Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

Contact Us
If you have any questions or feedback please contact us.

Connection

David Irwin to Mice

This is a "connection" page, showing publications David Irwin has written about Mice.

 
Connection Strength
 
 
 
0.540
 
  1. Lucero MJ, Lisk C, Swindle D, Cendali F, Setua S, Thangaraju K, Khan A, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Khan S, Rana N, Westover N, Davizon-Castillio P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Niemeyer C, Cabrales P, Palmer A, D'Alessandro A, Buehler PW, Irwin DC. Combined haptoglobin and hemopexin therapy for the treatment of cardiopulmonary dysfunction in sickle cell disease. Biomed Pharmacother. 2025 Nov; 192:118595.
    View in: PubMed
    Score: 0.067
  2. Rana NK, Lisk C, Cendali F, Lucero MJ, Grier A, Setua S, Thangaraju K, Khan A, Reisz JA, Dzieciatkowska M, Pak DI, Swindle D, Danaher MX, Khan S, Westover N, Carter M, Hassell K, Nuss R, George G, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence is Present in Spleens and Livers from Berkeley Sickle Cell Anemia and ß-Thalassemia Mice. J Proteome Res. 2025 03 07; 24(3):1306-1316.
    View in: PubMed
    Score: 0.065
  3. Lucero MJ, Lisk C, Cendali F, Swindle D, Setua S, Thangaraju K, Pak DI, O'Boyle Q, Lu S, Tolson R, Zaeske S, Rana N, Khan S, Westover N, DavizonCastillo P, George G, Hassell K, Nuss R, Brinkman N, Gentinetta T, Palmer AF, D'Alessandro A, Buehler PW, Irwin DC. Targeting lung heme iron by aerosol hemopexin adminstration in sickle cell disease pulmonary hypertension. Free Radic Biol Med. 2025 Mar 01; 229:458-473.
    View in: PubMed
    Score: 0.064
  4. Lisk C, Cendali F, Setua S, Thangaraju K, Pak DI, Swindle D, Dzieciatkowska M, Gamboni F, Hassell K, Nuss R, George G, Davizon-Castillo P, Buehler PW, D'Alessandro A, Irwin DC. Metabolic and Proteomic Divergence Is Present in Circulating Monocytes and Tissue-Resident Macrophages from Berkeley Sickle Cell Anemia and ß-Thalassemia Mice. J Proteome Res. 2023 09 01; 22(9):2925-2935.
    View in: PubMed
    Score: 0.058
  5. Buehler PW, Swindle D, Pak DI, Ferguson SK, Majka SM, Karoor V, Moldovan R, Sintas C, Black J, Gentinetta T, Buzzi RM, Vallelian F, Wassmer A, Edler M, Bain J, Schu D, Hassell K, Nuss R, Schaer DJ, Irwin DC. Hemopexin dosing improves cardiopulmonary dysfunction in murine sickle cell disease. Free Radic Biol Med. 2021 11 01; 175:95-107.
    View in: PubMed
    Score: 0.051
  6. Ferguson SK, Redinius KM, Harral JW, Pak DI, Swindle DC, Hirai DM, Blackwell JR, Jones AM, Stenmark KR, Buehler PW, Irwin DC. The effect of dietary nitrate supplementation on the speed-duration relationship in mice with sickle cell disease. J Appl Physiol (1985). 2020 09 01; 129(3):474-482.
    View in: PubMed
    Score: 0.047
  7. Ferguson SK, Redinius K, Yalamanoglu A, Harral JW, Hyen Baek J, Pak D, Loomis Z, Hassell D, Eigenberger P, Nozik-Grayck E, Nuss R, Hassell K, Stenmark KR, Buehler PW, Irwin DC. Effects of living at moderate altitude on pulmonary vascular function and exercise capacity in mice with sickle cell anaemia. J Physiol. 2019 02; 597(4):1073-1085.
    View in: PubMed
    Score: 0.041
  8. Irwin DC, McCord JM, Nozik-Grayck E, Beckly G, Foreman B, Sullivan T, White M, T Crossno J, Bailey D, Flores SC, Majka S, Klemm D, van Patot MC. A potential role for reactive oxygen species and the HIF-1alpha-VEGF pathway in hypoxia-induced pulmonary vascular leak. Free Radic Biol Med. 2009 Jul 01; 47(1):55-61.
