, Dhawan A, Rosenthal P, Rodriguez-Baez N, Murray KF, Horslen S, Martin MG, Lopez MJ, Soriano H, McGuire BM, Jonas MM, Yazigi N, Shepherd RW, Schwarz K, Lobritto S, Thomas DW, Lavine JE, Karpen S, Ng V, Kelly D, Simonds N, Hynan LS. Acute liver failure in children: the first 348 patients in the pediatric acute liver failure study group. J Pediatr. 2006 May; 148(5):652-658. PMID: 16737880.
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Shneider BL, Brown MB, Haber B, Whitington PF, Schwarz K, Squires R, Bezerra J, Shepherd R, Rosenthal P, Hoofnagle JH, Sokol RJ. A multicenter study of the outcome of biliary atresia in the United States, 1997 to 2000. J Pediatr. 2006 Apr; 148(4):467-474. PMID: 16647406.
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Hoofnagle JH, Sokol RJ. Neonatal screening for biliary atresia. Hepatology. 2006 Apr; 43(4):646. PMID: 16557564.
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Narkewicz MR, Kasaragod A, Lucia MS, Pflummer S, Sokol RJ, Stenmark KR. Connective tissue growth factor expression is increased in biliary epithelial cells in biliary atresia. J Pediatr Surg. 2005 Nov; 40(11):1721-5. PMID: 16291159.
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Feranchak AP, Gralla J, King R, Ramirez RO, Corkill M, Narkewicz MR, Sokol RJ. Comparison of indices of vitamin A status in children with chronic liver disease. Hepatology. 2005 Oct; 42(4):782-92. PMID: 16175620.
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Whitworth JR, Sokol RJ. Hepato-portopulmonary disorders--not just in adults! J Pediatr Gastroenterol Nutr. 2005 Oct; 41(4):393-5. PMID: 16205504.
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Utterson EC, Shepherd RW, Sokol RJ, Bucuvalas J, Magee JC, McDiarmid SV, Anand R. Biliary atresia: clinical profiles, risk factors, and outcomes of 755 patients listed for liver transplantation. J Pediatr. 2005 Aug; 147(2):180-5. PMID: 16126046.
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Sokol RJ, Dahl R, Devereaux MW, Yerushalmi B, Kobak GE, Gumpricht E. Human hepatic mitochondria generate reactive oxygen species and undergo the permeability transition in response to hydrophobic bile acids. J Pediatr Gastroenterol Nutr. 2005 Aug; 41(2):235-43. PMID: 16056106.
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Liu E, MacKenzie T, Dobyns EL, Parikh CR, Karrer FM, Narkewicz MR, Sokol RJ. Characterization of acute liver failure and development of a continuous risk of death staging system in children. J Hepatol. 2006 Jan; 44(1):134-41. PMID: 16169116.
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Condino AA, Ivy DD, O'Connor JA, Narkewicz MR, Mengshol S, Whitworth JR, Claussen L, Doran A, Sokol RJ. Portopulmonary hypertension in pediatric patients. J Pediatr. 2005 Jul; 147(1):20-6. PMID: 16027687.
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Norris JM, Barriga K, Hoffenberg EJ, Taki I, Miao D, Haas JE, Emery LM, Sokol RJ, Erlich HA, Eisenbarth GS, Rewers M. Risk of celiac disease autoimmunity and timing of gluten introduction in the diet of infants at increased risk of disease. JAMA. 2005 May 18; 293(19):2343-51. PMID: 15900004.
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Mack CL, Tucker RM, Sokol RJ, Kotzin BL. Armed CD4+ Th1 effector cells and activated macrophages participate in bile duct injury in murine biliary atresia. Clin Immunol. 2005 May; 115(2):200-9. PMID: 15885644.
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Kobak GE, Dahl R, Devereaux MW, Gumpricht E, Traber M, Doctor RB, Sokol RJ. Increased susceptibility of fat-laden Zucker-rat hepatocytes to bile acid-induced oncotic necrosis: an in vitro model of steatocholestasis. J Lab Clin Med. 2005 May; 145(5):247-62. PMID: 15902097.
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Mack CL, Sokol RJ. Unraveling the pathogenesis and etiology of biliary atresia. Pediatr Res. 2005 May; 57(5 Pt 2):87R-94R. PMID: 15817506.
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Das BB, Narkewicz MR, Sokol RJ, Chen YT, Bali D, Li SC, Matthews MR, Mierau GW, Ivy DD. Amylopectinosis disease isolated to the heart with normal glycogen branching enzyme activity and gene sequence. Pediatr Transplant. 2005 Apr; 9(2):261-5. PMID: 15787805.
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Leonard SW, Gumpricht E, Devereaux MW, Sokol RJ, Traber MG. Quantitation of rat liver vitamin E metabolites by LC-MS during high-dose vitamin E administration. J Lipid Res. 2005 May; 46(5):1068-75. PMID: 15722564.
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Sokol RJ, Mack CL. Optimizing outcomes and bridging biliary atresia into adulthood. Hepatology. 2005 Feb; 41(2):231-3. PMID: 15657917.
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Gumpricht E, Dahl R, Devereaux MW, Sokol RJ. Licorice compounds glycyrrhizin and 18beta-glycyrrhetinic acid are potent modulators of bile acid-induced cytotoxicity in rat hepatocytes. J Biol Chem. 2005 Mar 18; 280(11):10556-63. PMID: 15642733.
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Gumpricht E, Devereaux MW, Traber M, Sokol RJ. Enrichment of rat hepatic organelles by vitamin E administered subcutaneously. Free Radic Biol Med. 2004 Dec 01; 37(11):1712-7. PMID: 15528030.
