 Gene Transfer Techniques
"Gene Transfer Techniques" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The introduction of functional (usually cloned) GENES into cells. A variety of techniques and naturally occurring processes are used for the gene transfer such as cell hybridization, LIPOSOMES or microcell-mediated gene transfer, ELECTROPORATION, chromosome-mediated gene transfer, TRANSFECTION, and GENETIC TRANSDUCTION. Gene transfer may result in genetically transformed cells and individual organisms.
| Descriptor ID |
D018014
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| MeSH Number(s) |
E05.393.350
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| Concept/Terms |
Gene Transfer Techniques- Gene Transfer Techniques
- Technique, Gene Transfer
- Techniques, Gene Transfer
- Transfer Technique, Gene
- Transfer Techniques, Gene
- Transgenesis
- Gene Transfer Technique
Gene Delivery Systems- Gene Delivery Systems
- Delivery System, Gene
- Delivery Systems, Gene
- Gene Delivery System
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Below are MeSH descriptors whose meaning is more general than "Gene Transfer Techniques".
Below are MeSH descriptors whose meaning is more specific than "Gene Transfer Techniques".
This graph shows the total number of publications written about "Gene Transfer Techniques" by people in this website by year, and whether "Gene Transfer Techniques" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 2 | 3 | 5 | | 1997 | 4 | 1 | 5 | | 1998 | 1 | 5 | 6 | | 1999 | 3 | 2 | 5 | | 2000 | 4 | 2 | 6 | | 2001 | 3 | 3 | 6 | | 2002 | 4 | 2 | 6 | | 2003 | 3 | 2 | 5 | | 2004 | 1 | 8 | 9 | | 2005 | 3 | 4 | 7 | | 2006 | 1 | 3 | 4 | | 2007 | 3 | 5 | 8 | | 2008 | 0 | 3 | 3 | | 2009 | 3 | 1 | 4 | | 2010 | 2 | 1 | 3 | | 2011 | 5 | 6 | 11 | | 2012 | 2 | 1 | 3 | | 2013 | 4 | 2 | 6 | | 2014 | 4 | 3 | 7 | | 2015 | 1 | 0 | 1 | | 2016 | 2 | 3 | 5 | | 2017 | 1 | 2 | 3 | | 2018 | 1 | 3 | 4 | | 2019 | 3 | 0 | 3 | | 2020 | 2 | 2 | 4 | | 2021 | 2 | 3 | 5 | | 2023 | 1 | 0 | 1 | | 2024 | 4 | 2 | 6 | | 2025 | 3 | 2 | 5 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "Gene Transfer Techniques" by people in Profiles.
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Han X, Xu Y, Ricciardi AS, Xu J, Xiang Y, Palanki R, Chowdhary V, Xue L, Gong N, Alameh MG, Peranteau WH, Wilson JM, Reker D, Weissman D, Mitchell MJ. Plug-and-play assembly of biodegradable ionizable lipids for potent mRNA delivery and gene editing in vivo. Proc Natl Acad Sci U S A. 2026 Jun 02; 123(22):e2528144123.
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Gong N, Kim D, Alameh MG, El-Mayta R, Han EL, Dwivedi G, Palanki R, Shi Q, Han X, Xue L, Xu J, Meng Z, Luo T, Figueroa-Espada CG, Weissman D, Li J, Mitchell MJ. Mannich reaction-based combinatorial libraries identify antioxidant ionizable lipids for mRNA delivery with reduced immunogenicity. Nat Biomed Eng. 2025 Dec; 9(12):2181-2195.
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Sekar RP, Lawson JL, McGrath C, Wheeler G, Moreau G, Johansen CG, Farnsworth NL, Kumar R. Tuning DLVO Interactions Alters Polymer-Mediated pDNA Delivery in a Cell Type-Dependent Manner. Langmuir. 2025 Jul 15; 41(27):17426-17438.
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Wu F, Li N, Xiao Y, Palanki R, Yamagata H, Mitchell MJ, Han X. Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components. Small Methods. 2026 Jan; 10(2):e2401632.
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Padilla MS, Mrksich K, Wang Y, Haley RM, Li JJ, Han EL, El-Mayta R, Kim EH, Dias S, Gong N, Teerdhala SV, Han X, Chowdhary V, Xue L, Siddiqui Z, Yamagata HM, Kim D, Yoon IC, Wilson JM, Radhakrishnan R, Mitchell MJ. Branched endosomal disruptor (BEND) lipids mediate delivery of mRNA and CRISPR-Cas9 ribonucleoprotein complex for hepatic gene editing and T cell engineering. Nat Commun. 2025 Jan 24; 16(1):996.
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Xue L, Xiong X, Zhao G, Molina-Arocho W, Palanki R, Xiao Z, Han X, Yoon IC, Figueroa-Espada CG, Xu J, Gong N, Shi Q, Chen Q, Alameh MG, Vaughan AE, Haldar M, Wang K, Weissman D, Mitchell MJ. Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen. J Am Chem Soc. 2025 Jan 15; 147(2):1542-1552.
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Nunes LGA, Rosario FJ, Urschitz J. In vivo placental gene modulation via sonoporation. Placenta. 2025 Jun 13; 166:109-116.
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Xue L, Zhao G, Gong N, Han X, Shepherd SJ, Xiong X, Xiao Z, Palanki R, Xu J, Swingle KL, Warzecha CC, El-Mayta R, Chowdhary V, Yoon IC, Xu J, Cui J, Shi Y, Alameh MG, Wang K, Wang L, Pochan DJ, Weissman D, Vaughan AE, Wilson JM, Mitchell MJ. Combinatorial design of siloxane-incorporated lipid nanoparticles augments intracellular processing for tissue-specific mRNA therapeutic delivery. Nat Nanotechnol. 2025 Jan; 20(1):132-143.
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O'Donnell M, Fontaine A, Caldwell J, Weir R. Direct dorsal root ganglia (DRG) injection in mice for analysis of adeno-associated viral (AAV) gene transfer to peripheral somatosensory neurons. J Neurosci Methods. 2024 Nov; 411:110268.
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Han X, Alameh MG, Gong N, Xue L, Ghattas M, Bojja G, Xu J, Zhao G, Warzecha CC, Padilla MS, El-Mayta R, Dwivedi G, Xu Y, Vaughan AE, Wilson JM, Weissman D, Mitchell MJ. Fast and facile synthesis of amidine-incorporated degradable lipids for versatile mRNA delivery in vivo. Nat Chem. 2024 Oct; 16(10):1687-1697.
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