Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Matthew Frank

Concepts (253)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Microglia
26
2024
232
5.550
Why?
Hippocampus
30
2025
871
3.310
Why?
HMGB1 Protein
8
2019
48
2.560
Why?
Lipopolysaccharides
19
2024
877
2.550
Why?
Glucocorticoids
14
2019
578
2.520
Why?
Inflammasomes
7
2023
126
2.340
Why?
Stress, Psychological
14
2019
1065
2.320
Why?
Inflammation
24
2024
2737
2.010
Why?
Inflammation Mediators
7
2018
505
1.810
Why?
Rats, Sprague-Dawley
35
2025
2396
1.720
Why?
Rats
47
2025
5482
1.700
Why?
Brain
10
2024
2669
1.420
Why?
Encephalitis
6
2018
132
1.390
Why?
Stress, Physiological
4
2017
414
1.330
Why?
Mycobacterium
5
2024
106
1.220
Why?
Receptors, Immunologic
3
2019
216
1.150
Why?
Alarmins
4
2018
24
1.150
Why?
Spike Glycoprotein, Coronavirus
2
2024
108
1.000
Why?
Anti-Inflammatory Agents
3
2023
480
0.960
Why?
NLR Family, Pyrin Domain-Containing 3 Protein
9
2023
149
0.860
Why?
Animals
58
2025
35307
0.850
Why?
Probiotics
2
2025
51
0.800
Why?
Aging
10
2018
1774
0.790
Why?
Interleukin 1 Receptor Antagonist Protein
4
2012
252
0.770
Why?
Interleukin-1beta
11
2023
372
0.720
Why?
Cytokines
12
2018
2013
0.640
Why?
Limbic System
1
2019
47
0.620
Why?
Cisterna Magna
4
2013
8
0.610
Why?
Escherichia coli Infections
4
2014
112
0.580
Why?
Mycobacteriaceae
3
2023
21
0.550
Why?
Intracellular Signaling Peptides and Proteins
1
2020
442
0.550
Why?
Neuroimmunomodulation
6
2019
69
0.550
Why?
Memory Disorders
5
2016
168
0.540
Why?
Antigens, CD
2
2017
489
0.520
Why?
Male
50
2025
63501
0.500
Why?
Central Nervous System
2
2018
253
0.480
Why?
Receptors, Cytoplasmic and Nuclear
2
2015
217
0.480
Why?
Down-Regulation
1
2017
636
0.480
Why?
Carrier Proteins
3
2015
742
0.460
Why?
Corticosterone
7
2019
220
0.460
Why?
Methamphetamine
1
2015
55
0.460
Why?
Peripheral Nervous System Diseases
3
2010
125
0.430
Why?
Memory
4
2018
255
0.400
Why?
Receptors, Interleukin-1
2
2012
218
0.400
Why?
Rats, Inbred F344
9
2018
259
0.380
Why?
Neuroglia
3
2011
163
0.350
Why?
Signal Transduction
3
2025
4926
0.330
Why?
Mifepristone
4
2019
64
0.310
Why?
Cytoskeletal Proteins
1
2009
146
0.310
Why?
Disease Susceptibility
1
2011
332
0.310
Why?
RNA, Messenger
6
2020
2703
0.300
Why?
Endotoxins
1
2009
220
0.300
Why?
Reverse Transcriptase Polymerase Chain Reaction
5
2012
947
0.290
Why?
RNA, Antisense
1
2007
15
0.280
Why?
Spinal Cord
7
2023
353
0.270
Why?
Fibroblast Growth Factor 2
1
2007
82
0.270
Why?
Oxidative Stress
1
2013
1265
0.260
Why?
Genes, MHC Class II
1
2006
73
0.250
Why?
Neuralgia
2
2023
126
0.250
Why?
Centrifugation
1
2005
30
0.250
Why?
Nerve Tissue Proteins
1
2009
569
0.250
Why?
Histocompatibility Antigens
1
2006
107
0.240
Why?