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Kobak GE, MacKenzie T, Sokol RJ, Narkewicz MR. Interferon treatment for chronic hepatitis B: enhanced response in children 5 years old or younger. J Pediatr. 2004 Sep; 145(3):340-5. PMID: 15343187.
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Mack CL, Tucker RM, Sokol RJ, Karrer FM, Kotzin BL, Whitington PF, Miller SD. Biliary atresia is associated with CD4+ Th1 cell-mediated portal tract inflammation. Pediatr Res. 2004 Jul; 56(1):79-87. PMID: 15128911.
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Hoffenberg EJ, Emery LM, Barriga KJ, Bao F, Taylor J, Eisenbarth GS, Haas JE, Sokol RJ, Taki I, Norris JM, Rewers M. Clinical features of children with screening-identified evidence of celiac disease. Pediatrics. 2004 May; 113(5):1254-9. PMID: 15121938.
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Zhang DY, Sabla G, Shivakumar P, Tiao G, Sokol RJ, Mack C, Shneider BL, Aronow B, Bezerra JA. Coordinate expression of regulatory genes differentiates embryonic and perinatal forms of biliary atresia. Hepatology. 2004 Apr; 39(4):954-62. PMID: 15057899.
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Gumpricht E, Dahl R, Devereaux MW, Sokol RJ. Beta-carotene prevents bile acid-induced cytotoxicity in the rat hepatocyte: Evidence for an antioxidant and anti-apoptotic role of beta-carotene in vitro. Pediatr Res. 2004 May; 55(5):814-21. PMID: 14764912.
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Sokol RJ. Re: Article by Kamath et al.-"Facial features in Alagille Syndrome". Am J Med Genet A. 2004 Jan 15; 124A(2):220-1; reply 222-3. PMID: 14699626.
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Kurbegov AC, Setchell KD, Haas JE, Mierau GW, Narkewicz M, Bancroft JD, Karrer F, Sokol RJ. Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile. Gastroenterology. 2003 Oct; 125(4):1227-34. PMID: 14517804.
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Kauffman LD, Sokol RJ, Jones RH, Awad JA, Rewers MJ, Norris JM. Urinary F2-isoprostanes in young healthy children at risk for type 1 diabetes mellitus. Free Radic Biol Med. 2003 Sep 15; 35(6):551-7. PMID: 12957647.
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Burch JM, Sokol RJ, Narkewicz MR, Reichlin M, Frank MB, MacKenzie T, Lee LA. Autoantibodies in mothers of children with neonatal liver disease. J Pediatr Gastroenterol Nutr. 2003 Sep; 37(3):262-7. PMID: 12960647.
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Hoffenberg EJ, MacKenzie T, Barriga KJ, Eisenbarth GS, Bao F, Haas JE, Erlich H, Bugawan Tl Tl, Sokol RJ, Taki I, Norris JM, Rewers M. A prospective study of the incidence of childhood celiac disease. J Pediatr. 2003 Sep; 143(3):308-14. PMID: 14517510.
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Gillis LA, Sokol RJ. Gastrointestinal manifestations of mitochondrial disease. Gastroenterol Clin North Am. 2003 Sep; 32(3):789-817, v. PMID: 14562575.
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Sokol RJ, Mack C, Narkewicz MR, Karrer FM. Pathogenesis and outcome of biliary atresia: current concepts. J Pediatr Gastroenterol Nutr. 2003 Jul; 37(1):4-21. PMID: 12827000.
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Narkewicz MR, Sondheimer HM, Ziegler JW, Otanni Y, Lorts A, Shaffer EM, Horgan JG, Sokol RJ. Hepatic dysfunction following the Fontan procedure. J Pediatr Gastroenterol Nutr. 2003 Mar; 36(3):352-7. PMID: 12604973.
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Nadeau K, Klingensmith G, Sokol RJ. Case report: nonalcoholic steatohepatitis in a teenage girl with type 2 diabetes. Curr Opin Pediatr. 2003 Feb; 15(1):127-31. PMID: 12544284.
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Sokol RJ. New North American research network focuses on biliary atresia and neonatal liver disease. J Pediatr Gastroenterol Nutr. 2003 Jan; 36(1):1. PMID: 12537011.
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Yerushalmi B, Sokol RJ, Narkewicz MR, Smith D, Ashmead JW, Wenger DA. Niemann-pick disease type C in neonatal cholestasis at a North American Center. J Pediatr Gastroenterol Nutr. 2002 Jul; 35(1):44-50. PMID: 12142809.
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Gumpricht E, Dahl R, Yerushalmi B, Devereaux MW, Sokol RJ. Nitric oxide ameliorates hydrophobic bile acid-induced apoptosis in isolated rat hepatocytes by non-mitochondrial pathways. J Biol Chem. 2002 Jul 12; 277(28):25823-30. PMID: 12006578.
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Sokol RJ. Introduction to the pediatric liver research agenda: a blueprint for the future. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 1:S2-3. PMID: 12151812.
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Sokol RJ. Liver cell injury and fibrosis. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 1:S7-10. PMID: 12151814.
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Lee LA, Sokol RJ, Buyon JP. Hepatobiliary disease in neonatal lupus: prevalence and clinical characteristics in cases enrolled in a national registry. Pediatrics. 2002 Jan; 109(1):E11. PMID: 11773579.
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Sokol RJ, Mack C. Etiopathogenesis of biliary atresia. Semin Liver Dis. 2001 Nov; 21(4):517-24. PMID: 11745039.
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Feranchak AP, Sokol RJ. Cholangiocyte biology and cystic fibrosis liver disease. Semin Liver Dis. 2001 Nov; 21(4):471-88. PMID: 11745036.
