Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
Keywords
Last Name
Institution

David Irwin

Concepts (258)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Hemoglobins
10
2021
315
3.430
Why?
Anemia, Sickle Cell
9
2023
215
3.380
Why?
Hypoxia
10
2022
957
1.250
Why?
Altitude
4
2022
432
1.230
Why?
Hypertension, Pulmonary
7
2022
1728
1.110
Why?
Altitude Sickness
3
2016
172
1.080
Why?
Hemopexin
3
2021
13
0.970
Why?
Pulmonary Edema
2
2019
115
0.950
Why?
beta-Thalassemia
1
2023
23
0.870
Why?
Pulmonary Ventilation
1
2022
72
0.800
Why?
Haptoglobins
3
2018
47
0.760
Why?
Vascular Remodeling
3
2022
153
0.740
Why?
Rats
15
2022
4958
0.730
Why?
Capillary Permeability
4
2016
139
0.720
Why?
Beta vulgaris
1
2020
4
0.720
Why?
Pulmonary Artery
6
2022
1015
0.710
Why?
Endothelium, Vascular
3
2018
847
0.680
Why?
Oxygen
4
2022
854
0.670
Why?
Emulsions
1
2019
42
0.670
Why?
Vasodilator Agents
2
2013
302
0.660
Why?
Rats, Sprague-Dawley
10
2019
2218
0.640
Why?
Reactive Oxygen Species
2
2013
531
0.630
Why?
Blood Substitutes
2
2009
27
0.630
Why?
Animals
30
2023
31699
0.610
Why?
Lung
4
2018
3559
0.610
Why?
Fluorocarbons
1
2019
94
0.600
Why?
Microvessels
1
2018
68
0.570
Why?
Physical Exertion
1
2018
209
0.560
Why?
Carbonic Anhydrase Inhibitors
1
2016
17
0.560
Why?
Toll-Like Receptor 9
1
2017
30
0.560
Why?
Drug Delivery Systems
1
2019
296
0.550
Why?
Cerebral Veins
1
2016
15
0.550
Why?
Angiogenesis Inducing Agents
1
2016
22
0.550
Why?
Macrophages
2
2023
1261
0.540
Why?
Water
1
2019
396
0.540
Why?
Brain Edema
1
2016
60
0.540
Why?
Cerebral Arteries
1
2016
55
0.530
Why?
NF-E2-Related Factor 2
2
2013
71
0.510
Why?
Muscle Contraction
1
2018
389
0.490
Why?
Hemolysis
4
2021
146
0.490
Why?
Angiogenesis Inhibitors
1
2016
214
0.480
Why?
Atrial Natriuretic Factor
2
2005
55
0.480
Why?
Endothelial Cells
2
2013
685
0.470
Why?
Transcriptional Activation
2
2013
337
0.450
Why?
Vascular Diseases
2
2015
230
0.430
Why?
Myeloid Differentiation Factor 88
1
2013
90
0.420
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2014
249
0.410
Why?
Oxygen Consumption
2
2020
588
0.400
Why?
Mice
13
2023
14863
0.360
Why?
Lung Diseases
2
2015
701
0.330
Why?
Glutaral
1
2009
14
0.330
Why?
Phosphodiesterase 5 Inhibitors
1
2009
36
0.320
Why?
Phosphodiesterase Inhibitors
1
2009
82
0.320
Why?
Phenylpropionates
2
2019
16
0.320
Why?
Muscle, Skeletal
1
2018
1472
0.310
Why?
Disease Progression
3
2023
2380
0.310
Why?
Sulfones
1
2009
97
0.310
Why?
Pyridazines
2
2019
46
0.310
Why?
Inflammation
3
2023
2478
0.310
Why?
Vascular Resistance
3
2016
337
0.300
Why?
Endothelins
2
2018
61
0.300
Why?
Polymers
2
2009
448
0.290
Why?
Piperazines
1
2009
309
0.280
Why?
Lipid Peroxidation
3
2018
139
0.270
Why?
