Colorado PROFILES, The Colorado Clinical and Translational Sciences Institute (CCTSI)
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Christopher DeSouza

Concepts (406)

Concepts are derived automatically from a person's publications.

Concepts are listed by decreasing relevance which is based on many factors, including how many publications the person wrote about that topic, how long ago those publications were written, and how many publications other people have written on that same topic.

Name Number of Publications Most Recent Publication Publications by All Authors Concept Score Why?
Cell-Derived Microparticles
17
2025
71
10.360
Why?
Endothelium, Vascular
47
2025
926
9.680
Why?
Vasodilation
31
2025
496
6.690
Why?
Endothelial Cells
19
2025
778
6.060
Why?
Endothelin-1
18
2025
182
5.770
Why?
Vasoconstriction
14
2025
202
4.010
Why?
Fibrinolysis
16
2023
143
3.330
Why?
Human Umbilical Vein Endothelial Cells
8
2025
106
3.050
Why?
Tissue Plasminogen Activator
18
2024
225
2.960
Why?
Nitric Oxide
15
2025
915
2.940
Why?
Vasodilator Agents
23
2025
331
2.910
Why?
Forearm
19
2025
118
2.860
Why?
Hypertension
14
2023
1285
2.670
Why?
Spinal Cord Injuries
5
2025
212
2.660
Why?
Sleep Deprivation
6
2021
174
2.620
Why?
Aging
40
2025
1864
2.590
Why?
Obesity
20
2025
2982
2.500
Why?
Nitric Oxide Synthase Type III
9
2025
204
2.280
Why?
MicroRNAs
7
2025
692
2.140
Why?
Overweight
9
2018
557
2.130
Why?
Acetylcholine
18
2025
185
2.020
Why?
Exercise
34
2024
2044
1.810
Why?
Middle Aged
113
2025
33239
1.750
Why?
Regional Blood Flow
24
2025
473
1.700
Why?
Prehypertension
5
2015
28
1.700
Why?
Apoptosis
16
2025
2552
1.660
Why?
Vasomotor System
2
2025
47
1.610
Why?
Cardiovascular Diseases
11
2021
2105
1.530
Why?
Blood Pressure
20
2021
1774
1.530
Why?
HIV Envelope Protein gp120
3
2019
60
1.520
Why?
Sleep
5
2021
753
1.420
Why?
Polycythemia
2
2021
21
1.420
Why?
Stem Cells
8
2012
592
1.390
Why?
Postmenopause
18
2023
365
1.260
Why?
NG-Nitroarginine Methyl Ester
3
2024
48
1.230
Why?
Nitroprusside
16
2021
69
1.230
Why?
Male
94
2025
67330
1.220
Why?
tat Gene Products, Human Immunodeficiency Virus
2
2019
24
1.190
Why?
Enzyme Inhibitors
6
2024
839
1.190
Why?
Circulating MicroRNA
2
2019
24
1.170
Why?
C-Reactive Protein
7
2015
408
1.160
Why?
Metabolic Syndrome
4
2016
354
1.130
Why?
Humans
140
2025
136803
1.090
Why?
Nebivolol
2
2017
9
1.070
Why?
Cell Movement
8
2014
968
1.060
Why?
Atherosclerosis
2
2023
415
1.050
Why?
Platelet Endothelial Cell Adhesion Molecule-1
3
2011
52
1.020
Why?
Peptides, Cyclic
7
2013
259
1.010
Why?
Caspase 3
5
2017
246
1.000
Why?
Adult
70
2025
37643
0.980
Why?
Erythritol
1
2025
2
0.960
Why?
Inflammation Mediators
5
2024
513
0.960
Why?
Microvessels
2
2025
85
0.920
Why?
Sweetening Agents
1
2025
54
0.920
Why?
Female
84
2025
72816
0.900
Why?
Vasoconstrictor Agents
6
2023
139
0.900
Why?
Aged
66
2025
23808
0.890
Why?
Cells, Cultured
10
2025
4192
0.880
Why?
Work-Life Balance
1
2024
21
0.880
Why?
Fibrin Fibrinogen Degradation Products
2
2023
82
0.860
Why?
Extracellular Vesicles
1
2025
145
0.820
Why?
