 David Irwin
Concepts (278)
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
| Name |
Number of Publications
|
Most Recent Publication
|
Publications by All Authors
|
Concept Score
|
Why?
|
|---|
| Anemia, Sickle Cell | 12 | 2025 | 253 | 5.270 |
Why?
| | Hemoglobins | 10 | 2021 | 337 | 3.280 |
Why?
| | Hemopexin | 4 | 2025 | 27 | 1.820 |
Why?
| | beta-Thalassemia | 2 | 2025 | 37 | 1.730 |
Why?
| | Hypertension, Pulmonary | 9 | 2025 | 1891 | 1.540 |
Why?
| | Hemolysis | 6 | 2025 | 199 | 1.310 |
Why?
| | Altitude Sickness | 4 | 2016 | 141 | 1.220 |
Why?
| | Exercise Tolerance | 4 | 2025 | 272 | 1.170 |
Why?
| | Altitude | 4 | 2022 | 462 | 1.150 |
Why?
| | Hypoxia | 10 | 2022 | 1081 | 1.130 |
Why?
| | Heme | 3 | 2025 | 77 | 1.110 |
Why?
| | Pulmonary Edema | 3 | 2019 | 106 | 1.090 |
Why?
| | Lung | 5 | 2025 | 3928 | 0.940 |
Why?
| | Iron | 2 | 2025 | 283 | 0.900 |
Why?
| | Muscle, Skeletal | 4 | 2025 | 1636 | 0.880 |
Why?
| | Spleen | 1 | 2025 | 508 | 0.810 |
Why?
| | Oxygen | 5 | 2024 | 914 | 0.800 |
Why?
| | Pulmonary Ventilation | 1 | 2022 | 77 | 0.770 |
Why?
| | Rats | 17 | 2024 | 5470 | 0.740 |
Why?
| | Haptoglobins | 3 | 2018 | 53 | 0.730 |
Why?
| | Vascular Remodeling | 3 | 2022 | 189 | 0.700 |
Why?
| | Capillary Permeability | 4 | 2016 | 140 | 0.700 |
Why?
| | Animals | 35 | 2025 | 35334 | 0.690 |
Why?
| | Proteome | 1 | 2025 | 440 | 0.680 |
Why?
| | Beta vulgaris | 1 | 2020 | 11 | 0.680 |
Why?
| | Pulmonary Artery | 6 | 2022 | 1075 | 0.670 |
Why?
| | Rats, Sprague-Dawley | 12 | 2024 | 2393 | 0.660 |
Why?
| | Endothelium, Vascular | 3 | 2018 | 895 | 0.650 |
Why?
| | Emulsions | 1 | 2019 | 51 | 0.650 |
Why?
| | Atrial Natriuretic Factor | 3 | 2005 | 56 | 0.640 |
Why?
| | Vasodilator Agents | 2 | 2013 | 325 | 0.630 |
Why?
| | Blood Substitutes | 2 | 2009 | 25 | 0.610 |
Why?
| | Reactive Oxygen Species | 2 | 2013 | 591 | 0.590 |
Why?
| | Fluorocarbons | 1 | 2019 | 109 | 0.570 |
Why?
| | Oxygen Consumption | 3 | 2024 | 663 | 0.550 |
Why?
| | Physical Exertion | 1 | 2018 | 208 | 0.550 |
Why?
| | Microvessels | 1 | 2018 | 81 | 0.550 |
Why?
| | Carbonic Anhydrase Inhibitors | 1 | 2016 | 14 | 0.540 |
Why?
| | Toll-Like Receptor 9 | 1 | 2017 | 30 | 0.530 |
Why?
| | Cerebral Veins | 1 | 2016 | 15 | 0.530 |
Why?
| | Angiogenesis Inducing Agents | 1 | 2016 | 23 | 0.530 |
Why?
| | Disease Models, Animal | 11 | 2025 | 4073 | 0.530 |
Why?
| | Drug Delivery Systems | 1 | 2019 | 337 | 0.520 |
Why?
| | Liver | 1 | 2025 | 1836 | 0.520 |
Why?
| | Brain Edema | 1 | 2016 | 61 | 0.520 |
Why?
| | Water | 1 | 2019 | 442 | 0.510 |
Why?
