Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christopher DeSouza

Concepts (406)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Cell-Derived Microparticles
17
2025
73
10.380
Why?
Endothelium, Vascular
47
2025
923
9.710
Why?
Vasodilation
31
2025
494
6.710
Why?
Endothelial Cells
19
2025
780
6.070
Why?
Endothelin-1
18
2025
181
5.790
Why?
Vasoconstriction
14
2025
202
4.020
Why?
Fibrinolysis
16
2023
143
3.340
Why?
Human Umbilical Vein Endothelial Cells
8
2025
104
3.060
Why?
Tissue Plasminogen Activator
18
2024
225
2.970
Why?
Nitric Oxide
15
2025
914
2.950
Why?
Vasodilator Agents
23
2025
333
2.910
Why?
Forearm
19
2025
120
2.860
Why?
Spinal Cord Injuries
5
2025
211
2.670
Why?
Hypertension
14
2023
1293
2.670
Why?
Sleep Deprivation
6
2021
174
2.630
Why?
Aging
40
2025
1866
2.590
Why?
Obesity
20
2025
2974
2.510
Why?
Nitric Oxide Synthase Type III
9
2025
203
2.290
Why?
Overweight
9
2018
554
2.140
Why?
MicroRNAs
7
2025
704
2.130
Why?
Acetylcholine
18
2025
186
2.030
Why?
Exercise
34
2024
2024
1.820
Why?
Middle Aged
113
2025
33355
1.750
Why?
Prehypertension
5
2015
28
1.700
Why?
Regional Blood Flow
24
2025
474
1.700
Why?
Apoptosis
16
2025
2557
1.660
Why?
Vasomotor System
2
2025
47
1.610
Why?
Blood Pressure
20
2021
1776
1.530
Why?
Cardiovascular Diseases
11
2021
2113
1.530
Why?
HIV Envelope Protein gp120
3
2019
60
1.520
Why?
Sleep
5
2021
754
1.430
Why?
Polycythemia
2
2021
21
1.430
Why?
Stem Cells
8
2012
589
1.390
Why?
Postmenopause
18
2023
361
1.260
Why?
NG-Nitroarginine Methyl Ester
3
2024
48
1.240
Why?
Nitroprusside
16
2021
69
1.230
Why?
Male
94
2025
67718
1.210
Why?
tat Gene Products, Human Immunodeficiency Virus
2
2019
24
1.200
Why?
Enzyme Inhibitors
6
2024
845
1.200
Why?
Circulating MicroRNA
2
2019
25
1.170
Why?
C-Reactive Protein
7
2015
411
1.150
Why?
Metabolic Syndrome
4
2016
354
1.140
Why?
Humans
140
2025
137514
1.090
Why?
Nebivolol
2
2017
9
1.080
Why?
Cell Movement
8
2014
972
1.070
Why?
Atherosclerosis
2
2023
415
1.060
Why?
Platelet Endothelial Cell Adhesion Molecule-1
3
2011
53
1.020
Why?
Peptides, Cyclic
7
2013
260
1.020
Why?
Caspase 3
5
2017
246
1.000
Why?
Adult
70
2025
37821
0.980
Why?
Erythritol
1
2025
2
0.960
Why?
Inflammation Mediators
5
2024
514
0.960
Why?
Microvessels
2
2025
86
0.930
Why?
Sweetening Agents
1
2025
53
0.920
Why?
Female
84
2025
73162
0.900
Why?
Vasoconstrictor Agents
6
2023
138
0.900
Why?
Aged
66
2025
23798
0.890
Why?
Cells, Cultured
10
2025
4206
0.890
Why?
Work-Life Balance
1
2024
20
0.880
Why?
Fibrin Fibrinogen Degradation Products
2
2023
84
0.860
Why?
Extracellular Vesicles
1
2025
146
0.820
Why?
Physical Endurance
16
2024
275
0.810
Why?
Goals
1
2024
168
0.800
Why?
Dietary Fats
2
2015
301
0.790
Why?
Oxidative Stress
8
2025
1307
0.780
Why?
Blood Coagulation
2
2021
254
0.750
Why?
