 Interleukin-10
"Interleukin-10" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cytokine produced by a variety of cell types, including T-LYMPHOCYTES; MONOCYTES; DENDRITIC CELLS; and EPITHELIAL CELLS that exerts a variety of effects on immunoregulation and INFLAMMATION. Interleukin-10 combines with itself to form a homodimeric molecule that is the biologically active form of the protein.
| Descriptor ID |
D016753
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| MeSH Number(s) |
D12.644.276.374.465.510 D12.776.467.374.465.510 D23.529.374.465.510
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| Concept/Terms |
Interleukin-10- Interleukin-10
- Interleukin 10
- IL10
- IL-10
- CSIF-10
- Cytokine Synthesis Inhibitory Factor
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Below are MeSH descriptors whose meaning is more general than "Interleukin-10".
Below are MeSH descriptors whose meaning is more specific than "Interleukin-10".
This graph shows the total number of publications written about "Interleukin-10" by people in this website by year, and whether "Interleukin-10" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 1 | 2 | | 1995 | 5 | 2 | 7 | | 1996 | 2 | 0 | 2 | | 1997 | 1 | 1 | 2 | | 1998 | 1 | 4 | 5 | | 1999 | 3 | 2 | 5 | | 2000 | 4 | 0 | 4 | | 2001 | 3 | 0 | 3 | | 2002 | 1 | 3 | 4 | | 2003 | 1 | 5 | 6 | | 2004 | 2 | 5 | 7 | | 2005 | 7 | 4 | 11 | | 2006 | 6 | 8 | 14 | | 2007 | 2 | 3 | 5 | | 2008 | 4 | 7 | 11 | | 2009 | 2 | 5 | 7 | | 2010 | 6 | 5 | 11 | | 2011 | 1 | 7 | 8 | | 2012 | 4 | 8 | 12 | | 2013 | 3 | 7 | 10 | | 2014 | 5 | 6 | 11 | | 2015 | 4 | 3 | 7 | | 2016 | 7 | 3 | 10 | | 2017 | 3 | 3 | 6 | | 2018 | 3 | 5 | 8 | | 2019 | 3 | 2 | 5 | | 2020 | 2 | 0 | 2 | | 2021 | 3 | 1 | 4 | | 2022 | 3 | 5 | 8 | | 2023 | 0 | 5 | 5 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interleukin-10" by people in Profiles.
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Horn KJ, Fulte S, Yang M, Lorenz BP, Clark SE. Neutrophil responsiveness to IL-10 impairs clearance of Streptococcus pneumoniae from the lungs. J Leukoc Biol. 2024 01 05; 115(1):4-15.
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Foley KE, Winder Z, Sudduth TL, Martin BJ, Nelson PT, Jicha GA, Harp JP, Weekman EM, Wilcock DM. Alzheimer's disease and inflammatory biomarkers positively correlate in plasma in the UK-ADRC cohort. Alzheimers Dement. 2024 Feb; 20(2):1374-1386.
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Epeldegui M, Chang D, Lee J, Magpantay LI, Borok M, Bukuru A, Busakhala N, Godfrey C, Hosseinipour MC, Kang M, Kanyama C, Langat D, Mngqibisa R, Mwelase N, Nyirenda M, Samaneka W, Hoagland B, Campbell TB, Mart?nez-Maza O, Krown SE. Predictive Value of Serum Biomarkers for Response of Limited-Stage AIDS-Associated Kaposi Sarcoma to Antiretroviral Therapy With or Without Concomitant Chemotherapy in Resource-Limited Settings. J Acquir Immune Defic Syndr. 2023 10 01; 94(2):165-173.
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Mitsui Y, Suzuki T, Kuniyoshi K, Inamo J, Yamaguchi K, Komuro M, Watanabe J, Edamoto M, Li S, Kouno T, Oba S, Hosoya T, Masuhiro K, Naito Y, Koyama S, Sakaguchi N, Standley DM, Shin JW, Akira S, Yasuda S, Miyazaki Y, Kochi Y, Kumanogoh A, Okamoto T, Satoh T. Expression of the readthrough transcript CiDRE in alveolar macrophages boosts SARS-CoV-2 susceptibility and promotes COVID-19 severity. Immunity. 2023 08 08; 56(8):1939-1954.e12.
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Plecit?-Hlavat? L, Br?zdov? A, Krivonoskov? M, Hu CJ, Phang T, Tauber J, Li M, Zhang H, Hoetzenecker K, Crnkovic S, Kwapiszewska G, Stenmark KR. Microenvironmental regulation of T-cells in pulmonary hypertension. Front Immunol. 2023; 14:1223122.
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Clements MA, Kwilasz AJ, Litwiler ST, Sents Z, Woodall BJ, Hayashida K, Watkins LR. Intrathecal non-viral interleukin-10 gene therapy ameliorates neuropathic pain as measured by both classical static allodynia and a novel supra-spinally mediated pain assay, the Two-Arm Rodent Somatosensory (TARS) task. Brain Behav Immun. 2023 07; 111:177-185.
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Eskandari SK, Gaya da Costa M, Faria B, Petr V, Azzi JR, Berger SP, Seelen MAJ, Damman J, Poppelaars F. An interleukin 6-based genetic risk score strengthened with interleukin 10 polymorphisms associated with long-term kidney allograft outcomes. Am J Transplant. 2022 12; 22 Suppl 4:45-57.
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Erlandson G, Magzamen S, Sharp JL, Mitra S, Jones K, Poole JA, Bradford M, Nonnenmann M, Reynolds SJ, Schaeffer JW. Preliminary investigation of a hypertonic saline nasal rinse as a hygienic intervention in dairy workers. J Occup Environ Hyg. 2023 01; 20(1):14-22.
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Jalbert E, Ghosh T, Smith C, Amaral FR, Mussi-Pinhata MM, Weinberg A. Impaired functionality of antigen presenting cells in HIV- exposed uninfected infants in the first six months of life. Front Immunol. 2022; 13:960313.
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Rocker AJ, Cavasin M, Johnson NR, Shandas R, Park D. Sulfonated Thermoresponsive Injectable Gel for Sequential Release of Therapeutic Proteins to Protect Cardiac Function after Myocardial Infarction. ACS Biomater Sci Eng. 2022 09 12; 8(9):3883-3898.
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