 David Irwin
Concepts (278)
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
| Name |
Number of Publications
|
Most Recent Publication
|
Publications by All Authors
|
Concept Score
|
Why?
|
|---|
| Anemia, Sickle Cell | 12 | 2025 | 252 | 5.330 |
Why?
| | Hemoglobins | 10 | 2021 | 336 | 3.330 |
Why?
| | Hemopexin | 4 | 2025 | 27 | 1.850 |
Why?
| | beta-Thalassemia | 2 | 2025 | 37 | 1.760 |
Why?
| | Hypertension, Pulmonary | 9 | 2025 | 1745 | 1.590 |
Why?
| | Hemolysis | 6 | 2025 | 199 | 1.330 |
Why?
| | Altitude Sickness | 4 | 2016 | 137 | 1.240 |
Why?
| | Exercise Tolerance | 4 | 2025 | 268 | 1.190 |
Why?
| | Altitude | 4 | 2022 | 447 | 1.170 |
Why?
| | Hypoxia | 10 | 2022 | 1036 | 1.150 |
Why?
| | Heme | 3 | 2025 | 76 | 1.130 |
Why?
| | Pulmonary Edema | 3 | 2019 | 104 | 1.110 |
Why?
| | Lung | 5 | 2025 | 3743 | 0.960 |
Why?
| | Iron | 2 | 2025 | 282 | 0.910 |
Why?
| | Muscle, Skeletal | 4 | 2025 | 1627 | 0.890 |
Why?
| | Spleen | 1 | 2025 | 507 | 0.820 |
Why?
| | Oxygen | 5 | 2024 | 899 | 0.810 |
Why?
| | Pulmonary Ventilation | 1 | 2022 | 76 | 0.790 |
Why?
| | Rats | 17 | 2024 | 5165 | 0.760 |
Why?
| | Haptoglobins | 3 | 2018 | 50 | 0.740 |
Why?
| | Vascular Remodeling | 3 | 2022 | 181 | 0.710 |
Why?
| | Capillary Permeability | 4 | 2016 | 131 | 0.710 |
Why?
| | Animals | 35 | 2025 | 34479 | 0.700 |
Why?
| | Proteome | 1 | 2025 | 430 | 0.700 |
Why?
| | Beta vulgaris | 1 | 2020 | 11 | 0.690 |
Why?
| | Rats, Sprague-Dawley | 12 | 2024 | 2239 | 0.680 |
Why?
| | Pulmonary Artery | 6 | 2022 | 1030 | 0.680 |
Why?
| | Endothelium, Vascular | 3 | 2018 | 847 | 0.660 |
Why?
| | Emulsions | 1 | 2019 | 43 | 0.660 |
Why?
| | Atrial Natriuretic Factor | 3 | 2005 | 56 | 0.650 |
Why?
| | Vasodilator Agents | 2 | 2013 | 321 | 0.640 |
Why?
| | Blood Substitutes | 2 | 2009 | 23 | 0.620 |
Why?
| | Reactive Oxygen Species | 2 | 2013 | 577 | 0.600 |
Why?
| | Fluorocarbons | 1 | 2019 | 109 | 0.580 |
Why?
| | Oxygen Consumption | 3 | 2024 | 669 | 0.560 |
Why?
| | Microvessels | 1 | 2018 | 79 | 0.560 |
Why?
| | Physical Exertion | 1 | 2018 | 208 | 0.550 |
Why?
| | Carbonic Anhydrase Inhibitors | 1 | 2016 | 14 | 0.550 |
Why?
| | Toll-Like Receptor 9 | 1 | 2017 | 31 | 0.540 |
Why?
| | Disease Models, Animal | 11 | 2025 | 3937 | 0.540 |
Why?
| | Cerebral Veins | 1 | 2016 | 15 | 0.540 |
Why?
| | Angiogenesis Inducing Agents | 1 | 2016 | 24 | 0.530 |
Why?
| | Drug Delivery Systems | 1 | 2019 | 325 | 0.530 |
Why?
| | Brain Edema | 1 | 2016 | 60 | 0.520 |
Why?
| | Liver | 1 | 2025 | 1826 | 0.520 |
Why?
| | Water | 1 | 2019 | 440 | 0.520 |
Why?