Interleukins
1
2006
241
0.230
Why?
Cell Separation
1
2005
316
0.220
Why?
Diet, Western
1
2024
79
0.220
Why?
Immunity, Innate
4
2015
803
0.220
Why?
Receptors, Glucocorticoid
3
2016
148
0.220
Why?
Dependovirus
1
2024
62
0.210
Why?
Cell Culture Techniques
1
2005
336
0.210
Why?
Substance-Related Disorders
1
2011
1019
0.190
Why?
Pathogen-Associated Molecular Pattern Molecules
1
2021
7
0.190
Why?
Interleukin-6
5
2023
720
0.190
Why?
Cytomegalovirus Infections
1
2023
189
0.190
Why?
Extinction, Psychological
1
2022
89
0.180
Why?
Weight Gain
1
2024
509
0.180
Why?
Hot Temperature
2
2022
369
0.180
Why?
Adrenal Cortex Hormones
1
2024
522
0.180
Why?
Phosphate-Binding Proteins
1
2020
5
0.170
Why?
Toll-Like Receptor 2
2
2013
113
0.170
Why?
Immunization
3
2018
411
0.170
Why?
Proteome
1
2025
438
0.170
Why?
Vaccination
2
2020
1347
0.170
Why?
Cerebrospinal Fluid Proteins
1
2020
8
0.170
Why?
Enzyme-Linked Immunosorbent Assay
3
2012
833
0.170
Why?
Interleukin-10
4
2014
300
0.170
Why?
Caspase 1
1
2020
143
0.160
Why?
Chronic Pain
1
2023
252
0.160
Why?
Depressive Disorder
1
2002
366
0.160
Why?
Killer Cells, Natural
1
2002
427
0.160
Why?
Toll-Like Receptor 4
2
2013
263
0.160
Why?
Hyperalgesia
3
2011
123
0.160
Why?
HEK293 Cells
1
2021
696
0.160
Why?
Interleukin-4
1
2020
212
0.160
Why?
Rats, Inbred BN
4
2012
59
0.150
Why?
Receptors, Pattern Recognition
1
2018
10
0.150
Why?
Circadian Rhythm
3
2018
413
0.150
Why?
Bacterial Vaccines
1
2018
62
0.150
Why?
Macrophages
4
2023
1484
0.140
Why?
Blood Proteins
1
2020
244
0.140
Why?
Cognition
2
2018
1122
0.140
Why?
Genetic Therapy
3
2010
288
0.140
Why?
Proteomics
2
2025
1054
0.140
Why?
Fear
4
2022
350
0.140
Why?
Plasmids
2
2010
358
0.140
Why?
Up-Regulation
2
2013
839
0.140
Why?
Frontal Lobe
1
2018
153
0.130
Why?
Time Factors
6
2016
6543
0.130
Why?
Lipid Metabolism
1
2020
497
0.130
Why?
Neurogenic Inflammation
1
2016
2
0.130
Why?
Humans
14
2023
129248
0.130
Why?
Amygdala
1
2017
198
0.130
Why?
Affect
1
2018
286
0.120
Why?
Adrenalectomy
2
2014
67
0.120
Why?
Drug Synergism
2
2013
370
0.120
Why?
Diet, High-Fat
1
2016
239
0.120
Why?
Illness Behavior
1
2014
9
0.120
Why?
Anxiety
2
2020
962
0.120
Why?
Real-Time Polymerase Chain Reaction
2
2013
328
0.120
Why?
Ventral Tegmental Area
1
2015
52
0.120
Why?
Spleen
2
2014
506
0.110
Why?
Prefrontal Cortex
2
2015
303
0.110
Why?
Circadian Clocks
1
2014
45
0.110
Why?
Brain Mapping
1
2018
574
0.110
Why?
Behavior, Animal
3
2012
506
0.110
Why?
Laparotomy
2
2011
106
0.110
Why?
Nucleus Accumbens
1
2015
126
0.110
Why?
