Killer Cells, Natural
"Killer Cells, Natural" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Bone marrow-derived lymphocytes that possess cytotoxic properties, classically directed against transformed and virus-infected cells. Unlike T CELLS; and B CELLS; NK CELLS are not antigen specific. The cytotoxicity of natural killer cells is determined by the collective signaling of an array of inhibitory and stimulatory CELL SURFACE RECEPTORS. A subset of T-LYMPHOCYTES referred to as NATURAL KILLER T CELLS shares some of the properties of this cell type.
| Descriptor ID |
D007694
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| MeSH Number(s) |
A11.118.637.555.567.537 A15.145.229.637.555.567.537 A15.382.490.555.567.537
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| Concept/Terms |
Killer Cells, Natural- Killer Cells, Natural
- NK Cells
- Cell, NK
- Cells, NK
- NK Cell
- Natural Killer Cells
- Cell, Natural Killer
- Cells, Natural Killer
- Killer Cell, Natural
- Natural Killer Cell
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Below are MeSH descriptors whose meaning is more general than "Killer Cells, Natural".
Below are MeSH descriptors whose meaning is more specific than "Killer Cells, Natural".
This graph shows the total number of publications written about "Killer Cells, Natural" by people in this website by year, and whether "Killer Cells, Natural" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1996 | 3 | 0 | 3 | | 1997 | 0 | 1 | 1 | | 1998 | 2 | 2 | 4 | | 1999 | 0 | 2 | 2 | | 2000 | 7 | 2 | 9 | | 2001 | 7 | 1 | 8 | | 2002 | 6 | 6 | 12 | | 2003 | 7 | 5 | 12 | | 2004 | 7 | 6 | 13 | | 2005 | 6 | 5 | 11 | | 2006 | 2 | 4 | 6 | | 2007 | 11 | 5 | 16 | | 2008 | 11 | 9 | 20 | | 2009 | 6 | 9 | 15 | | 2010 | 11 | 1 | 12 | | 2011 | 8 | 3 | 11 | | 2012 | 9 | 2 | 11 | | 2013 | 9 | 3 | 12 | | 2014 | 16 | 4 | 20 | | 2015 | 12 | 6 | 18 | | 2016 | 7 | 11 | 18 | | 2017 | 9 | 5 | 14 | | 2018 | 8 | 6 | 14 | | 2019 | 8 | 6 | 14 | | 2020 | 8 | 5 | 13 | | 2021 | 7 | 5 | 12 | | 2022 | 2 | 3 | 5 | | 2023 | 4 | 4 | 8 | | 2024 | 7 | 5 | 12 | | 2025 | 10 | 8 | 18 | | 2026 | 1 | 4 | 5 |
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Below are the most recent publications written about "Killer Cells, Natural" by people in Profiles.
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Gorska MM. Early Life Exposure to Air Pollutants and Childhood Asthma. Curr Allergy Asthma Rep. 2026 Sep 15; 26(1).
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Fox DA, Gurrea-Rubio M. Immunotherapy of cancer without induction of autoimmunity - CD6 as a therapeutic target. Front Immunol. 2026; 17:1845422.
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Sadeeq SA, Leaton LA, Kichula KM, Farias TDJ, Font-Porterias N, Pollock NR, Collora CE, Castelli EC, Gignoux CR, Norman PJ. PONG 2.0: allele imputation for the killer cell immunoglobulin-like receptors. Hum Mol Genet. 2026 Aug 10; 35(17).
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Lammers ML, Sholevar CJ, Karimzadeh M, Razmara AM, Cruz SM, Purl MC, Liu NM, Bakke D, Plagens RN, Elliott A, Sheng MK, Dongen CV, Tran T, Trinh AT, Nielsen RN, Kotamraju T, Farley LE, Iranpur KR, Mukarrama T, Gronchi A, Riedel RF, Monjazeb AM, Thorpe SW, Darrow MA, Kim J, Murphy WJ, Judge SJ, Canter RJ. Intratumoral TIGIT blockade augments antitumor responses and bypasses increased functionality of peripheral TIGIT+ NK cells in mouse and human models of bone and soft tissue sarcoma. J Immunother Cancer. 2026 Jul 22; 14(7).
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Kendirli PK, Erdem S, Kisaarslan AP, Gök V, Kayhan E, Özcan A, Dogan ME, Klein C, Ünal E, Eken A. A novel ELF4 gene variant disrupts T and NK cell function in a patient with immune thrombocytopenia (ITP). Inflamm Res. 2026 May 19; 75(1).
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Smith C, Curtis K, Bonham A, Boyer S, Navarro K, Fu J, Larrea N, Shlay JC, Lenz LL, Weinberg A. Maternal Inflammation Likely Drives Impaired Immune Responses to Respiratory Syncytial Virus in HIV-Exposed Uninfected Infants. J Infect Dis. 2026 Mar 17; 233(3):428-439.
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Johnson MJ, Crotteau M, Ghosh D, Vu T, Trinity L, Marches R, Ucar D, Levin MJ, Weinberg A. The recombinant zoster vaccine induces trained immunity in monocytes through persistent downregulation of TGFß. PLoS Pathog. 2025 12; 21(12):e1013759.
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Henrich IC, Billingsley MM, Jain K, Mondal S, Quick LN, Young R, Nguyen N, Oliveira AM, Blobel GA, Mitchell MJ, Chou MM. Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma. Mol Cancer Ther. 2025 Nov 03; 24(11):1802-1814.
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D'Antonio MA, Ware BC, DiLisio JE, Michaels MJ, Turner JA, Habenicht LM, Davenport BJ, Morrison TE, Pelanda R, Gapin L, Torres RM. Lpar5 regulates the CD8 T-cell response to persistent virus infection by altering exhaustion programming, survival, and NK receptor expression. J Immunol. 2025 Nov 01; 214(11):3055-3068.
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Niehrs A, Hertwig L, Buggert M, Nordström I, Statzu M, Pampena MB, Samer S, Knox JJ, Strunz B, Sun D, Nguyen S, Janoschka C, Xing Y, Wu VH, Sparrelid E, Alisjahbana A, Gao Y, Sleiers N, Strauss O, Filipovic I, Ponzetta A, Medina-Andrade I, Nilsén V, Jorns C, Cornillet M, Maucourant C, Ziegenhain C, Hengst J, Tweet G, Kroll K, Golden GJ, Wedemeyer H, Kürtüncü M, Dori Y, Itkin MG, Klotz L, Schaffer M, Ericzon BG, Ivarsson MA, Paiardini M, Nowak G, Willinger T, Reeves RK, Betts MR, Björkström NK. Transient tissue residency and lymphatic egress define human CD56bright NK cell homeostasis. Nat Immunol. 2025 Nov; 26(11):2004-2015.
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