Physical Endurance
16
2024
275
0.810
Why?
Goals
1
2024
169
0.800
Why?
Dietary Fats
2
2015
304
0.790
Why?
Oxidative Stress
8
2025
1314
0.780
Why?
Blood Coagulation
2
2021
255
0.750
Why?
Estrogen Replacement Therapy
9
2003
146
0.710
Why?
Vascular Diseases
1
2023
243
0.700
Why?
Biomarkers
13
2025
4145
0.680
Why?
Altitude
3
2021
485
0.670
Why?
Physical Fitness
12
2005
208
0.640
Why?
Case-Control Studies
11
2021
3540
0.630
Why?
Acclimatization
1
2021
177
0.620
Why?
Hemodynamics
8
2021
1110
0.620
Why?
Cross-Sectional Studies
23
2023
5424
0.610
Why?
Ascorbic Acid
3
2021
176
0.590
Why?
Endothelium
3
2020
122
0.590
Why?
T-Lymphocyte Subsets
2
2011
425
0.590
Why?
Dose-Response Relationship, Drug
9
2017
2052
0.580
Why?
Telomere
3
2010
280
0.580
Why?
Metoprolol
1
2017
40
0.560
Why?
HIV
1
2019
234
0.560
Why?
Hematopoietic Stem Cells
2
2011
402
0.550
Why?
Plethysmography
5
2017
106
0.550
Why?
Blood Glucose
7
2019
2181
0.540
Why?
Hyperglycemia
2
2018
347
0.540
Why?
Bradykinin
8
2015
46
0.530
Why?
Receptor, Endothelin A
2
2014
65
0.520
Why?
HIV Infections
4
2019
2828
0.520
Why?
Stress, Physiological
2
2017
441
0.510
Why?
Plasminogen Activator Inhibitor 1
7
2023
86
0.510
Why?
Cytokines
4
2020
2084
0.500
Why?
Cellular Senescence
1
2018
187
0.500
Why?
Body Mass Index
15
2017
2375
0.490
Why?
Young Adult
13
2025
13129
0.490
Why?
Nitric Oxide Synthase
4
2017
240
0.480
Why?
Interleukin-6
6
2025
778
0.470
Why?
Gender Identity
2
2006
124
0.460
Why?
Blood Pressure Determination
2
2016
156
0.460
Why?
Reactive Oxygen Species
3
2025
621
0.460
Why?
Diet, High-Fat
2
2018
247
0.450
Why?
Endothelial Progenitor Cells
1
2014
20
0.430
Why?
Interleukin-8
3
2025
268
0.430
Why?
Brain
2
2025
2664
0.430
Why?
Blood Platelets
1
2017
407
0.420
Why?
Glucose
2
2017
1019
0.410
Why?
Analysis of Variance
7
2016
1316
0.410
Why?
Adiposity
3
2016
518
0.400
Why?
Infusions, Intra-Arterial
5
2013
59
0.400
Why?
Colony-Forming Units Assay
6
2014
91
0.400
Why?
Transcription Factor RelA
2
2024
87
0.390
Why?
Blood Vessels
1
2014
187
0.390
Why?
Endothelin A Receptor Antagonists
4
2014
26
0.390
Why?
Arteries
7
2018
269
0.390
Why?
Alkalosis, Respiratory
2
2023
2
0.380
Why?
Inflammation
5
2025
2835
0.380
Why?
Anti-HIV Agents
1
2019
775
0.380
Why?
Coronary Disease
3
2007
384
0.380
Why?
Oxygen Consumption
12
2024
695
0.380
Why?
Body Composition
14
2009
679
0.370
Why?
Glucose Intolerance
1
2013
146
0.370
Why?
T-Lymphocytes
2
2010
1993
0.360
Why?
Muscle, Smooth, Vascular
5
2010
445
0.360
Why?
NF-kappa B
3
2025
691
0.360
Why?
Time Factors
10
2021
6809
0.360
Why?
Abdominal Fat
1
2011
41
0.350
Why?
Age Factors
9
2025
3286
0.350
Why?
Fatty Acids
1
2014
442
0.350
Why?
Antigens, CD34
1
2011
88
0.350
Why?