| | Cerebral Arteries | 1 | 2016 | 59 | 0.510 |
Why?
| | Macrophages | 2 | 2023 | 1486 | 0.490 |
Why?
| | NF-E2-Related Factor 2 | 2 | 2013 | 79 | 0.490 |
Why?
| | Mice | 16 | 2025 | 16973 | 0.480 |
Why?
| | Exercise | 2 | 2024 | 1931 | 0.470 |
Why?
| | Angiogenesis Inhibitors | 1 | 2016 | 218 | 0.470 |
Why?
| | Muscle Contraction | 1 | 2018 | 422 | 0.460 |
Why?
| | Endothelial Cells | 2 | 2013 | 739 | 0.450 |
Why?
| | Transcriptional Activation | 2 | 2013 | 366 | 0.430 |
Why?
| | Vascular Diseases | 2 | 2015 | 240 | 0.410 |
Why?
| | Mice, Inbred C57BL | 6 | 2025 | 5468 | 0.410 |
Why?
| | Myeloid Differentiation Factor 88 | 1 | 2013 | 97 | 0.400 |
Why?
| | Hypoxia-Inducible Factor 1, alpha Subunit | 3 | 2014 | 275 | 0.390 |
Why?
| | Glutaral | 1 | 2009 | 15 | 0.320 |
Why?
| | Lung Diseases | 2 | 2015 | 741 | 0.320 |
Why?
| | Proteomics | 3 | 2025 | 1053 | 0.320 |
Why?
| | Phosphodiesterase 5 Inhibitors | 1 | 2009 | 37 | 0.310 |
Why?
| | Phosphodiesterase Inhibitors | 1 | 2009 | 89 | 0.310 |
Why?
| | Oxidative Stress | 4 | 2025 | 1261 | 0.310 |
Why?
| | Phenylpropionates | 2 | 2019 | 18 | 0.310 |
Why?
| | Sulfones | 1 | 2009 | 108 | 0.300 |
Why?
| | Pyridazines | 2 | 2019 | 54 | 0.300 |
Why?
| | Male | 19 | 2025 | 63586 | 0.290 |
Why?
| | Inflammation | 3 | 2023 | 2741 | 0.290 |
Why?
| | Vascular Resistance | 3 | 2016 | 369 | 0.290 |
Why?
| | Disease Progression | 3 | 2023 | 2628 | 0.290 |
Why?
| | Endothelins | 2 | 2018 | 62 | 0.280 |
Why?
| | Polymers | 2 | 2009 | 479 | 0.280 |
Why?
| | Piperazines | 1 | 2009 | 339 | 0.260 |
Why?
| | Lipid Peroxidation | 3 | 2018 | 151 | 0.260 |
Why?
| | Respiration | 2 | 2022 | 193 | 0.260 |
Why?
| | Nitric Oxide | 3 | 2018 | 897 | 0.260 |
Why?
| | Vascular Endothelial Growth Factor A | 1 | 2009 | 527 | 0.260 |
Why?
| | Cell Nucleus | 1 | 2009 | 589 | 0.250 |
Why?
| | Physical Conditioning, Animal | 2 | 2025 | 236 | 0.240 |
Why?
| | Cardiac Output | 3 | 2012 | 157 | 0.240 |
Why?
| | Blood Pressure | 5 | 2018 | 1735 | 0.240 |
Why?
| | Capillary Leak Syndrome | 1 | 2005 | 12 | 0.240 |
Why?
| | Muscle, Smooth, Vascular | 4 | 2017 | 441 | 0.240 |
Why?
| | Humans | 23 | 2025 | 129527 | 0.230 |
Why?
| | Lignans | 1 | 2024 | 13 | 0.230 |
Why?
| | Heme Oxygenase-1 | 1 | 2025 | 62 | 0.230 |
Why?
| | Glucosephosphate Dehydrogenase Deficiency | 1 | 2025 | 30 | 0.230 |
Why?
| | Neprilysin | 1 | 2005 | 47 | 0.230 |
Why?
| | Glucosephosphate Dehydrogenase | 1 | 2025 | 56 | 0.230 |
Why?
| | Biphenyl Compounds | 1 | 2024 | 60 | 0.220 |
Why?
