Mifepristone
"Mifepristone" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary CUSHING SYNDROME.
Descriptor ID |
D015735
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MeSH Number(s) |
D04.210.500.365.415.580
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Concept/Terms |
R-38486- R-38486
- R 38486
- RU-486
- RU 486
- RU486
- R38486
- RU-38486
- RU 38486
- RU38486
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Below are MeSH descriptors whose meaning is more general than "Mifepristone".
Below are MeSH descriptors whose meaning is more specific than "Mifepristone".
This graph shows the total number of publications written about "Mifepristone" by people in this website by year, and whether "Mifepristone" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 2 | 2 | 1995 | 0 | 1 | 1 | 1996 | 1 | 0 | 1 | 1997 | 2 | 1 | 3 | 1998 | 2 | 1 | 3 | 1999 | 0 | 1 | 1 | 2000 | 1 | 1 | 2 | 2001 | 1 | 3 | 4 | 2002 | 0 | 3 | 3 | 2003 | 0 | 3 | 3 | 2004 | 0 | 1 | 1 | 2007 | 0 | 1 | 1 | 2009 | 0 | 2 | 2 | 2010 | 0 | 2 | 2 | 2011 | 0 | 1 | 1 | 2013 | 0 | 1 | 1 | 2014 | 0 | 1 | 1 | 2016 | 0 | 1 | 1 | 2017 | 0 | 1 | 1 | 2018 | 0 | 1 | 1 | 2019 | 0 | 1 | 1 | 2020 | 1 | 1 | 2 | 2021 | 0 | 1 | 1 | 2022 | 0 | 3 | 3 | 2024 | 1 | 0 | 1 |
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Below are the most recent publications written about "Mifepristone" by people in Profiles.
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Sariahmed K, Christine PJ, Wang J, Prifti C, Sabharwal M, LaRochelle M. Medication and procedural abortion uptake during a period of increasing abortion hostility. Soc Sci Med. 2024 Sep; 356:117151.
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Cohen RH, Teal SB. Medication Abortion. JAMA. 2022 11 01; 328(17):1779.
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Cohen RH, Teal SB. Medication for Early Pregnancy Termination. JAMA. 2022 06 28; 327(24):2446-2447.
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Roe AH, Abernathy A, Flynn AN, McAllister A, Koelper NC, Sammel MD, Schreiber CA, Sonalkar S. Utility and Limitations of Human Chorionic Gonadotropin Levels for Remote Follow-up After Medical Management of Early Pregnancy Loss. Obstet Gynecol. 2022 06 01; 139(6):1149-1151.
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Flynn AN, Roe AH, Koelper N, McAllister A, Sammel MD, Schreiber CA. Timing and efficacy of mifepristone pretreatment for medical management of early pregnancy loss. Contraception. 2021 06; 103(6):404-407.
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Sequeira GR, Sahores A, Dalotto-Moreno T, Perrotta RM, Pataccini G, Vanzulli SI, Polo ML, Radisky DC, Sartorius CA, Novaro V, Lamb CA, Rabinovich GA, Salatino M, Lanari C. Enhanced Antitumor Immunity via Endocrine Therapy Prevents Mammary Tumor Relapse and Increases Immune Checkpoint Blockade Sensitivity. Cancer Res. 2021 03 01; 81(5):1375-1387.
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Sonalkar S, Koelper N, Creinin MD, Atrio JM, Sammel MD, McAllister A, Schreiber CA. Management of early pregnancy loss with mifepristone and misoprostol: clinical predictors of treatment success from a randomized trial. Am J Obstet Gynecol. 2020 10; 223(4):551.e1-551.e7.
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Frank MG, Annis JL, Watkins LR, Maier SF. Glucocorticoids mediate stress induction of the alarmin HMGB1 and reduction of the microglia checkpoint receptor CD200R1 in limbic brain structures. Brain Behav Immun. 2019 08; 80:678-687.
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Cao Y, Liu H, Gao L, Lu L, Du L, Bai H, Li J, Said S, Wang XJ, Song J, Serkova N, Wei M, Xiao J, Lu SL. Cooperation Between Pten and Smad4 in Murine Salivary Gland Tumor Formation and Progression. Neoplasia. 2018 08; 20(8):764-774.
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Camden AJ, Szwarc MM, Chadchan SB, DeMayo FJ, O'Malley BW, Lydon JP, Kommagani R. Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization. Mol Hum Reprod. 2017 09 01; 23(9):646-653.
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