Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Matthew Frank

Concepts (260)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Microglia
26
2024
273
5.020
Why?
Glucocorticoids
15
2025
532
3.010
Why?
Hippocampus
30
2025
973
2.940
Why?
Stress, Psychological
15
2025
1151
2.600
Why?
HMGB1 Protein
8
2019
51
2.370
Why?
Lipopolysaccharides
19
2024
858
2.370
Why?
Inflammasomes
7
2023
144
2.160
Why?
Inflammation
24
2024
2884
1.790
Why?
Rats, Sprague-Dawley
36
2025
2525
1.730
Why?
Rats
48
2025
5585
1.700
Why?
Inflammation Mediators
7
2018
507
1.690
Why?
Encephalitis
6
2018
142
1.280
Why?
Brain
10
2024
2969
1.280
Why?
Stress, Physiological
4
2017
443
1.220
Why?
Mycobacterium
5
2024
101
1.150
Why?
Receptors, Immunologic
3
2019
209
1.070
Why?
Alarmins
4
2018
27
1.060
Why?
Spike Glycoprotein, Coronavirus
2
2024
129
0.930
Why?
Psychoneuroimmunology
1
2025
9
0.890
Why?
Anti-Inflammatory Agents
3
2023
478
0.890
Why?
Interleukin-1beta
12
2025
390
0.860
Why?
Prefrontal Cortex
3
2025
336
0.820
Why?
Animals
59
2025
38101
0.810
Why?
NLR Family, Pyrin Domain-Containing 3 Protein
9
2023
166
0.790
Why?
Probiotics
2
2025
61
0.740
Why?
Interleukin 1 Receptor Antagonist Protein
4
2012
253
0.710
Why?
Aging
10
2018
1973
0.700
Why?
Corticosterone
8
2025
241
0.630
Why?
Adaptation, Psychological
1
2025
719
0.610
Why?
Mycobacteriaceae
5
2023
34
0.600
Why?
Cytokines
12
2018
2069
0.600
Why?
Limbic System
1
2019
55
0.570
Why?
Cisterna Magna
4
2013
8
0.570
Why?
Escherichia coli Infections
4
2014
125
0.530
Why?
Intracellular Signaling Peptides and Proteins
1
2020
457
0.510
Why?
Neuroimmunomodulation
6
2019
67
0.510
Why?
Memory Disorders
5
2016
197
0.500
Why?
Male
51
2025
73010
0.470
Why?
Antigens, CD
2
2017
558
0.460
Why?
Receptors, Cytoplasmic and Nuclear
2
2015
209
0.450
Why?
Down-Regulation
1
2017
618
0.440
Why?
Central Nervous System
2
2018
282
0.440
Why?
Carrier Proteins
3
2015
729
0.430
Why?
Methamphetamine
1
2015
74
0.420
Why?
Receptors, Glucocorticoid
4
2025
129
0.410
Why?
Peripheral Nervous System Diseases
3
2010
134
0.390
Why?
Receptors, Interleukin-1
2
2012
211
0.370
Why?
Memory
4
2018
297
0.360
Why?
Rats, Inbred F344
9
2018
268
0.350
Why?
Neuroglia
3
2011
174
0.320
Why?
Signal Transduction
3
2025
5224
0.300
Why?
Mifepristone
4
2019
54
0.290
Why?
Disease Susceptibility
1
2011
344
0.290
Why?
Cytoskeletal Proteins
1
2009
157
0.290
Why?
Hypothalamo-Hypophyseal System
2
2025
199
0.280
Why?
Endotoxins
1
2009
217
0.280
Why?
Reverse Transcriptase Polymerase Chain Reaction
5
2012
979
0.270
Why?
RNA, Messenger
6
2020
2805
0.270
Why?
RNA, Antisense
1
2007
18
0.260
Why?
Spinal Cord
7
2023
382
0.250
Why?
Fibroblast Growth Factor 2
1
2007
94
0.240
Why?
Genes, MHC Class II
1
2006
77
0.230
Why?
Oxidative Stress
1
2013
1360
0.230
Why?
