 David Irwin
Concepts (280)
Concepts are derived automatically from a person's publications.
Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.
| Name |
Number of Publications
|
Most Recent Publication
|
Publications by All Authors
|
Concept Score
|
Why?
|
|---|
| Anemia, Sickle Cell | 13 | 2025 | 270 | 5.310 |
Why?
| | Hemoglobins | 10 | 2021 | 353 | 3.230 |
Why?
| | Hemopexin | 4 | 2025 | 27 | 1.800 |
Why?
| | beta-Thalassemia | 2 | 2025 | 36 | 1.710 |
Why?
| | Hypertension, Pulmonary | 9 | 2025 | 1910 | 1.520 |
Why?
| | Hemolysis | 6 | 2025 | 206 | 1.290 |
Why?
| | Altitude Sickness | 4 | 2016 | 153 | 1.190 |
Why?
| | Exercise Tolerance | 4 | 2025 | 279 | 1.150 |
Why?
| | Altitude | 4 | 2022 | 488 | 1.110 |
Why?
| | Hypoxia | 10 | 2022 | 1112 | 1.110 |
Why?
| | Heme | 3 | 2025 | 78 | 1.100 |
Why?
| | Pulmonary Edema | 3 | 2019 | 108 | 1.080 |
Why?
| | Lung | 6 | 2025 | 4060 | 1.010 |
Why?
| | Iron | 3 | 2025 | 313 | 0.920 |
Why?
| | Muscle, Skeletal | 4 | 2025 | 1724 | 0.860 |
Why?
| | Spleen | 1 | 2025 | 514 | 0.790 |
Why?
| | Oxygen | 5 | 2024 | 931 | 0.780 |
Why?
| | Pulmonary Ventilation | 1 | 2022 | 79 | 0.760 |
Why?
| | Haptoglobins | 3 | 2018 | 53 | 0.720 |
Why?
| | Rats | 17 | 2024 | 5647 | 0.720 |
Why?
| | Capillary Permeability | 4 | 2016 | 145 | 0.690 |
Why?
| | Vascular Remodeling | 3 | 2022 | 193 | 0.690 |
Why?
| | Animals | 36 | 2025 | 36940 | 0.680 |
Why?
| | Beta vulgaris | 1 | 2020 | 12 | 0.680 |
Why?
| | Proteome | 1 | 2025 | 472 | 0.660 |
Why?
| | Pulmonary Artery | 6 | 2022 | 1086 | 0.660 |
Why?
| | Rats, Sprague-Dawley | 12 | 2024 | 2486 | 0.650 |
Why?
| | Emulsions | 1 | 2019 | 53 | 0.640 |
Why?
| | Atrial Natriuretic Factor | 3 | 2005 | 57 | 0.630 |
Why?
| | Endothelium, Vascular | 3 | 2018 | 927 | 0.630 |
Why?
| | Vasodilator Agents | 2 | 2013 | 331 | 0.620 |
Why?
| | Blood Substitutes | 2 | 2009 | 27 | 0.600 |
Why?
| | Reactive Oxygen Species | 2 | 2013 | 622 | 0.580 |
Why?
| | Fluorocarbons | 1 | 2019 | 117 | 0.560 |
Why?
| | Oxygen Consumption | 3 | 2024 | 696 | 0.540 |
Why?
| | Physical Exertion | 1 | 2018 | 215 | 0.540 |
Why?
| | Disease Models, Animal | 12 | 2025 | 4295 | 0.540 |
Why?
| | Microvessels | 1 | 2018 | 88 | 0.530 |
Why?
| | Carbonic Anhydrase Inhibitors | 1 | 2016 | 14 | 0.530 |
Why?
| | Toll-Like Receptor 9 | 1 | 2017 | 32 | 0.530 |
Why?
| | Cerebral Veins | 1 | 2016 | 16 | 0.520 |
Why?
| | Angiogenesis Inducing Agents | 1 | 2016 | 24 | 0.520 |
Why?
| | Brain Edema | 1 | 2016 | 61 | 0.510 |
Why?
| | Cerebral Arteries | 1 | 2016 | 59 | 0.510 |
Why?
| | Drug Delivery Systems | 1 | 2019 | 365 | 0.510 |
Why?