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Vu TH, Tanji K, Holve SA, Bonilla E, Sokol RJ, Snyder RD, Fiore S, Deutsch GH, Dimauro S, De Vivo D. Navajo neurohepatopathy: a mitochondrial DNA depletion syndrome? Hepatology. 2001 Jul; 34(1):116-20. PMID: 11431741.
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Sokol RJ, Straka MS, Dahl R, Devereaux MW, Yerushalmi B, Gumpricht E, Elkins N, Everson G. Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids. Pediatr Res. 2001 Apr; 49(4):519-31. PMID: 11264436.
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Yerushalmi B, Dahl R, Devereaux MW, Gumpricht E, Sokol RJ. Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition. Hepatology. 2001 Mar; 33(3):616-26. PMID: 11230742.
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Sokol RJ. American Liver Foundation releases Pediatric Liver Research Agenda-2000. J Pediatr Gastroenterol Nutr. 2001 Mar; 32(3):236. PMID: 11345169.
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Sokol RJ, Stamps R, Booker DJ. IgG2 class red cell antibodies and autoimmune haemolysis. Haematologia (Budap). 2001; 31(1):1-6. PMID: 11345398.
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Ingram JD, Yerushalmi B, Connell J, Karrer FM, Tyson RW, Sokol RJ. Hepatoblastoma in a neonate: a hypervascular presentation mimicking hemangioendothelioma. Pediatr Radiol. 2000 Nov; 30(11):794-7. PMID: 11100498.
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Hoffenberg EJ, Bao F, Eisenbarth GS, Uhlhorn C, Haas JE, Sokol RJ, Rewers M. Transglutaminase antibodies in children with a genetic risk for celiac disease. J Pediatr. 2000 Sep; 137(3):356-60. PMID: 10969260.
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Sokol RJ. The chronic disease of childhood obesity: the sleeping giant has awakened. J Pediatr. 2000 Jun; 136(6):711-3. PMID: 10905886.
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Gumpricht E, Devereaux MW, Dahl RH, Sokol RJ. Glutathione status of isolated rat hepatocytes affects bile acid-induced cellular necrosis but not apoptosis. Toxicol Appl Pharmacol. 2000 Apr 01; 164(1):102-11. PMID: 10739750.
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Sokal EM, Sokol R, Cormier V, Lacaille F, McKiernan P, Van Spronsen FJ, Bernard O, Saudubray JM. Liver transplantation in mitochondrial respiratory chain disorders. Eur J Pediatr. 1999 Dec; 158 Suppl 2:S81-4. PMID: 10603105.
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Feranchak AP, Sontag MK, Wagener JS, Hammond KB, Accurso FJ, Sokol RJ. Prospective, long-term study of fat-soluble vitamin status in children with cystic fibrosis identified by newborn screen. J Pediatr. 1999 Nov; 135(5):601-10. PMID: 10547249.
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Holve S, Hu D, Shub M, Tyson RW, Sokol RJ. Liver disease in Navajo neuropathy. J Pediatr. 1999 Oct; 135(4):482-93. PMID: 10518083.
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Yerushalmi B, Sokol RJ, Narkewicz MR, Smith D, Karrer FM. Use of rifampin for severe pruritus in children with chronic cholestasis. J Pediatr Gastroenterol Nutr. 1999 Oct; 29(4):442-7. PMID: 10512405.
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Feranchak AP, Sokol RJ. How many wrongs make a right (or a left)? Vertebrate asymmetry unraveled. J Pediatr Gastroenterol Nutr. 1999 Mar; 28(3):239-41. PMID: 10067719.
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Narkewicz MR, Krebs N, Karrer F, Orban-Eller K, Sokol RJ. Correction of hypozincemia following liver transplantation in children is associated with reduced urinary zinc loss. Hepatology. 1999 Mar; 29(3):830-3. PMID: 10051486.
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Sokol RJ. Alagille syndrome: A nutritional niche for Notch. J Pediatr. 1999 Feb; 134(2):136-8. PMID: 9931516.
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Sokol RJ, Durie PR. Recommendations for management of liver and biliary tract disease in cystic fibrosis. Cystic Fibrosis Foundation Hepatobiliary Disease Consensus Group. J Pediatr Gastroenterol Nutr. 1999; 28 Suppl 1:S1-13. PMID: 9934970.
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Sokol RJ, Treem WR. Mitochondria and childhood liver diseases. J Pediatr Gastroenterol Nutr. 1999 Jan; 28(1):4-16. PMID: 9890461.
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Harned RK, Thompson HR, Kumpe DA, Narkewicz MR, Sokol RJ. Partial splenic embolization in five children with hypersplenism: effects of reduced-volume embolization on efficacy and morbidity. Radiology. 1998 Dec; 209(3):803-6. PMID: 9844678.
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Feranchak AP, Tyson RW, Narkewicz MR, Karrer FM, Sokol RJ. Fulminant Epstein-Barr viral hepatitis: orthotopic liver transplantation and review of the literature. Liver Transpl Surg. 1998 Nov; 4(6):469-76. PMID: 9791157.
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Setchell KD, Schwarz M, O'Connell NC, Lund EG, Davis DL, Lathe R, Thompson HR, Weslie Tyson R, Sokol RJ, Russell DW. Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease. J Clin Invest. 1998 Nov 01; 102(9):1690-703. PMID: 9802883.
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Sokol RJ, Devereaux MW, Khandwala R. Effect of oxypurinol, a xanthine oxidase inhibitor, on hepatic injury in the bile duct-ligated rat. Pediatr Res. 1998 Sep; 44(3):397-401. PMID: 9727720.
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Shivaram KN, Winklhofer-Roob BM, Straka MS, Devereaux MW, Everson G, Mierau GW, Sokol RJ. The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria. Free Radic Biol Med. 1998 Sep; 25(4-5):480-92. PMID: 9741584.
