Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Matthew Frank

Concepts (260)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Microglia
26
2024
251
5.360
Why?
Hippocampus
30
2025
895
3.220
Why?
Glucocorticoids
15
2025
594
3.150
Why?
Stress, Psychological
15
2025
1100
2.780
Why?
HMGB1 Protein
8
2019
50
2.510
Why?
Lipopolysaccharides
19
2024
886
2.490
Why?
Inflammasomes
7
2023
131
2.290
Why?
Inflammation
24
2024
2837
1.940
Why?
Rats, Sprague-Dawley
36
2025
2486
1.830
Why?
Rats
48
2025
5647
1.780
Why?
Inflammation Mediators
7
2018
513
1.780
Why?
Brain
10
2024
2668
1.410
Why?
Encephalitis
6
2018
136
1.360
Why?
Stress, Physiological
4
2017
443
1.280
Why?
Mycobacterium
5
2024
108
1.200
Why?
Receptors, Immunologic
3
2019
216
1.120
Why?
Alarmins
4
2018
26
1.120
Why?
Spike Glycoprotein, Coronavirus
2
2024
109
0.990
Why?
Psychoneuroimmunology
1
2025
10
0.940
Why?
Anti-Inflammatory Agents
3
2023
496
0.930
Why?
Interleukin-1beta
12
2025
372
0.910
Why?
Prefrontal Cortex
3
2025
301
0.880
Why?
Animals
59
2025
36940
0.870
Why?
NLR Family, Pyrin Domain-Containing 3 Protein
9
2023
151
0.840
Why?
Probiotics
2
2025
54
0.790
Why?
Aging
10
2018
1864
0.760
Why?
Interleukin 1 Receptor Antagonist Protein
4
2012
253
0.760
Why?
Corticosterone
8
2025
236
0.670
Why?
Adaptation, Psychological
1
2025
655
0.660
Why?
Cytokines
12
2018
2085
0.620
Why?
Limbic System
1
2019
47
0.610
Why?
Cisterna Magna
4
2013
8
0.600
Why?
Mycobacteriaceae
4
2023
24
0.590
Why?
Escherichia coli Infections
4
2014
111
0.570
Why?
Neuroimmunomodulation
6
2019
65
0.540
Why?
Intracellular Signaling Peptides and Proteins
1
2020
455
0.540
Why?
Memory Disorders
5
2016
164
0.530
Why?
Male
51
2025
67762
0.510
Why?
Antigens, CD
2
2017
521
0.500
Why?
Central Nervous System
2
2018
258
0.470
Why?
Receptors, Cytoplasmic and Nuclear
2
2015
220
0.470
Why?
Down-Regulation
1
2017
657
0.460
Why?
Methamphetamine
1
2015
63
0.450
Why?
Carrier Proteins
3
2015
771
0.450
Why?
Receptors, Glucocorticoid
4
2025
155
0.430
Why?
Peripheral Nervous System Diseases
3
2010
128
0.420
Why?
Memory
4
2018
248
0.400
Why?
Receptors, Interleukin-1
2
2012
216
0.390
Why?
Rats, Inbred F344
9
2018
265
0.370
Why?
Neuroglia
3
2011
173
0.340
Why?
Signal Transduction
3
2025
5079
0.320
Why?
Mifepristone
4
2019
64
0.310
Why?
Cytoskeletal Proteins
1
2009
158
0.300
Why?
Disease Susceptibility
1
2011
347
0.300
Why?
Hypothalamo-Hypophyseal System
2
2025
197
0.300
Why?
Endotoxins
1
2009
220
0.290
Why?
Reverse Transcriptase Polymerase Chain Reaction
5
2012
976
0.290
Why?
RNA, Messenger
6
2020
2833
0.280
Why?
RNA, Antisense
1
2007
17
0.270
Why?
Fibroblast Growth Factor 2
1
2007
87
0.260
Why?
Spinal Cord
7
2023
370
0.260
Why?
Oxidative Stress
1
2013
1317
0.250
Why?
Genes, MHC Class II
1
2006
74
0.250
Why?