| | NAD | 1 | 2024 | 74 | 0.220 |
Why?
| | Sirtuin 3 | 1 | 2024 | 58 | 0.220 |
Why?
| | Aerosols | 1 | 2025 | 171 | 0.220 |
Why?
| | Intercellular Adhesion Molecule-1 | 2 | 2015 | 135 | 0.210 |
Why?
| | Endothelin-1 | 1 | 2005 | 178 | 0.210 |
Why?
| | Glycolysis | 1 | 2025 | 313 | 0.200 |
Why?
| | Pulmonary Circulation | 2 | 2019 | 428 | 0.200 |
Why?
| | Oxidation-Reduction | 3 | 2018 | 1029 | 0.200 |
Why?
| | Antibodies | 2 | 2021 | 398 | 0.190 |
Why?
| | Oxyhemoglobins | 1 | 2021 | 21 | 0.190 |
Why?
| | Magnetics | 1 | 2021 | 43 | 0.180 |
Why?
| | Scleroderma, Systemic | 1 | 2022 | 114 | 0.180 |
Why?
| | Extracellular Vesicles | 1 | 2023 | 129 | 0.170 |
Why?
| | Muscle Proteins | 1 | 2022 | 221 | 0.170 |
Why?
| | Metabolic Diseases | 1 | 2021 | 103 | 0.170 |
Why?
| | Leukocytes, Mononuclear | 1 | 2023 | 546 | 0.170 |
Why?
| | Monocytes | 1 | 2023 | 554 | 0.170 |
Why?
| | Alternative Splicing | 1 | 2022 | 216 | 0.170 |
Why?
| | CD40 Antigens | 1 | 2021 | 88 | 0.170 |
Why?
| | Nitrates | 1 | 2020 | 88 | 0.170 |
Why?
| | Up-Regulation | 2 | 2013 | 832 | 0.170 |
Why?
| | RNA, Long Noncoding | 1 | 2022 | 177 | 0.160 |
Why?
| | Receptors, G-Protein-Coupled | 1 | 2021 | 206 | 0.160 |
Why?
| | Endotoxins | 1 | 2001 | 220 | 0.160 |
Why?
| | Histone Deacetylases | 2 | 2012 | 211 | 0.160 |
Why?
| | Drug Evaluation, Preclinical | 1 | 2019 | 171 | 0.160 |
Why?
| | Gadolinium | 1 | 2019 | 78 | 0.160 |
Why?
| | Enoyl-CoA Hydratase | 1 | 2018 | 8 | 0.150 |
Why?
| | Lipids | 2 | 2023 | 614 | 0.150 |
Why?
| | Cell Line | 2 | 2015 | 2774 | 0.150 |
Why?
| | Metabolome | 1 | 2021 | 338 | 0.150 |
Why?
| | Double-Blind Method | 2 | 2020 | 1873 | 0.150 |
Why?
| | Carrier Proteins | 1 | 2022 | 740 | 0.150 |
Why?
| | Blood Gas Analysis | 2 | 2008 | 73 | 0.150 |
Why?
| | Liver Diseases | 1 | 2021 | 291 | 0.140 |
Why?
| | Aminophylline | 1 | 2017 | 10 | 0.140 |
Why?
| | Antioxidants | 2 | 2013 | 557 | 0.140 |
Why?
| | Lipoproteins | 1 | 2018 | 161 | 0.140 |
Why?
| | Cells, Cultured | 6 | 2014 | 4087 | 0.140 |
Why?
| | Anemia, Hemolytic | 1 | 2017 | 16 | 0.140 |
Why?
| | Cell Proliferation | 2 | 2017 | 2367 | 0.130 |
Why?
| | Deferoxamine | 1 | 2016 | 20 | 0.130 |
Why?
| | Acetazolamide | 1 | 2016 | 24 | 0.130 |
Why?
| | Acclimatization | 1 | 2018 | 167 | 0.130 |
Why?
| | Mice, Knockout | 3 | 2022 | 2887 | 0.130 |
Why?
| | Niacinamide | 1 | 2016 | 75 | 0.130 |
Why?
| | Dietary Supplements | 1 | 2020 | 532 | 0.130 |
Why?
