 Melatonin
"Melatonin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.
| Descriptor ID |
D008550
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| MeSH Number(s) |
D03.633.100.473.914.481 D06.472.506
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Melatonin".
Below are MeSH descriptors whose meaning is more specific than "Melatonin".
This graph shows the total number of publications written about "Melatonin" by people in this website by year, and whether "Melatonin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 | | 1999 | 0 | 2 | 2 | | 2000 | 2 | 2 | 4 | | 2001 | 0 | 2 | 2 | | 2002 | 0 | 1 | 1 | | 2003 | 4 | 1 | 5 | | 2004 | 4 | 2 | 6 | | 2005 | 4 | 2 | 6 | | 2006 | 3 | 3 | 6 | | 2007 | 0 | 3 | 3 | | 2008 | 0 | 1 | 1 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 3 | 3 | | 2011 | 2 | 2 | 4 | | 2012 | 2 | 0 | 2 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 5 | 6 | | 2015 | 3 | 4 | 7 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 3 | 4 | | 2018 | 0 | 5 | 5 | | 2019 | 3 | 1 | 4 | | 2020 | 1 | 2 | 3 | | 2021 | 4 | 0 | 4 | | 2022 | 5 | 0 | 5 | | 2023 | 6 | 0 | 6 | | 2024 | 2 | 0 | 2 | | 2025 | 2 | 7 | 9 |
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Below are the most recent publications written about "Melatonin" by people in Profiles.
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Hartstein LE, Akacem LD, Wright KP, LeBourgeois MK. The Relationship Between Circadian Phase and Sleep Timing in Preschool-Aged Children. J Biol Rhythms. 2026 Feb; 41(1):139-145.
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Reis DJ, Huang JB, Bahraini NH. The relationship between sleep and circadian-sleep phase angles based on dim light melatonin onset predicted from light and activity data. J Clin Sleep Med. 2025 Aug 01; 21(8):1349-1361.
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Simon SL, Cooper E, Bernard A, Bowen AE, Holtman S, Brinton JT, Hawkins SMM, Cree MG, Nadeau KJ, Wright KP. Evening Chronotype Is Associated With Daytime Impairment and Differential Sleep and Circadian Response to a Sleep Extension Manipulation in Short Sleeping Adolescents. J Sleep Res. 2026 Feb; 35(1):e70062.
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Castaneda JM, Leonhard A, Spece LJ, Duan KI, Palen BN, Chen JA, Li YI, Zeliadt S, Josey K, Feemster LC, Au DH, Donovan LM. Incidence and Predictors of Long-Term Hypnotic Receipt among Patients with Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2025 Jun; 22(6):863-871.
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Reiter PD, Schwab-Daugherty E, Daugherty J, Hohenstein E, Cripe P. Melatonin Use and Association With Delirium Burden Among Children Admitted to an Intensive Care Unit Within a Large Pediatric Healthcare Organization. J Pharm Pract. 2026 Feb; 39(1):40-46.
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Stritzel WJ, Levy C, Ravenel JR, Strnad HK, Osman M, Prévost ED, Root DH, Reuter JD, Sloan AM, Spencer RL. Red Light Sensitivity of Non-image and Image Forming Visual Systems of Laboratory Rodents: Circadian Disruption and Behavioral Detection. J Neurosci. 2025 05 14; 45(20).
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Holtman S, Cooper E, Brinton JT, Bowen AE, Hawkins S, Cree MG, Nadeau KJ, Wright KP, Simon SL. Changes in circadian timing following a 1-week in-home sleep extension manipulation in habitually short-sleeping adolescents. Sleep. 2025 Feb 10; 48(2).
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Reis C, Pilz LK, Paiva T, Hidalgo MP, Wright KP. Sleep and circadian rhythms in delayed sleep-wake phase disorder: Phenotypic differences between patients with and without comorbid depression. J Sleep Res. 2025 Aug; 34(4):e14437.
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Hartstein LE, Wright KP, Diniz Behn C, Stowe SR, LeBourgeois MK. The Circadian Response to Evening Light Spectra in Early Childhood: Preliminary Insights. J Biol Rhythms. 2025 04; 40(2):181-193.
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Murray JM, Stone JE, Abbott SM, Bjorvatn B, Burgess HJ, Cajochen C, Dekker JJ, Duffy JF, Epstein LJ, Garbazza C, Harsh J, Klerman EB, Lane JM, Lockley SW, Pavlova MK, Quan SF, Reid KJ, Scheer FAJL, Sletten TL, Wright KP, Zee PC, Phillips AJK, Czeisler CA, Rajaratnam SMW. A Protocol to Determine Circadian Phase by At-Home Salivary Dim Light Melatonin Onset Assessment. J Pineal Res. 2024 Aug; 76(5):e12994.
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