Muscle Tonus
2
2010
21
0.350
Why?
HIV Protease Inhibitors
1
2011
69
0.340
Why?
Risk Factors
14
2018
10332
0.340
Why?
Dyslipidemias
1
2012
176
0.330
Why?
Chemotaxis
1
2010
130
0.330
Why?
HIV-1
2
2019
863
0.330
Why?
Health
1
2010
84
0.320
Why?
Cholesterol, LDL
1
2012
366
0.320
Why?
Postprandial Period
3
2019
107
0.320
Why?
Heart Failure
1
2023
2231
0.320
Why?
Disease
1
2010
98
0.310
Why?
Sleep Wake Disorders
1
2013
283
0.310
Why?
Feeding Behavior
1
2015
648
0.310
Why?
Flow Cytometry
4
2019
1180
0.310
Why?
Vascular Endothelial Growth Factor A
4
2014
543
0.300
Why?
Muscarinic Agonists
1
2008
16
0.290
Why?
Phosphorylation
2
2024
1758
0.280
Why?
Fasting
4
2019
280
0.270
Why?
Reference Values
7
2016
816
0.270
Why?
omega-N-Methylarginine
3
2015
27
0.270
Why?
Endothelin Receptor Antagonists
4
2011
62
0.270
Why?
Exercise Therapy
4
2017
436
0.270
Why?
Adult Stem Cells
1
2006
39
0.260
Why?
Dinucleotide Repeats
1
2005
5
0.240
Why?
Epigenesis, Genetic
1
2010
657
0.240
Why?
Double-Blind Method
5
2021
1982
0.230
Why?
Myocardial Ischemia
1
2006
262
0.230
Why?
Hyperthermia, Induced
2
2023
116
0.230
Why?
Walking
5
2018
523
0.230
Why?
Premenopause
5
2002
131
0.220
Why?
Adipose Tissue
6
2005
630
0.220
Why?
Physiology
1
2024
15
0.220
Why?
Blood Flow Velocity
3
2012
412
0.220
Why?
Estrogen Receptor alpha
1
2005
145
0.220
Why?
Endothelin B Receptor Antagonists
2
2014
11
0.220
Why?
Signal Transduction
5
2025
5077
0.220
Why?
Quadriplegia
1
2023
12
0.210
Why?
Antihypertensive Agents
4
2013
488
0.210
Why?
Carotid Arteries
5
2003
206
0.210
Why?
Hypertrophy
2
2023
133
0.210
Why?
von Willebrand Factor
1
2023
80
0.210
Why?
Actinin
1
2023
13
0.210
Why?
Thrombophilia
1
2023
83
0.200
Why?
Troponin T
1
2023
67
0.200
Why?
Contraceptives, Oral
1
2002
43
0.190
Why?
Running
5
2000
230
0.190
Why?
Receptor, Endothelin B
2
2014
51
0.190
Why?
Vaping
1
2023
59
0.190
Why?
Career Choice
1
2024
216
0.190
Why?
Electronic Nicotine Delivery Systems
1
2023
102
0.180
Why?
Breathing Exercises
1
2021
21
0.180
Why?
Respiratory Muscles
1
2021
33
0.180
Why?
Inhalation
1
2021
29
0.180
Why?
Sex Characteristics
4
2017
763
0.180
Why?
Colorado
6
2024
4515
0.180
Why?
Diet, Sodium-Restricted
1
2001
36
0.180
Why?
South America
1
2021
59
0.180
Why?
Estradiol
1
2025
518
0.180
Why?
Peru
1
2021
58
0.180
Why?
Diet, Carbohydrate-Restricted
2
2018
37
0.170
Why?
Lymphocyte Count
2
2011
150
0.170
Why?
Healthy Lifestyle
1
2021
34
0.170
Why?
Endothelins
1
2021
65
0.170
Why?
Drug Administration Schedule
2
2016
785
0.170
Why?
Cytochromes c
2
2010
60
0.170
Why?
Fibrosis
1
2023
552
0.170
Why?
Tumor Necrosis Factor-alpha
3
2015
1242
0.170
Why?
Transforming Growth Factor beta
1
2023
480
0.170
Why?
Chemokine CXCL12
2
2010
81
0.160
Why?