    View in: PubMed
    Score: 0.021
  9. Lucero MJ, Setua S, Thangaraju K, Khan A, Lamb DR, Lisk C, Swindle D, Cendali FI, Dzieciatkowska M, Stephenson D, Pak DI, Tolson R, Zaeske S, Rana NK, Khan S, Westover N, Davizon-Castillo P, George G, Hassell K, Nuss R, D'Alessandro A, Manolova V, Irwin DC, Buehler PW. Ferroportin inhibition attenuates pulmonary hypertension in hypoxic sickle cell disease mice. Blood Adv. 2026 May 12; 10(9):3229-3242.
    View in: PubMed
    Score: 0.018
  10. Lu S, Khan MA, Setua S, O'Boyle Q, Thangaraju K, Cabrales P, Swindle DC, Irwin DC, Buehler PW, Palmer AF. Transferrin Purification, Biophysical Characterization, and Lung Biodistribution in Sickle Cell Disease Mice. Biotechnol Bioeng. 2025 Oct; 122(10):2709-2723.
    View in: PubMed
    Score: 0.017
  11. Cendali FI, Lisk C, Dzieciatkowska M, LaCroix IS, Reisz JA, Harral J, Stephenson D, Hay AM, Wartchow EP, Darehshouri A, Dziewulska-Cronk KH, Buehler PW, Norris PJ, Deng X, Busch MP, Earley EJ, Page GP, Hansen KC, Zimring JC, Irwin DC, Nemkov T, D'Alessandro A. Increased exercise tolerance in humanized G6PD-deficient mice. Blood Adv. 2025 Jan 28; 9(2):321-334.
    View in: PubMed
    Score: 0.016
  12. Irwin DC, Patot MT, Tucker A, Bowen R. Neutral endopeptidase null mice are less susceptible to high altitude-induced pulmonary vascular leak. High Alt Med Biol. 2005; 6(4):311-9.
    View in: PubMed
    Score: 0.016
  13. Zhao Y, Riching AS, Knight WE, Chi C, Broadwell LJ, Du Y, Abdel-Hafiz M, Ambardekar AV, Irwin DC, Proenza C, Xu H, Leinwand LA, Walker LA, Woulfe KC, Bristow MR, Buttrick PM, Song K. Cardiomyocyte-Specific Long Noncoding RNA Regulates Alternative Splicing of the Triadin Gene in the Heart. Circulation. 2022 08 30; 146(9):699-714.
    View in: PubMed
    Score: 0.013
  14. Lee MH, Sanders L, Kumar R, Hernandez-Saavedra D, Yun X, Ford JA, Perez MJ, Mickael C, Gandjeva A, Koyanagi DE, Harral JW, Irwin DC, Kassa B, Eckel RH, Shimoda LA, Graham BB, Tuder RM. Contribution of fatty acid oxidation to the pathogenesis of pulmonary hypertension. Am J Physiol Lung Cell Mol Physiol. 2022 09 01; 323(3):L355-L371.
    View in: PubMed
    Score: 0.013
  15. Yalamanoglu A, Deuel JW, Hunt RC, Baek JH, Hassell K, Redinius K, Irwin DC, Schaer DJ, Buehler PW. Depletion of haptoglobin and hemopexin promote hemoglobin-mediated lipoprotein oxidation in sickle cell disease. Am J Physiol Lung Cell Mol Physiol. 2018 11 01; 315(5):L765-L774.
    View in: PubMed
    Score: 0.010
  16. Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension. Circulation. 2014 Apr 29; 129(17):1770-80.
    View in: PubMed
    Score: 0.008
  17. Reuland DJ, Khademi S, Castle CJ, Irwin DC, McCord JM, Miller BF, Hamilton KL. Upregulation of phase II enzymes through phytochemical activation of Nrf2 protects cardiomyocytes against oxidant stress. Free Radic Biol Med. 2013 Mar; 56:102-11.
    View in: PubMed
    Score: 0.007
  18. Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension. J Mol Cell Cardiol. 2011 Jul; 51(1):41-50.
    View in: PubMed
    Score: 0.006
  19. Boswell CM, Irwin DC, Goodnight J, Stein KE. Strain-dependent restricted VH and VL usage by anti-bacterial levan monoclonal antibodies. J Immunol. 1992 Jun 15; 148(12):3864-72.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Copyright © 2026 The Regents of the University of Colorado, a body corporate. All rights reserved. (Harvard PROFILES RNS software version: 2.11.1)