Centrifugation
1
2005
30
0.240
Why?
Neuralgia
2
2023
133
0.240
Why?
Nerve Tissue Proteins
1
2009
596
0.240
Why?
Histocompatibility Antigens
1
2006
105
0.240
Why?
Helplessness, Learned
1
2025
68
0.230
Why?
Interleukins
1
2006
250
0.220
Why?
Cell Separation
1
2005
318
0.220
Why?
Diet, Western
1
2024
81
0.220
Why?
Pituitary-Adrenal System
1
2025
162
0.220
Why?
History, 21st Century
1
2025
213
0.220
Why?
Immunity, Innate
4
2015
828
0.220
Why?
History, 20th Century
1
2025
325
0.210
Why?
Dependovirus
1
2024
68
0.210
Why?
Cell Culture Techniques
1
2005
363
0.200
Why?
Mentors
1
2025
202
0.200
Why?
Pathogen-Associated Molecular Pattern Molecules
1
2021
7
0.190
Why?
Cytomegalovirus Infections
1
2023
192
0.190
Why?
Substance-Related Disorders
1
2011
1083
0.180
Why?
Interleukin-6
5
2023
778
0.180
Why?
Extinction, Psychological
1
2022
86
0.180
Why?
Weight Gain
1
2024
519
0.180
Why?
Immunization
3
2018
411
0.170
Why?
Phosphate-Binding Proteins
1
2020
6
0.170
Why?
Toll-Like Receptor 2
2
2013
115
0.170
Why?
Hot Temperature
2
2022
391
0.170
Why?
Adrenal Cortex Hormones
1
2024
565
0.170
Why?
Vaccination
2
2020
1381
0.170
Why?
Proteome
1
2025
472
0.170
Why?
Cerebrospinal Fluid Proteins
1
2020
8
0.160
Why?
Enzyme-Linked Immunosorbent Assay
3
2012
852
0.160
Why?
Interleukin-10
4
2014
302
0.160
Why?
Caspase 1
1
2020
144
0.160
Why?
Chronic Pain
1
2023
262
0.150
Why?
Hyperalgesia
3
2011
123
0.150
Why?
Depressive Disorder
1
2002
379
0.150
Why?
Toll-Like Receptor 4
2
2013
273
0.150
Why?
HEK293 Cells
1
2021
730
0.150
Why?
Killer Cells, Natural
1
2002
449
0.150
Why?
Interleukin-4
1
2020
216
0.150
Why?
Rats, Inbred BN
4
2012
58
0.150
Why?
Receptors, Pattern Recognition
1
2018
11
0.150
Why?
Humans
15
2025
137585
0.140
Why?
Bacterial Vaccines
1
2018
63
0.140
Why?
Blood Proteins
1
2020
252
0.140
Why?
Circadian Rhythm
3
2018
468
0.140
Why?
Macrophages
4
2023
1547
0.140
Why?
Fear
4
2022
338
0.140
Why?
Genetic Therapy
3
2010
297
0.140
Why?
Cognition
2
2018
1153
0.140
Why?
Up-Regulation
2
2013
843
0.140
Why?
Proteomics
2
2025
1111
0.130
Why?
Plasmids
2
2010
363
0.130
Why?
Frontal Lobe
1
2018
149
0.130
Why?
Time Factors
6
2016
6828
0.130
Why?
Amygdala
1
2017
191
0.130
Why?
Neurogenic Inflammation
1
2016
2
0.130
Why?
Lipid Metabolism
1
2020
518
0.130
Why?
Affect
1
2018
292
0.120
Why?
Adrenalectomy
2
2014
68
0.120
Why?
Drug Synergism
2
2013
382
0.120
Why?
Brain Mapping
1
2018
503
0.120
Why?
Illness Behavior
1
2014
9
0.120
Why?
Diet, High-Fat
1
2016
247
0.120
Why?
Real-Time Polymerase Chain Reaction
2
2013
346
0.110
Why?
Ventral Tegmental Area
1
2015
58
0.110
Why?
Anxiety
2
2020
1035
0.110
Why?