Diabetes Mellitus, Type 2
3
2019
2518
0.160
Why?
Fibrinogen
2
1998
167
0.160
Why?
Piperidines
2
2013
206
0.160
Why?
Oligopeptides
2
2013
271
0.160
Why?
Physical Exertion
2
1998
215
0.160
Why?
Fever
2
2020
306
0.160
Why?
Insulin Glargine
1
2019
84
0.150
Why?
Chronic Disease
1
2025
1786
0.150
Why?
Risk Reduction Behavior
1
2021
218
0.150
Why?
Cell Proliferation
1
2006
2476
0.150
Why?
E-Selectin
1
2018
57
0.150
Why?
Hemoglobins
1
2021
353
0.150
Why?
HIV Antibodies
1
2019
62
0.150
Why?
Infusions, Intravenous
2
2011
412
0.150
Why?
Myocytes, Cardiac
1
2023
523
0.150
Why?
Brachial Artery
3
2017
201
0.150
Why?
Telomerase
2
2011
250
0.150
Why?
Phenotype
2
2021
3189
0.150
Why?
Heat-Shock Response
1
2018
77
0.140
Why?
Adrenergic beta-1 Receptor Antagonists
1
2017
11
0.140
Why?
Follow-Up Studies
3
2017
5106
0.140
Why?
Vascular Cell Adhesion Molecule-1
1
1997
39
0.140
Why?
Antioxidants
1
2021
584
0.140
Why?
Myocardial Infarction
1
2005
1044
0.140
Why?
Biomedical Research
1
2024
688
0.140
Why?
Dietary Carbohydrates
1
2018
155
0.140
Why?
Pilot Projects
1
2023
1693
0.140
Why?
Treatment Outcome
5
2021
10748
0.140
Why?
Intercellular Adhesion Molecule-1
1
1997
139
0.140
Why?
Heart
1
2021
653
0.130
Why?
Lipids
3
2009
665
0.130
Why?
Infusions, Intraosseous
1
2016
17
0.130
Why?
Prognosis
3
2018
4013
0.130
Why?
Anthropometry
2
2011
213
0.130
Why?
Enzyme Activation
1
2017
810
0.120
Why?
Triglycerides
3
2005
524
0.120
Why?
Baroreflex
3
2001
57
0.120
Why?
Substance P
2
2008
36
0.120
Why?
Insulin
2
2005
2406
0.120
Why?
Isoproterenol
2
2008
113
0.120
Why?
Blood Circulation
1
2015
41
0.120
Why?
Down-Regulation
1
2017
656
0.120
Why?
Insulin Resistance
2
2003
1203
0.110
Why?
Interleukin-18
2
2006
236
0.110
Why?
Hot Temperature
1
2017
391
0.110
Why?
Cross-Over Studies
4
2017
562
0.110
Why?
Peptides
1
2019
981
0.110
Why?
Regression Analysis
5
2011
1022
0.110
Why?
Physical Education and Training
2
2024
76
0.100
Why?
Interleukin-10
1
2015
302
0.100
Why?
Hydrocortisone
1
2015
322
0.100
Why?
Cholinergic Agonists
1
2011
6
0.090
Why?
Injections, Intravenous
1
2012
207
0.090
Why?
Blood Volume
4
1999
61
0.090
Why?
Obesity, Abdominal
1
2011
48
0.090
Why?
Waist Circumference
1
2011
143
0.090
Why?
Plaque, Atherosclerotic
1
2011
57
0.090
Why?
Circadian Rhythm
1
2015
469
0.090
Why?
Hypoglycemic Agents
1
2019
1283
0.080
Why?
Femoral Artery
2
2002
179
0.080
Why?
Apoptosis Regulatory Proteins
1
2011
188
0.080
Why?
Vital Capacity
2
2002
311
0.080
Why?
Prevalence
3
2014
2710
0.080
Why?
Plant Lectins
1
2010
8
0.080
Why?
Staurosporine
1
2010
20
0.080
Why?
Cholesterol
2
2005
410
0.080
Why?
Cerebrovascular Circulation
2
2023
241
0.080
Why?
Granulocyte Colony-Stimulating Factor
1
2010
74
0.080
Why?
Estrogens
2
2003
368
0.080
Why?