| | Myocytes, Cardiac | 3 | 2022 | 492 | 0.130 |
Why?
| | NF-kappa B | 2 | 2013 | 666 | 0.120 |
Why?
| | Antihypertensive Agents | 1 | 2019 | 484 | 0.120 |
Why?
| | Oligonucleotides | 1 | 2016 | 145 | 0.120 |
Why?
| | Methemoglobin | 2 | 2021 | 20 | 0.120 |
Why?
| | Cardiomyopathy, Dilated | 1 | 2018 | 381 | 0.120 |
Why?
| | Signal Transduction | 5 | 2017 | 4916 | 0.120 |
Why?
| | Vasoconstriction | 1 | 2016 | 199 | 0.120 |
Why?
| | Hypertrophy, Right Ventricular | 1 | 2015 | 144 | 0.110 |
Why?
| | Cattle | 2 | 2008 | 959 | 0.110 |
Why?
| | Chloride Channels | 1 | 2014 | 38 | 0.110 |
Why?
| | Indoles | 1 | 2016 | 387 | 0.110 |
Why?
| | Genomics | 1 | 2018 | 715 | 0.110 |
Why?
| | RNA, Small Interfering | 3 | 2012 | 590 | 0.110 |
Why?
| | Catalase | 1 | 2013 | 128 | 0.110 |
Why?
| | Cell Membrane Permeability | 1 | 2013 | 82 | 0.100 |
Why?
| | Permeability | 1 | 2013 | 158 | 0.100 |
Why?
| | Histone Deacetylase Inhibitors | 2 | 2012 | 208 | 0.100 |
Why?
| | Interleukin-6 | 1 | 2017 | 724 | 0.100 |
Why?
| | Ventricular Remodeling | 2 | 2012 | 256 | 0.100 |
Why?
| | Cyclic N-Oxides | 1 | 2012 | 29 | 0.100 |
Why?
| | Infusion Pumps | 1 | 2012 | 32 | 0.100 |
Why?
| | Spin Labels | 1 | 2012 | 46 | 0.100 |
Why?
| | Heart Failure | 2 | 2022 | 2143 | 0.100 |
Why?
| | Basic Helix-Loop-Helix Transcription Factors | 1 | 2013 | 235 | 0.090 |
Why?
| | Macrophages, Alveolar | 1 | 2015 | 389 | 0.090 |
Why?
| | Mitochondrial Proteins | 1 | 2014 | 247 | 0.090 |
Why?
| | Gene Expression Regulation, Enzymologic | 1 | 2012 | 282 | 0.090 |
Why?
| | Toll-Like Receptor 4 | 1 | 2013 | 264 | 0.090 |
Why?
| | Cerebellum | 1 | 2013 | 218 | 0.090 |
Why?
| | Superoxide Dismutase | 1 | 2013 | 342 | 0.090 |
Why?
| | Cardiovascular Diseases | 2 | 2021 | 1997 | 0.090 |
Why?
| | Hydrogen Peroxide | 1 | 2012 | 317 | 0.090 |
Why?
| | Microcirculation | 2 | 2014 | 145 | 0.080 |
Why?
| | Blotting, Western | 1 | 2012 | 1199 | 0.080 |
Why?
| | Sildenafil Citrate | 1 | 2009 | 58 | 0.080 |
Why?
| | Pneumonia | 1 | 2015 | 618 | 0.080 |
Why?
| | Active Transport, Cell Nucleus | 1 | 2009 | 113 | 0.080 |
Why?
| | Hypoxia, Brain | 1 | 2008 | 8 | 0.070 |
Why?
| | NG-Nitroarginine Methyl Ester | 1 | 2008 | 47 | 0.070 |
Why?
| | Purines | 1 | 2009 | 171 | 0.070 |
Why?
| | Female | 7 | 2022 | 68650 | 0.070 |
Why?
| | Mice, Transgenic | 2 | 2025 | 2135 | 0.070 |
Why?
| | Epinephrine | 1 | 2008 | 141 | 0.070 |
Why?
| | Nitric Oxide Synthase | 1 | 2008 | 233 | 0.070 |
Why?
| | Norepinephrine | 1 | 2008 | 209 | 0.070 |
Why?
