Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

David Irwin

Concepts (258)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Hemoglobins
10
2021
318
3.630
Why?
Anemia, Sickle Cell
9
2023
228
3.530
Why?
Hypoxia
10
2022
957
1.320
Why?
Altitude
4
2022
422
1.290
Why?
Altitude Sickness
3
2016
163
1.140
Why?
Hypertension, Pulmonary
7
2022
1784
1.140
Why?
Hemopexin
3
2021
13
1.030
Why?
Pulmonary Edema
2
2019
119
1.000
Why?
beta-Thalassemia
1
2023
23
0.920
Why?
Pulmonary Ventilation
1
2022
71
0.850
Why?
Haptoglobins
3
2018
49
0.810
Why?
Vascular Remodeling
3
2022
150
0.780
Why?
Capillary Permeability
4
2016
138
0.770
Why?
Beta vulgaris
1
2020
4
0.760
Why?
Rats
15
2022
5339
0.750
Why?
Pulmonary Artery
6
2022
1055
0.740
Why?
Emulsions
1
2019
44
0.710
Why?
Oxygen
4
2022
854
0.710
Why?
Endothelium, Vascular
3
2018
890
0.700
Why?
Vasodilator Agents
2
2013
328
0.690
Why?
Blood Substitutes
2
2009
23
0.670
Why?
Reactive Oxygen Species
2
2013
571
0.660
Why?
Rats, Sprague-Dawley
10
2019
2434
0.660
Why?
Fluorocarbons
1
2019
100
0.630
Why?
Lung
4
2018
3623
0.630
Why?
Animals
30
2023
33152
0.620
Why?
Microvessels
1
2018
73
0.600
Why?
Physical Exertion
1
2018
221
0.590
Why?
Toll-Like Receptor 9
1
2017
30
0.590
Why?
Carbonic Anhydrase Inhibitors
1
2016
18
0.590
Why?
Cerebral Veins
1
2016
16
0.580
Why?
Drug Delivery Systems
1
2019
306
0.580
Why?
Angiogenesis Inducing Agents
1
2016
23
0.580
Why?
Brain Edema
1
2016
61
0.570
Why?
Water
1
2019
422
0.570
Why?
Macrophages
2
2023
1311
0.570
Why?
Cerebral Arteries
1
2016
56
0.560
Why?
NF-E2-Related Factor 2
2
2013
82
0.540
Why?
Atrial Natriuretic Factor
2
2005
59
0.510
Why?
Muscle Contraction
1
2018
413
0.510
Why?
Angiogenesis Inhibitors
1
2016
218
0.510
Why?
Hemolysis
4
2021
171
0.510
Why?
Endothelial Cells
2
2013
717
0.490
Why?
Transcriptional Activation
2
2013
347
0.470
Why?
Vascular Diseases
2
2015
241
0.450
Why?
Myeloid Differentiation Factor 88
1
2013
95
0.450
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2014
244
0.430
Why?
Oxygen Consumption
2
2020
585
0.420
Why?
Mice
13
2023
15446
0.370
Why?
Glutaral
1
2009
15
0.350
Why?
Lung Diseases
2
2015
709
0.350
Why?
Phosphodiesterase 5 Inhibitors
1
2009
36
0.340
Why?
Phenylpropionates
2
2019
17
0.340
Why?
Phosphodiesterase Inhibitors
1
2009
86
0.340
Why?
Sulfones
1
2009
98
0.330
Why?
Pyridazines
2
2019
50
0.330
Why?
Muscle, Skeletal
1
2018
1515
0.330
Why?
Disease Progression
3
2023
2477
0.320
Why?
Inflammation
3
2023
2545
0.320
Why?
Vascular Resistance
3
2016
356
0.310
Why?
Endothelins
2
2018
62
0.310
Why?
Polymers
2
2009
482
0.300
Why?
Piperazines
1
2009
316
0.290
Why?
Lipid Peroxidation
3
2018
156
0.290
Why?
Respiration
2
2022
184
0.280
Why?