Nitric Oxide
3
2018
823
0.270
Why?
Disease Models, Animal
7
2022
3532
0.270
Why?
Respiration
2
2022
180
0.270
Why?
Vascular Endothelial Growth Factor A
1
2009
498
0.270
Why?
Male
16
2021
55583
0.260
Why?
Cell Nucleus
1
2009
554
0.260
Why?
Cardiac Output
3
2012
143
0.250
Why?
Muscle, Smooth, Vascular
4
2017
411
0.250
Why?
Capillary Leak Syndrome
1
2005
13
0.240
Why?
Neprilysin
1
2005
47
0.230
Why?
Heme
2
2021
52
0.230
Why?
Blood Pressure
4
2018
1538
0.230
Why?
Mice, Inbred C57BL
4
2018
4692
0.220
Why?
Oxidation-Reduction
3
2018
923
0.210
Why?
Endothelin-1
1
2005
167
0.210
Why?
Intercellular Adhesion Molecule-1
2
2015
154
0.210
Why?
Pulmonary Circulation
2
2019
407
0.210
Why?
Humans
20
2023
114662
0.200
Why?
Oxyhemoglobins
1
2021
20
0.190
Why?
Extracellular Vesicles
1
2023
83
0.190
Why?
Magnetics
1
2021
39
0.190
Why?
Scleroderma, Systemic
1
2022
96
0.190
Why?
Alternative Splicing
1
2022
187
0.180
Why?
Leukocytes, Mononuclear
1
2023
493
0.180
Why?
Muscle Proteins
1
2022
210
0.180
Why?
Metabolic Diseases
1
2021
98
0.180
Why?
Monocytes
1
2023
502
0.180
Why?
CD40 Antigens
1
2021
82
0.180
Why?
Nitrates
1
2020
72
0.170
Why?
RNA, Long Noncoding
1
2022
154
0.170
Why?
Up-Regulation
2
2013
807
0.170
Why?
Receptors, G-Protein-Coupled
1
2021
194
0.170
Why?
Histone Deacetylases
2
2012
195
0.170
Why?
Drug Evaluation, Preclinical
1
2019
161
0.160
Why?
Gadolinium
1
2019
73
0.160
Why?
Enoyl-CoA Hydratase
1
2018
9
0.160
Why?
Exercise Tolerance
1
2020
213
0.160
Why?
Lipids
2
2023
580
0.160
Why?
Antibodies
1
2021
371
0.160
Why?
Double-Blind Method
2
2020
1660
0.160
Why?
Metabolome
1
2021
282
0.160
Why?
Cell Line
2
2015
2636
0.160
Why?
Carrier Proteins
1
2022
695
0.150
Why?
Liver Diseases
1
2021
255
0.150
Why?
Blood Gas Analysis
2
2008
72
0.150
Why?
Aminophylline
1
2017
5
0.150
Why?
Proteomics
1
2023
836
0.150
Why?
Antioxidants
2
2013
530
0.140
Why?
Cell Proliferation
2
2017
2186
0.140
Why?
Lipoproteins
1
2018
159
0.140
Why?
Cells, Cultured
6
2014
3885
0.140
Why?
Mice, Knockout
3
2022
2568
0.140
Why?
Anemia, Hemolytic
1
2017
18
0.140
Why?
Acclimatization
1
2018
149
0.140
Why?
Deferoxamine
1
2016
18
0.140
Why?
Acetazolamide
1
2016
30
0.140
Why?
Dietary Supplements
1
2020
460
0.140
Why?
Niacinamide
1
2016
63
0.130
Why?
Myocytes, Cardiac
3
2022
449
0.130
Why?
Oxidative Stress
2
2012
1076
0.130
Why?
Antihypertensive Agents
1
2019
429
0.130
Why?
NF-kappa B
2
2013
641
0.130
Why?
Oligonucleotides
1
2016
137
0.130
Why?
Signal Transduction
5
2017
4512
0.130
Why?
Cardiomyopathy, Dilated
1
2018
348
0.130
Why?