Estrogen Replacement Therapy
9
2003
146
0.710
Why?
Vascular Diseases
1
2023
244
0.700
Why?
Biomarkers
13
2025
4172
0.680
Why?
Altitude
3
2021
482
0.670
Why?
Physical Fitness
12
2005
208
0.640
Why?
Case-Control Studies
11
2021
3546
0.640
Why?
Ascorbic Acid
3
2021
123
0.630
Why?
Acclimatization
1
2021
176
0.620
Why?
Hemodynamics
8
2021
1114
0.620
Why?
Cross-Sectional Studies
23
2023
5427
0.620
Why?
Endothelium
3
2020
122
0.590
Why?
T-Lymphocyte Subsets
2
2011
425
0.590
Why?
Dose-Response Relationship, Drug
9
2017
2066
0.580
Why?
Telomere
3
2010
280
0.580
Why?
Metoprolol
1
2017
40
0.560
Why?
HIV
1
2019
233
0.560
Why?
Hematopoietic Stem Cells
2
2011
398
0.560
Why?
Plethysmography
5
2017
106
0.550
Why?
Blood Glucose
7
2019
2183
0.540
Why?
Hyperglycemia
2
2018
346
0.540
Why?
Bradykinin
8
2015
46
0.530
Why?
Receptor, Endothelin A
2
2014
64
0.530
Why?
HIV Infections
4
2019
2830
0.520
Why?
Plasminogen Activator Inhibitor 1
7
2023
86
0.520
Why?
Stress, Physiological
2
2017
445
0.510
Why?
Cytokines
4
2020
2095
0.500
Why?
Cellular Senescence
1
2018
188
0.500
Why?
Body Mass Index
15
2017
2369
0.490
Why?
Young Adult
13
2025
13243
0.490
Why?
Nitric Oxide Synthase
4
2017
241
0.480
Why?
Interleukin-6
6
2025
778
0.470
Why?
Gender Identity
2
2006
124
0.470
Why?
Blood Pressure Determination
2
2016
156
0.460
Why?
Reactive Oxygen Species
3
2025
619
0.460
Why?
Diet, High-Fat
2
2018
248
0.450
Why?
Endothelial Progenitor Cells
1
2014
20
0.430
Why?
Interleukin-8
3
2025
269
0.430
Why?
Blood Platelets
1
2017
405
0.420
Why?
Analysis of Variance
7
2016
1324
0.420
Why?
Glucose
2
2017
1018
0.410
Why?
Brain
2
2025
2831
0.410
Why?
Adiposity
3
2016
517
0.410
Why?
Infusions, Intra-Arterial
5
2013
59
0.400
Why?
Colony-Forming Units Assay
6
2014
91
0.400
Why?
Transcription Factor RelA
2
2024
88
0.390
Why?
Blood Vessels
1
2014
188
0.390
Why?
Endothelin A Receptor Antagonists
4
2014
25
0.390
Why?
Arteries
7
2018
269
0.390
Why?
Alkalosis, Respiratory
2
2023
2
0.390
Why?
Anti-HIV Agents
1
2019
775
0.380
Why?
Inflammation
5
2025
2837
0.380
Why?
Coronary Disease
3
2007
385
0.380
Why?
Oxygen Consumption
12
2024
684
0.380
Why?
Body Composition
14
2009
668
0.380
Why?
Glucose Intolerance
1
2013
146
0.370
Why?
T-Lymphocytes
2
2010
1999
0.360
Why?
Muscle, Smooth, Vascular
5
2010
446
0.360
Why?
Abdominal Fat
1
2011
40
0.360
Why?
NF-kappa B
3
2025
694
0.360
Why?
Time Factors
10
2021
6817
0.360
Why?
Age Factors
9
2025
3301
0.350
Why?
Fatty Acids
1
2014
445
0.350
Why?
Antigens, CD34
1
2011
88
0.350
Why?
Muscle Tonus
2
2010
21
0.350
Why?
HIV Protease Inhibitors
1
2011
69
0.340
Why?
Risk Factors
14
2018
10356
0.340
Why?
Dyslipidemias
1
2012
177
0.330
Why?