| | Cerebral Arteries | 1 | 2016 | 57 | 0.520 |
Why?
| | NF-E2-Related Factor 2 | 2 | 2013 | 67 | 0.500 |
Why?
| | Macrophages | 2 | 2023 | 1460 | 0.500 |
Why?
| | Mice | 16 | 2025 | 16602 | 0.490 |
Why?
| | Exercise | 2 | 2024 | 1929 | 0.480 |
Why?
| | Angiogenesis Inhibitors | 1 | 2016 | 215 | 0.480 |
Why?
| | Muscle Contraction | 1 | 2018 | 420 | 0.470 |
Why?
| | Endothelial Cells | 2 | 2013 | 698 | 0.460 |
Why?
| | Transcriptional Activation | 2 | 2013 | 356 | 0.430 |
Why?
| | Mice, Inbred C57BL | 6 | 2025 | 5272 | 0.420 |
Why?
| | Vascular Diseases | 2 | 2015 | 232 | 0.420 |
Why?
| | Myeloid Differentiation Factor 88 | 1 | 2013 | 95 | 0.410 |
Why?
| | Hypoxia-Inducible Factor 1, alpha Subunit | 3 | 2014 | 257 | 0.400 |
Why?
| | Glutaral | 1 | 2009 | 15 | 0.320 |
Why?
| | Lung Diseases | 2 | 2015 | 715 | 0.320 |
Why?
| | Proteomics | 3 | 2025 | 1009 | 0.320 |
Why?
| | Phosphodiesterase 5 Inhibitors | 1 | 2009 | 36 | 0.320 |
Why?
| | Oxidative Stress | 4 | 2025 | 1176 | 0.320 |
Why?
| | Phosphodiesterase Inhibitors | 1 | 2009 | 85 | 0.310 |
Why?
| | Phenylpropionates | 2 | 2019 | 16 | 0.310 |
Why?
| | Sulfones | 1 | 2009 | 108 | 0.300 |
Why?
| | Pyridazines | 2 | 2019 | 50 | 0.300 |
Why?
| | Inflammation | 3 | 2023 | 2654 | 0.290 |
Why?
| | Male | 19 | 2025 | 62858 | 0.290 |
Why?
| | Endothelins | 2 | 2018 | 59 | 0.290 |
Why?
| | Vascular Resistance | 3 | 2016 | 367 | 0.290 |
Why?
| | Disease Progression | 3 | 2023 | 2602 | 0.290 |
Why?
| | Polymers | 2 | 2009 | 471 | 0.280 |
Why?
| | Piperazines | 1 | 2009 | 336 | 0.270 |
Why?
| | Lipid Peroxidation | 3 | 2018 | 143 | 0.270 |
Why?
| | Vascular Endothelial Growth Factor A | 1 | 2009 | 500 | 0.260 |
Why?
| | Respiration | 2 | 2022 | 190 | 0.260 |
Why?
| | Nitric Oxide | 3 | 2018 | 882 | 0.260 |
Why?
| | Cell Nucleus | 1 | 2009 | 578 | 0.250 |
Why?
| | Physical Conditioning, Animal | 2 | 2025 | 230 | 0.250 |
Why?
| | Muscle, Smooth, Vascular | 4 | 2017 | 417 | 0.240 |
Why?
| | Cardiac Output | 3 | 2012 | 154 | 0.240 |
Why?
| | Capillary Leak Syndrome | 1 | 2005 | 12 | 0.240 |
Why?
| | Blood Pressure | 5 | 2018 | 1728 | 0.240 |
Why?
| | Humans | 23 | 2025 | 128418 | 0.240 |
Why?
| | Lignans | 1 | 2024 | 13 | 0.230 |
Why?
| | Heme Oxygenase-1 | 1 | 2025 | 59 | 0.230 |
Why?
| | Glucosephosphate Dehydrogenase Deficiency | 1 | 2025 | 30 | 0.230 |
Why?
| | Neprilysin | 1 | 2005 | 47 | 0.230 |
Why?
| | Glucosephosphate Dehydrogenase | 1 | 2025 | 55 | 0.230 |
Why?
| | Biphenyl Compounds | 1 | 2024 | 64 | 0.230 |
Why?