Methemoglobin
2
2021
19
0.130
Why?
Vasoconstriction
1
2016
177
0.120
Why?
Indoles
1
2016
304
0.120
Why?
Hypertrophy, Right Ventricular
1
2015
141
0.110
Why?
Genomics
1
2018
635
0.110
Why?
Chloride Channels
1
2014
35
0.110
Why?
Cattle
2
2008
921
0.110
Why?
RNA, Small Interfering
3
2012
535
0.110
Why?
Catalase
1
2013
118
0.110
Why?
Cell Membrane Permeability
1
2013
83
0.110
Why?
Histone Deacetylase Inhibitors
2
2012
198
0.110
Why?
Iron
1
2015
233
0.110
Why?
Permeability
1
2013
149
0.110
Why?
Interleukin-6
1
2017
676
0.110
Why?
Ventricular Remodeling
2
2012
226
0.110
Why?
Heart Failure
2
2022
1945
0.100
Why?
Cyclic N-Oxides
1
2012
30
0.100
Why?
Infusion Pumps
1
2012
31
0.100
Why?
Spin Labels
1
2012
44
0.100
Why?
Cardiovascular Diseases
2
2021
1727
0.100
Why?
Mitochondrial Proteins
1
2014
219
0.100
Why?
Macrophages, Alveolar
1
2015
347
0.100
Why?
Superoxide Dismutase
1
2013
305
0.100
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2013
225
0.100
Why?
Gene Expression Regulation, Enzymologic
1
2012
270
0.090
Why?
Cerebellum
1
2013
200
0.090
Why?
Toll-Like Receptor 4
1
2013
287
0.090
Why?
Hydrogen Peroxide
1
2012
288
0.090
Why?
Microcirculation
2
2014
135
0.090
Why?
Blotting, Western
1
2012
1147
0.080
Why?
Pneumonia
1
2015
567
0.080
Why?
Sildenafil Citrate
1
2009
57
0.080
Why?
Female
7
2022
59493
0.080
Why?
Active Transport, Cell Nucleus
1
2009
110
0.080
Why?
NG-Nitroarginine Methyl Ester
1
2008
38
0.080
Why?
Hypoxia, Brain
1
2008
10
0.080
Why?
Purines
1
2009
159
0.080
Why?
Hemodynamics
1
2012
1012
0.070
Why?
Nitric Oxide Synthase
1
2008
209
0.070
Why?
Exercise
1
2017
1644
0.070
Why?
Norepinephrine
1
2008
201
0.070
Why?
Dogs
1
2008
334
0.070
Why?
Epinephrine
1
2008
163
0.070
Why?
Protein Isoforms
2
2022
338
0.070
Why?
RNA, Messenger
1
2013
2552
0.070
Why?
Treatment Outcome
1
2019
9088
0.070
Why?
Myocardium
1
2011
913
0.060
Why?
Stroke Volume
1
2008
504
0.060
Why?
Kidney
1
2012
1188
0.060
Why?
Stress Fibers
1
2004
16
0.060
Why?
Enzyme Inhibitors
1
2008
750
0.060
Why?
Heart Rate
1
2008
709
0.060
Why?
p38 Mitogen-Activated Protein Kinases
1
2004
260
0.060
Why?
Hypertension
1
2011
1056
0.050
Why?
Actins
1
2004
381
0.050
Why?
Lung Neoplasms
1
2014
2177
0.050
Why?
Catecholamines
1
2022
94
0.050
Why?
RNA Splicing Factors
1
2022
49
0.050
Why?
Thrombin
1
2023
139
0.050
Why?
Case-Control Studies
2
2018
3003
0.050
Why?
Lipopolysaccharides
1
2004
821
0.050
Why?
In Situ Hybridization, Fluorescence
1
2022
309
0.050
Why?
Etanercept
1
2021
51
0.050
Why?
Arrhythmias, Cardiac
1
2022
279
0.040
Why?
Ligands
1
2021
561
0.040
Why?
Intracellular Signaling Peptides and Proteins
1
2022
386
0.040
Why?