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Tyler KL, Sokol RJ, Oberhaus SM, Le M, Karrer FM, Narkewicz MR, Tyson RW, Murphy JR, Low R, Brown WR. Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts. Hepatology. 1998 Jun; 27(6):1475-82. PMID: 9620316.
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Burwinkel B, Amat L, Gray RG, Matsuo N, Muroya K, Narisawa K, Sokol RJ, Vilaseca MA, Kilimann MW. Variability of biochemical and clinical phenotype in X-linked liver glycogenosis with mutations in the phosphorylase kinase PHKA2 gene. Hum Genet. 1998 Apr; 102(4):423-9. PMID: 9600238.
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Treem WR, Sokol RJ. Disorders of the mitochondria. Semin Liver Dis. 1998; 18(3):237-53. PMID: 9773424.
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Sokol RJ, McKim JM, Goff MC, Ruyle SZ, Devereaux MW, Han D, Packer L, Everson G. Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat. Gastroenterology. 1998 Jan; 114(1):164-74. PMID: 9428230.
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Colletti RB, Winter HS, Sokol RJ, Suchy FJ, Klish WJ, Durie PR. A position paper of the North American Society for Pediatric Gastroenterology and Nutrition. Pediatric gastroenterology Workforce Survey and future supply and demand. J Pediatr Gastroenterol Nutr. 1998 Jan; 26(1):106-15. PMID: 9443129.
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Narkewicz MR, Smith D, Gregory C, Lear JL, Osberg I, Sokol RJ. Effect of ursodeoxycholic acid therapy on hepatic function in children with intrahepatic cholestatic liver disease. J Pediatr Gastroenterol Nutr. 1998 Jan; 26(1):49-55. PMID: 9443120.
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Sokol RJ. Total parenteral nutrition-related liver disease. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 1997 Nov-Dec; 38(6):418-28. PMID: 9473812.
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Hoffenberg EJ, Rothenberg SS, Bensard D, Sondheimer JM, Sokol RJ. Outcome after exploratory laparoscopy for unexplained abdominal pain in childhood. Arch Pediatr Adolesc Med. 1997 Oct; 151(10):993-8. PMID: 9343009.
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Hoffenberg EJ, Deutsch J, Smith S, Sokol RJ. Circulating antioxidant concentrations in children with inflammatory bowel disease. Am J Clin Nutr. 1997 May; 65(5):1482-8. PMID: 9129480.
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Ferenci P, Gilliam TC, Gitlin JD, Packman S, Schilsky ML, Sokol RJ, Sternlieb I. An international symposium on Wilson's and Menkes' diseases. Hepatology. 1996 Oct; 24(4):952-8. PMID: 8855204.
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Price MR, Sartorelli KH, Karrer FM, Narkewicz MR, Sokol RJ, Lilly JR. Management of esophageal varices in children by endoscopic variceal ligation. J Pediatr Surg. 1996 Aug; 31(8):1056-9. PMID: 8863233.
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Riepenhoff-Talty M, Gouvea V, Evans MJ, Svensson L, Hoffenberg E, Sokol RJ, Uhnoo I, Greenberg SJ, Sch?kel K, Zhaori G, Fitzgerald J, Chong S, el-Yousef M, Nemeth A, Brown M, Piccoli D, Hyams J, Ruffin D, Rossi T. Detection of group C rotavirus in infants with extrahepatic biliary atresia. J Infect Dis. 1996 Jul; 174(1):8-15. PMID: 8656017.
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Easley DJ, Carter B, Rosenberg A, Wootton S, Martinez L, Sokol RJ. Congenital nonchylous ascites due to intestinal malrotation. J Pediatr Gastroenterol Nutr. 1996 Jul; 23(1):86-8. PMID: 8811529.
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Lepage G, Champagne J, Ronco N, Lamarre A, Osberg I, Sokol RJ, Roy CC. Supplementation with carotenoids corrects increased lipid peroxidation in children with cystic fibrosis. Am J Clin Nutr. 1996 Jul; 64(1):87-93. PMID: 8669420.
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Balistreri WF, Grand R, Hoofnagle JH, Suchy FJ, Ryckman FC, Perlmutter DH, Sokol RJ. Biliary atresia: current concepts and research directions. Summary of a symposium. Hepatology. 1996 Jun; 23(6):1682-92. PMID: 8675193.
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Du EZ, Wang SL, Kayden HJ, Sokol R, Curtiss LK, Davis RA. Translocation of apolipoprotein B across the endoplasmic reticulum is blocked in abetalipoproteinemia. J Lipid Res. 1996 Jun; 37(6):1309-15. PMID: 8808765.
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Sokol RJ. Expanding spectrum of mitochondrial disorders. J Pediatr. 1996 May; 128(5 Pt 1):597-9. PMID: 8627428.
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Karrer FM, Price MR, Bensard DD, Sokol RJ, Narkewicz MR, Smith DJ, Lilly JR. Long-term results with the Kasai operation for biliary atresia. Arch Surg. 1996 May; 131(5):493-6. PMID: 8624194.
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Sokol RJ, Taylor SF, Devereaux MW, Khandwala R, Sondheimer NJ, Shikes RH, Mierau G. Hepatic oxidant injury and glutathione depletion during total parenteral nutrition in weanling rats. Am J Physiol. 1996 Apr; 270(4 Pt 1):G691-700. PMID: 8928800.
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Sokol RJ, Hoffenberg EJ. Antioxidants in pediatric gastrointestinal disease. Pediatr Clin North Am. 1996 Apr; 43(2):471-88. PMID: 8614611.