Chemotaxis
1
2010
131
0.330
Why?
HIV-1
2
2019
863
0.330
Why?
Health
1
2010
84
0.320
Why?
Postprandial Period
3
2019
105
0.320
Why?
Cholesterol, LDL
1
2012
366
0.320
Why?
Heart Failure
1
2023
2222
0.320
Why?
Disease
1
2010
98
0.310
Why?
Sleep Wake Disorders
1
2013
283
0.310
Why?
Feeding Behavior
1
2015
652
0.310
Why?
Flow Cytometry
4
2019
1185
0.310
Why?
Vascular Endothelial Growth Factor A
4
2014
544
0.300
Why?
Muscarinic Agonists
1
2008
16
0.290
Why?
Phosphorylation
2
2024
1762
0.290
Why?
Fasting
4
2019
275
0.280
Why?
Reference Values
7
2016
821
0.270
Why?
omega-N-Methylarginine
3
2015
27
0.270
Why?
Endothelin Receptor Antagonists
4
2011
62
0.270
Why?
Exercise Therapy
4
2017
435
0.270
Why?
Adult Stem Cells
1
2006
41
0.260
Why?
Dinucleotide Repeats
1
2005
5
0.240
Why?
Epigenesis, Genetic
1
2010
660
0.240
Why?
Double-Blind Method
5
2021
1987
0.230
Why?
Myocardial Ischemia
1
2006
263
0.230
Why?
Hyperthermia, Induced
2
2023
116
0.230
Why?
Walking
5
2018
516
0.230
Why?
Premenopause
5
2002
125
0.220
Why?
Adipose Tissue
6
2005
624
0.220
Why?
Physiology
1
2024
15
0.220
Why?
Estrogen Receptor alpha
1
2005
144
0.220
Why?
Blood Flow Velocity
3
2012
412
0.220
Why?
Endothelin B Receptor Antagonists
2
2014
11
0.220
Why?
Quadriplegia
1
2023
12
0.220
Why?
Signal Transduction
5
2025
5096
0.220
Why?
Antihypertensive Agents
4
2013
493
0.210
Why?
Carotid Arteries
5
2003
206
0.210
Why?
Hypertrophy
2
2023
134
0.210
Why?
von Willebrand Factor
1
2023
81
0.210
Why?
Actinin
1
2023
13
0.210
Why?
Thrombophilia
1
2023
85
0.210
Why?
Running
5
2000
198
0.200
Why?
Troponin T
1
2023
67
0.200
Why?
Contraceptives, Oral
1
2002
43
0.190
Why?
Receptor, Endothelin B
2
2014
50
0.190
Why?
Career Choice
1
2024
215
0.190
Why?
Vaping
1
2023
63
0.190
Why?
Breathing Exercises
1
2021
21
0.180
Why?
Electronic Nicotine Delivery Systems
1
2023
109
0.180
Why?
Respiratory Muscles
1
2021
33
0.180
Why?
Inhalation
1
2021
29
0.180
Why?
Sex Characteristics
4
2017
766
0.180
Why?
Diet, Sodium-Restricted
1
2001
36
0.180
Why?
Colorado
6
2024
4521
0.180
Why?
South America
1
2021
59
0.180
Why?
Estradiol
1
2025
513
0.180
Why?
Peru
1
2021
59
0.180
Why?
Diet, Carbohydrate-Restricted
2
2018
37
0.170
Why?
Lymphocyte Count
2
2011
150
0.170
Why?
Endothelins
1
2021
64
0.170
Why?
Healthy Lifestyle
1
2021
34
0.170
Why?
Drug Administration Schedule
2
2016
784
0.170
Why?
Cytochromes c
2
2010
60
0.170
Why?
Fibrosis
1
2023
552
0.170
Why?
Tumor Necrosis Factor-alpha
3
2015
1242
0.170
Why?
Transforming Growth Factor beta
1
2023
480
0.170
Why?
Chemokine CXCL12
2
2010
80
0.160
Why?
Diabetes Mellitus, Type 2
3
2019
2521
0.160
Why?
Fibrinogen
2
1998
170
0.160
Why?
Piperidines
2
2013
208
0.160
Why?