| | Hemodynamics | 1 | 2012 | 1094 | 0.070 |
Why?
| | Dogs | 1 | 2008 | 385 | 0.070 |
Why?
| | Protein Isoforms | 2 | 2022 | 392 | 0.060 |
Why?
| | RNA, Messenger | 1 | 2013 | 2697 | 0.060 |
Why?
| | Myocardium | 1 | 2011 | 981 | 0.060 |
Why?
| | Treatment Outcome | 1 | 2019 | 10232 | 0.060 |
Why?
| | Stress Fibers | 1 | 2004 | 18 | 0.060 |
Why?
| | Stroke Volume | 1 | 2008 | 593 | 0.060 |
Why?
| | Enzyme Inhibitors | 1 | 2008 | 825 | 0.060 |
Why?
| | Allyl Compounds | 1 | 2024 | 21 | 0.060 |
Why?
| | Kidney | 1 | 2012 | 1382 | 0.060 |
Why?
| | Sirtuins | 1 | 2024 | 39 | 0.060 |
Why?
| | Heart Rate | 1 | 2008 | 804 | 0.060 |
Why?
| | Phenols | 1 | 2024 | 97 | 0.050 |
Why?
| | p38 Mitogen-Activated Protein Kinases | 1 | 2004 | 277 | 0.050 |
Why?
| | Actins | 1 | 2004 | 406 | 0.050 |
Why?
| | Catecholamines | 1 | 2022 | 95 | 0.050 |
Why?
| | RNA Splicing Factors | 1 | 2022 | 52 | 0.050 |
Why?
| | Hypertension | 1 | 2011 | 1235 | 0.050 |
Why?
| | Thrombin | 1 | 2023 | 147 | 0.050 |
Why?
| | Lung Neoplasms | 1 | 2014 | 2342 | 0.050 |
Why?
| | In Situ Hybridization, Fluorescence | 1 | 2022 | 305 | 0.050 |
Why?
| | Lipopolysaccharides | 1 | 2004 | 872 | 0.040 |
Why?
| | Etanercept | 1 | 2021 | 56 | 0.040 |
Why?
| | Salmonella enteritidis | 1 | 2001 | 18 | 0.040 |
Why?
| | Case-Control Studies | 2 | 2018 | 3383 | 0.040 |
Why?
| | Arrhythmias, Cardiac | 1 | 2022 | 321 | 0.040 |
Why?
| | Tumor Necrosis Factor-alpha | 1 | 2004 | 1203 | 0.040 |
Why?
| | Ligands | 1 | 2021 | 619 | 0.040 |
Why?
| | Metabolomics | 1 | 2025 | 652 | 0.040 |
Why?
| | Erythrocytes | 1 | 2025 | 673 | 0.040 |
Why?
| | Intracellular Signaling Peptides and Proteins | 1 | 2022 | 443 | 0.040 |
Why?
| | Fatty Acids | 1 | 2022 | 427 | 0.040 |
Why?
| | Tissue Donors | 1 | 2021 | 391 | 0.040 |
Why?
| | Heart | 1 | 2022 | 643 | 0.040 |
Why?
| | Guinea Pigs | 1 | 2018 | 157 | 0.040 |
Why?
| | Ventricular Dysfunction, Right | 1 | 2021 | 231 | 0.040 |
Why?
| | Linkage Disequilibrium | 1 | 2018 | 257 | 0.040 |
Why?
| | Cytochrome P-450 Enzyme System | 1 | 2018 | 151 | 0.040 |
Why?
| | Inflammation Mediators | 1 | 2021 | 503 | 0.040 |
Why?
| | Genetics, Population | 1 | 2018 | 200 | 0.030 |
Why?
| | Cytoskeleton | 1 | 2018 | 181 | 0.030 |
Why?
| | Proteins | 1 | 2023 | 944 | 0.030 |
Why?
| | Gene Regulatory Networks | 1 | 2018 | 280 | 0.030 |
Why?
| | Sequence Analysis, RNA | 1 | 2018 | 426 | 0.030 |
Why?
| | Heart Ventricles | 2 | 2012 | 778 | 0.030 |
Why?
| | Mice, Inbred Strains | 2 | 2014 | 408 | 0.030 |
Why?