Bone Diseases, Metabolic
1
2010
62
0.080
Why?
Immunoenzyme Techniques
1
2009
219
0.080
Why?
Aged, 80 and over
6
2003
7593
0.080
Why?
Cell Separation
1
2010
317
0.080
Why?
CD3 Complex
1
2009
106
0.080
Why?
Leg
2
2001
236
0.080
Why?
Phosphatidylinositol 3-Kinases
1
2011
366
0.080
Why?
Life Style
5
2003
487
0.080
Why?
Norepinephrine
1
2009
204
0.080
Why?
Up-Regulation
1
2012
844
0.080
Why?
Proto-Oncogene Proteins c-akt
1
2011
437
0.080
Why?
Endothelin-Converting Enzymes
1
2008
10
0.070
Why?
Adolescent
6
2025
21385
0.070
Why?
Aspartic Acid Endopeptidases
1
2008
29
0.070
Why?
Metalloendopeptidases
1
2008
62
0.070
Why?
Methacholine Chloride
1
2008
52
0.070
Why?
Cell Count
1
2008
323
0.070
Why?
Calcium Channel Blockers
1
2008
167
0.070
Why?
Hemiplegia
2
1997
21
0.070
Why?
Arm
1
2007
104
0.070
Why?
Coronary Circulation
1
2007
140
0.070
Why?
Risk Assessment
1
2016
3434
0.060
Why?
Probability
1
2007
304
0.060
Why?
Lipoproteins, LDL
1
2006
116
0.060
Why?
Microscopy, Phase-Contrast
1
2005
18
0.060
Why?
Thymidine
1
2005
60
0.060
Why?
Muscle, Skeletal
3
2002
1710
0.060
Why?
DNA Methylation
1
2010
640
0.060
Why?
Bone Marrow Cells
1
2005
316
0.050
Why?
Weight Loss
1
2010
776
0.050
Why?
Anaerobic Threshold
2
2005
28
0.050
Why?
France
1
2024
33
0.050
Why?
Hypocapnia
1
2023
8
0.050
Why?
Hyperventilation
1
2023
10
0.050
Why?
Hydroxymethylglutaryl-CoA Reductase Inhibitors
1
2008
443
0.050
Why?
Thrombosis
1
2007
366
0.050
Why?
History, 21st Century
1
2024
212
0.050
Why?
Adenine
1
2005
270
0.050
Why?
Compliance
4
2008
49
0.050
Why?
Fenofibrate
1
2003
28
0.050
Why?
Body Weight
2
2005
985
0.050
Why?
Muscarinic Antagonists
1
2003
29
0.050
Why?
History, 20th Century
1
2024
324
0.050
Why?
Oxidation-Reduction
1
2006
1059
0.050
Why?
Bicycling
1
2024
114
0.050
Why?
Hypertriglyceridemia
1
2003
39
0.050
Why?
Heart Rate
4
2001
820
0.050
Why?
Sensitivity and Specificity
1
2007
1936
0.050
Why?
Polymorphism, Genetic
1
2005
659
0.050
Why?
Exercise Test
3
2005
625
0.050
Why?
Carotid Artery Diseases
1
2002
64
0.050
Why?
Adrenergic beta-Agonists
1
2002
133
0.050
Why?
Progesterone
1
2003
254
0.050
Why?
Universities
1
2024
433
0.050
Why?
Tunica Intima
4
2002
84
0.050
Why?
Carbon Dioxide
1
2023
267
0.050
Why?
Systole
1
2001
189
0.040
Why?
Heart Conduction System
1
2001
99
0.040
Why?
Ultrasonography
5
2002
752
0.040
Why?
Cardiovascular Physiological Phenomena
1
2000
42
0.040
Why?
Mexican Americans
1
2001
120
0.040
Why?
Knee
1
2000
68
0.040
Why?
Predictive Value of Tests
1
2005
2022
0.040
Why?
Hemorheology
1
2018
22
0.040
Why?
Oxygen
1
2024
930
0.040
Why?
Body Constitution
1
1998
55
0.040
Why?
Energy Intake
2
1998
484
0.040
Why?
Drug Combinations
1
2019
343
0.040
Why?