Nitric Oxide
3
2018
891
0.280
Why?
Vascular Endothelial Growth Factor A
1
2009
523
0.280
Why?
Disease Models, Animal
7
2022
3676
0.280
Why?
Cell Nucleus
1
2009
577
0.270
Why?
Male
16
2021
57476
0.270
Why?
Cardiac Output
3
2012
147
0.260
Why?
Capillary Leak Syndrome
1
2005
12
0.260
Why?
Muscle, Smooth, Vascular
4
2017
455
0.260
Why?
Neprilysin
1
2005
47
0.250
Why?
Heme
2
2021
54
0.240
Why?
Blood Pressure
4
2018
1656
0.230
Why?
Oxidation-Reduction
3
2018
935
0.230
Why?
Endothelin-1
1
2005
167
0.230
Why?
Intercellular Adhesion Molecule-1
2
2015
167
0.220
Why?
Mice, Inbred C57BL
4
2018
4887
0.220
Why?
Pulmonary Circulation
2
2019
423
0.220
Why?
Oxyhemoglobins
1
2021
22
0.200
Why?
Extracellular Vesicles
1
2023
76
0.200
Why?
Magnetics
1
2021
38
0.200
Why?
Humans
20
2023
118257
0.200
Why?
Scleroderma, Systemic
1
2022
93
0.200
Why?
Alternative Splicing
1
2022
190
0.190
Why?
Leukocytes, Mononuclear
1
2023
504
0.190
Why?
Muscle Proteins
1
2022
218
0.190
Why?
Metabolic Diseases
1
2021
103
0.190
Why?
Monocytes
1
2023
511
0.190
Why?
CD40 Antigens
1
2021
79
0.190
Why?
Nitrates
1
2020
77
0.190
Why?
Receptors, G-Protein-Coupled
1
2021
192
0.180
Why?
RNA, Long Noncoding
1
2022
160
0.180
Why?
Histone Deacetylases
2
2012
197
0.180
Why?
Up-Regulation
2
2013
862
0.180
Why?
Drug Evaluation, Preclinical
1
2019
178
0.170
Why?
Gadolinium
1
2019
78
0.170
Why?
Enoyl-CoA Hydratase
1
2018
9
0.170
Why?
Lipids
2
2023
591
0.170
Why?
Antibodies
1
2021
381
0.170
Why?
Metabolome
1
2021
288
0.170
Why?
Exercise Tolerance
1
2020
234
0.170
Why?
Double-Blind Method
2
2020
1683
0.170
Why?
Cell Line
2
2015
2693
0.160
Why?
Blood Gas Analysis
2
2008
69
0.160
Why?
Liver Diseases
1
2021
282
0.160
Why?
Carrier Proteins
1
2022
725
0.160
Why?
Aminophylline
1
2017
5
0.160
Why?
Proteomics
1
2023
850
0.150
Why?
Lipoproteins
1
2018
163
0.150
Why?
Antioxidants
2
2013
564
0.150
Why?
Acclimatization
1
2018
133
0.150
Why?
Anemia, Hemolytic
1
2017
19
0.150
Why?
Deferoxamine
1
2016
16
0.150
Why?
Cell Proliferation
2
2017
2262
0.150
Why?
Acetazolamide
1
2016
28
0.150
Why?
Cells, Cultured
6
2014
4044
0.150
Why?
Mice, Knockout
3
2022
2664
0.150
Why?
Dietary Supplements
1
2020
468
0.140
Why?
Niacinamide
1
2016
70
0.140
Why?
Myocytes, Cardiac
3
2022
470
0.140
Why?
Antihypertensive Agents
1
2019
436
0.140
Why?
Oxidative Stress
2
2012
1167
0.140
Why?
NF-kappa B
2
2013
664
0.140
Why?
Oligonucleotides
1
2016
140
0.140
Why?
Methemoglobin
2
2021
22
0.130
Why?
Cardiomyopathy, Dilated
1
2018
344
0.130
Why?
Signal Transduction
5
2017
4688
0.130
Why?