| | Water | 1 | 2019 | 460 | 0.500 |
Why?
| | Liver | 1 | 2025 | 1943 | 0.500 |
Why?
| | Mice | 17 | 2025 | 17787 | 0.480 |
Why?
| | NF-E2-Related Factor 2 | 2 | 2013 | 93 | 0.480 |
Why?
| | Macrophages | 2 | 2023 | 1547 | 0.480 |
Why?
| | Angiogenesis Inhibitors | 1 | 2016 | 229 | 0.460 |
Why?
| | Muscle Contraction | 1 | 2018 | 424 | 0.460 |
Why?
| | Exercise | 2 | 2024 | 2057 | 0.450 |
Why?
| | Endothelial Cells | 2 | 2013 | 785 | 0.440 |
Why?
| | Transcriptional Activation | 2 | 2013 | 378 | 0.420 |
Why?
| | Vascular Diseases | 2 | 2015 | 243 | 0.410 |
Why?
| | Mice, Inbred C57BL | 6 | 2025 | 5757 | 0.400 |
Why?
| | Myeloid Differentiation Factor 88 | 1 | 2013 | 99 | 0.400 |
Why?
| | Hypoxia-Inducible Factor 1, alpha Subunit | 3 | 2014 | 278 | 0.380 |
Why?
| | Glutaral | 1 | 2009 | 16 | 0.310 |
Why?
| | Lung Diseases | 2 | 2015 | 767 | 0.310 |
Why?
| | Phosphodiesterase 5 Inhibitors | 1 | 2009 | 37 | 0.310 |
Why?
| | Proteomics | 3 | 2025 | 1111 | 0.310 |
Why?
| | Phosphodiesterase Inhibitors | 1 | 2009 | 89 | 0.300 |
Why?
| | Phenylpropionates | 2 | 2019 | 19 | 0.300 |
Why?
| | Oxidative Stress | 4 | 2025 | 1317 | 0.300 |
Why?
| | Sulfones | 1 | 2009 | 110 | 0.300 |
Why?
| | Pyridazines | 2 | 2019 | 56 | 0.290 |
Why?
| | Vascular Resistance | 3 | 2016 | 375 | 0.280 |
Why?
| | Endothelins | 2 | 2018 | 65 | 0.280 |
Why?
| | Inflammation | 3 | 2023 | 2837 | 0.280 |
Why?
| | Disease Progression | 3 | 2023 | 2757 | 0.280 |
Why?
| | Polymers | 2 | 2009 | 490 | 0.280 |
Why?
| | Male | 19 | 2025 | 67762 | 0.270 |
Why?
| | Piperazines | 1 | 2009 | 350 | 0.260 |
Why?
| | Lipid Peroxidation | 3 | 2018 | 153 | 0.260 |
Why?
| | Nitric Oxide | 3 | 2018 | 915 | 0.250 |
Why?
| | Respiration | 2 | 2022 | 199 | 0.250 |
Why?
| | Vascular Endothelial Growth Factor A | 1 | 2009 | 545 | 0.250 |
Why?
| | Cell Nucleus | 1 | 2009 | 620 | 0.240 |
Why?
| | Physical Conditioning, Animal | 2 | 2025 | 257 | 0.240 |
Why?
| | Transferrin | 1 | 2025 | 47 | 0.240 |
Why?
| | Capillary Leak Syndrome | 1 | 2005 | 12 | 0.230 |
Why?
| | Cardiac Output | 3 | 2012 | 165 | 0.230 |
Why?
| | Muscle, Smooth, Vascular | 4 | 2017 | 446 | 0.230 |
Why?
| | Blood Pressure | 5 | 2018 | 1786 | 0.230 |
Why?
| | Lignans | 1 | 2024 | 13 | 0.230 |
Why?
| | Heme Oxygenase-1 | 1 | 2025 | 64 | 0.230 |
Why?
| | Glucosephosphate Dehydrogenase Deficiency | 1 | 2025 | 32 | 0.230 |
Why?
| | Neprilysin | 1 | 2005 | 47 | 0.220 |
Why?
| | Humans | 23 | 2025 | 137585 | 0.220 |
Why?
| | Glucosephosphate Dehydrogenase | 1 | 2025 | 60 | 0.220 |
Why?