Nerve Tissue Proteins
1
2009
592
0.230
Why?
Centrifugation
1
2005
28
0.230
Why?
Histocompatibility Antigens
1
2006
102
0.230
Why?
Neuralgia
2
2023
140
0.230
Why?
Helplessness, Learned
1
2025
67
0.220
Why?
Interleukins
1
2006
248
0.210
Why?
Cell Separation
1
2005
306
0.210
Why?
History, 21st Century
1
2025
222
0.210
Why?
Pituitary-Adrenal System
1
2025
164
0.210
Why?
Diet, Western
1
2024
88
0.210
Why?
Immunity, Innate
4
2015
835
0.200
Why?
History, 20th Century
1
2025
328
0.200
Why?
Dependovirus
1
2024
78
0.190
Why?
Mentors
1
2025
217
0.190
Why?
Cell Culture Techniques
1
2005
375
0.190
Why?
Pathogen-Associated Molecular Pattern Molecules
1
2021
7
0.180
Why?
Cytomegalovirus Infections
1
2023
206
0.170
Why?
Interleukin-6
5
2023
780
0.170
Why?
Extinction, Psychological
1
2022
92
0.170
Why?
Substance-Related Disorders
1
2011
1103
0.170
Why?
Immunization
3
2018
375
0.170
Why?
Adrenal Cortex Hormones
1
2024
484
0.170
Why?
Weight Gain
1
2024
561
0.160
Why?
Phosphate-Binding Proteins
1
2020
6
0.160
Why?
Hot Temperature
2
2022
396
0.160
Why?
Toll-Like Receptor 2
2
2013
125
0.160
Why?
Vaccination
2
2020
1428
0.160
Why?
Enzyme-Linked Immunosorbent Assay
3
2012
849
0.160
Why?
Proteome
1
2025
513
0.160
Why?
Cerebrospinal Fluid Proteins
1
2020
9
0.150
Why?
Interleukin-10
4
2014
311
0.150
Why?
Caspase 1
1
2020
145
0.150
Why?
Depressive Disorder
1
2002
374
0.150
Why?
Hyperalgesia
3
2011
127
0.150
Why?
Toll-Like Receptor 4
2
2013
276
0.150
Why?
HEK293 Cells
1
2021
741
0.140
Why?
Interleukin-4
1
2020
207
0.140
Why?
Killer Cells, Natural
1
2002
481
0.140
Why?
Chronic Pain
1
2023
292
0.140
Why?
Rats, Inbred BN
4
2012
56
0.140
Why?
Receptors, Pattern Recognition
1
2018
11
0.140
Why?
Bacterial Vaccines
1
2018
63
0.130
Why?
Humans
15
2025
145783
0.130
Why?
Blood Proteins
1
2020
239
0.130
Why?
Macrophages
4
2023
1507
0.130
Why?
Genetic Therapy
3
2010
316
0.130
Why?
Up-Regulation
2
2013
848
0.130
Why?
Fear
4
2022
368
0.130
Why?
Circadian Rhythm
3
2018
513
0.130
Why?
Plasmids
2
2010
373
0.130
Why?
Proteomics
2
2025
1188
0.130
Why?
Cognition
2
2018
1271
0.120
Why?
Frontal Lobe
1
2018
160
0.120
Why?
Time Factors
6
2016
7134
0.120
Why?
Neurogenic Inflammation
1
2016
2
0.120
Why?
Amygdala
1
2017
200
0.120
Why?
Lipid Metabolism
1
2020
529
0.120
Why?
Drug Synergism
2
2013
354
0.110
Why?
Adrenalectomy
2
2014
68
0.110
Why?
Affect
1
2018
321
0.110
Why?
Illness Behavior
1
2014
9
0.110
Why?
Real-Time Polymerase Chain Reaction
2
2013
337
0.110
Why?
Brain Mapping
1
2018
542
0.110
Why?
Diet, High-Fat
1
2016
266
0.110
Why?
Ventral Tegmental Area
1
2015
63
0.110
Why?
Spleen
2
2014
508
0.100
Why?