Oligopeptides
2
2013
273
0.160
Why?
Physical Exertion
2
1998
212
0.160
Why?
Fever
2
2020
307
0.160
Why?
Insulin Glargine
1
2019
84
0.150
Why?
Chronic Disease
1
2025
1790
0.150
Why?
Risk Reduction Behavior
1
2021
220
0.150
Why?
Cell Proliferation
1
2006
2482
0.150
Why?
E-Selectin
1
2018
58
0.150
Why?
Hemoglobins
1
2021
356
0.150
Why?
HIV Antibodies
1
2019
62
0.150
Why?
Infusions, Intravenous
2
2011
411
0.150
Why?
Myocytes, Cardiac
1
2023
528
0.150
Why?
Brachial Artery
3
2017
200
0.150
Why?
Telomerase
2
2011
250
0.150
Why?
Phenotype
2
2021
3205
0.150
Why?
Heat-Shock Response
1
2018
78
0.140
Why?
Adrenergic beta-1 Receptor Antagonists
1
2017
11
0.140
Why?
Antioxidants
1
2021
577
0.140
Why?
Follow-Up Studies
3
2017
5139
0.140
Why?
Vascular Cell Adhesion Molecule-1
1
1997
39
0.140
Why?
Myocardial Infarction
1
2005
1045
0.140
Why?
Dietary Carbohydrates
1
2018
153
0.140
Why?
Biomedical Research
1
2024
689
0.140
Why?
Pilot Projects
1
2023
1703
0.140
Why?
Treatment Outcome
5
2021
10821
0.140
Why?
Intercellular Adhesion Molecule-1
1
1997
139
0.140
Why?
Heart
1
2021
660
0.130
Why?
Lipids
3
2009
664
0.130
Why?
Infusions, Intraosseous
1
2016
17
0.130
Why?
Prognosis
3
2018
4031
0.130
Why?
Anthropometry
2
2011
214
0.130
Why?
Enzyme Activation
1
2017
816
0.120
Why?
Triglycerides
3
2005
525
0.120
Why?
Baroreflex
3
2001
57
0.120
Why?
Insulin
2
2005
2398
0.120
Why?
Substance P
2
2008
43
0.120
Why?
Isoproterenol
2
2008
116
0.120
Why?
Blood Circulation
1
2015
41
0.120
Why?
Down-Regulation
1
2017
658
0.120
Why?
Insulin Resistance
2
2003
1198
0.110
Why?
Interleukin-18
2
2006
237
0.110
Why?
Hot Temperature
1
2017
409
0.110
Why?
Cross-Over Studies
4
2017
561
0.110
Why?
Regression Analysis
5
2011
1029
0.110
Why?
Peptides
1
2019
986
0.110
Why?
Physical Education and Training
2
2024
75
0.100
Why?
Interleukin-10
1
2015
302
0.100
Why?
Hydrocortisone
1
2015
318
0.100
Why?
Cholinergic Agonists
1
2011
6
0.090
Why?
Injections, Intravenous
1
2012
208
0.090
Why?
Blood Volume
4
1999
61
0.090
Why?
Obesity, Abdominal
1
2011
48
0.090
Why?
Waist Circumference
1
2011
143
0.090
Why?
Circadian Rhythm
1
2015
463
0.090
Why?
Plaque, Atherosclerotic
1
2011
57
0.090
Why?
Hypoglycemic Agents
1
2019
1285
0.080
Why?
Femoral Artery
2
2002
178
0.080
Why?
Vital Capacity
2
2002
309
0.080
Why?
Apoptosis Regulatory Proteins
1
2011
188
0.080
Why?
Prevalence
3
2014
2719
0.080
Why?
Plant Lectins
1
2010
8
0.080
Why?
Staurosporine
1
2010
20
0.080
Why?
Cholesterol
2
2005
413
0.080
Why?
Estrogens
2
2003
361
0.080
Why?
Cerebrovascular Circulation
2
2023
242
0.080
Why?
Granulocyte Colony-Stimulating Factor
1
2010
74
0.080
Why?
Bone Diseases, Metabolic
1
2010
62
0.080
Why?
