 Chemokine CX3CL1
"Chemokine CX3CL1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A CX3C chemokine that is a transmembrane protein found on the surface of cells. The soluble form of chemokine CX3CL1 can be released from cell surface by proteolysis and act as a chemoattractant that may be involved in the extravasation of leukocytes into inflamed tissues. The membrane form of the protein may also play a role in cell adhesion.
| Descriptor ID |
D054428
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| MeSH Number(s) |
D12.644.276.374.200.130.500 D12.776.467.374.200.130.500 D12.776.543.193 D23.125.300.130.500 D23.469.200.130.500 D23.529.374.200.130.500
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| Concept/Terms |
Chemokine CX3CL1- Chemokine CX3CL1
- CX3CL1, Chemokine
- CX3CL1 Chemokine
- Chemokine, CX3CL1
- Neurotactin
- Chemokine (C-X3-C Motif) Ligand 1
- Fractalkine
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Below are MeSH descriptors whose meaning is more general than "Chemokine CX3CL1".
Below are MeSH descriptors whose meaning is more specific than "Chemokine CX3CL1".
This graph shows the total number of publications written about "Chemokine CX3CL1" by people in this website by year, and whether "Chemokine CX3CL1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 3 | 3 | | 2005 | 0 | 1 | 1 | | 2007 | 2 | 0 | 2 | | 2008 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chemokine CX3CL1" by people in Profiles.
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Mikosz A, Ni K, Gally F, Pratte KA, Winfree S, Lin Q, Echelman I, Wetmore B, Cao D, Justice MJ, Sandhaus RA, Maier L, Strange C, Bowler RP, Petrache I, Serban KA. Alpha-1 antitrypsin inhibits fractalkine-mediated monocyte-lung endothelial cell interactions. Am J Physiol Lung Cell Mol Physiol. 2023 12 01; 325(6):L711-L725.
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Mendiola AS, Church KA, Cardona SM, Vanegas D, Garcia SA, Macklin W, Lira SA, Ransohoff RM, Kokovay E, Lin CA, Cardona AE. Defective fractalkine-CX3CR1 signaling aggravates neuroinflammation and affects recovery from cuprizone-induced demyelination. J Neurochem. 2022 09; 162(5):430-443.
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Greiffo FR, Viteri-Alvarez V, Frankenberger M, Dietel D, Ortega-Gomez A, Lee JS, Hilgendorff A, Behr J, Soehnlein O, Eickelberg O, Fernandez IE. CX3CR1-fractalkine axis drives kinetic changes of monocytes in fibrotic interstitial lung diseases. Eur Respir J. 2020 02; 55(2).
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Lee DW, Faubel S, Edelstein CL. Cytokines in acute kidney injury (AKI). Clin Nephrol. 2011 Sep; 76(3):165-73.
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Hutchinson MR, Coats BD, Lewis SS, Zhang Y, Sprunger DB, Rezvani N, Baker EM, Jekich BM, Wieseler JL, Somogyi AA, Martin D, Poole S, Judd CM, Maier SF, Watkins LR. Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun. 2008 Nov; 22(8):1178-89.
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Meditz AL, Schlichtemeier R, Folkvord JM, Givens M, Lesh KC, Ray MG, McCarter MD, Connick E. SDF-1alpha is a potent inducer of HIV-1-Specific CD8+ T-cell chemotaxis, but migration of CD8+ T cells is impaired at high viral loads. AIDS Res Hum Retroviruses. 2008 Jul; 24(7):977-85.
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Oh DJ, Dursun B, He Z, Lu L, Hoke TS, Ljubanovic D, Faubel S, Edelstein CL. Fractalkine receptor (CX3CR1) inhibition is protective against ischemic acute renal failure in mice. Am J Physiol Renal Physiol. 2008 Jan; 294(1):F264-71.
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Lu LH, Oh DJ, Dursun B, He Z, Hoke TS, Faubel S, Edelstein CL. Increased macrophage infiltration and fractalkine expression in cisplatin-induced acute renal failure in mice. J Pharmacol Exp Ther. 2008 Jan; 324(1):111-7.
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Milligan E, Zapata V, Schoeniger D, Chacur M, Green P, Poole S, Martin D, Maier SF, Watkins LR. An initial investigation of spinal mechanisms underlying pain enhancement induced by fractalkine, a neuronally released chemokine. Eur J Neurosci. 2005 Dec; 22(11):2775-82.
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Milligan ED, Zapata V, Chacur M, Schoeniger D, Biedenkapp J, O'Connor KA, Verge GM, Chapman G, Green P, Foster AC, Naeve GS, Maier SF, Watkins LR. Evidence that exogenous and endogenous fractalkine can induce spinal nociceptive facilitation in rats. Eur J Neurosci. 2004 Nov; 20(9):2294-302.
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