Vasoconstriction
1
2016
212
0.130
Why?
Indoles
1
2016
311
0.120
Why?
Hypertrophy, Right Ventricular
1
2015
146
0.120
Why?
Chloride Channels
1
2014
35
0.120
Why?
Genomics
1
2018
668
0.120
Why?
Cattle
2
2008
974
0.120
Why?
RNA, Small Interfering
3
2012
562
0.120
Why?
Catalase
1
2013
122
0.120
Why?
Cell Membrane Permeability
1
2013
87
0.110
Why?
Permeability
1
2013
154
0.110
Why?
Histone Deacetylase Inhibitors
2
2012
200
0.110
Why?
Iron
1
2015
247
0.110
Why?
Interleukin-6
1
2017
685
0.110
Why?
Ventricular Remodeling
2
2012
228
0.110
Why?
Cyclic N-Oxides
1
2012
31
0.110
Why?
Infusion Pumps
1
2012
32
0.110
Why?
Spin Labels
1
2012
50
0.110
Why?
Heart Failure
2
2022
1967
0.110
Why?
Mitochondrial Proteins
1
2014
224
0.100
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2013
219
0.100
Why?
Macrophages, Alveolar
1
2015
355
0.100
Why?
Superoxide Dismutase
1
2013
338
0.100
Why?
Cardiovascular Diseases
2
2021
1795
0.100
Why?
Gene Expression Regulation, Enzymologic
1
2012
287
0.100
Why?
Cerebellum
1
2013
203
0.100
Why?
Toll-Like Receptor 4
1
2013
330
0.100
Why?
Hydrogen Peroxide
1
2012
302
0.090
Why?
Microcirculation
2
2014
152
0.090
Why?
Blotting, Western
1
2012
1186
0.090
Why?
Sildenafil Citrate
1
2009
57
0.090
Why?
Pneumonia
1
2015
579
0.090
Why?
Active Transport, Cell Nucleus
1
2009
112
0.080
Why?
Female
7
2022
61262
0.080
Why?
NG-Nitroarginine Methyl Ester
1
2008
48
0.080
Why?
Hypoxia, Brain
1
2008
8
0.080
Why?
Purines
1
2009
160
0.080
Why?
Hemodynamics
1
2012
1002
0.080
Why?
Nitric Oxide Synthase
1
2008
226
0.080
Why?
Norepinephrine
1
2008
212
0.080
Why?
Exercise
1
2017
1647
0.070
Why?
Dogs
1
2008
369
0.070
Why?
Epinephrine
1
2008
166
0.070
Why?
Protein Isoforms
2
2022
345
0.070
Why?
RNA, Messenger
1
2013
2657
0.070
Why?
Treatment Outcome
1
2019
9319
0.070
Why?
Myocardium
1
2011
965
0.070
Why?
Stroke Volume
1
2008
513
0.070
Why?
Stress Fibers
1
2004
18
0.060
Why?
Kidney
1
2012
1351
0.060
Why?
Enzyme Inhibitors
1
2008
817
0.060
Why?
Heart Rate
1
2008
729
0.060
Why?
p38 Mitogen-Activated Protein Kinases
1
2004
274
0.060
Why?
Actins
1
2004
400
0.050
Why?
Catecholamines
1
2022
100
0.050
Why?
Hypertension
1
2011
1199
0.050
Why?
RNA Splicing Factors
1
2022
50
0.050
Why?
Thrombin
1
2023
133
0.050
Why?
Lung Neoplasms
1
2014
2216
0.050
Why?
In Situ Hybridization, Fluorescence
1
2022
310
0.050
Why?
Etanercept
1
2021
51
0.050
Why?
Lipopolysaccharides
1
2004
857
0.050
Why?
Case-Control Studies
2
2018
3156
0.050
Why?
Arrhythmias, Cardiac
1
2022
277
0.050
Why?
Ligands
1
2021
565
0.040
Why?
Intracellular Signaling Peptides and Proteins
1
2022
403
0.040
Why?