Anxiety
2
2020
1122
0.100
Why?
Behavior, Animal
3
2012
520
0.100
Why?
Circadian Clocks
1
2014
59
0.100
Why?
Laparotomy
2
2011
113
0.100
Why?
Nucleus Accumbens
1
2015
135
0.100
Why?
Corpus Striatum
1
2015
179
0.100
Why?
CD11b Antigen
2
2010
60
0.100
Why?
Liver
2
2014
1899
0.100
Why?
Injections, Spinal
6
2010
120
0.100
Why?
Physical Conditioning, Animal
2
2014
242
0.100
Why?
Injections
2
2013
199
0.090
Why?
Sex Characteristics
1
2018
789
0.090
Why?
Cognitive Dysfunction
1
2018
468
0.090
Why?
Pain
4
2011
791
0.090
Why?
Oxidation-Reduction
1
2015
1069
0.090
Why?
Interleukin-1
2
2007
961
0.090
Why?
DNA
2
2010
1437
0.090
Why?
Receptor, Serotonin, 5-HT1A
1
2011
37
0.090
Why?
Gram-Negative Bacterial Infections
1
2011
49
0.080
Why?
Dose-Response Relationship, Drug
3
2011
2028
0.080
Why?
Raphe Nuclei
1
2011
111
0.080
Why?
HIV Envelope Protein gp120
2
2010
55
0.080
Why?
Immune System
1
2012
180
0.080
Why?
Fever
1
2011
320
0.080
Why?
Transcription Factors
1
2018
1736
0.080
Why?
Genes, fos
1
2009
36
0.080
Why?
Gene Expression Regulation
2
2010
2601
0.070
Why?
Microfilament Proteins
1
2010
135
0.070
Why?
Hyperesthesia
2
2006
6
0.070
Why?
Calcium-Binding Proteins
1
2010
221
0.070
Why?
Gene Transfer Techniques
1
2010
187
0.070
Why?
Histocompatibility Antigens Class II
1
2010
364
0.070
Why?
Cognition Disorders
1
2012
544
0.070
Why?
Chemical and Drug Induced Liver Injury
1
2009
138
0.070
Why?
Hydrocortisone
1
2009
298
0.060
Why?
Tumor Necrosis Factor-alpha
2
2014
1217
0.060
Why?
Pain Threshold
1
2007
72
0.060
Why?
Neuronal Plasticity
1
2009
305
0.060
Why?
Foreign-Body Reaction
1
2007
34
0.060
Why?
Cells, Cultured
4
2018
4151
0.060
Why?
Catheterization
1
2007
184
0.060
Why?
Immunohistochemistry
2
2010
1723
0.060
Why?
DNA, Complementary
1
2006
273
0.060
Why?
Minocycline
1
2005
23
0.060
Why?
DNA Primers
1
2006
505
0.050
Why?
Disease Models, Animal
2
2013
4568
0.050
Why?
Chemokines, CX3C
1
2004
10
0.050
Why?
Adjuvants, Pharmaceutic
1
2023
15
0.050
Why?
Intra-Abdominal Fat
1
2024
101
0.050
Why?
Constriction
1
2023
45
0.050
Why?
Transduction, Genetic
1
2024
132
0.050
Why?
Transgenes
1
2024
190
0.050
Why?
Morphine
1
2004
169
0.050
Why?
Leptin
1
2024
248
0.050
Why?
Animals, Genetically Modified
1
2024
247
0.050
Why?
Genetic Vectors
1
2024
335
0.050
Why?
Electroshock
2
2013
146
0.050
Why?
Administration, Oral
1
2025
867
0.040
Why?
Adjuvants, Immunologic
1
2023
244
0.040
Why?
Tissue Distribution
2
2016
335
0.040
Why?
Gene Expression Regulation, Developmental
1
2006
910
0.040
Why?
Age of Onset
1
2002
557
0.040
Why?
Psychiatric Status Rating Scales
1
2002
533
0.040
Why?
Adiposity
1
2024
532
0.040
Why?
Postoperative Complications
1
2012
2977
0.040
Why?
