 Hydroxymethylglutaryl-CoA Reductase Inhibitors
"Hydroxymethylglutaryl-CoA Reductase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds that inhibit HMG-CoA reductases. They have been shown to directly lower cholesterol synthesis.
| Descriptor ID |
D019161
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| MeSH Number(s) |
D27.505.519.186.071.202.370 D27.505.519.389.370 D27.505.954.557.500.202.370
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| Concept/Terms |
Hydroxymethylglutaryl-CoA Reductase Inhibitors- Hydroxymethylglutaryl-CoA Reductase Inhibitors
- Hydroxymethylglutaryl CoA Reductase Inhibitors
- Inhibitors, Hydroxymethylglutaryl-CoA Reductase
- Reductase Inhibitors, Hydroxymethylglutaryl-CoA
- Inhibitors, HMG-CoA Reductase
- Inhibitors, HMG CoA Reductase
- Reductase Inhibitors, HMG-CoA
- HMG-CoA Reductase Inhibitors
- HMG CoA Reductase Inhibitors
- Statins, HMG-CoA
- HMG-CoA Statins
- Statins, HMG CoA
- Inhibitors, Hydroxymethylglutaryl-CoA
- Hydroxymethylglutaryl-CoA Inhibitors
- Inhibitors, Hydroxymethylglutaryl CoA
- Statins
- Inhibitors, Hydroxymethylglutaryl-Coenzyme A
- Hydroxymethylglutaryl-Coenzyme A Inhibitors
- Inhibitors, Hydroxymethylglutaryl Coenzyme A
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Below are MeSH descriptors whose meaning is more general than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
Below are MeSH descriptors whose meaning is more specific than "Hydroxymethylglutaryl-CoA Reductase Inhibitors".
This graph shows the total number of publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in this website by year, and whether "Hydroxymethylglutaryl-CoA Reductase Inhibitors" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1997 | 1 | 0 | 1 | | 1998 | 1 | 0 | 1 | | 1999 | 2 | 0 | 2 | | 2000 | 1 | 0 | 1 | | 2001 | 2 | 1 | 3 | | 2002 | 4 | 3 | 7 | | 2003 | 7 | 0 | 7 | | 2004 | 4 | 1 | 5 | | 2005 | 11 | 0 | 11 | | 2006 | 10 | 5 | 15 | | 2007 | 13 | 5 | 18 | | 2008 | 8 | 7 | 15 | | 2009 | 10 | 5 | 15 | | 2010 | 8 | 5 | 13 | | 2011 | 6 | 6 | 12 | | 2012 | 5 | 2 | 7 | | 2013 | 8 | 0 | 8 | | 2014 | 10 | 2 | 12 | | 2015 | 17 | 4 | 21 | | 2016 | 11 | 3 | 14 | | 2017 | 11 | 8 | 19 | | 2018 | 14 | 6 | 20 | | 2019 | 10 | 10 | 20 | | 2020 | 14 | 3 | 17 | | 2021 | 10 | 2 | 12 | | 2022 | 17 | 0 | 17 | | 2023 | 11 | 2 | 13 | | 2024 | 7 | 5 | 12 | | 2025 | 4 | 5 | 9 |
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Below are the most recent publications written about "Hydroxymethylglutaryl-CoA Reductase Inhibitors" by people in Profiles.
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Ngai H, Olson S, Curci J, Kazmers A, Shames M, Tsai S, Blackwelder W, Matsumura JS, Baxter BT, Terrin M, Albrecht JS. A comparison of women and men with small abdominal aortic aneurysms. Br J Surg. 2025 Sep 02; 112(9).
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Skuli SJ, Bakayoko A, Kruidenier M, Manning B, Pammer P, Salimov A, Riley O, Brake-Sillá G, Dopkin D, Bowman M, Martinez-Gutierrez LN, Anderson CC, Reisz JA, Buono R, Paul M, Saland E, Liccardo F, DeVine A, Wong S, Xu JP, Nee E, Hausler R, Boettcher S, Sebti SM, Lai C, Maxwell KN, Sarry JE, Fruman DA, D'Alessandro A, Mesaros C, Keith B, Simon MC, Sung PJ, Wertheim G, Skuli N, Bowman RL, Matthews A, Carroll M. Chemoresistance of TP53 mutant acute myeloid leukemia requires the mevalonate byproduct, geranylgeranyl pyrophosphate, for induction of an adaptive stress response. Leukemia. 2025 Sep; 39(9):2087-2098.
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Erlandson KM, McKhann A, Kitch DW, Palella FJ, Ellis RJ, Ances BM, Zanni MV, Diggs MR, Chu SM, Currier JS, Bloomfield GS, Malvestutto CD, Fichtenbaum CJ, Aberg JA, Koletar SL, Presti RM, Hatlen TJ, Skiest DJ, Douglas PS, Ribaudo HJ, Grinspoon SK. No evidence of a detrimental effect of pitavastatin on neurocognitive function among people with HIV. AIDS. 2025 Nov 01; 39(13):1913-1919.
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Worledge EA, Billups SJ, Titus OJ, Saseen JJ. Achievement of low-density lipoprotein cholesterol thresholds in very high-risk atherosclerotic cardiovascular disease. J Clin Lipidol. 2025 Jul-Aug; 19(4):860-868.
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Bittner V, Linnebur SA, Dixon DL, Forman DE, Green AR, Jacobson TA, Orkaby AR, Saseen JJ, Virani SS. Managing Hypercholesterolemia in Adults Older Than 75?years Without a History of Atherosclerotic Cardiovascular Disease: An Expert Clinical Consensus From the National Lipid Association and the American Geriatrics Society. J Am Geriatr Soc. 2025 Jun; 73(6):1674-1696.
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Bittner V, Linnebur SA, Dixon DL, Forman DE, Green AR, Jacobson TA, Orkaby AR, Saseen JJ, Virani SS. Managing hypercholesterolemia in adults older than 75 years without a history of atherosclerotic cardiovascular disease: An Expert Clinical Consensus from the National Lipid Association and the American Geriatrics Society. J Clin Lipidol. 2025 Mar-Apr; 19(2):215-237.
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Fstkchian AK, Lowe RN, Saseen JJ. Statin therapy prescribing in atherosclerotic cardiovascular disease patients with chronic kidney disease. J Am Pharm Assoc (2003). 2025 Jul-Aug; 65(4):102395.
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Erlandson KM, Umbleja T, Ribaudo HJ, Schrack JA, Overton ET, Fichtenbaum CJ, Fitch KV, Roa JC, Diggs MR, Wood K, Zanni MV, Bloomfield GS, Malvestutto C, Aberg JA, Rodriguez-Barradas MC, Morones RG, Breaux K, Douglas PS, Grinspoon SK, Brown TT. Pitavastatin Is Well-Tolerated With no Detrimental Effects on Physical Function. Clin Infect Dis. 2025 02 24; 80(2):425-433.
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Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, Dunbar RL, Ketchum SB, Tardif JC, Martens FMAC, Ballantyne CM, Szarek M, Mason RP. Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. J Am Heart Assoc. 2025 Mar 04; 14(5):e038656.
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Kao DP, Martin JL, Aquilante CL, Shalowitz EL, Leyba K, Kudron E, Reusch JEB, Regensteiner JG. Sex-differences in reporting of statin-associated diabetes mellitus to the US Food and Drug Administration. BMJ Open Diabetes Res Care. 2024 Dec 05; 12(6).
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