| | Adenosine | 1 | 2017 | 225 | 0.030 |
Why?
| | Sarcoma, Experimental | 1 | 2014 | 7 | 0.030 |
Why?
| | Rats, Nude | 1 | 2014 | 26 | 0.030 |
Why?
| | Intravital Microscopy | 1 | 2014 | 25 | 0.030 |
Why?
| | Drug Therapy, Combination | 1 | 2017 | 1037 | 0.030 |
Why?
| | Models, Biological | 1 | 2021 | 1717 | 0.030 |
Why?
| | Coronary Vessels | 1 | 2016 | 239 | 0.030 |
Why?
| | Heterografts | 1 | 2014 | 134 | 0.030 |
Why?
| | Swine | 1 | 2016 | 760 | 0.030 |
Why?
| | Genotype | 1 | 2018 | 1827 | 0.030 |
Why?
| | Transcription Factor RelA | 1 | 2014 | 85 | 0.030 |
Why?
| | Familial Primary Pulmonary Hypertension | 1 | 2014 | 198 | 0.030 |
Why?
| | Blood Flow Velocity | 1 | 2014 | 406 | 0.030 |
Why?
| | Adult | 3 | 2023 | 35505 | 0.030 |
Why?
| | Chemistry, Physical | 1 | 2012 | 37 | 0.030 |
Why?
| | Neovascularization, Pathologic | 1 | 2014 | 292 | 0.030 |
Why?
| | Cytokines | 1 | 2021 | 2018 | 0.030 |
Why?
| | Fructans | 1 | 1992 | 1 | 0.020 |
Why?
| | Genes, Immunoglobulin | 1 | 1992 | 28 | 0.020 |
Why?
| | Mitochondria | 1 | 2018 | 876 | 0.020 |
Why?
| | Immunoglobulin Light Chains | 1 | 1992 | 40 | 0.020 |
Why?
| | Immunoglobulin Variable Region | 1 | 1992 | 79 | 0.020 |
Why?
| | Immunoglobulin Heavy Chains | 1 | 1992 | 79 | 0.020 |
Why?
| | MicroRNAs | 1 | 2018 | 677 | 0.020 |
Why?
| | Gene Expression Profiling | 1 | 2018 | 1684 | 0.020 |
Why?
| | Young Adult | 2 | 2018 | 12438 | 0.020 |
Why?
| | Histone Deacetylase 6 | 1 | 2011 | 17 | 0.020 |
Why?
| | Polymorphism, Single Nucleotide | 1 | 2018 | 2062 | 0.020 |
Why?
| | Benzamides | 1 | 2012 | 203 | 0.020 |
Why?
| | Adenoviridae | 1 | 2011 | 190 | 0.020 |
Why?
| | Phenotype | 1 | 2018 | 3058 | 0.020 |
Why?
| | Regional Blood Flow | 1 | 2012 | 464 | 0.020 |
Why?
| | RNA Interference | 1 | 2011 | 450 | 0.020 |
Why?
| | Pyrimidines | 1 | 2012 | 458 | 0.020 |
Why?
| | Pyridines | 1 | 2012 | 478 | 0.020 |
Why?
| | Polymerase Chain Reaction | 1 | 2011 | 1031 | 0.020 |
Why?
| | Cohort Studies | 1 | 2018 | 5423 | 0.020 |
Why?
| | Cell Line, Tumor | 1 | 2014 | 3181 | 0.020 |
Why?
| | Middle Aged | 2 | 2018 | 31087 | 0.020 |
Why?
| | Antibodies, Monoclonal | 1 | 1992 | 1366 | 0.020 |
Why?
| | Child | 1 | 2023 | 20932 | 0.010 |
Why?
| | Breast Neoplasms | 1 | 2014 | 2101 | 0.010 |
Why?
| | Adolescent | 1 | 2017 | 20409 | 0.010 |
Why?
| | Antibody Diversity | 1 | 1992 | 16 | 0.010 |
Why?
| | Immunoglobulin Isotypes | 1 | 1992 | 34 | 0.010 |
Why?
| | Antibody Specificity | 1 | 1992 | 184 | 0.010 |
Why?
|
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Irwin's Networks
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