Corpus Striatum
1
2015
159
0.110
Why?
Liver
2
2014
1839
0.110
Why?
CD11b Antigen
2
2010
60
0.110
Why?
Cognitive Dysfunction
1
2018
346
0.110
Why?
Injections, Spinal
6
2010
104
0.100
Why?
Injections
2
2013
174
0.100
Why?
Physical Conditioning, Animal
2
2014
229
0.100
Why?
Sex Characteristics
1
2018
736
0.100
Why?
Oxidation-Reduction
1
2015
1028
0.090
Why?
Interleukin-1
2
2007
959
0.090
Why?
Receptor, Serotonin, 5-HT1A
1
2011
38
0.090
Why?
DNA
2
2010
1396
0.090
Why?
Pain
4
2011
786
0.090
Why?
Gram-Negative Bacterial Infections
1
2011
45
0.090
Why?
Dose-Response Relationship, Drug
3
2011
2008
0.090
Why?
Raphe Nuclei
1
2011
110
0.090
Why?
HIV Envelope Protein gp120
2
2010
57
0.090
Why?
Immune System
1
2012
175
0.090
Why?
Hypothalamo-Hypophyseal System
1
2012
181
0.090
Why?
Transcription Factors
1
2018
1647
0.080
Why?
Fever
1
2011
298
0.080
Why?
Genes, fos
1
2009
33
0.080
Why?
Microfilament Proteins
1
2010
128
0.080
Why?
Gene Expression Regulation
2
2010
2537
0.080
Why?
Hyperesthesia
2
2006
7
0.080
Why?
Calcium-Binding Proteins
1
2010
211
0.080
Why?
Gene Transfer Techniques
1
2010
161
0.080
Why?
Histocompatibility Antigens Class II
1
2010
363
0.070
Why?
Cognition Disorders
1
2012
505
0.070
Why?
Chemical and Drug Induced Liver Injury
1
2009
132
0.070
Why?
Hydrocortisone
1
2009
306
0.070
Why?
Neuronal Plasticity
1
2009
279
0.070
Why?
Foreign-Body Reaction
1
2007
27
0.070
Why?
Tumor Necrosis Factor-alpha
2
2014
1202
0.070
Why?
Pain Threshold
1
2007
79
0.070
Why?
Cells, Cultured
4
2018
4076
0.060
Why?
Catheterization
1
2007
174
0.060
Why?
Immunohistochemistry
2
2010
1691
0.060
Why?
DNA, Complementary
1
2006
271
0.060
Why?
Disease Models, Animal
2
2013
4057
0.060
Why?
Minocycline
1
2005
27
0.060
Why?
DNA Primers
1
2006
510
0.060
Why?
Chemokines, CX3C
1
2004
11
0.060
Why?
Intra-Abdominal Fat
1
2024
88
0.060
Why?
Adjuvants, Pharmaceutic
1
2023
10
0.060
Why?
Constriction
1
2023
45
0.050
Why?
Transduction, Genetic
1
2024
128
0.050
Why?
Morphine
1
2004
137
0.050
Why?
Leptin
1
2024
219
0.050
Why?
Transgenes
1
2024
177
0.050
Why?
Animals, Genetically Modified
1
2024
228
0.050
Why?
Genetic Vectors
1
2024
312
0.050
Why?
Administration, Oral
1
2025
785
0.050
Why?
Adjuvants, Immunologic
1
2023
221
0.050
Why?
Electroshock
2
2013
147
0.050
Why?
Tissue Distribution
2
2016
315
0.050
Why?
Gene Expression Regulation, Developmental
1
2006
820
0.050
Why?
Postoperative Complications
1
2012
2473
0.040
Why?
Age of Onset
1
2002
496
0.040
Why?
Psychiatric Status Rating Scales
1
2002
528
0.040
Why?
Adiposity
1
2024
504
0.040
Why?
Gene Expression Profiling
1
2006
1688
0.040
Why?
Escherichia coli
2
2016
766
0.040
Why?
