 Telomerase
"Telomerase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An essential ribonucleoprotein reverse transcriptase that adds telomeric DNA to the ends of eukaryotic CHROMOSOMES.
| Descriptor ID |
D019098
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| MeSH Number(s) |
D08.811.913.696.445.308.300.750.750 D12.776.157.687.613 D12.776.157.725.500.921 D12.776.660.720.613 D12.776.664.962.500.921
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| Concept/Terms |
Telomerase- Telomerase
- Telomerase Reverse Transcriptase
- Reverse Transcriptase, Telomerase
- Transcriptase, Telomerase Reverse
Telomerase Catalytic Subunit- Telomerase Catalytic Subunit
- Catalytic Subunit, Telomerase
- Subunit, Telomerase Catalytic
- Telomerase Reverse Transcriptase Catalytic Subunit
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Below are MeSH descriptors whose meaning is more general than "Telomerase".
Below are MeSH descriptors whose meaning is more specific than "Telomerase".
This graph shows the total number of publications written about "Telomerase" by people in this website by year, and whether "Telomerase" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1995 | 0 | 1 | 1 | | 1996 | 2 | 0 | 2 | | 1997 | 11 | 0 | 11 | | 1998 | 6 | 1 | 7 | | 1999 | 6 | 0 | 6 | | 2000 | 8 | 1 | 9 | | 2001 | 2 | 0 | 2 | | 2002 | 5 | 2 | 7 | | 2003 | 8 | 1 | 9 | | 2004 | 3 | 7 | 10 | | 2005 | 5 | 0 | 5 | | 2006 | 3 | 0 | 3 | | 2007 | 2 | 1 | 3 | | 2008 | 5 | 4 | 9 | | 2009 | 0 | 3 | 3 | | 2010 | 6 | 2 | 8 | | 2011 | 4 | 2 | 6 | | 2012 | 4 | 0 | 4 | | 2013 | 8 | 2 | 10 | | 2014 | 6 | 4 | 10 | | 2015 | 7 | 0 | 7 | | 2016 | 2 | 0 | 2 | | 2017 | 2 | 0 | 2 | | 2019 | 2 | 2 | 4 | | 2020 | 5 | 0 | 5 | | 2021 | 4 | 2 | 6 | | 2022 | 2 | 1 | 3 | | 2023 | 3 | 0 | 3 | | 2024 | 2 | 4 | 6 | | 2025 | 2 | 1 | 3 |
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Below are the most recent publications written about "Telomerase" by people in Profiles.
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Flynn A, Pattison AD, Balachander S, Boehm E, Bowen B, Dwight T, Rossello FJ, Hofmann O, Martelotto L, Zethoven M, Kirschner LS, Else T, Fishbein L, Gill AJ, Tischler AS, Giordano T, Prodanov T, Noble JR, Reddel RR, Trainer AH, Ghayee HK, Bourdeau I, Elston M, Ishak D, Ngeow Yuen Yie J, Hicks RJ, Crona J, ?kerstr?m T, St?lberg P, Dahia P, Grimmond S, Clifton-Bligh R, Pacak K, Tothill RW. Multi-omic analysis of SDHB-deficient pheochromocytomas and paragangliomas identifies metastasis and treatment-related molecular profiles. Nat Commun. 2025 Mar 17; 16(1):2632.
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Moeller-McCoy CA, Wieser TA, Lubin JW, Gillespie AE, Ramirez JA, Paschini M, Wuttke DS, Lundblad V. The canonical RPA complex interacts with Est3 to regulate yeast telomerase activity. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2419309122.
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Forino NM, Woo JZ, Zaug AJ, Jimenez AG, Edelson E, Cech TR, Rouskin S, Stone MD. Telomerase RNA structural heterogeneity in living human cells detected by DMS-MaPseq. Nat Commun. 2025 Jan 22; 16(1):925.
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Massaad E, Smith WJ, Bradley J, Esposito E, Gupta M, Burns E, Burns R, Velarde JK, Berglar IK, Gupta R, Martinez-Lage M, Dietrich J, Lennerz JK, Dunn GP, Jones PS, Choi BD, Kim AE, Frosch M, Barker FG, Curry WT, Carter BS, Nahed BV, Cahill DP, Shankar GM. Radical surgical resection with molecular margins is associated with improved survival in IDH wild-type glioblastoma. Neuro Oncol. 2024 Sep 05; 26(9):1660-1669.
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Johnson K, Seidel JM, Cech TR. Small molecule telomerase inhibitors are also potent inhibitors of telomeric C-strand synthesis. RNA. 2024 08 16; 30(9):1213-1226.
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Lee YH, Hass EP, Campodonico W, Lee YK, Lasda E, Shah JS, Rinn JL, Hwang T. Massively parallel dissection of RNA in RNA-protein interactions in vivo. Nucleic Acids Res. 2024 Jun 10; 52(10):e48.
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Cai SW, Takai H, Zaug AJ, Dilgen TC, Cech TR, Walz T, de Lange T. POT1 recruits and regulates CST-Pola/primase at human telomeres. Cell. 2024 Jul 11; 187(14):3638-3651.e18.
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Pershad Y, Mack T, Poisner H, Jakubek YA, Stilp AM, Mitchell BD, Lewis JP, Boerwinkle E, Loos RJF, Chami N, Wang Z, Barnes K, Pankratz N, Fornage M, Redline S, Psaty BM, Bis JC, Shojaie A, Silverman EK, Cho MH, Yun JH, DeMeo D, Levy D, Johnson AD, Mathias RA, Taub MA, Arnett D, North KE, Raffield LM, Carson AP, Doyle MF, Rich SS, Rotter JI, Guo X, Cox NJ, Roden DM, Franceschini N, Desai P, Reiner AP, Auer PL, Scheet PA, Jaiswal S, Weinstock JS, Bick AG. Determinants of mosaic chromosomal alteration fitness. Nat Commun. 2024 May 07; 15(1):3800.
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Arnoult N, Cech TR. Telomerase misbehaves after a breakup. Science. 2024 02 16; 383(6684):702-703.
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Hentschel J, Badst?bner M, Choi J, Bagshaw CR, Lapointe CP, Wang J, Jansson LI, Puglisi JD, Stone MD. Real-time detection of human telomerase DNA synthesis by multiplexed single-molecule FRET. Biophys J. 2023 09 05; 122(17):3447-3457.
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