 11-beta-Hydroxysteroid Dehydrogenase Type 1
"11-beta-Hydroxysteroid Dehydrogenase Type 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A low-affinity 11 beta-hydroxysteroid dehydrogenase found in a variety of tissues, most notably in LIVER; LUNG; ADIPOSE TISSUE; vascular tissue; OVARY; and the CENTRAL NERVOUS SYSTEM. The enzyme acts reversibly and can use either NAD or NADP as cofactors.
| Descriptor ID |
D043205
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| MeSH Number(s) |
D08.811.682.047.436.174.300 D08.811.682.047.820.100.300
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| Concept/Terms |
11-beta-Hydroxysteroid Dehydrogenase Type 1- 11-beta-Hydroxysteroid Dehydrogenase Type 1
- 11beta-HSD1 Reductase
- 11beta HSD1 Reductase
- 11beta-HSD1
- 11beta-Hydroxysteroid Dehydrogenase Type 1
- 11beta Hydroxysteroid Dehydrogenase Type 1
- 11 beta-Hydroxysteroid Dehydrogenase Type 1
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Below are MeSH descriptors whose meaning is more general than "11-beta-Hydroxysteroid Dehydrogenase Type 1".
Below are MeSH descriptors whose meaning is more specific than "11-beta-Hydroxysteroid Dehydrogenase Type 1".
This graph shows the total number of publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 1" by people in this website by year, and whether "11-beta-Hydroxysteroid Dehydrogenase Type 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2009 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2012 | 1 | 0 | 1 | | 2014 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 | | 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "11-beta-Hydroxysteroid Dehydrogenase Type 1" by people in Profiles.
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Faust HJ, Cheng TY, Korsunsky I, Watts GFM, Gal-Oz ST, Trim WV, Kongthong S, Jonsson AH, Simmons DP, Zhang F, Padera R, Chubinskaya S, Wei K, Raychaudhuri S, Lynch L, Moody DB, Brenner MB. Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis. Nat Commun. 2024 11 14; 15(1):9859.
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Shimada-Omori R, Yamasaki K, Koike S, Yamauchi T, Aiba S. TLR3 augments glucocorticoid-synthetic enzymes expression in epidermal keratinocytes; Implications of glucocorticoid metabolism in rosacea epidermis. J Dermatol Sci. 2020 Oct; 100(1):58-66.
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Loerz C, Staab-Weijnitz C, Huebbe P, Giller K, Metges C, Rimbach G, Maser E. Regulation of 11?-hydroxysteroid dehydrogenase type 1 following caloric restriction and re-feeding is species dependent. Chem Biol Interact. 2017 Oct 01; 276:95-104.
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Tesic V, Perovic M, Lazic D, Kojic S, Smiljanic K, Ruzdijic S, Rakic L, Kanazir S. Long-term intermittent feeding restores impaired GR signaling in the hippocampus of aged rat. J Steroid Biochem Mol Biol. 2015 May; 149:43-52.
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Barrientos RM, Thompson VM, Kitt MM, Amat J, Hale MW, Frank MG, Crysdale NY, Stamper CE, Hennessey PA, Watkins LR, Spencer RL, Lowry CA, Maier SF. Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia. Neurobiol Aging. 2015 Mar; 36(3):1483-95.
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Gyllenhammer LE, Alderete TL, Mahurka S, Allayee H, Goran MI. Adipose tissue 11?HSD1 gene expression, ?cell function and ectopic fat in obese African Americans versus Hispanics. Obesity (Silver Spring). 2014 Jan; 22(1):14-8.
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Han Y, Staab-Weijnitz CA, Xiong G, Maser E. Identification of microRNAs as a potential novel regulatory mechanism in HSD11B1 expression. J Steroid Biochem Mol Biol. 2013 Jan; 133:129-39.
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Blum A, Loerz C, Martin HJ, Staab-Weijnitz CA, Maser E. Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11?-hydroxysteroid dehydrogenase type 1 inhibitor. J Steroid Biochem Mol Biol. 2012 Jan; 128(1-2):51-5.
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Dovio A, Sartori ML, De Francia S, Mussino S, Perotti P, Saba L, Abbadessa G, Racca S, Angeli A. Differential expression of determinants of glucocorticoid sensitivity in androgen-dependent and androgen-independent human prostate cancer cell lines. J Steroid Biochem Mol Biol. 2009 Aug; 116(1-2):29-36.
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