Chloride Channels
"Chloride Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell membrane glycoproteins that form channels to selectively pass chloride ions. Nonselective blockers include FENAMATES; ETHACRYNIC ACID; and TAMOXIFEN.
Descriptor ID |
D018118
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MeSH Number(s) |
D12.776.157.530.400.175 D12.776.543.550.450.175 D12.776.543.585.400.175
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Concept/Terms |
Chloride Channels- Chloride Channels
- Channels, Chloride
- Chlorine Channels
- Channels, Chlorine
- Ion Channel, Chloride
- Channel, Chloride Ion
- Chloride Ion Channel
- Ion Channels, Chloride
- Chloride Channel
- Channel, Chloride
- Chloride Ion Channels
- Channels, Chloride Ion
Calcium-Activated Chloride Channels- Calcium-Activated Chloride Channels
- Calcium Activated Chloride Channels
- Channels, Calcium-Activated Chloride
- Chloride Channels, Calcium-Activated
- CaCCs
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Below are MeSH descriptors whose meaning is more general than "Chloride Channels".
Below are MeSH descriptors whose meaning is more specific than "Chloride Channels".
This graph shows the total number of publications written about "Chloride Channels" by people in this website by year, and whether "Chloride Channels" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 1998 | 1 | 0 | 1 | 2001 | 0 | 2 | 2 | 2002 | 1 | 1 | 2 | 2003 | 2 | 1 | 3 | 2004 | 1 | 1 | 2 | 2005 | 0 | 1 | 1 | 2006 | 1 | 1 | 2 | 2007 | 0 | 2 | 2 | 2008 | 1 | 1 | 2 | 2009 | 0 | 1 | 1 | 2013 | 3 | 0 | 3 | 2014 | 1 | 1 | 2 | 2017 | 1 | 0 | 1 | 2018 | 1 | 0 | 1 | 2019 | 2 | 0 | 2 | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Chloride Channels" by people in Profiles.
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Bousseau S, Lahm T. Hungry for Chloride: Reprogramming Endothelial Cell Metabolism in Pulmonary Arterial Hypertension. Am J Respir Cell Mol Biol. 2023 01; 68(1):11-12.
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Nicoli ER, Weston MR, Hackbarth M, Becerril A, Larson A, Zein WM, Baker PR, Burke JD, Dorward H, Davids M, Huang Y, Adams DR, Zerfas PM, Chen D, Markello TC, Toro C, Wood T, Elliott G, Vu M, Zheng W, Garrett LJ, Tifft CJ, Gahl WA, Day-Salvatore DL, Mindell JA, Malicdan MCV. Lysosomal Storage and Albinism Due to Effects of a De Novo CLCN7 Variant on Lysosomal Acidification. Am J Hum Genet. 2019 06 06; 104(6):1127-1138.
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Duster AW, Garza CM, Aydintug BO, Negussie MB, Lin H. Adaptive Partitioning QM/MM for Molecular Dynamics Simulations: 6. Proton Transport through a Biological Channel. J Chem Theory Comput. 2019 Feb 12; 15(2):892-905.
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Singha B, Harper SL, Goldman AR, Bitler BG, Aird KM, Borowsky ME, Cadungog MG, Liu Q, Zhang R, Jean S, Drapkin R, Speicher DW. CLIC1 and CLIC4 complement CA125 as a diagnostic biomarker panel for all subtypes of epithelial ovarian cancer. Sci Rep. 2018 10 03; 8(1):14725.
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Mura CV, Delgado R, Delgado MG, Restrepo D, Bacigalupo J. A CLCA regulatory protein present in the chemosensory cilia of olfactory sensory neurons induces a Ca2+-activated Cl- current when transfected into HEK293. BMC Neurosci. 2017 08 11; 18(1):61.
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L?pez F, Delgado R, L?pez R, Bacigalupo J, Restrepo D. Transduction for pheromones in the main olfactory epithelium is mediated by the Ca2+ -activated channel TRPM5. J Neurosci. 2014 Feb 26; 34(9):3268-78.
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Wojciak-Stothard B, Abdul-Salam VB, Lao KH, Tsang H, Irwin DC, Lisk C, Loomis Z, Stenmark KR, Edwards JC, Yuspa SH, Howard LS, Edwards RJ, Rhodes CJ, Gibbs JS, Wharton J, Zhao L, Wilkins MR. Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension. Circulation. 2014 Apr 29; 129(17):1770-80.
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Church J, Pezeshki S, Davis C, Lin H. Charge transfer and polarization for chloride ions bound in ClC transport proteins: natural bond orbital and energy decomposition analyses. J Phys Chem B. 2013 Dec 19; 117(50):16029-43.
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Gonzalez-Silva C, Vera J, Bono MR, Gonz?lez-Billault C, Baxter B, Hansen A, Lopez R, Gibson EA, Restrepo D, Bacigalupo J. Ca2+-activated Cl- channels of the ClCa family express in the cilia of a subset of rat olfactory sensory neurons. PLoS One. 2013; 8(7):e69295.
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Schiffhauer ES, Vij N, Kovbasnjuk O, Kang PW, Walker D, Lee S, Zeitlin PL. Dual activation of CFTR and CLCN2 by lubiprostone in murine nasal epithelia. Am J Physiol Lung Cell Mol Physiol. 2013 Mar 01; 304(5):L324-31.
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