Social Class
1
2001
281
0.040
Why?
Diet, Fat-Restricted
1
2018
79
0.040
Why?
Hemostasis
1
1998
82
0.040
Why?
Plasminogen Activators
1
1997
7
0.030
Why?
Cervical Vertebrae
1
2018
135
0.030
Why?
Vascular Resistance
1
1998
372
0.030
Why?
Gait
2
1997
296
0.030
Why?
United States
1
2014
14691
0.030
Why?
Cohort Studies
1
2007
5704
0.030
Why?
Movement Disorders
1
1997
58
0.030
Why?
Cerebrovascular Disorders
1
1997
96
0.030
Why?
Chromium
1
1996
15
0.030
Why?
Weight Lifting
1
1996
33
0.030
Why?
Leukocytes, Mononuclear
1
2018
558
0.030
Why?
Gene Expression Regulation
1
2025
2605
0.030
Why?
Neoplasms
1
2010
2643
0.030
Why?
Combined Modality Therapy
1
2017
1231
0.030
Why?
Hypoxia
1
2021
1112
0.030
Why?
Antigens
1
1996
358
0.030
Why?
Swimming
3
1999
51
0.030
Why?
Melatonin
1
2015
150
0.030
Why?
Menopause
1
1997
319
0.030
Why?
Randomized Controlled Trials as Topic
1
2019
1462
0.030
Why?
Defibrillators, Implantable
1
1997
315
0.030
Why?
Brain Ischemia
1
1997
340
0.030
Why?
Tunica Media
2
2001
38
0.020
Why?
Sex Factors
1
1996
2064
0.020
Why?
Animals
3
2024
36850
0.020
Why?
Cardiac Output
2
1998
164
0.020
Why?
Prospective Studies
4
2001
7573
0.020
Why?
Bone Density
1
2010
487
0.020
Why?
Stroke Volume
2
1998
612
0.010
Why?
Hemostatics
1
2005
52
0.010
Why?
Hypolipidemic Agents
1
2003
92
0.010
Why?
Fatty Acids, Nonesterified
1
2003
159
0.010
Why?
Lipoproteins
1
2003
168
0.010
Why?
Absorptiometry, Photon
1
2002
254
0.010
Why?
Blood Viscosity
1
2001
17
0.010
Why?
Thoracic Arteries
1
2000
4
0.010
Why?
Habits
1
2001
49
0.010
Why?
Thigh
1
2000
48
0.010
Why?
Thinness
1
2000
91
0.010
Why?
Mexico
1
2001
225
0.010
Why?
Elasticity
1
2000
197
0.010
Why?
Erythrocyte Volume
1
1999
6
0.010
Why?
Plasma Volume
1
1999
19
0.010
Why?
Femur
1
2001
254
0.010
Why?
Stress, Mechanical
1
2001
481
0.010
Why?
Supine Position
1
1998
39
0.010
Why?
Posture
1
1999
186
0.010
Why?
Signal Processing, Computer-Assisted
1
1998
143
0.010
Why?
Hematocrit
1
1997
96
0.010
Why?
Rest
1
1997
121
0.010
Why?
Electric Conductivity
1
1997
86
0.010
Why?
Socioeconomic Factors
1
2001
1282
0.010
Why?
Ventricular Fibrillation
1
1997
60
0.010
Why?
Electrodes, Implanted
1
1997
109
0.010
Why?
Hyperlipidemias
1
1997
120
0.010
Why?
Diabetes Complications
1
1997
226
0.010
Why?
Equipment Design
1
1997
521
0.010
Why?
Tachycardia, Ventricular
1
1997
175
0.010
Why?
Electrocardiography
1
1998
629
0.010
Why?
Multivariate Analysis
1
1998
1507
0.010
Why?
Kinetics
1
1997
1664
0.010
Why?
Stroke
1
2002
1133
0.010
Why?
Heart Arrest
1
1997
338
0.010
Why?
Survival Rate
1
1997
1964
0.010
Why?
Length of Stay
1
1997
1205
0.010
Why?
Energy Metabolism
1
1997
919
0.010
Why?
Smoking
1
1997
1620
0.000
Why?
Retrospective Studies
1
2003
15510
0.000
Why?
DeSouza's Networks
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