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Sokol RJ. Antioxidant defenses in metal-induced liver damage. Semin Liver Dis. 1996 Feb; 16(1):39-46. PMID: 8723322.
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Sokol RJ, McKim JM, Devereaux MW. alpha-tocopherol ameliorates oxidant injury in isolated copper-overloaded rat hepatocytes. Pediatr Res. 1996 Feb; 39(2):259-63. PMID: 8825797.
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Alonso EM, Sokol RJ, Hart J, Tyson RW, Narkewicz MR, Whitington PF. Fulminant hepatitis associated with centrilobular hepatic necrosis in young children. J Pediatr. 1995 Dec; 127(6):888-94. PMID: 8523184.
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Narkewicz MR, Smith D, Silverman A, Vierling J, Sokol RJ. Clearance of chronic hepatitis B virus infection in young children after alpha interferon treatment. J Pediatr. 1995 Nov; 127(5):815-8. PMID: 7472844.
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Ramirez RO, Sokol RJ, Hays T, Silverman A. Familial occurrence of cavernous transformation of the portal vein. J Pediatr Gastroenterol Nutr. 1995 Oct; 21(3):313-8. PMID: 8523216.
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Sokol RJ, Winklhofer-Roob BM, Devereaux MW, McKim JM. Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids. Gastroenterology. 1995 Oct; 109(4):1249-56. PMID: 7557092.
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Sondheimer JM, Sokol RJ, Narkewicz MR, Tyson RW. Anastomotic ulceration: a late complication of ileocolonic anastomosis. J Pediatr. 1995 Aug; 127(2):225-30. PMID: 7636646.
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Hoffenberg EJ, Narkewicz MR, Sondheimer JM, Smith DJ, Silverman A, Sokol RJ. Outcome of syndromic paucity of interlobular bile ducts (Alagille syndrome) with onset of cholestasis in infancy. J Pediatr. 1995 Aug; 127(2):220-4. PMID: 7636645.
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Abdel-Rahman A, Parks JK, Devereaux MW, Sokol RJ, Parker WD, Rosenberg AA. Developmental changes in newborn lamb brain mitochondrial activity and postasphyxial lipid peroxidation. Proc Soc Exp Biol Med. 1995 Jun; 209(2):170-7. PMID: 7770468.
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Bayliss EA, Hambidge KM, Sokol RJ, Stewart B, Lilly JR. Hepatic concentrations of zinc, copper and manganese in infants with extrahepatic biliary atresia. J Trace Elem Med Biol. 1995 Mar; 9(1):40-3. PMID: 8846156.
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Ciotti M, Yeatman MT, Sokol RJ, Owens IS. Altered coding for a strictly conserved di-glycine in the major bilirubin UDP-glucuronosyltransferase of a Crigler-Najjar type I patient. J Biol Chem. 1995 Feb 17; 270(7):3284-91. PMID: 7852413.
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Ouahchi K, Arita M, Kayden H, Hentati F, Ben Hamida M, Sokol R, Arai H, Inoue K, Mandel JL, Koenig M. Ataxia with isolated vitamin E deficiency is caused by mutations in the alpha-tocopherol transfer protein. Nat Genet. 1995 Feb; 9(2):141-5. PMID: 7719340.
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Sokol RJ, Booker DJ, Stamps R, Windle JA. Autoimmune haemolysis and red cell autoantibodies with ABO blood group specificity. Haematologia (Budap). 1995; 26(3):121-9. PMID: 7797142.
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Sokol RJ. Fat-soluble vitamins and their importance in patients with cholestatic liver diseases. Gastroenterol Clin North Am. 1994 Dec; 23(4):673-705. PMID: 7698827.
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Sokol RJ, Twedt D, McKim JM, Devereaux MW, Karrer FM, Kam I, von Steigman G, Narkewicz MR, Bacon BR, Britton RS, et al. Oxidant injury to hepatic mitochondria in patients with Wilson's disease and Bedlington terriers with copper toxicosis. Gastroenterology. 1994 Dec; 107(6):1788-98. PMID: 7958693.
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Sokol RJ. At long last: an animal model of Wilson's disease. Hepatology. 1994 Aug; 20(2):533-5. PMID: 8045515.
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Occena RO, Taylor SF, Robinson CC, Sokol RJ. Association of cytomegalovirus with M?n?trier's disease in childhood: report of two new cases with a review of literature. J Pediatr Gastroenterol Nutr. 1993 Aug; 17(2):217-24. PMID: 8229553.
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Sokol RJ, Devereaux MW, O'Brien K, Khandwala RA, Loehr JP. Abnormal hepatic mitochondrial respiration and cytochrome C oxidase activity in rats with long-term copper overload. Gastroenterology. 1993 Jul; 105(1):178-87. PMID: 8390379.
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Sokol RJ, Butler-Simon N, Conner C, Heubi JE, Sinatra FR, Suchy FJ, Heyman MB, Perrault J, Rothbaum RJ, Levy J, et al. Multicenter trial of d-alpha-tocopheryl polyethylene glycol 1000 succinate for treatment of vitamin E deficiency in children with chronic cholestasis. Gastroenterology. 1993 Jun; 104(6):1727-35. PMID: 8500733.
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Sokol RJ, Devereaux M, Khandwala R, O'Brien K. Evidence for involvement of oxygen free radicals in bile acid toxicity to isolated rat hepatocytes. Hepatology. 1993 May; 17(5):869-81. PMID: 8387948.
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Traber MG, Sokol RJ, Kohlsch?tter A, Yokota T, Muller DP, Dufour R, Kayden HJ. Impaired discrimination between stereoisomers of alpha-tocopherol in patients with familial isolated vitamin E deficiency. J Lipid Res. 1993 Feb; 34(2):201-10. PMID: 8429255.