| | NAD | 1 | 2024 | 72 | 0.220 |
Why?
| | Sirtuin 3 | 1 | 2024 | 55 | 0.220 |
Why?
| | Aerosols | 1 | 2025 | 171 | 0.220 |
Why?
| | Intercellular Adhesion Molecule-1 | 2 | 2015 | 133 | 0.210 |
Why?
| | Glycolysis | 1 | 2025 | 293 | 0.210 |
Why?
| | Endothelin-1 | 1 | 2005 | 176 | 0.210 |
Why?
| | Pulmonary Circulation | 2 | 2019 | 416 | 0.210 |
Why?
| | Oxidation-Reduction | 3 | 2018 | 1001 | 0.200 |
Why?
| | Antibodies | 2 | 2021 | 391 | 0.190 |
Why?
| | Oxyhemoglobins | 1 | 2021 | 21 | 0.190 |
Why?
| | Magnetics | 1 | 2021 | 44 | 0.190 |
Why?
| | Scleroderma, Systemic | 1 | 2022 | 104 | 0.190 |
Why?
| | Extracellular Vesicles | 1 | 2023 | 129 | 0.180 |
Why?
| | Muscle Proteins | 1 | 2022 | 221 | 0.180 |
Why?
| | Metabolic Diseases | 1 | 2021 | 105 | 0.170 |
Why?
| | Leukocytes, Mononuclear | 1 | 2023 | 539 | 0.170 |
Why?
| | Monocytes | 1 | 2023 | 542 | 0.170 |
Why?
| | CD40 Antigens | 1 | 2021 | 88 | 0.170 |
Why?
| | Alternative Splicing | 1 | 2022 | 217 | 0.170 |
Why?
| | Nitrates | 1 | 2020 | 87 | 0.170 |
Why?
| | Up-Regulation | 2 | 2013 | 825 | 0.170 |
Why?
| | Endotoxins | 1 | 2001 | 216 | 0.170 |
Why?
| | Receptors, G-Protein-Coupled | 1 | 2021 | 203 | 0.170 |
Why?
| | RNA, Long Noncoding | 1 | 2022 | 178 | 0.170 |
Why?
| | Histone Deacetylases | 2 | 2012 | 210 | 0.170 |
Why?
| | Drug Evaluation, Preclinical | 1 | 2019 | 168 | 0.160 |
Why?
| | Gadolinium | 1 | 2019 | 77 | 0.160 |
Why?
| | Enoyl-CoA Hydratase | 1 | 2018 | 8 | 0.160 |
Why?
| | Lipids | 2 | 2023 | 620 | 0.150 |
Why?
| | Metabolome | 1 | 2021 | 319 | 0.150 |
Why?
| | Cell Line | 2 | 2015 | 2731 | 0.150 |
Why?
| | Double-Blind Method | 2 | 2020 | 1848 | 0.150 |
Why?
| | Blood Gas Analysis | 2 | 2008 | 71 | 0.150 |
Why?
| | Carrier Proteins | 1 | 2022 | 732 | 0.150 |
Why?
| | Liver Diseases | 1 | 2021 | 284 | 0.150 |
Why?
| | Aminophylline | 1 | 2017 | 7 | 0.150 |
Why?
| | Antioxidants | 2 | 2013 | 538 | 0.140 |
Why?
| | Lipoproteins | 1 | 2018 | 171 | 0.140 |
Why?
| | Cells, Cultured | 6 | 2014 | 4001 | 0.140 |
Why?
| | Anemia, Hemolytic | 1 | 2017 | 16 | 0.140 |
Why?
| | Deferoxamine | 1 | 2016 | 18 | 0.140 |
Why?
| | Cell Proliferation | 2 | 2017 | 2344 | 0.140 |
Why?
| | Acetazolamide | 1 | 2016 | 24 | 0.140 |
Why?
| | Acclimatization | 1 | 2018 | 160 | 0.140 |
Why?
| | Mice, Knockout | 3 | 2022 | 2755 | 0.130 |
Why?
| | Niacinamide | 1 | 2016 | 73 | 0.130 |
Why?
| | Myocytes, Cardiac | 3 | 2022 | 492 | 0.130 |
Why?