Flow Cytometry
1
2002
1155
0.040
Why?
Optical Fibers
1
2018
18
0.040
Why?
Pain Measurement
2
2011
506
0.040
Why?
Vaccines, Inactivated
1
2018
68
0.040
Why?
Membrane Proteins
1
2004
1117
0.040
Why?
Immunoassay
1
2018
107
0.040
Why?
Neurons
1
2006
1494
0.030
Why?
Mice
2
2024
16915
0.030
Why?
Gastrointestinal Microbiome
1
2024
640
0.030
Why?
Host-Pathogen Interactions
2
2011
351
0.030
Why?
Memory, Long-Term
1
2016
13
0.030
Why?
Lipids
1
2020
625
0.030
Why?
Hormone Antagonists
1
2016
32
0.030
Why?
Analgesics, Opioid
1
2004
909
0.030
Why?
DNA-Binding Proteins
1
2023
1446
0.030
Why?
Antibodies
1
2018
398
0.030
Why?
Random Allocation
1
2016
346
0.030
Why?
Rats, Wistar
1
2016
441
0.030
Why?
11-beta-Hydroxysteroid Dehydrogenase Type 1
1
2014
8
0.030
Why?
Mice, Inbred C57BL
1
2024
5439
0.030
Why?
Phenotype
1
2002
3074
0.030
Why?
Alzheimer Disease
1
2020
514
0.030
Why?
Proteins
1
2020
941
0.030
Why?
Catalysis
1
2014
307
0.030
Why?
Conditioning, Classical
1
2014
116
0.030
Why?
Injections, Intraventricular
1
2012
55
0.030
Why?
Cell Line
1
2018
2779
0.020
Why?
Phosphatidylcholines
1
2013
145
0.020
Why?
Obesity
1
2024
2879
0.020
Why?
Macrophages, Peritoneal
1
2011
92
0.020
Why?
Physical Stimulation
1
2011
75
0.020
Why?
Cell Line, Tumor
1
2018
3201
0.020
Why?
Glial Fibrillary Acidic Protein
1
2010
91
0.020
Why?
Polyglycolic Acid
1
2010
39
0.020
Why?
Female
3
2023
68543
0.020
Why?
Serotonin
1
2011
318
0.020
Why?
Amnesia, Anterograde
1
2008
5
0.020
Why?
Particle Size
1
2010
352
0.020
Why?
Lactic Acid
1
2010
298
0.020
Why?
Exercise Test
1
2011
612
0.020
Why?
Parietal Lobe
1
2008
49
0.020
Why?
Action Potentials
1
2011
485
0.020
Why?
Hypothalamus
1
2008
149
0.020
Why?
Cyclooxygenase 1
1
2007
26
0.020
Why?
Microinjections
1
2006
86
0.020
Why?
Ligation
1
2006
87
0.020
Why?
Evidence-Based Medicine
1
2010
712
0.020
Why?
Sciatic Nerve
1
2006
56
0.020
Why?
Cyclooxygenase 2
1
2007
177
0.020
Why?
Nanoparticles
1
2010
375
0.020
Why?
Stress, Mechanical
1
2007
467
0.010
Why?
CX3C Chemokine Receptor 1
1
2004
19
0.010
Why?
Receptors, HIV
1
2004
25
0.010
Why?
Chemokine CX3CL1
1
2004
23
0.010
Why?
Nitric Oxide
1
2010
895
0.010
Why?
Receptors, Cytokine
1
2004
35
0.010
Why?
Drug Administration Schedule
1
2006
768
0.010
Why?
Drug Tolerance
1
2004
90
0.010
Why?
Sialoglycoproteins
1
2004
155
0.010
Why?
Neuroprotective Agents
1
2005
122
0.010
Why?
Analysis of Variance
1
2007
1288
0.010
Why?
Pain Management
1
2004
324
0.010
Why?
Middle Aged
1
2002
31087
0.010
Why?
Adult
1
2002
35495
0.010
Why?
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