 Superoxide Dismutase-1
"Superoxide Dismutase-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A superoxide dismutase (SOD1) that requires copper and zinc ions for its activity to destroy SUPEROXIDE FREE RADICALS within the CYTOPLASM. Mutations in the SOD1 gene are associated with AMYOTROPHIC LATERAL SCLEROSIS-1.
| Descriptor ID |
D000072105
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| MeSH Number(s) |
D08.811.682.881.500
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| Concept/Terms |
Superoxide Dismutase-1- Superoxide Dismutase-1
- Cuprozinc Superoxide Dismutase
- Superoxide Dismutase, Cuprozinc
- Superoxide Dismutase 1
- Cu-Zn Superoxide Dismutase
- Cu Zn Superoxide Dismutase
- Superoxide Dismutase, Cu-Zn
- SOD-1 Protein
- SOD 1 Protein
- SOD1 Protein
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Below are MeSH descriptors whose meaning is more general than "Superoxide Dismutase-1".
Below are MeSH descriptors whose meaning is more specific than "Superoxide Dismutase-1".
This graph shows the total number of publications written about "Superoxide Dismutase-1" by people in this website by year, and whether "Superoxide Dismutase-1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 2002 | 0 | 1 | 1 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2012 | 0 | 1 | 1 | | 2017 | 0 | 1 | 1 | | 2018 | 2 | 0 | 2 | | 2021 | 1 | 1 | 2 |
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Below are the most recent publications written about "Superoxide Dismutase-1" by people in Profiles.
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Genç B, Jara JH, Sanchez SS, Lagrimas AKB, Gözütok Ö, Koçak N, Zhu Y, Hande Özdinler P. Upper motor neurons are a target for gene therapy and UCHL1 is necessary and sufficient to improve cellular integrity of diseased upper motor neurons. Gene Ther. 2022 04; 29(3-4):178-192.
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Wang X, Zhang H, Sapio R, Yang J, Wong J, Zhang X, Guo JY, Pine S, Van Remmen H, Li H, White E, Liu C, Kiledjian M, Pestov DG, Steven Zheng XF. SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer. Nat Commun. 2021 04 15; 12(1):2259.
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Alemasov NA, Ivanisenko NV, Taneja B, Taneja V, Ramachandran S, Ivanisenko VA. Improved regression model to predict an impact of SOD1 mutations on ALS patients survival time based on analysis of hydrogen bond stability. J Mol Graph Model. 2019 01; 86:247-255.
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Kiskinis E, Kralj JM, Zou P, Weinstein EN, Zhang H, Tsioras K, Wiskow O, Ortega JA, Eggan K, Cohen AE. All-Optical Electrophysiology for High-Throughput Functional Characterization of a Human iPSC-Derived Motor Neuron Model of ALS. Stem Cell Reports. 2018 06 05; 10(6):1991-2004.
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Alemasov NA, Ivanisenko NV, Ramachandran S, Ivanisenko VA. Molecular mechanisms underlying the impact of mutations in SOD1 on its conformational properties associated with amyotrophic lateral sclerosis as revealed with molecular modelling. BMC Struct Biol. 2018 02 05; 18(Suppl 1):1.
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Agarwal A, Wu PH, Hughes EG, Fukaya M, Tischfield MA, Langseth AJ, Wirtz D, Bergles DE. Transient Opening of the Mitochondrial Permeability Transition Pore Induces Microdomain Calcium Transients in Astrocyte Processes. Neuron. 2017 Feb 08; 93(3):587-605.e7.
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Beqollari D, Romberg CF, Dobrowolny G, Martini M, Voss AA, Musarò A, Bannister RA. Progressive impairment of CaV1.1 function in the skeletal muscle of mice expressing a mutant type 1 Cu/Zn superoxide dismutase (G93A) linked to amyotrophic lateral sclerosis. Skelet Muscle. 2016; 6:24.
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Du Y, Navab M, Shen M, Hill J, Pakbin P, Sioutas C, Hsiai TK, Li R. Ambient ultrafine particles reduce endothelial nitric oxide production via S-glutathionylation of eNOS. Biochem Biophys Res Commun. 2013 Jul 05; 436(3):462-6.
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Zheng J, Payne K, Taggart JE, Jiang H, Lind SE, Ding WQ. Trolox enhances curcumin's cytotoxicity through induction of oxidative stress. Cell Physiol Biochem. 2012; 29(3-4):353-60.
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Maron JL, Johnson KL, Parkin C, Iyer L, Davis JM, Bianchi DW. Cord blood genomic analysis highlights the role of redox balance. Free Radic Biol Med. 2010 Sep 15; 49(6):992-6.
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