| | Dietary Supplements | 1 | 2020 | 531 | 0.130 |
Why?
| | NF-kappa B | 2 | 2013 | 649 | 0.130 |
Why?
| | Oligonucleotides | 1 | 2016 | 138 | 0.130 |
Why?
| | Antihypertensive Agents | 1 | 2019 | 485 | 0.130 |
Why?
| | Methemoglobin | 2 | 2021 | 20 | 0.120 |
Why?
| | Cardiomyopathy, Dilated | 1 | 2018 | 377 | 0.120 |
Why?
| | Signal Transduction | 5 | 2017 | 4826 | 0.120 |
Why?
| | Vasoconstriction | 1 | 2016 | 185 | 0.120 |
Why?
| | Hypertrophy, Right Ventricular | 1 | 2015 | 133 | 0.110 |
Why?
| | Chloride Channels | 1 | 2014 | 38 | 0.110 |
Why?
| | Cattle | 2 | 2008 | 960 | 0.110 |
Why?
| | Indoles | 1 | 2016 | 371 | 0.110 |
Why?
| | RNA, Small Interfering | 3 | 2012 | 571 | 0.110 |
Why?
| | Genomics | 1 | 2018 | 715 | 0.110 |
Why?
| | Catalase | 1 | 2013 | 122 | 0.110 |
Why?
| | Cell Membrane Permeability | 1 | 2013 | 80 | 0.110 |
Why?
| | Histone Deacetylase Inhibitors | 2 | 2012 | 207 | 0.110 |
Why?
| | Permeability | 1 | 2013 | 156 | 0.110 |
Why?
| | Interleukin-6 | 1 | 2017 | 716 | 0.100 |
Why?
| | Ventricular Remodeling | 2 | 2012 | 254 | 0.100 |
Why?
| | Cyclic N-Oxides | 1 | 2012 | 30 | 0.100 |
Why?
| | Infusion Pumps | 1 | 2012 | 31 | 0.100 |
Why?
| | Spin Labels | 1 | 2012 | 46 | 0.100 |
Why?
| | Heart Failure | 2 | 2022 | 2145 | 0.100 |
Why?
| | Basic Helix-Loop-Helix Transcription Factors | 1 | 2013 | 230 | 0.090 |
Why?
| | Macrophages, Alveolar | 1 | 2015 | 376 | 0.090 |
Why?
| | Mitochondrial Proteins | 1 | 2014 | 244 | 0.090 |
Why?
| | Gene Expression Regulation, Enzymologic | 1 | 2012 | 281 | 0.090 |
Why?
| | Toll-Like Receptor 4 | 1 | 2013 | 262 | 0.090 |
Why?
| | Cerebellum | 1 | 2013 | 217 | 0.090 |
Why?
| | Superoxide Dismutase | 1 | 2013 | 326 | 0.090 |
Why?
| | Cardiovascular Diseases | 2 | 2021 | 1999 | 0.090 |
Why?
| | Hydrogen Peroxide | 1 | 2012 | 308 | 0.090 |
Why?
| | Microcirculation | 2 | 2014 | 137 | 0.090 |
Why?
| | Blotting, Western | 1 | 2012 | 1164 | 0.080 |
Why?
| | Sildenafil Citrate | 1 | 2009 | 59 | 0.080 |
Why?
| | Pneumonia | 1 | 2015 | 598 | 0.080 |
Why?
| | Active Transport, Cell Nucleus | 1 | 2009 | 113 | 0.080 |
Why?
| | Hypoxia, Brain | 1 | 2008 | 8 | 0.080 |
Why?
| | NG-Nitroarginine Methyl Ester | 1 | 2008 | 46 | 0.080 |
Why?
| | Purines | 1 | 2009 | 169 | 0.070 |
Why?
| | Female | 7 | 2022 | 68154 | 0.070 |
Why?
| | Mice, Transgenic | 2 | 2025 | 2071 | 0.070 |
Why?
| | Epinephrine | 1 | 2008 | 136 | 0.070 |
Why?
| | Nitric Oxide Synthase | 1 | 2008 | 232 | 0.070 |
Why?
| | Norepinephrine | 1 | 2008 | 205 | 0.070 |
Why?