Tumor Necrosis Factor-alpha
1
2004
1159
0.040
Why?
Fatty Acids
1
2022
403
0.040
Why?
Tissue Donors
1
2021
334
0.040
Why?
Guinea Pigs
1
2018
151
0.040
Why?
Heart
1
2022
630
0.040
Why?
Cytochrome P-450 Enzyme System
1
2018
111
0.040
Why?
Linkage Disequilibrium
1
2018
273
0.040
Why?
Ventricular Dysfunction, Right
1
2021
232
0.040
Why?
Inflammation Mediators
1
2021
497
0.040
Why?
Cytoskeleton
1
2018
179
0.040
Why?
Genetics, Population
1
2018
207
0.040
Why?
Gene Regulatory Networks
1
2018
238
0.040
Why?
Proteins
1
2023
935
0.040
Why?
Sequence Analysis, RNA
1
2018
410
0.030
Why?
Heart Ventricles
2
2012
725
0.030
Why?
Mice, Inbred Strains
2
2014
404
0.030
Why?
Adenosine
1
2017
211
0.030
Why?
Mice, Transgenic
1
2021
2012
0.030
Why?
Sarcoma, Experimental
1
2014
5
0.030
Why?
Rats, Nude
1
2014
27
0.030
Why?
Intravital Microscopy
1
2014
25
0.030
Why?
Drug Therapy, Combination
1
2017
964
0.030
Why?
Heterografts
1
2014
129
0.030
Why?
Coronary Vessels
1
2016
233
0.030
Why?
Models, Biological
1
2021
1701
0.030
Why?
Adult
3
2023
31325
0.030
Why?
Transcription Factor RelA
1
2014
79
0.030
Why?
Swine
1
2016
719
0.030
Why?
Genotype
1
2018
1870
0.030
Why?
Blood Flow Velocity
1
2014
327
0.030
Why?
Familial Primary Pulmonary Hypertension
1
2014
191
0.030
Why?
Cytokines
1
2021
1880
0.030
Why?
Chemistry, Physical
1
2012
40
0.030
Why?
Mitochondria
1
2018
785
0.030
Why?
Neovascularization, Pathologic
1
2014
286
0.030
Why?
Fructans
1
1992
1
0.030
Why?
Genes, Immunoglobulin
1
1992
26
0.030
Why?
Young Adult
2
2018
10731
0.030
Why?
Immunoglobulin Light Chains
1
1992
35
0.030
Why?
Immunoglobulin Variable Region
1
1992
72
0.030
Why?
Immunoglobulin Heavy Chains
1
1992
72
0.030
Why?
MicroRNAs
1
2018
633
0.030
Why?
Gene Expression Profiling
1
2018
1590
0.030
Why?
Histone Deacetylase 6
1
2011
19
0.030
Why?
Benzamides
1
2012
176
0.020
Why?
Polymorphism, Single Nucleotide
1
2018
2057
0.020
Why?
Phenotype
1
2018
2937
0.020
Why?
Adenoviridae
1
2011
191
0.020
Why?
Regional Blood Flow
1
2012
417
0.020
Why?
RNA Interference
1
2011
459
0.020
Why?
Pyrimidines
1
2012
382
0.020
Why?
Pyridines
1
2012
436
0.020
Why?
Cohort Studies
1
2018
5078
0.020
Why?
Polymerase Chain Reaction
1
2011
1004
0.020
Why?
Middle Aged
2
2018
27511
0.020
Why?
Cell Line, Tumor
1
2014
2837
0.020
Why?
Antibodies, Monoclonal
1
1992
1279
0.020
Why?
Child
1
2023
19033
0.010
Why?
Breast Neoplasms
1
2014
1957
0.010
Why?
Adolescent
1
2017
18364
0.010
Why?
Antibody Diversity
1
1992
17
0.010
Why?
Immunoglobulin Isotypes
1
1992
32
0.010
Why?
Antibody Specificity
1
1992
182
0.010
Why?
Irwin's Networks
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