Leg
2
2001
223
0.080
Why?
Immunoenzyme Techniques
1
2009
219
0.080
Why?
Aged, 80 and over
6
2003
7593
0.080
Why?
CD3 Complex
1
2009
106
0.080
Why?
Cell Separation
1
2010
320
0.080
Why?
Phosphatidylinositol 3-Kinases
1
2011
366
0.080
Why?
Life Style
5
2003
485
0.080
Why?
Norepinephrine
1
2009
212
0.080
Why?
Up-Regulation
1
2012
846
0.080
Why?
Proto-Oncogene Proteins c-akt
1
2011
437
0.080
Why?
Endothelin-Converting Enzymes
1
2008
10
0.070
Why?
Adolescent
6
2025
21555
0.070
Why?
Aspartic Acid Endopeptidases
1
2008
29
0.070
Why?
Metalloendopeptidases
1
2008
62
0.070
Why?
Methacholine Chloride
1
2008
52
0.070
Why?
Cell Count
1
2008
321
0.070
Why?
Calcium Channel Blockers
1
2008
168
0.070
Why?
Hemiplegia
2
1997
21
0.070
Why?
Arm
1
2007
106
0.070
Why?
Coronary Circulation
1
2007
141
0.070
Why?
Risk Assessment
1
2016
3439
0.060
Why?
Probability
1
2007
311
0.060
Why?
Lipoproteins, LDL
1
2006
119
0.060
Why?
Microscopy, Phase-Contrast
1
2005
18
0.060
Why?
Thymidine
1
2005
60
0.060
Why?
Muscle, Skeletal
3
2002
1701
0.060
Why?
DNA Methylation
1
2010
644
0.060
Why?
Weight Loss
1
2010
770
0.060
Why?
Bone Marrow Cells
1
2005
313
0.060
Why?
Anaerobic Threshold
2
2005
28
0.050
Why?
France
1
2024
33
0.050
Why?
Hypocapnia
1
2023
8
0.050
Why?
Hyperventilation
1
2023
10
0.050
Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors
1
2008
442
0.050
Why?
Thrombosis
1
2007
368
0.050
Why?
History, 21st Century
1
2024
211
0.050
Why?
Adenine
1
2005
268
0.050
Why?
Compliance
4
2008
47
0.050
Why?
Body Weight
2
2005
973
0.050
Why?
Muscarinic Antagonists
1
2003
28
0.050
Why?
Fenofibrate
1
2003
29
0.050
Why?
History, 20th Century
1
2024
324
0.050
Why?
Oxidation-Reduction
1
2006
1059
0.050
Why?
Hypertriglyceridemia
1
2003
39
0.050
Why?
Bicycling
1
2024
116
0.050
Why?
Heart Rate
4
2001
831
0.050
Why?
Sensitivity and Specificity
1
2007
1950
0.050
Why?
Polymorphism, Genetic
1
2005
658
0.050
Why?
Exercise Test
3
2005
621
0.050
Why?
Carotid Artery Diseases
1
2002
66
0.050
Why?
Progesterone
1
2003
251
0.050
Why?
Adrenergic beta-Agonists
1
2002
133
0.050
Why?
Universities
1
2024
432
0.050
Why?
Tunica Intima
4
2002
84
0.050
Why?
Carbon Dioxide
1
2023
267
0.050
Why?
Systole
1
2001
191
0.040
Why?
Heart Conduction System
1
2001
100
0.040
Why?
Ultrasonography
5
2002
750
0.040
Why?
Cardiovascular Physiological Phenomena
1
2000
43
0.040
Why?
Mexican Americans
1
2001
117
0.040
Why?
Knee
1
2000
67
0.040
Why?
Predictive Value of Tests
1
2005
2039
0.040
Why?
Hemorheology
1
2018
22
0.040
Why?
Oxygen
1
2024
943
0.040
Why?
Body Constitution
1
1998
55
0.040
Why?
Energy Intake
2
1998
478
0.040
Why?
Drug Combinations
1
2019
344
0.040
Why?
Social Class
1
2001
277
0.040
Why?
Diet, Fat-Restricted
1
2018
79
0.040
Why?