| | Hemodynamics | 1 | 2012 | 1081 | 0.070 |
Why?
| | Dogs | 1 | 2008 | 366 | 0.070 |
Why?
| | Protein Isoforms | 2 | 2022 | 378 | 0.060 |
Why?
| | RNA, Messenger | 1 | 2013 | 2675 | 0.060 |
Why?
| | Myocardium | 1 | 2011 | 965 | 0.060 |
Why?
| | Treatment Outcome | 1 | 2019 | 10152 | 0.060 |
Why?
| | Stress Fibers | 1 | 2004 | 18 | 0.060 |
Why?
| | Stroke Volume | 1 | 2008 | 586 | 0.060 |
Why?
| | Kidney | 1 | 2012 | 1302 | 0.060 |
Why?
| | Enzyme Inhibitors | 1 | 2008 | 809 | 0.060 |
Why?
| | Allyl Compounds | 1 | 2024 | 21 | 0.060 |
Why?
| | Sirtuins | 1 | 2024 | 37 | 0.060 |
Why?
| | Heart Rate | 1 | 2008 | 800 | 0.060 |
Why?
| | Phenols | 1 | 2024 | 96 | 0.050 |
Why?
| | p38 Mitogen-Activated Protein Kinases | 1 | 2004 | 269 | 0.050 |
Why?
| | Actins | 1 | 2004 | 401 | 0.050 |
Why?
| | Catecholamines | 1 | 2022 | 97 | 0.050 |
Why?
| | RNA Splicing Factors | 1 | 2022 | 51 | 0.050 |
Why?
| | Thrombin | 1 | 2023 | 142 | 0.050 |
Why?
| | Hypertension | 1 | 2011 | 1235 | 0.050 |
Why?
| | Lung Neoplasms | 1 | 2014 | 2328 | 0.050 |
Why?
| | In Situ Hybridization, Fluorescence | 1 | 2022 | 313 | 0.050 |
Why?
| | Lipopolysaccharides | 1 | 2004 | 856 | 0.050 |
Why?
| | Etanercept | 1 | 2021 | 56 | 0.050 |
Why?
| | Salmonella enteritidis | 1 | 2001 | 18 | 0.050 |
Why?
| | Case-Control Studies | 2 | 2018 | 3328 | 0.040 |
Why?
| | Metabolomics | 1 | 2025 | 599 | 0.040 |
Why?
| | Arrhythmias, Cardiac | 1 | 2022 | 316 | 0.040 |
Why?
| | Tumor Necrosis Factor-alpha | 1 | 2004 | 1185 | 0.040 |
Why?
| | Ligands | 1 | 2021 | 614 | 0.040 |
Why?
| | Erythrocytes | 1 | 2025 | 672 | 0.040 |
Why?
| | Fatty Acids | 1 | 2022 | 415 | 0.040 |
Why?
| | Intracellular Signaling Peptides and Proteins | 1 | 2022 | 431 | 0.040 |
Why?
| | Tissue Donors | 1 | 2021 | 388 | 0.040 |
Why?
| | Heart | 1 | 2022 | 635 | 0.040 |
Why?
| | Guinea Pigs | 1 | 2018 | 155 | 0.040 |
Why?
| | Cytochrome P-450 Enzyme System | 1 | 2018 | 128 | 0.040 |
Why?
| | Ventricular Dysfunction, Right | 1 | 2021 | 228 | 0.040 |
Why?
| | Linkage Disequilibrium | 1 | 2018 | 256 | 0.040 |
Why?
| | Inflammation Mediators | 1 | 2021 | 495 | 0.040 |
Why?
| | Genetics, Population | 1 | 2018 | 200 | 0.040 |
Why?
| | Cytoskeleton | 1 | 2018 | 180 | 0.040 |
Why?
| | Proteins | 1 | 2023 | 932 | 0.030 |
Why?
| | Gene Regulatory Networks | 1 | 2018 | 280 | 0.030 |
Why?
| | Heart Ventricles | 2 | 2012 | 765 | 0.030 |
Why?
| | Sequence Analysis, RNA | 1 | 2018 | 429 | 0.030 |
Why?
| | Mice, Inbred Strains | 2 | 2014 | 402 | 0.030 |
Why?