Tumor Necrosis Factor-alpha
1
2004
1139
0.040
Why?
Fatty Acids
1
2022
381
0.040
Why?
Tissue Donors
1
2021
316
0.040
Why?
Heart
1
2022
612
0.040
Why?
Cytochrome P-450 Enzyme System
1
2018
108
0.040
Why?
Guinea Pigs
1
2018
136
0.040
Why?
Ventricular Dysfunction, Right
1
2021
217
0.040
Why?
Linkage Disequilibrium
1
2018
245
0.040
Why?
Inflammation Mediators
1
2021
477
0.040
Why?
Cytoskeleton
1
2018
176
0.040
Why?
Genetics, Population
1
2018
188
0.040
Why?
Gene Regulatory Networks
1
2018
228
0.040
Why?
Proteins
1
2023
908
0.030
Why?
Heart Ventricles
2
2012
712
0.030
Why?
Sequence Analysis, RNA
1
2018
385
0.030
Why?
Mice, Inbred Strains
2
2014
396
0.030
Why?
Adenosine
1
2017
203
0.030
Why?
Mice, Transgenic
1
2021
1947
0.030
Why?
Sarcoma, Experimental
1
2014
5
0.030
Why?
Rats, Nude
1
2014
26
0.030
Why?
Drug Therapy, Combination
1
2017
951
0.030
Why?
Intravital Microscopy
1
2014
23
0.030
Why?
Models, Biological
1
2021
1620
0.030
Why?
Adult
3
2023
30544
0.030
Why?
Heterografts
1
2014
117
0.030
Why?
Coronary Vessels
1
2016
227
0.030
Why?
Genotype
1
2018
1760
0.030
Why?
Swine
1
2016
700
0.030
Why?
Transcription Factor RelA
1
2014
82
0.030
Why?
Mitochondria
1
2018
747
0.030
Why?
Cytokines
1
2021
1840
0.030
Why?
Familial Primary Pulmonary Hypertension
1
2014
190
0.030
Why?
Blood Flow Velocity
1
2014
387
0.030
Why?
Chemistry, Physical
1
2012
37
0.030
Why?
Neovascularization, Pathologic
1
2014
281
0.030
Why?
Young Adult
2
2018
10466
0.030
Why?
Fructans
1
1992
1
0.030
Why?
MicroRNAs
1
2018
600
0.030
Why?
Genes, Immunoglobulin
1
1992
26
0.030
Why?
Immunoglobulin Light Chains
1
1992
35
0.030
Why?
Gene Expression Profiling
1
2018
1518
0.030
Why?
Immunoglobulin Variable Region
1
1992
72
0.020
Why?
Immunoglobulin Heavy Chains
1
1992
72
0.020
Why?
Polymorphism, Single Nucleotide
1
2018
1879
0.020
Why?
Histone Deacetylase 6
1
2011
19
0.020
Why?
Benzamides
1
2012
169
0.020
Why?
Phenotype
1
2018
2796
0.020
Why?
Adenoviridae
1
2011
184
0.020
Why?
Regional Blood Flow
1
2012
424
0.020
Why?
RNA Interference
1
2011
433
0.020
Why?
Pyrimidines
1
2012
376
0.020
Why?
Cohort Studies
1
2018
4895
0.020
Why?
Pyridines
1
2012
425
0.020
Why?
Polymerase Chain Reaction
1
2011
993
0.020
Why?
Middle Aged
2
2018
26733
0.020
Why?
Cell Line, Tumor
1
2014
2710
0.020
Why?
Antibodies, Monoclonal
1
1992
1262
0.020
Why?
Child
1
2023
18412
0.010
Why?
Breast Neoplasms
1
2014
1862
0.010
Why?
Adolescent
1
2017
17841
0.010
Why?
Antibody Diversity
1
1992
16
0.010
Why?
Immunoglobulin Isotypes
1
1992
32
0.010
Why?
Antibody Specificity
1
1992
176
0.010
Why?
Irwin's Networks
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