 Ventral Tegmental Area
"Ventral Tegmental Area" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A region in the MESENCEPHALON which is dorsomedial to the SUBSTANTIA NIGRA and ventral to the RED NUCLEUS. The mesocortical and mesolimbic dopaminergic systems originate here, including an important projection to the NUCLEUS ACCUMBENS. Overactivity of the cells in this area has been suspected to contribute to the positive symptoms of SCHIZOPHRENIA.
| Descriptor ID |
D017557
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| MeSH Number(s) |
A08.186.211.132.659.413.875.820
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| Concept/Terms |
Ventral Tegmental Area- Ventral Tegmental Area
- Tegmental Area, Ventral
- Ventral Tegmental Area of Tsai
- Area Tegmentalis Ventralis
- Area Tegmentalis Ventrali
- Tegmentalis Ventrali, Area
- Tegmentalis Ventralis, Area
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Below are MeSH descriptors whose meaning is more general than "Ventral Tegmental Area".
Below are MeSH descriptors whose meaning is more specific than "Ventral Tegmental Area".
This graph shows the total number of publications written about "Ventral Tegmental Area" by people in this website by year, and whether "Ventral Tegmental Area" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 1 | 0 | 1 | | 2009 | 3 | 0 | 3 | | 2010 | 0 | 1 | 1 | | 2012 | 3 | 0 | 3 | | 2013 | 1 | 1 | 2 | | 2014 | 2 | 0 | 2 | | 2015 | 0 | 4 | 4 | | 2016 | 2 | 2 | 4 | | 2017 | 3 | 0 | 3 | | 2018 | 2 | 1 | 3 | | 2019 | 2 | 0 | 2 | | 2020 | 1 | 0 | 1 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 1 | 2 | | 2023 | 2 | 1 | 3 |
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Below are the most recent publications written about "Ventral Tegmental Area" by people in Profiles.
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Barcomb K, Ford CP. Alterations in neurotransmitter co-release in Parkinson's disease. Exp Neurol. 2023 12; 370:114562.
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McGovern DJ, Polter AM, Pr?vost ED, Ly A, McNulty CJ, Rubinstein B, Root DH. Ventral tegmental area glutamate neurons establish a mu-opioid receptor gated circuit to mesolimbic dopamine neurons and regulate opioid-seeking behavior. Neuropsychopharmacology. 2023 12; 48(13):1889-1900.
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Bortz DM, Feistritzer CM, Grace AA. Medial Prefrontal Cortex to Medial Septum Pathway Activation Improves Cognitive Flexibility in Rats. Int J Neuropsychopharmacol. 2023 Jun 23; 26(6):426-437.
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McGovern DJ, Ly A, Ecton KL, Huynh DT, Pr?vost ED, Gonzalez SC, McNulty CJ, Rau AR, Hentges ST, Daigle TL, Tasic B, Baratta MV, Root DH. Ventral tegmental area glutamate neurons mediate nonassociative consequences of stress. Mol Psychiatry. 2024 Jun; 29(6):1671-1682.
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Bortz DM, Feistritzer CM, Power CC, Grace AA. Medial septum activation improves strategy switching once strategies are well-learned via bidirectional regulation of dopamine neuron population activity. Neuropsychopharmacology. 2022 11; 47(12):2090-2100.
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McGovern DJ, Polter AM, Root DH. Neurochemical Signaling of Reward and Aversion to Ventral Tegmental Area Glutamate Neurons. J Neurosci. 2021 06 23; 41(25):5471-5486.
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Root DH, Barker DJ, Estrin DJ, Miranda-Barrientos JA, Liu B, Zhang S, Wang HL, Vautier F, Ramakrishnan C, Kim YS, Fenno L, Deisseroth K, Morales M. Distinct Signaling by Ventral Tegmental Area Glutamate, GABA, and Combinatorial Glutamate-GABA Neurons in Motivated Behavior. Cell Rep. 2020 09 01; 32(9):108094.
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Wang X, Northcutt AL, Cochran TA, Zhang X, Fabisiak TJ, Haas ME, Amat J, Li H, Rice KC, Maier SF, Bachtell RK, Hutchinson MR, Watkins LR. Methamphetamine Activates Toll-Like Receptor 4 to Induce Central Immune Signaling within the Ventral Tegmental Area and Contributes to Extracellular Dopamine Increase in the Nucleus Accumbens Shell. ACS Chem Neurosci. 2019 08 21; 10(8):3622-3634.
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Bortz DM, Gazo KL, Grace AA. The medial septum enhances reversal learning via opposing actions on ventral tegmental area and substantia nigra dopamine neurons. Neuropsychopharmacology. 2019 12; 44(13):2186-2194.
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Coutens B, Mouledous L, Stella M, Rampon C, Lapeyre-Mestre M, Roussin A, Guiard BP, Jouanjus E. Lack of correlation between the activity of the mesolimbic dopaminergic system and the rewarding properties of pregabalin in mouse. Psychopharmacology (Berl). 2019 Jul; 236(7):2069-2082.
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