| | Biphenyl Compounds | 1 | 2024 | 63 | 0.220 |
Why?
| | NAD | 1 | 2024 | 77 | 0.220 |
Why?
| | Sirtuin 3 | 1 | 2024 | 61 | 0.210 |
Why?
| | Aerosols | 1 | 2025 | 176 | 0.210 |
Why?
| | Intercellular Adhesion Molecule-1 | 2 | 2015 | 139 | 0.200 |
Why?
| | Endothelin-1 | 1 | 2005 | 182 | 0.200 |
Why?
| | Glycolysis | 1 | 2025 | 321 | 0.200 |
Why?
| | Pulmonary Circulation | 2 | 2019 | 429 | 0.200 |
Why?
| | Oxidation-Reduction | 3 | 2018 | 1060 | 0.200 |
Why?
| | Antibodies | 2 | 2021 | 410 | 0.190 |
Why?
| | Oxyhemoglobins | 1 | 2021 | 23 | 0.180 |
Why?
| | Magnetics | 1 | 2021 | 48 | 0.180 |
Why?
| | Scleroderma, Systemic | 1 | 2022 | 122 | 0.180 |
Why?
| | Muscle Proteins | 1 | 2022 | 231 | 0.170 |
Why?
| | Metabolic Diseases | 1 | 2021 | 108 | 0.170 |
Why?
| | Leukocytes, Mononuclear | 1 | 2023 | 558 | 0.170 |
Why?
| | Extracellular Vesicles | 1 | 2023 | 146 | 0.170 |
Why?
| | Monocytes | 1 | 2023 | 563 | 0.170 |
Why?
| | CD40 Antigens | 1 | 2021 | 89 | 0.170 |
Why?
| | Alternative Splicing | 1 | 2022 | 229 | 0.170 |
Why?
| | Up-Regulation | 2 | 2013 | 843 | 0.160 |
Why?
| | Nitrates | 1 | 2020 | 92 | 0.160 |
Why?
| | RNA, Long Noncoding | 1 | 2022 | 181 | 0.160 |
Why?
| | Endotoxins | 1 | 2001 | 220 | 0.160 |
Why?
| | Histone Deacetylases | 2 | 2012 | 215 | 0.160 |
Why?
| | Receptors, G-Protein-Coupled | 1 | 2021 | 220 | 0.160 |
Why?
| | Drug Evaluation, Preclinical | 1 | 2019 | 184 | 0.150 |
Why?
| | Gadolinium | 1 | 2019 | 82 | 0.150 |
Why?
| | Enoyl-CoA Hydratase | 1 | 2018 | 12 | 0.150 |
Why?
| | Cell Line | 2 | 2015 | 2847 | 0.150 |
Why?
| | Metabolome | 1 | 2021 | 350 | 0.140 |
Why?
| | Blood Gas Analysis | 2 | 2008 | 74 | 0.140 |
Why?
| | Double-Blind Method | 2 | 2020 | 1993 | 0.140 |
Why?
| | Carrier Proteins | 1 | 2022 | 771 | 0.140 |
Why?
| | Aminophylline | 1 | 2017 | 10 | 0.140 |
Why?
| | Lipids | 2 | 2023 | 672 | 0.140 |
Why?
| | Liver Diseases | 1 | 2021 | 315 | 0.140 |
Why?
| | Antioxidants | 2 | 2013 | 584 | 0.140 |
Why?
| | Lipoproteins | 1 | 2018 | 168 | 0.130 |
Why?
| | Anemia, Hemolytic | 1 | 2017 | 20 | 0.130 |
Why?
| | Cells, Cultured | 6 | 2014 | 4193 | 0.130 |
Why?
| | Deferoxamine | 1 | 2016 | 24 | 0.130 |
Why?
| | Acetazolamide | 1 | 2016 | 26 | 0.130 |
Why?
| | Cell Proliferation | 2 | 2017 | 2475 | 0.130 |
Why?
| | Acclimatization | 1 | 2018 | 177 | 0.130 |
Why?
| | Niacinamide | 1 | 2016 | 82 | 0.130 |
Why?
| | Mice, Knockout | 3 | 2022 | 3015 | 0.130 |
Why?