Hemostasis
1
1998
82
0.040
Why?
Plasminogen Activators
1
1997
7
0.030
Why?
Cervical Vertebrae
1
2018
135
0.030
Why?
Gait
2
1997
280
0.030
Why?
Vascular Resistance
1
1998
372
0.030
Why?
United States
1
2014
14696
0.030
Why?
Cohort Studies
1
2007
5730
0.030
Why?
Movement Disorders
1
1997
59
0.030
Why?
Cerebrovascular Disorders
1
1997
96
0.030
Why?
Chromium
1
1996
14
0.030
Why?
Weight Lifting
1
1996
34
0.030
Why?
Leukocytes, Mononuclear
1
2018
558
0.030
Why?
Gene Expression Regulation
1
2025
2615
0.030
Why?
Neoplasms
1
2010
2666
0.030
Why?
Combined Modality Therapy
1
2017
1241
0.030
Why?
Hypoxia
1
2021
1108
0.030
Why?
Antigens
1
1996
358
0.030
Why?
Swimming
3
1999
50
0.030
Why?
Melatonin
1
2015
152
0.030
Why?
Menopause
1
1997
316
0.030
Why?
Randomized Controlled Trials as Topic
1
2019
1465
0.030
Why?
Defibrillators, Implantable
1
1997
316
0.030
Why?
Brain Ischemia
1
1997
341
0.030
Why?
Tunica Media
2
2001
38
0.020
Why?
Sex Factors
1
1996
2074
0.020
Why?
Animals
3
2024
37011
0.020
Why?
Cardiac Output
2
1998
164
0.020
Why?
Prospective Studies
4
2001
7598
0.020
Why?
Bone Density
1
2010
486
0.020
Why?
Stroke Volume
2
1998
619
0.010
Why?
Hemostatics
1
2005
52
0.010
Why?
Hypolipidemic Agents
1
2003
92
0.010
Why?
Fatty Acids, Nonesterified
1
2003
159
0.010
Why?
Lipoproteins
1
2003
168
0.010
Why?
Absorptiometry, Photon
1
2002
252
0.010
Why?
Blood Viscosity
1
2001
16
0.010
Why?
Thoracic Arteries
1
2000
4
0.010
Why?
Habits
1
2001
49
0.010
Why?
Thigh
1
2000
52
0.010
Why?
Thinness
1
2000
91
0.010
Why?
Mexico
1
2001
220
0.010
Why?
Elasticity
1
2000
195
0.010
Why?
Erythrocyte Volume
1
1999
6
0.010
Why?
Plasma Volume
1
1999
19
0.010
Why?
Stress, Mechanical
1
2001
475
0.010
Why?
Femur
1
2001
263
0.010
Why?
Supine Position
1
1998
39
0.010
Why?
Posture
1
1999
185
0.010
Why?
Signal Processing, Computer-Assisted
1
1998
148
0.010
Why?
Hematocrit
1
1997
95
0.010
Why?
Rest
1
1997
122
0.010
Why?
Electric Conductivity
1
1997
95
0.010
Why?
Socioeconomic Factors
1
2001
1286
0.010
Why?
Ventricular Fibrillation
1
1997
60
0.010
Why?
Hyperlipidemias
1
1997
120
0.010
Why?
Electrodes, Implanted
1
1997
116
0.010
Why?
Diabetes Complications
1
1997
226
0.010
Why?
Equipment Design
1
1997
526
0.010
Why?
Tachycardia, Ventricular
1
1997
174
0.010
Why?
Electrocardiography
1
1998
632
0.010
Why?
Multivariate Analysis
1
1998
1524
0.010
Why?
Kinetics
1
1997
1679
0.010
Why?
Stroke
1
2002
1129
0.010
Why?
Heart Arrest
1
1997
339
0.010
Why?
Survival Rate
1
1997
1980
0.010
Why?
Length of Stay
1
1997
1210
0.010
Why?
Energy Metabolism
1
1997
895
0.010
Why?
Smoking
1
1997
1639
0.000
Why?
Retrospective Studies
1
2003
15628
0.000
Why?
DeSouza's Networks
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