Gene Expression Profiling
1
2006
1777
0.040
Why?
Escherichia coli
2
2016
835
0.030
Why?
Flow Cytometry
1
2002
1165
0.030
Why?
Optical Fibers
1
2018
17
0.030
Why?
Pain Measurement
2
2011
562
0.030
Why?
Vaccines, Inactivated
1
2018
70
0.030
Why?
Membrane Proteins
1
2004
1166
0.030
Why?
Immunoassay
1
2018
109
0.030
Why?
Host-Pathogen Interactions
2
2011
361
0.030
Why?
Neurons
1
2006
1652
0.030
Why?
Memory, Long-Term
1
2016
12
0.030
Why?
Mice
2
2024
18355
0.030
Why?
Hormone Antagonists
1
2016
33
0.030
Why?
Gastrointestinal Microbiome
1
2024
768
0.030
Why?
DNA-Binding Proteins
1
2023
1482
0.030
Why?
Antibodies
1
2018
397
0.030
Why?
Random Allocation
1
2016
365
0.030
Why?
Analgesics, Opioid
1
2004
1154
0.030
Why?
Lipids
1
2020
707
0.030
Why?
Rats, Wistar
1
2016
450
0.030
Why?
11-beta-Hydroxysteroid Dehydrogenase Type 1
1
2014
10
0.030
Why?
Phenotype
1
2002
3170
0.030
Why?
Catalysis
1
2014
305
0.030
Why?
Proteins
1
2020
1023
0.020
Why?
Mice, Inbred C57BL
1
2024
5992
0.020
Why?
Conditioning, Classical
1
2014
119
0.020
Why?
Alzheimer Disease
1
2020
630
0.020
Why?
Injections, Intraventricular
1
2012
59
0.020
Why?
Cell Line
1
2018
2823
0.020
Why?
Phosphatidylcholines
1
2013
131
0.020
Why?
Macrophages, Peritoneal
1
2011
89
0.020
Why?
Physical Stimulation
1
2011
69
0.020
Why?
Obesity
1
2024
3118
0.020
Why?
Polyglycolic Acid
1
2010
44
0.020
Why?
Glial Fibrillary Acidic Protein
1
2010
122
0.020
Why?
Cell Line, Tumor
1
2018
3551
0.020
Why?
Serotonin
1
2011
298
0.020
Why?
Female
3
2023
79045
0.020
Why?
Amnesia, Anterograde
1
2008
7
0.020
Why?
Particle Size
1
2010
381
0.020
Why?
Lactic Acid
1
2010
295
0.020
Why?
Exercise Test
1
2011
630
0.020
Why?
Parietal Lobe
1
2008
61
0.020
Why?
Action Potentials
1
2011
502
0.020
Why?
Hypothalamus
1
2008
163
0.020
Why?
Cyclooxygenase 1
1
2007
27
0.020
Why?
Microinjections
1
2006
92
0.020
Why?
Evidence-Based Medicine
1
2010
740
0.020
Why?
Ligation
1
2006
91
0.020
Why?
Sciatic Nerve
1
2006
63
0.010
Why?
Cyclooxygenase 2
1
2007
167
0.010
Why?
Nitric Oxide
1
2010
892
0.010
Why?
CX3C Chemokine Receptor 1
1
2004
19
0.010
Why?
Receptors, HIV
1
2004
22
0.010
Why?
Chemokine CX3CL1
1
2004
25
0.010
Why?
Stress, Mechanical
1
2007
494
0.010
Why?
Receptors, Cytokine
1
2004
36
0.010
Why?
Drug Administration Schedule
1
2006
782
0.010
Why?
Sialoglycoproteins
1
2004
157
0.010
Why?
Drug Tolerance
1
2004
99
0.010
Why?
Analysis of Variance
1
2007
1300
0.010
Why?
Neuroprotective Agents
1
2005
148
0.010
Why?
Nanoparticles
1
2010
517
0.010
Why?
Pain Management
1
2004
411
0.010
Why?
Middle Aged
1
2002
36309
0.010
Why?
Adult
1
2002
40881
0.010
Why?
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