Spleen
2
2014
514
0.110
Why?
Circadian Clocks
1
2014
50
0.110
Why?
Behavior, Animal
3
2012
501
0.110
Why?
Laparotomy
2
2011
109
0.110
Why?
Nucleus Accumbens
1
2015
138
0.110
Why?
Corpus Striatum
1
2015
167
0.110
Why?
CD11b Antigen
2
2010
61
0.100
Why?
Liver
2
2014
1943
0.100
Why?
Injections, Spinal
6
2010
105
0.100
Why?
Cognitive Dysfunction
1
2018
383
0.100
Why?
Injections
2
2013
183
0.100
Why?
Physical Conditioning, Animal
2
2014
257
0.100
Why?
Sex Characteristics
1
2018
762
0.100
Why?
Pain
4
2011
756
0.090
Why?
Oxidation-Reduction
1
2015
1060
0.090
Why?
Interleukin-1
2
2007
965
0.090
Why?
Receptor, Serotonin, 5-HT1A
1
2011
38
0.090
Why?
DNA
2
2010
1459
0.090
Why?
Gram-Negative Bacterial Infections
1
2011
46
0.090
Why?
Dose-Response Relationship, Drug
3
2011
2057
0.090
Why?
Raphe Nuclei
1
2011
110
0.090
Why?
HIV Envelope Protein gp120
2
2010
60
0.090
Why?
Immune System
1
2012
177
0.080
Why?
Fever
1
2011
306
0.080
Why?
Transcription Factors
1
2018
1719
0.080
Why?
Genes, fos
1
2009
36
0.080
Why?
Microfilament Proteins
1
2010
133
0.080
Why?
Gene Expression Regulation
2
2010
2607
0.080
Why?
Hyperesthesia
2
2006
6
0.080
Why?
Calcium-Binding Proteins
1
2010
218
0.080
Why?
Gene Transfer Techniques
1
2010
170
0.070
Why?
Cognition Disorders
1
2012
496
0.070
Why?
Histocompatibility Antigens Class II
1
2010
367
0.070
Why?
Chemical and Drug Induced Liver Injury
1
2009
137
0.070
Why?
Hydrocortisone
1
2009
322
0.070
Why?
Neuronal Plasticity
1
2009
290
0.070
Why?
Tumor Necrosis Factor-alpha
2
2014
1242
0.070
Why?
Pain Threshold
1
2007
74
0.070
Why?
Foreign-Body Reaction
1
2007
31
0.060
Why?
Cells, Cultured
4
2018
4193
0.060
Why?
Catheterization
1
2007
179
0.060
Why?
DNA, Complementary
1
2006
272
0.060
Why?
Immunohistochemistry
2
2010
1738
0.060
Why?
Minocycline
1
2005
27
0.060
Why?
Disease Models, Animal
2
2013
4295
0.060
Why?
DNA Primers
1
2006
515
0.060
Why?
Chemokines, CX3C
1
2004
10
0.060
Why?
Intra-Abdominal Fat
1
2024
91
0.050
Why?
Adjuvants, Pharmaceutic
1
2023
11
0.050
Why?
Constriction
1
2023
47
0.050
Why?
Transduction, Genetic
1
2024
127
0.050
Why?
Transgenes
1
2024
180
0.050
Why?
Morphine
1
2004
158
0.050
Why?
Leptin
1
2024
236
0.050
Why?
Animals, Genetically Modified
1
2024
240
0.050
Why?
Genetic Vectors
1
2024
319
0.050
Why?
Administration, Oral
1
2025
816
0.050
Why?
Adjuvants, Immunologic
1
2023
226
0.050
Why?
Electroshock
2
2013
142
0.050
Why?
Tissue Distribution
2
2016
332
0.050
Why?
Gene Expression Regulation, Developmental
1
2006
860
0.040
Why?
Age of Onset
1
2002
518
0.040
Why?
Postoperative Complications
1
2012
2654
0.040
Why?
Psychiatric Status Rating Scales
1
2002
547
0.040
Why?
Adiposity
1
2024
518
0.040
Why?
