Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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David Irwin

Concepts (258)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Hemoglobins
10
2021
326
3.630
Why?
Anemia, Sickle Cell
9
2023
230
3.540
Why?
Hypoxia
10
2022
963
1.320
Why?
Altitude
4
2022
422
1.300
Why?
Altitude Sickness
3
2016
163
1.150
Why?
Hypertension, Pulmonary
7
2022
1794
1.140
Why?
Hemopexin
3
2021
13
1.030
Why?
Pulmonary Edema
2
2019
125
1.000
Why?
beta-Thalassemia
1
2023
23
0.930
Why?
Pulmonary Ventilation
1
2022
71
0.850
Why?
Haptoglobins
3
2018
49
0.810
Why?
Vascular Remodeling
3
2022
152
0.790
Why?
Capillary Permeability
4
2016
140
0.770
Why?
Beta vulgaris
1
2020
4
0.770
Why?
Rats
15
2022
5392
0.750
Why?
Pulmonary Artery
6
2022
1063
0.740
Why?
Emulsions
1
2019
45
0.720
Why?
Oxygen
4
2022
854
0.710
Why?
Endothelium, Vascular
3
2018
907
0.700
Why?
Vasodilator Agents
2
2013
328
0.690
Why?
Blood Substitutes
2
2009
28
0.670
Why?
Reactive Oxygen Species
2
2013
576
0.660
Why?
Rats, Sprague-Dawley
10
2019
2478
0.650
Why?
Fluorocarbons
1
2019
105
0.630
Why?
Lung
4
2018
3664
0.630
Why?
Animals
30
2023
33381
0.620
Why?
Microvessels
1
2018
77
0.600
Why?
Physical Exertion
1
2018
222
0.600
Why?
Toll-Like Receptor 9
1
2017
30
0.590
Why?
Carbonic Anhydrase Inhibitors
1
2016
18
0.590
Why?
Cerebral Veins
1
2016
16
0.580
Why?
Drug Delivery Systems
1
2019
306
0.580
Why?
Angiogenesis Inducing Agents
1
2016
24
0.580
Why?
Brain Edema
1
2016
61
0.570
Why?
Water
1
2019
425
0.570
Why?
Macrophages
2
2023
1324
0.570
Why?
Cerebral Arteries
1
2016
56
0.570
Why?
NF-E2-Related Factor 2
2
2013
83
0.540
Why?
Atrial Natriuretic Factor
2
2005
59
0.510
Why?
Muscle Contraction
1
2018
413
0.510
Why?
Angiogenesis Inhibitors
1
2016
219
0.510
Why?
Hemolysis
4
2021
174
0.510
Why?
Endothelial Cells
2
2013
732
0.490
Why?
Transcriptional Activation
2
2013
348
0.470
Why?
Vascular Diseases
2
2015
241
0.450
Why?
Myeloid Differentiation Factor 88
1
2013
95
0.450
Why?
Hypoxia-Inducible Factor 1, alpha Subunit
3
2014
246
0.430
Why?
Oxygen Consumption
2
2020
586
0.420
Why?
Mice
13
2023
15520
0.370
Why?
Glutaral
1
2009
15
0.350
Why?
Lung Diseases
2
2015
718
0.350
Why?
Phosphodiesterase 5 Inhibitors
1
2009
36
0.350
Why?
Phenylpropionates
2
2019
17
0.340
Why?
Phosphodiesterase Inhibitors
1
2009
86
0.340
Why?
Sulfones
1
2009
98
0.330
Why?
Pyridazines
2
2019
50
0.330
Why?
Muscle, Skeletal
1
2018
1515
0.330
Why?
Disease Progression
3
2023
2490
0.320
Why?
Inflammation
3
2023
2566
0.320
Why?
Vascular Resistance
3
2016
356
0.320
Why?
Endothelins
2
2018
62
0.320
Why?
Polymers
2
2009
482
0.300
Why?
Piperazines
1
2009
316
0.290
Why?
Lipid Peroxidation
3
2018
156
0.290
Why?
