 Receptor, Serotonin, 5-HT1A
"Receptor, Serotonin, 5-HT1A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found distributed through the CENTRAL NERVOUS SYSTEM where they are involved in neuroendocrine regulation of ACTH secretion. The fact that this serotonin receptor subtype is particularly sensitive to SEROTONIN RECEPTOR AGONISTS such as BUSPIRONE suggests its role in the modulation of ANXIETY and DEPRESSION.
| Descriptor ID |
D044282
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| MeSH Number(s) |
D12.776.543.750.670.800.100.100 D12.776.543.750.695.800.100.100 D12.776.543.750.720.850.100.100
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| Concept/Terms |
Receptor, Serotonin, 5-HT1A- Receptor, Serotonin, 5-HT1A
- 5-HT1A Receptor
- 5 HT1A Receptor
- Receptor, 5-HT1A
- 5-Hydroxytryptamine 1A Receptor
- 1A Receptor, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptor
- 5-Hydroxytryptamine 1A Receptors
- 1A Receptors, 5-Hydroxytryptamine
- 5 Hydroxytryptamine 1A Receptors
- Receptors, 5-Hydroxytryptamine 1A
- Serotonin, 5-HT1a Receptor
- 5-HT1a Receptor Serotonin
- Receptor Serotonin, 5-HT1a
- Serotonin, 5 HT1a Receptor
- Serotonin 1A Receptor
- Receptor, Serotonin 1A
- Serotonin Receptor, 5-HT1A
- 5-HT1A Serotonin Receptor
- Receptor, 5-HT1A Serotonin
- Serotonin Receptor, 5 HT1A
- 5-HT(1A) Receptor
- Receptor, 5-Hydroxytryptamine 1A
- Receptor, 5 Hydroxytryptamine 1A
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Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT1A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.670.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.670.800.100.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.695.800.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.695.800.100.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT1 [D12.776.543.750.720.850.100]
- Receptor, Serotonin, 5-HT1A [D12.776.543.750.720.850.100.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT1A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT1A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT1A" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 1 | 0 | 1 | | 2005 | 1 | 1 | 2 | | 2008 | 1 | 1 | 2 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 3 | 1 | 4 | | 2014 | 0 | 1 | 1 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 1 | 2 | | 2017 | 1 | 1 | 2 | | 2018 | 1 | 1 | 2 | | 2019 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT1A" by people in Profiles.
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Lieb MW, Weidner M, Arnold MR, Loupy KM, Nguyen KT, Hassell JE, Schnabel KS, Kern R, Day HEW, Lesch KP, Waider J, Lowry CA. Effects of maternal separation on serotonergic systems in the dorsal and median raphe nuclei of adult male Tph2-deficient mice. Behav Brain Res. 2019 11 05; 373:112086.
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Cunningham AM, Santos TL, Gutzeit VA, Hamilton H, Hen R, Donaldson ZR. Functional Interrogation of a Depression-Related Serotonergic Single Nucleotide Polymorphism, rs6295, Using a Humanized Mouse Model. ACS Chem Neurosci. 2019 07 17; 10(7):3197-3206.
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Arnold MR, Williams PH, McArthur JA, Archuleta AR, O'Neill CE, Hassell JE, Smith DG, Bachtell RK, Lowry CA. Effects of chronic caffeine exposure during adolescence and subsequent acute caffeine challenge during adulthood on rat brain serotonergic systems. Neuropharmacology. 2019 04; 148:257-271.
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Philippe TJ, Vahid-Ansari F, Donaldson ZR, Le Fran?ois B, Zahrai A, Turcotte-Cardin V, Daigle M, James J, Hen R, Merali Z, Albert PR. Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes. Sci Rep. 2018 04 10; 8(1):5788.
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Fox JH, Hassell JE, Siebler PH, Arnold MR, Lamb AK, Smith DG, Day HEW, Smith TM, Simmerman EM, Outzen AA, Holmes KS, Brazell CJ, Lowry CA. Preimmunization with a heat-killed preparation of Mycobacterium vaccae enhances fear extinction in the fear-potentiated startle paradigm. Brain Behav Immun. 2017 Nov; 66:70-84.
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Roncon CM, Yamashita PSM, Frias AT, Audi EA, Graeff FG, Coimbra NC, Zangrossi H. ?-Opioid and 5-HT1A receptors in the dorsomedial hypothalamus interact for the regulation of panic-related defensive responses. J Psychopharmacol. 2017 06; 31(6):715-721.
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Mika A, Day HE, Martinez A, Rumian NL, Greenwood BN, Chichlowski M, Berg BM, Fleshner M. Early life diets with prebiotics and bioactive milk fractions attenuate the impact of stress on learned helplessness behaviours and alter gene expression within neural circuits important for stress resistance. Eur J Neurosci. 2017 02; 45(3):342-357.
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Donaldson ZR, le Francois B, Santos TL, Almli LM, Boldrini M, Champagne FA, Arango V, Mann JJ, Stockmeier CA, Galfalvy H, Albert PR, Ressler KJ, Hen R. The functional serotonin 1a receptor promoter polymorphism, rs6295, is associated with psychiatric illness and differences in transcription. Transl Psychiatry. 2016 Mar 01; 6:e746.
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Courtney NA, Ford CP. Mechanisms of 5-HT1A receptor-mediated transmission in dorsal raphe serotonin neurons. J Physiol. 2016 Feb 15; 594(4):953-65.
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Samuels BA, Anacker C, Hu A, Levinstein MR, Pickenhagen A, Tsetsenis T, Madro?al N, Donaldson ZR, Drew LJ, Dranovsky A, Gross CT, Tanaka KF, Hen R. 5-HT1A receptors on mature dentate gyrus granule cells are critical for the antidepressant response. Nat Neurosci. 2015 Nov; 18(11):1606-16.
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