| | Myocytes, Cardiac | 3 | 2022 | 526 | 0.120 |
Why?
| | Dietary Supplements | 1 | 2020 | 561 | 0.120 |
Why?
| | NF-kappa B | 2 | 2013 | 691 | 0.120 |
Why?
| | Oligonucleotides | 1 | 2016 | 148 | 0.120 |
Why?
| | Antihypertensive Agents | 1 | 2019 | 494 | 0.120 |
Why?
| | Methemoglobin | 2 | 2021 | 21 | 0.120 |
Why?
| | Cardiomyopathy, Dilated | 1 | 2018 | 385 | 0.120 |
Why?
| | Signal Transduction | 5 | 2017 | 5079 | 0.110 |
Why?
| | Vasoconstriction | 1 | 2016 | 202 | 0.110 |
Why?
| | Hypertrophy, Right Ventricular | 1 | 2015 | 145 | 0.110 |
Why?
| | Chloride Channels | 1 | 2014 | 35 | 0.110 |
Why?
| | Cattle | 2 | 2008 | 984 | 0.110 |
Why?
| | Catalase | 1 | 2013 | 130 | 0.100 |
Why?
| | Cell Membrane Permeability | 1 | 2013 | 78 | 0.100 |
Why?
| | RNA, Small Interfering | 3 | 2012 | 622 | 0.100 |
Why?
| | Indoles | 1 | 2016 | 412 | 0.100 |
Why?
| | Genomics | 1 | 2018 | 795 | 0.100 |
Why?
| | Permeability | 1 | 2013 | 161 | 0.100 |
Why?
| | Histone Deacetylase Inhibitors | 2 | 2012 | 210 | 0.100 |
Why?
| | Ventricular Remodeling | 2 | 2012 | 266 | 0.100 |
Why?
| | Cyclic N-Oxides | 1 | 2012 | 29 | 0.100 |
Why?
| | Interleukin-6 | 1 | 2017 | 778 | 0.100 |
Why?
| | Infusion Pumps | 1 | 2012 | 32 | 0.100 |
Why?
| | Spin Labels | 1 | 2012 | 48 | 0.100 |
Why?
| | Heart Failure | 2 | 2022 | 2236 | 0.090 |
Why?
| | Macrophages, Alveolar | 1 | 2015 | 391 | 0.090 |
Why?
| | Basic Helix-Loop-Helix Transcription Factors | 1 | 2013 | 243 | 0.090 |
Why?
| | Gene Expression Regulation, Enzymologic | 1 | 2012 | 283 | 0.090 |
Why?
| | Mitochondrial Proteins | 1 | 2014 | 257 | 0.090 |
Why?
| | Toll-Like Receptor 4 | 1 | 2013 | 273 | 0.090 |
Why?
| | Cerebellum | 1 | 2013 | 224 | 0.090 |
Why?
| | Superoxide Dismutase | 1 | 2013 | 346 | 0.090 |
Why?
| | Cardiovascular Diseases | 2 | 2021 | 2111 | 0.090 |
Why?
| | Hydrogen Peroxide | 1 | 2012 | 328 | 0.080 |
Why?
| | Microcirculation | 2 | 2014 | 149 | 0.080 |
Why?
| | Blotting, Western | 1 | 2012 | 1226 | 0.080 |
Why?
| | Sildenafil Citrate | 1 | 2009 | 58 | 0.080 |
Why?
| | Pneumonia | 1 | 2015 | 639 | 0.080 |
Why?
| | Active Transport, Cell Nucleus | 1 | 2009 | 124 | 0.070 |
Why?
| | Hypoxia, Brain | 1 | 2008 | 8 | 0.070 |
Why?
| | NG-Nitroarginine Methyl Ester | 1 | 2008 | 48 | 0.070 |
Why?
| | Purines | 1 | 2009 | 176 | 0.070 |
Why?
| | Mice, Transgenic | 2 | 2025 | 2167 | 0.070 |
Why?
| | Epinephrine | 1 | 2008 | 139 | 0.070 |
Why?
| | Nitric Oxide Synthase | 1 | 2008 | 240 | 0.070 |
Why?
| | Female | 7 | 2022 | 73304 | 0.070 |
Why?
| | Norepinephrine | 1 | 2008 | 204 | 0.070 |
Why?