Respiration
2
2022
183
0.280
Why?
Nitric Oxide
3
2018
892
0.280
Why?
Vascular Endothelial Growth Factor A
1
2009
527
0.280
Why?
Disease Models, Animal
7
2022
3730
0.280
Why?
Cell Nucleus
1
2009
580
0.270
Why?
Male
16
2021
57801
0.270
Why?
Cardiac Output
3
2012
147
0.260
Why?
Capillary Leak Syndrome
1
2005
13
0.260
Why?
Muscle, Smooth, Vascular
4
2017
454
0.260
Why?
Neprilysin
1
2005
48
0.250
Why?
Heme
2
2021
54
0.240
Why?
Blood Pressure
4
2018
1664
0.230
Why?
Oxidation-Reduction
3
2018
940
0.230
Why?
Endothelin-1
1
2005
168
0.230
Why?
Intercellular Adhesion Molecule-1
2
2015
175
0.220
Why?
Mice, Inbred C57BL
4
2018
4908
0.220
Why?
Pulmonary Circulation
2
2019
424
0.220
Why?
Oxyhemoglobins
1
2021
22
0.210
Why?
Extracellular Vesicles
1
2023
76
0.210
Why?
Magnetics
1
2021
38
0.200
Why?
Scleroderma, Systemic
1
2022
94
0.200
Why?
Humans
20
2023
118974
0.200
Why?
Alternative Splicing
1
2022
193
0.190
Why?
Leukocytes, Mononuclear
1
2023
509
0.190
Why?
Muscle Proteins
1
2022
219
0.190
Why?
Metabolic Diseases
1
2021
103
0.190
Why?
Monocytes
1
2023
513
0.190
Why?
CD40 Antigens
1
2021
80
0.190
Why?
Nitrates
1
2020
78
0.190
Why?
RNA, Long Noncoding
1
2022
161
0.180
Why?
Receptors, G-Protein-Coupled
1
2021
200
0.180
Why?
Histone Deacetylases
2
2012
198
0.180
Why?
Up-Regulation
2
2013
872
0.180
Why?
Drug Evaluation, Preclinical
1
2019
180
0.170
Why?
Gadolinium
1
2019
79
0.170
Why?
Enoyl-CoA Hydratase
1
2018
9
0.170
Why?
Lipids
2
2023
607
0.170
Why?
Exercise Tolerance
1
2020
233
0.170
Why?
Double-Blind Method
2
2020
1687
0.170
Why?
Antibodies
1
2021
392
0.170
Why?
Metabolome
1
2021
296
0.170
Why?
Cell Line
2
2015
2707
0.160
Why?
Blood Gas Analysis
2
2008
69
0.160
Why?
Liver Diseases
1
2021
282
0.160
Why?
Carrier Proteins
1
2022
726
0.160
Why?
Aminophylline
1
2017
5
0.160
Why?
Lipoproteins
1
2018
162
0.150
Why?
Proteomics
1
2023
876
0.150
Why?
Antioxidants
2
2013
564
0.150
Why?
Acclimatization
1
2018
135
0.150
Why?
Anemia, Hemolytic
1
2017
19
0.150
Why?
Deferoxamine
1
2016
17
0.150
Why?
Cell Proliferation
2
2017
2275
0.150
Why?
Acetazolamide
1
2016
28
0.150
Why?
Cells, Cultured
6
2014
4077
0.150
Why?
Mice, Knockout
3
2022
2680
0.150
Why?
Dietary Supplements
1
2020
467
0.140
Why?
Niacinamide
1
2016
70
0.140
Why?
Myocytes, Cardiac
3
2022
472
0.140
Why?
Antihypertensive Agents
1
2019
437
0.140
Why?
Oxidative Stress
2
2012
1178
0.140
Why?
NF-kappa B
2
2013
670
0.140
Why?
Oligonucleotides
1
2016
140
0.140
Why?
Methemoglobin
2
2021
22
0.130
Why?
Cardiomyopathy, Dilated
1
2018
344
0.130
Why?