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Aanpreung P, Beckwith B, Galansky SH, Koyle MA, Sokol RJ. Association of paucity of interlobular bile ducts with prune belly syndrome. J Pediatr Gastroenterol Nutr. 1993 01; 16(1):81-6. PMID: 8094436.
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Hayward AR, Shriber M, Sokol R. Vitamin E supplementation reduces the incidence of diabetes but not insulitis in NOD mice. J Lab Clin Med. 1992 May; 119(5):503-7. PMID: 1583406.
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Bronstein MN, Sokol RJ, Abman SH, Chatfield BA, Hammond KB, Hambidge KM, Stall CD, Accurso FJ. Pancreatic insufficiency, growth, and nutrition in infants identified by newborn screening as having cystic fibrosis. J Pediatr. 1992 Apr; 120(4 Pt 1):533-40. PMID: 1552390.
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Hammond KB, Abman SH, Sokol RJ, Accurso FJ. Efficacy of statewide neonatal screening for cystic fibrosis by assay of trypsinogen concentrations. N Engl J Med. 1991 Sep 12; 325(11):769-74. PMID: 1870650.
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Sokol RJ, Devereaux M, Khandwala RA. Effect of dietary lipid and vitamin E on mitochondrial lipid peroxidation and hepatic injury in the bile duct-ligated rat. J Lipid Res. 1991 Aug; 32(8):1349-57. PMID: 1770317.
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Huang LS, Kayden H, Sokol RJ, Breslow JL. ApoB gene nonsense and splicing mutations in a compound heterozygote for familial hypobetalipoproteinemia. J Lipid Res. 1991 Aug; 32(8):1341-8. PMID: 1770316.
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Narkewicz MR, Sokol RJ, Beckwith B, Sondheimer J, Silverman A. Liver involvement in Alpers disease. J Pediatr. 1991 Aug; 119(2):260-7. PMID: 1861211.
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Sokol RJ, Johnson KE, Karrer FM, Narkewicz MR, Smith D, Kam I. Improvement of cyclosporin absorption in children after liver transplantation by means of water-soluble vitamin E. Lancet. 1991 Jul 27; 338(8761):212-4. PMID: 1676779.
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Sondheimer JM, Sokol RJ, Taylor SF, Silverman A, Zelasney B. Safety, efficacy, and tolerance of intestinal lavage in pediatric patients undergoing diagnostic colonoscopy. J Pediatr. 1991 Jul; 119(1 Pt 1):148-52. PMID: 2066847.
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Taylor SF, Sondheimer JM, Sokol RJ, Silverman A, Wilson HL. Noninfectious colitis associated with short gut syndrome in infants. J Pediatr. 1991 Jul; 119(1 Pt 1):24-8. PMID: 1676730.
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Sokol RJ, Reardon MC, Accurso FJ, Stall C, Narkewicz MR, Abman SH, Hammond KB. Fat-soluble vitamins in infants identified by cystic fibrosis newborn screening. Pediatr Pulmonol Suppl. 1991; 7:52-5. PMID: 1782131.
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Accurso FJ, Sokol RJ, Hammond KB, Abman SH. Early respiratory course in infants with cystic fibrosis: relevance to newborn screening. Pediatr Pulmonol Suppl. 1991; 7:42-5. PMID: 1782128.
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Sokol RJ, Devereaux M, Mierau GW, Hambidge KM, Shikes RH. Oxidant injury to hepatic mitochondrial lipids in rats with dietary copper overload. Modification by vitamin E deficiency. Gastroenterology. 1990 Oct; 99(4):1061-71. PMID: 2394327.
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Poh-Fitzpatrick MB, Zaider E, Sciales C, Sokol RJ, Tobin CE, Knobler E, Sadick NS, Silverberg M, Levy J. Cutaneous photosensitivity and coproporphyrin abnormalities in the Alagille syndrome. Gastroenterology. 1990 Sep; 99(3):831-5. PMID: 2379786.
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Sokol RJ, Stall C. Anthropometric evaluation of children with chronic liver disease. Am J Clin Nutr. 1990 Aug; 52(2):203-8. PMID: 2375285.
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Sokol RJ, Devereaux MW, Khandwala RA, Narkewicz MR, Sondheimer NJ. Effect of vitamin E on transport processes in isolated rat hepatocytes. J Pediatr Gastroenterol Nutr. 1990 Aug; 11(2):261-7. PMID: 2395066.
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Heubi JE, Sokol RJ, McGraw CA. Comparison of total serum lipids measured by two methods. J Pediatr Gastroenterol Nutr. 1990 May; 10(4):468-72. PMID: 2358979.
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Sokol RJ. Adoption of hepatitis B virus-infected foreign-born children. Pediatrics. 1990 May; 85(5):890-2. PMID: 2330255.
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Abman SH, Accurso FJ, Sokol RJ. Hypoalbuminemia in young infants with cystic fibrosis. J Pediatr. 1990 May; 116(5):840-1. PMID: 2329440.
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Traber MG, Sokol RJ, Burton GW, Ingold KU, Papas AM, Huffaker JE, Kayden HJ. Impaired ability of patients with familial isolated vitamin E deficiency to incorporate alpha-tocopherol into lipoproteins secreted by the liver. J Clin Invest. 1990 Feb; 85(2):397-407. PMID: 2298915.
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Sokol RJ. Vitamin E and neurologic deficits. Adv Pediatr. 1990; 37:119-48. PMID: 2176058.
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Sokol RJ, Reardon MC, Accurso FJ, Stall C, Narkewicz M, Abman SH, Hammond KB. Fat-soluble-vitamin status during the first year of life in infants with cystic fibrosis identified by screening of newborns. Am J Clin Nutr. 1989 Nov; 50(5):1064-71. PMID: 2816791.