| | Hemodynamics | 1 | 2012 | 1113 | 0.070 |
Why?
| | Dogs | 1 | 2008 | 413 | 0.070 |
Why?
| | Protein Isoforms | 2 | 2022 | 404 | 0.060 |
Why?
| | Myocardium | 1 | 2011 | 1002 | 0.060 |
Why?
| | RNA, Messenger | 1 | 2013 | 2833 | 0.060 |
Why?
| | Stress Fibers | 1 | 2004 | 19 | 0.060 |
Why?
| | Stroke Volume | 1 | 2008 | 612 | 0.060 |
Why?
| | Treatment Outcome | 1 | 2019 | 10811 | 0.060 |
Why?
| | Allyl Compounds | 1 | 2024 | 21 | 0.060 |
Why?
| | Tissue Distribution | 1 | 2025 | 332 | 0.060 |
Why?
| | Enzyme Inhibitors | 1 | 2008 | 840 | 0.060 |
Why?
| | Sirtuins | 1 | 2024 | 40 | 0.060 |
Why?
| | Kidney | 1 | 2012 | 1468 | 0.060 |
Why?
| | Heart Rate | 1 | 2008 | 822 | 0.050 |
Why?
| | Phenols | 1 | 2024 | 99 | 0.050 |
Why?
| | p38 Mitogen-Activated Protein Kinases | 1 | 2004 | 283 | 0.050 |
Why?
| | Actins | 1 | 2004 | 416 | 0.050 |
Why?
| | Catecholamines | 1 | 2022 | 98 | 0.050 |
Why?
| | RNA Splicing Factors | 1 | 2022 | 53 | 0.050 |
Why?
| | Thrombin | 1 | 2023 | 152 | 0.050 |
Why?
| | Hypertension | 1 | 2011 | 1295 | 0.050 |
Why?
| | Lung Neoplasms | 1 | 2014 | 2526 | 0.040 |
Why?
| | In Situ Hybridization, Fluorescence | 1 | 2022 | 317 | 0.040 |
Why?
| | Etanercept | 1 | 2021 | 57 | 0.040 |
Why?
| | Salmonella enteritidis | 1 | 2001 | 19 | 0.040 |
Why?
| | Lipopolysaccharides | 1 | 2004 | 886 | 0.040 |
Why?
| | Case-Control Studies | 2 | 2018 | 3556 | 0.040 |
Why?
| | Arrhythmias, Cardiac | 1 | 2022 | 333 | 0.040 |
Why?
| | Tumor Necrosis Factor-alpha | 1 | 2004 | 1242 | 0.040 |
Why?
| | Ligands | 1 | 2021 | 664 | 0.040 |
Why?
| | Metabolomics | 1 | 2025 | 678 | 0.040 |
Why?
| | Erythrocytes | 1 | 2025 | 700 | 0.040 |
Why?
| | Intracellular Signaling Peptides and Proteins | 1 | 2022 | 455 | 0.040 |
Why?
| | Fatty Acids | 1 | 2022 | 443 | 0.040 |
Why?
| | Heart | 1 | 2022 | 655 | 0.040 |
Why?
| | Guinea Pigs | 1 | 2018 | 158 | 0.040 |
Why?
| | Tissue Donors | 1 | 2021 | 425 | 0.040 |
Why?
| | Linkage Disequilibrium | 1 | 2018 | 268 | 0.040 |
Why?
| | Cytochrome P-450 Enzyme System | 1 | 2018 | 155 | 0.040 |
Why?
| | Ventricular Dysfunction, Right | 1 | 2021 | 238 | 0.040 |
Why?
| | Inflammation Mediators | 1 | 2021 | 513 | 0.040 |
Why?
| | Cytoskeleton | 1 | 2018 | 191 | 0.030 |
Why?
| | Genetics, Population | 1 | 2018 | 214 | 0.030 |
Why?
| | Proteins | 1 | 2023 | 1009 | 0.030 |
Why?
| | Gene Regulatory Networks | 1 | 2018 | 305 | 0.030 |
Why?
| | Heart Ventricles | 2 | 2012 | 788 | 0.030 |
Why?
| | Mice, Inbred Strains | 2 | 2014 | 409 | 0.030 |
Why?