Signal Transduction
5
2017
4709
0.130
Why?
Vasoconstriction
1
2016
213
0.130
Why?
Indoles
1
2016
316
0.120
Why?
Hypertrophy, Right Ventricular
1
2015
146
0.120
Why?
Chloride Channels
1
2014
35
0.120
Why?
Cattle
2
2008
978
0.120
Why?
Genomics
1
2018
706
0.120
Why?
RNA, Small Interfering
3
2012
564
0.120
Why?
Catalase
1
2013
123
0.120
Why?
Cell Membrane Permeability
1
2013
88
0.120
Why?
Histone Deacetylase Inhibitors
2
2012
200
0.110
Why?
Permeability
1
2013
156
0.110
Why?
Iron
1
2015
248
0.110
Why?
Interleukin-6
1
2017
688
0.110
Why?
Ventricular Remodeling
2
2012
229
0.110
Why?
Cyclic N-Oxides
1
2012
31
0.110
Why?
Infusion Pumps
1
2012
32
0.110
Why?
Spin Labels
1
2012
50
0.110
Why?
Heart Failure
2
2022
1969
0.110
Why?
Mitochondrial Proteins
1
2014
226
0.100
Why?
Basic Helix-Loop-Helix Transcription Factors
1
2013
219
0.100
Why?
Macrophages, Alveolar
1
2015
359
0.100
Why?
Superoxide Dismutase
1
2013
339
0.100
Why?
Cardiovascular Diseases
2
2021
1798
0.100
Why?
Gene Expression Regulation, Enzymologic
1
2012
290
0.100
Why?
Cerebellum
1
2013
203
0.100
Why?
Toll-Like Receptor 4
1
2013
330
0.100
Why?
Hydrogen Peroxide
1
2012
305
0.090
Why?
Microcirculation
2
2014
155
0.090
Why?
Blotting, Western
1
2012
1194
0.090
Why?
Sildenafil Citrate
1
2009
57
0.090
Why?
Pneumonia
1
2015
592
0.090
Why?
Active Transport, Cell Nucleus
1
2009
113
0.080
Why?
Female
7
2022
61565
0.080
Why?
NG-Nitroarginine Methyl Ester
1
2008
48
0.080
Why?
Hypoxia, Brain
1
2008
8
0.080
Why?
Purines
1
2009
161
0.080
Why?
Hemodynamics
1
2012
1004
0.080
Why?
Nitric Oxide Synthase
1
2008
225
0.080
Why?
Norepinephrine
1
2008
212
0.080
Why?
Dogs
1
2008
371
0.070
Why?
Epinephrine
1
2008
167
0.070
Why?
Exercise
1
2017
1657
0.070
Why?
Protein Isoforms
2
2022
345
0.070
Why?
RNA, Messenger
1
2013
2657
0.070
Why?
Myocardium
1
2011
970
0.070
Why?
Treatment Outcome
1
2019
9342
0.070
Why?
Stroke Volume
1
2008
513
0.070
Why?
Stress Fibers
1
2004
18
0.060
Why?
Kidney
1
2012
1353
0.060
Why?
Enzyme Inhibitors
1
2008
827
0.060
Why?
Heart Rate
1
2008
729
0.060
Why?
p38 Mitogen-Activated Protein Kinases
1
2004
285
0.060
Why?
Actins
1
2004
404
0.050
Why?
Catecholamines
1
2022
100
0.050
Why?
Hypertension
1
2011
1203
0.050
Why?
RNA Splicing Factors
1
2022
50
0.050
Why?
Thrombin
1
2023
143
0.050
Why?
Lung Neoplasms
1
2014
2220
0.050
Why?
In Situ Hybridization, Fluorescence
1
2022
310
0.050
Why?
Etanercept
1
2021
51
0.050
Why?
Lipopolysaccharides
1
2004
870
0.050
Why?
Case-Control Studies
2
2018
3171
0.050
Why?
Arrhythmias, Cardiac
1
2022
277
0.050
Why?
Ligands
1
2021
567
0.040
Why?