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Broxson EH, Sokol RJ, Githens JH. Normal vitamin E status in sickle hemoglobinopathies in Colorado. Am J Clin Nutr. 1989 Sep; 50(3):497-503. PMID: 2773829.
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Sokol RJ. The coming of age of vitamin E. Hepatology. 1989 Apr; 9(4):649-53. PMID: 2647613.
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Hambidge KM, Sokol RJ, Fidanza SJ, Goodall MA. Plasma manganese concentrations in infants and children receiving parenteral nutrition. JPEN J Parenter Enteral Nutr. 1989 Mar-Apr; 13(2):168-71. PMID: 2496247.
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Sokol RJ, McCabe ER, Kotzer AM, Langendoerfer SI. Pitfalls in diagnosing galactosemia: false negative newborn screening following red blood cell transfusion. J Pediatr Gastroenterol Nutr. 1989 Feb; 8(2):266-8. PMID: 2540306.
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Sokol RJ, Kim YS, Hoofnagle JH, Heubi JE, Jones EA, Balistreri WF. Intestinal malabsorption of vitamin E in primary biliary cirrhosis. Gastroenterology. 1989 Feb; 96(2 Pt 1):479-86. PMID: 2910763.
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Sokol RJ, Butler-Simon N, Heubi JE, Iannaccone ST, McClung HJ, Accurso F, Hammond K, Heyman M, Sinatra F, Riely C, et al. Vitamin E deficiency neuropathy in children with fat malabsorption. Studies in cystic fibrosis and chronic cholestasis. Ann N Y Acad Sci. 1989; 570:156-69. PMID: 2629595.
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Narkewicz MR, Janoff EN, Sokol RJ, Levin MJ. Blastocystis hominis gastroenteritis in a hemophiliac with acquired immune deficiency syndrome. J Pediatr Gastroenterol Nutr. 1989 Jan; 8(1):125-8. PMID: 2732857.
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Sokol RJ. Vitamin E and neurologic function in man. Free Radic Biol Med. 1989; 6(2):189-207. PMID: 2651221.
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Sokol RJ, Devereaux MW, Traber MG, Shikes RH. Copper toxicity and lipid peroxidation in isolated rat hepatocytes: effect of vitamin E. Pediatr Res. 1989 Jan; 25(1):55-62. PMID: 2919118.
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Brown WR, Sokol RJ, Levin MJ, Silverman A, Tamaru T, Lilly JR, Hall RJ, Cheney M. Lack of correlation between infection with reovirus 3 and extrahepatic biliary atresia or neonatal hepatitis. J Pediatr. 1988 Oct; 113(4):670-6. PMID: 2845040.
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Sokol RJ, Kayden HJ, Bettis DB, Traber MG, Neville H, Ringel S, Wilson WB, Stumpf DA. Isolated vitamin E deficiency in the absence of fat malabsorption--familial and sporadic cases: characterization and investigation of causes. J Lab Clin Med. 1988 May; 111(5):548-59. PMID: 3361234.
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Sokol RJ. Vitamin E status in cholestasis. J Pediatr. 1988 Feb; 112(2):324-5. PMID: 3339514.
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Sokol RJ. Vitamin E deficiency and neurologic disease. Annu Rev Nutr. 1988; 8:351-73. PMID: 3060170.
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Sokol RJ, Butler-Simon NA, Bettis D, Smith DJ, Silverman A. Tocopheryl polyethylene glycol 1000 succinate therapy for vitamin E deficiency during chronic childhood cholestasis: neurologic outcome. J Pediatr. 1987 Dec; 111(6 Pt 1):830-6. PMID: 3681546.
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Sokol RJ, Heubi JE, Butler-Simon N, McClung HJ, Lilly JR, Silverman A. Treatment of vitamin E deficiency during chronic childhood cholestasis with oral d-alpha-tocopheryl polyethylene glycol-1000 succinate. Gastroenterology. 1987 Nov; 93(5):975-85. PMID: 3653646.
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Traber MG, Sokol RJ, Ringel SP, Neville HE, Thellman CA, Kayden HJ. Lack of tocopherol in peripheral nerves of vitamin E-deficient patients with peripheral neuropathy. N Engl J Med. 1987 Jul 30; 317(5):262-5. PMID: 3037372.
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Sokol RJ. Medical management of the infant or child with chronic liver disease. Semin Liver Dis. 1987 May; 7(2):155-67. PMID: 3112945.
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Stumpf DA, Sokol R, Bettis D, Neville H, Ringel S, Angelini C, Bell R. Friedreich's disease: V. Variant form with vitamin E deficiency and normal fat absorption. Neurology. 1987 Jan; 37(1):68-74. PMID: 3796840.
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Sokol RJ. Assessing vitamin E status in childhood cholestasis. J Pediatr Gastroenterol Nutr. 1987 Jan-Feb; 6(1):10-3. PMID: 3794924.
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Sokol RJ, Heubi JE, McGraw C, Balistreri WF. Correction of vitamin E deficiency in children with chronic cholestasis. II. Effect on gastrointestinal and hepatic function. Hepatology. 1986 Nov-Dec; 6(6):1263-9. PMID: 3793002.
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Iannaccone ST, Sokol RJ. Vitamin E deficiency in neuropathy of abetalipoproteinemia. Neurology. 1986 Jul; 36(7):1009. PMID: 3012411.
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Sokol RJ, Guggenheim MA, Iannaccone ST, Barkhaus PE, Miller C, Silverman A, Balistreri WF, Heubi JE. Improved neurologic function after long-term correction of vitamin E deficiency in children with chronic cholestasis. N Engl J Med. 1985 Dec 19; 313(25):1580-6. PMID: 4069170.