| | Adenosine | 1 | 2017 | 211 | 0.030 |
Why?
| | Sarcoma, Experimental | 1 | 2014 | 7 | 0.030 |
Why?
| | Rats, Nude | 1 | 2014 | 27 | 0.030 |
Why?
| | Intravital Microscopy | 1 | 2014 | 24 | 0.030 |
Why?
| | Drug Therapy, Combination | 1 | 2017 | 1009 | 0.030 |
Why?
| | Models, Biological | 1 | 2021 | 1691 | 0.030 |
Why?
| | Coronary Vessels | 1 | 2016 | 236 | 0.030 |
Why?
| | Heterografts | 1 | 2014 | 129 | 0.030 |
Why?
| | Swine | 1 | 2016 | 742 | 0.030 |
Why?
| | Transcription Factor RelA | 1 | 2014 | 79 | 0.030 |
Why?
| | Genotype | 1 | 2018 | 1828 | 0.030 |
Why?
| | Familial Primary Pulmonary Hypertension | 1 | 2014 | 183 | 0.030 |
Why?
| | Blood Flow Velocity | 1 | 2014 | 409 | 0.030 |
Why?
| | Chemistry, Physical | 1 | 2012 | 37 | 0.030 |
Why?
| | Adult | 3 | 2023 | 35300 | 0.030 |
Why?
| | Cytokines | 1 | 2021 | 1983 | 0.030 |
Why?
| | Neovascularization, Pathologic | 1 | 2014 | 290 | 0.030 |
Why?
| | Fructans | 1 | 1992 | 1 | 0.030 |
Why?
| | Mitochondria | 1 | 2018 | 848 | 0.030 |
Why?
| | Genes, Immunoglobulin | 1 | 1992 | 28 | 0.030 |
Why?
| | Immunoglobulin Light Chains | 1 | 1992 | 40 | 0.020 |
Why?
| | Immunoglobulin Variable Region | 1 | 1992 | 79 | 0.020 |
Why?
| | Immunoglobulin Heavy Chains | 1 | 1992 | 80 | 0.020 |
Why?
| | MicroRNAs | 1 | 2018 | 677 | 0.020 |
Why?
| | Gene Expression Profiling | 1 | 2018 | 1688 | 0.020 |
Why?
| | Young Adult | 2 | 2018 | 12312 | 0.020 |
Why?
| | Histone Deacetylase 6 | 1 | 2011 | 17 | 0.020 |
Why?
| | Benzamides | 1 | 2012 | 194 | 0.020 |
Why?
| | Polymorphism, Single Nucleotide | 1 | 2018 | 2062 | 0.020 |
Why?
| | Adenoviridae | 1 | 2011 | 189 | 0.020 |
Why?
| | Phenotype | 1 | 2018 | 3044 | 0.020 |
Why?
| | Regional Blood Flow | 1 | 2012 | 459 | 0.020 |
Why?
| | RNA Interference | 1 | 2011 | 441 | 0.020 |
Why?
| | Pyrimidines | 1 | 2012 | 445 | 0.020 |
Why?
| | Pyridines | 1 | 2012 | 475 | 0.020 |
Why?
| | Polymerase Chain Reaction | 1 | 2011 | 1020 | 0.020 |
Why?
| | Cohort Studies | 1 | 2018 | 5388 | 0.020 |
Why?
| | Cell Line, Tumor | 1 | 2014 | 3184 | 0.020 |
Why?
| | Middle Aged | 2 | 2018 | 30889 | 0.020 |
Why?
| | Antibodies, Monoclonal | 1 | 1992 | 1355 | 0.020 |
Why?
| | Child | 1 | 2023 | 20655 | 0.010 |
Why?
| | Breast Neoplasms | 1 | 2014 | 2132 | 0.010 |
Why?
| | Adolescent | 1 | 2017 | 20179 | 0.010 |
Why?
| | Antibody Diversity | 1 | 1992 | 16 | 0.010 |
Why?
| | Immunoglobulin Isotypes | 1 | 1992 | 34 | 0.010 |
Why?
| | Antibody Specificity | 1 | 1992 | 182 | 0.010 |
Why?
|
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Irwin's Networks
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