| | Sequence Analysis, RNA | 1 | 2018 | 452 | 0.030 |
Why?
| | Adenosine | 1 | 2017 | 225 | 0.030 |
Why?
| | Sarcoma, Experimental | 1 | 2014 | 7 | 0.030 |
Why?
| | Rats, Nude | 1 | 2014 | 26 | 0.030 |
Why?
| | Intravital Microscopy | 1 | 2014 | 25 | 0.030 |
Why?
| | Drug Therapy, Combination | 1 | 2017 | 1066 | 0.030 |
Why?
| | Heterografts | 1 | 2014 | 138 | 0.030 |
Why?
| | Models, Biological | 1 | 2021 | 1783 | 0.030 |
Why?
| | Coronary Vessels | 1 | 2016 | 248 | 0.030 |
Why?
| | Swine | 1 | 2016 | 775 | 0.030 |
Why?
| | Transcription Factor RelA | 1 | 2014 | 87 | 0.030 |
Why?
| | Genotype | 1 | 2018 | 1916 | 0.030 |
Why?
| | Familial Primary Pulmonary Hypertension | 1 | 2014 | 198 | 0.030 |
Why?
| | Blood Flow Velocity | 1 | 2014 | 413 | 0.030 |
Why?
| | Chemistry, Physical | 1 | 2012 | 37 | 0.030 |
Why?
| | Neovascularization, Pathologic | 1 | 2014 | 301 | 0.020 |
Why?
| | Cytokines | 1 | 2021 | 2085 | 0.020 |
Why?
| | Fructans | 1 | 1992 | 1 | 0.020 |
Why?
| | Genes, Immunoglobulin | 1 | 1992 | 28 | 0.020 |
Why?
| | Adult | 3 | 2023 | 37929 | 0.020 |
Why?
| | Immunoglobulin Light Chains | 1 | 1992 | 47 | 0.020 |
Why?
| | Immunoglobulin Variable Region | 1 | 1992 | 80 | 0.020 |
Why?
| | Immunoglobulin Heavy Chains | 1 | 1992 | 83 | 0.020 |
Why?
| | Mitochondria | 1 | 2018 | 948 | 0.020 |
Why?
| | MicroRNAs | 1 | 2018 | 692 | 0.020 |
Why?
| | Gene Expression Profiling | 1 | 2018 | 1774 | 0.020 |
Why?
| | Histone Deacetylase 6 | 1 | 2011 | 17 | 0.020 |
Why?
| | Young Adult | 2 | 2018 | 13209 | 0.020 |
Why?
| | Benzamides | 1 | 2012 | 216 | 0.020 |
Why?
| | Polymorphism, Single Nucleotide | 1 | 2018 | 2189 | 0.020 |
Why?
| | Adenoviridae | 1 | 2011 | 193 | 0.020 |
Why?
| | Phenotype | 1 | 2018 | 3196 | 0.020 |
Why?
| | Regional Blood Flow | 1 | 2012 | 474 | 0.020 |
Why?
| | RNA Interference | 1 | 2011 | 469 | 0.020 |
Why?
| | Pyrimidines | 1 | 2012 | 470 | 0.020 |
Why?
| | Pyridines | 1 | 2012 | 506 | 0.020 |
Why?
| | Polymerase Chain Reaction | 1 | 2011 | 1062 | 0.020 |
Why?
| | Cohort Studies | 1 | 2018 | 5742 | 0.020 |
Why?
| | Cell Line, Tumor | 1 | 2014 | 3412 | 0.020 |
Why?
| | Middle Aged | 2 | 2018 | 33479 | 0.020 |
Why?
| | Antibodies, Monoclonal | 1 | 1992 | 1430 | 0.010 |
Why?
| | Child | 1 | 2023 | 21935 | 0.010 |
Why?
| | Breast Neoplasms | 1 | 2014 | 2253 | 0.010 |
Why?
| | Adolescent | 1 | 2017 | 21513 | 0.010 |
Why?
| | Antibody Diversity | 1 | 1992 | 16 | 0.010 |
Why?
| | Immunoglobulin Isotypes | 1 | 1992 | 34 | 0.010 |
Why?
| | Antibody Specificity | 1 | 1992 | 189 | 0.010 |
Why?
|
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