Intracellular Signaling Peptides and Proteins
1
2022
404
0.040
Why?
Tumor Necrosis Factor-alpha
1
2004
1171
0.040
Why?
Fatty Acids
1
2022
407
0.040
Why?
Tissue Donors
1
2021
336
0.040
Why?
Guinea Pigs
1
2018
151
0.040
Why?
Cytochrome P-450 Enzyme System
1
2018
111
0.040
Why?
Heart
1
2022
631
0.040
Why?
Linkage Disequilibrium
1
2018
273
0.040
Why?
Ventricular Dysfunction, Right
1
2021
228
0.040
Why?
Inflammation Mediators
1
2021
502
0.040
Why?
Cytoskeleton
1
2018
181
0.040
Why?
Genetics, Population
1
2018
207
0.040
Why?
Gene Regulatory Networks
1
2018
239
0.040
Why?
Proteins
1
2023
938
0.040
Why?
Sequence Analysis, RNA
1
2018
409
0.040
Why?
Heart Ventricles
2
2012
727
0.030
Why?
Mice, Inbred Strains
2
2014
405
0.030
Why?
Adenosine
1
2017
211
0.030
Why?
Mice, Transgenic
1
2021
2025
0.030
Why?
Sarcoma, Experimental
1
2014
5
0.030
Why?
Rats, Nude
1
2014
27
0.030
Why?
Intravital Microscopy
1
2014
25
0.030
Why?
Drug Therapy, Combination
1
2017
965
0.030
Why?
Heterografts
1
2014
130
0.030
Why?
Coronary Vessels
1
2016
233
0.030
Why?
Models, Biological
1
2021
1715
0.030
Why?
Adult
3
2023
31512
0.030
Why?
Transcription Factor RelA
1
2014
82
0.030
Why?
Swine
1
2016
730
0.030
Why?
Blood Flow Velocity
1
2014
327
0.030
Why?
Genotype
1
2018
1882
0.030
Why?
Familial Primary Pulmonary Hypertension
1
2014
193
0.030
Why?
Chemistry, Physical
1
2012
40
0.030
Why?
Cytokines
1
2021
1900
0.030
Why?
Mitochondria
1
2018
786
0.030
Why?
Neovascularization, Pathologic
1
2014
287
0.030
Why?
Fructans
1
1992
1
0.030
Why?
Genes, Immunoglobulin
1
1992
26
0.030
Why?
Immunoglobulin Light Chains
1
1992
35
0.030
Why?
Young Adult
2
2018
10793
0.030
Why?
Immunoglobulin Variable Region
1
1992
71
0.030
Why?
Immunoglobulin Heavy Chains
1
1992
72
0.030
Why?
MicroRNAs
1
2018
637
0.030
Why?
Gene Expression Profiling
1
2018
1597
0.030
Why?
Histone Deacetylase 6
1
2011
19
0.030
Why?
Benzamides
1
2012
176
0.020
Why?
Polymorphism, Single Nucleotide
1
2018
2062
0.020
Why?
Phenotype
1
2018
3003
0.020
Why?
Adenoviridae
1
2011
191
0.020
Why?
Regional Blood Flow
1
2012
418
0.020
Why?
RNA Interference
1
2011
460
0.020
Why?
Pyrimidines
1
2012
382
0.020
Why?
Pyridines
1
2012
440
0.020
Why?
Cohort Studies
1
2018
5116
0.020
Why?
Polymerase Chain Reaction
1
2011
1012
0.020
Why?
Cell Line, Tumor
1
2014
2851
0.020
Why?
Middle Aged
2
2018
27617
0.020
Why?
Antibodies, Monoclonal
1
1992
1284
0.020
Why?
Child
1
2023
19129
0.010
Why?
Breast Neoplasms
1
2014
1965
0.010
Why?
Adolescent
1
2017
18480
0.010
Why?
Antibody Diversity
1
1992
17
0.010
Why?
Immunoglobulin Isotypes
1
1992
32
0.010
Why?
Antibody Specificity
1
1992
184
0.010
Why?
Irwin's Networks
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