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Abman SH, Reardon MC, Accurso FJ, Hammond KB, Sokol RJ. Hypoalbuminemia at diagnosis as a marker for severe respiratory course in infants with cystic fibrosis identified by newborn screening. J Pediatr. 1985 Dec; 107(6):933-5. PMID: 3851839.
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Lilly JR, Sokol RJ. On the bile sludge syndrome or is total parenteral nutrition cholestasis a surgical disease? Pediatrics. 1985 Dec; 76(6):992-3. PMID: 3934640.
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Sokol RJ, Guggenheim MA, Heubi JE, Iannaccone ST, Butler-Simon N, Jackson V, Miller C, Cheney M, Balistreri WF, Silverman A. Frequency and clinical progression of the vitamin E deficiency neurologic disorder in children with prolonged neonatal cholestasis. Am J Dis Child. 1985 Dec; 139(12):1211-5. PMID: 4061425.
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Sokol RJ, Francis PD, Gold SH, Ford DM, Lum GM, Ambruso DR. Orthotopic liver transplantation for acute fulminant Wilson disease. J Pediatr. 1985 Oct; 107(4):549-52. PMID: 3900322.
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Sokol RJ, Balistreri WF, Hoofnagle JH, Jones EA. Vitamin E deficiency in adults with chronic liver disease. Am J Clin Nutr. 1985 Jan; 41(1):66-72. PMID: 3966426.
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Sokol RJ. Vitamin E toxicity. Pediatrics. 1984 Oct; 74(4):564-9. PMID: 6483527.
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Sokol RJ, Farrell MK, McAdams AJ. An unusual presentation of Wegener's granulomatosis mimicking inflammatory bowel disease. Gastroenterology. 1984 Aug; 87(2):426-32. PMID: 6735085.
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Sokol RJ, Heubi JE, Iannaccone ST, Bove KE, Balistreri WF. Vitamin E deficiency with normal serum vitamin E concentrations in children with chronic cholestasis. N Engl J Med. 1984 May 10; 310(19):1209-12. PMID: 6709026.
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Sokol RJ. Vitamin E deficiency in adults. Ann Intern Med. 1984 May; 100(5):769-70. PMID: 6712047.
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Sokol RJ, Farrell MK, Heubi JE, Tsang RC, Balistreri WF. Comparison of vitamin E and 25-hydroxyvitamin D absorption during childhood cholestasis. J Pediatr. 1983 Nov; 103(5):712-7. PMID: 6631597.
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Sokol RJ, Heubi JE, Iannaccone S, Bove KE, Balistreri WF. Mechanism causing vitamin E deficiency during chronic childhood cholestasis. Gastroenterology. 1983 Nov; 85(5):1172-82. PMID: 6618108.
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Sokol RJ, Heubi JE, Balistreri WF. Vitamin E deficiency in cholestatic liver disease. J Pediatr. 1983 Oct; 103(4):663-4. PMID: 6620033.
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Sokol RJ, Bove KE, Heubi JE, Iannaccone ST. Vitamin E deficiency during chronic childhood cholestasis: presence of sural nerve lesion prior to 2 1/2 years of age. J Pediatr. 1983 Aug; 103(2):197-204. PMID: 6308196.
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Sokol RJ, Heubi JE, Balistreri WF. Intrahepatic "cholestasis facies": is it specific for Alagille syndrome? J Pediatr. 1983 Aug; 103(2):205-8. PMID: 6875709.
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Lichtenstein PK, Heubi JE, Daugherty CC, Farrell MK, Sokol RJ, Rothbaum RJ, Suchy FJ, Balistreri WF. Grade I Reye's syndrome. A frequent cause of vomiting and liver dysfunction after varicella and upper-respiratory-tract infection. N Engl J Med. 1983 Jul 21; 309(3):133-9. PMID: 6866012.
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Sokol RJ, Heubi JE, Balistreri WF. Kasai procedure and vitamin E. Pediatrics. 1983 Apr; 71(4):668-9. PMID: 6835749.
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Sokol RJ, Iannaccone ST. Normal vitamin E status in spinal muscular atrophy. Ann Neurol. 1983 Mar; 13(3):328-30. PMID: 6847148.
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Oestreich AE, Sokol RJ, Suchy FJ, Heubi JE. Renal abnormalities in arteriohepatic dysplasia and nonsyndromic intrahepatic biliary hypoplasia. Ann Radiol (Paris). 1983 Feb-Mar; 26(2-3):203-9. PMID: 6881882.
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Sokol RJ, Lichtenstein PK, Farrell MK. Quinacrine hydrochloride-induced yellow discoloration of the skin in children. Pediatrics. 1982 Feb; 69(2):232-3. PMID: 7058099.
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Sokol RJ, Bowden RA. An erysipelas-like scalp cellulitis due to haemophilus influenzae type b. J Pediatr. 1980 Jan; 96(1):60-1. PMID: 6965310.
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1994 | 3 | 1995 | 11 | 1996 | 13 | 1997 | 3 | 1998 | 11 | 1999 | 9 | 2000 | 4 | 2001 | 7 | 2002 | 5 | 2003 | 9 | 2004 | 7 | 2005 | 15 | 2006 | 10 | 2007 | 16 | 2008 | 7 | 2009 | 6 | 2010 | 5 | 2011 | 8 | 2012 | 10 | 2013 | 12 | 2014 | 10 | 2015 | 10 | 2016 | 7 | 2017 | 4 | 2018 | 9 | 2019 | 6 | 2020 | 11 | 2021 | 11 | 2022 | 13 | 2023 | 13 | 2024 | 2 |
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