Gene Expression Profiling
1
2006
1774
0.040
Why?
Escherichia coli
2
2016
815
0.040
Why?
Flow Cytometry
1
2002
1178
0.040
Why?
Pain Measurement
2
2011
521
0.040
Why?
Optical Fibers
1
2018
17
0.040
Why?
Vaccines, Inactivated
1
2018
68
0.040
Why?
Membrane Proteins
1
2004
1164
0.040
Why?
Immunoassay
1
2018
115
0.030
Why?
Neurons
1
2006
1590
0.030
Why?
Mice
2
2024
17787
0.030
Why?
Gastrointestinal Microbiome
1
2024
697
0.030
Why?
Memory, Long-Term
1
2016
12
0.030
Why?
Host-Pathogen Interactions
2
2011
364
0.030
Why?
Hormone Antagonists
1
2016
34
0.030
Why?
Analgesics, Opioid
1
2004
1000
0.030
Why?
DNA-Binding Proteins
1
2023
1502
0.030
Why?
Antibodies
1
2018
410
0.030
Why?
Lipids
1
2020
672
0.030
Why?
Random Allocation
1
2016
353
0.030
Why?
Rats, Wistar
1
2016
455
0.030
Why?
11-beta-Hydroxysteroid Dehydrogenase Type 1
1
2014
9
0.030
Why?
Mice, Inbred C57BL
1
2024
5757
0.030
Why?
Catalysis
1
2014
307
0.030
Why?
Phenotype
1
2002
3196
0.030
Why?
Alzheimer Disease
1
2020
560
0.030
Why?
Proteins
1
2020
1009
0.030
Why?
Conditioning, Classical
1
2014
103
0.030
Why?
Injections, Intraventricular
1
2012
55
0.020
Why?
Cell Line
1
2018
2847
0.020
Why?
Phosphatidylcholines
1
2013
147
0.020
Why?
Macrophages, Peritoneal
1
2011
94
0.020
Why?
Obesity
1
2024
2992
0.020
Why?
Physical Stimulation
1
2011
65
0.020
Why?
Glial Fibrillary Acidic Protein
1
2010
100
0.020
Why?
Cell Line, Tumor
1
2018
3412
0.020
Why?
Polyglycolic Acid
1
2010
43
0.020
Why?
Female
3
2023
73304
0.020
Why?
Serotonin
1
2011
323
0.020
Why?
Amnesia, Anterograde
1
2008
4
0.020
Why?
Particle Size
1
2010
394
0.020
Why?
Lactic Acid
1
2010
305
0.020
Why?
Action Potentials
1
2011
493
0.020
Why?
Exercise Test
1
2011
625
0.020
Why?
Parietal Lobe
1
2008
58
0.020
Why?
Hypothalamus
1
2008
153
0.020
Why?
Cyclooxygenase 1
1
2007
27
0.020
Why?
Microinjections
1
2006
86
0.020
Why?
Ligation
1
2006
92
0.020
Why?
Sciatic Nerve
1
2006
58
0.020
Why?
Evidence-Based Medicine
1
2010
740
0.020
Why?
Cyclooxygenase 2
1
2007
178
0.020
Why?
Receptors, HIV
1
2004
24
0.010
Why?
CX3C Chemokine Receptor 1
1
2004
19
0.010
Why?
Stress, Mechanical
1
2007
485
0.010
Why?
Nitric Oxide
1
2010
915
0.010
Why?
Chemokine CX3CL1
1
2004
24
0.010
Why?
Receptors, Cytokine
1
2004
36
0.010
Why?
Drug Administration Schedule
1
2006
786
0.010
Why?
Sialoglycoproteins
1
2004
159
0.010
Why?
Nanoparticles
1
2010
481
0.010
Why?
Drug Tolerance
1
2004
105
0.010
Why?
Neuroprotective Agents
1
2005
131
0.010
Why?
Analysis of Variance
1
2007
1316
0.010
Why?
Pain Management
1
2004
352
0.010
Why?
Middle Aged
1
2002
33479
0.010
Why?
Adult
1
2002
37929
0.010
Why?
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