 Acetylcholine
"Acetylcholine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A neurotransmitter found at neuromuscular junctions, autonomic ganglia, parasympathetic effector junctions, a subset of sympathetic effector junctions, and at many sites in the central nervous system.
| Descriptor ID |
D000109
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| MeSH Number(s) |
D02.092.211.111
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| Concept/Terms |
Acetylcholine- Acetylcholine
- 2-(Acetyloxy)-N,N,N-trimethylethanaminium
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Below are MeSH descriptors whose meaning is more general than "Acetylcholine".
Below are MeSH descriptors whose meaning is more specific than "Acetylcholine".
This graph shows the total number of publications written about "Acetylcholine" by people in this website by year, and whether "Acetylcholine" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1996 | 0 | 2 | 2 | | 1997 | 0 | 2 | 2 | | 1998 | 2 | 1 | 3 | | 1999 | 0 | 6 | 6 | | 2000 | 0 | 2 | 2 | | 2001 | 1 | 3 | 4 | | 2002 | 1 | 6 | 7 | | 2003 | 1 | 1 | 2 | | 2004 | 1 | 2 | 3 | | 2005 | 1 | 3 | 4 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2008 | 0 | 2 | 2 | | 2009 | 3 | 6 | 9 | | 2010 | 1 | 5 | 6 | | 2011 | 3 | 7 | 10 | | 2012 | 1 | 6 | 7 | | 2013 | 1 | 2 | 3 | | 2015 | 2 | 3 | 5 | | 2016 | 0 | 6 | 6 | | 2017 | 0 | 4 | 4 | | 2018 | 0 | 2 | 2 | | 2019 | 2 | 4 | 6 | | 2020 | 1 | 2 | 3 | | 2021 | 0 | 7 | 7 | | 2022 | 0 | 1 | 1 | | 2023 | 0 | 2 | 2 | | 2024 | 0 | 1 | 1 | | 2025 | 0 | 2 | 2 |
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Below are the most recent publications written about "Acetylcholine" by people in Profiles.
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Garcia VP, Fandl HK, Wegerson KN, Berry AR, Ruzzene ST, Greiner JJ, Stockelman KA, Dow CA, Park AJ, Stauffer BL, DeSouza CA. Elevated circulating endothelial cell-derived microvesicles: a biomarker of endothelial vasomotor dysfunction in adults with obesity. J Appl Physiol (1985). 2025 May 01; 138(5):1143-1149.
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Saternos HC, Forero KV, Meqdad MA, Buqaileh R, Sunderman CL, Gallagher G, Messer WS, Mohieldin AM, Mucci CA, Kumariya S, Osman IA, Burkett JP, AbouAlaiwi WA. Muscarinic acetylcholine receptor 3 localized to primary endothelial cilia regulates blood pressure and cognition. Sci Rep. 2025 Jan 30; 15(1):3745.
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Nielsen BE, Ford CP. Reduced striatal M4-cholinergic signaling following dopamine loss contributes to parkinsonian and l-DOPA-induced dyskinetic behaviors. Sci Adv. 2024 Nov 22; 10(47):eadp6301.
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Freeberg KA, Craighead DH, Heinbockel TC, Rossman MJ, Jackman RA, Jankowski LR, Ludwig KR, Chonchol M, Bailey EF, Seals DR. Time-efficient, high-resistance inspiratory muscle strength training increases cerebrovascular reactivity in midlife and older adults. Am J Physiol Heart Circ Physiol. 2023 11 01; 325(5):H1059-H1068.
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Wenner MM, Welti LM, Dow CA, Greiner JJ, Stauffer BL, DeSouza CA. Aerobic exercise training reduces ET-1-mediated vasoconstriction and improves endothelium-dependent vasodilation in postmenopausal women. Am J Physiol Heart Circ Physiol. 2023 06 01; 324(6):H732-H738.
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Brunt VE, Greenberg NT, Sapinsley ZJ, Casso AG, Richey JJ, VanDongen NS, Gioscia-Ryan RA, Ziemba BP, Neilson AP, Davy KP, Seals DR. Suppression of trimethylamine N-oxide with DMB mitigates vascular dysfunction, exercise intolerance, and frailty associated with a Western-style diet in mice. J Appl Physiol (1985). 2022 10 01; 133(4):798-813.
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Mineur YS, Mose TN, Vanopdenbosch L, Etherington IM, Ogbejesi C, Islam A, Pineda CM, Crouse RB, Zhou W, Thompson DC, Bentham MP, Picciotto MR. Hippocampal acetylcholine modulates stress-related behaviors independent of specific cholinergic inputs. Mol Psychiatry. 2022 03; 27(3):1829-1838.
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Stone RM, Ainslie PN, Tremblay JC, Akins JD, MacLeod DB, Tymko MM, DeSouza CA, Bain AR. GLOBAL REACH 2018: intra-arterial vitamin C improves endothelial-dependent vasodilatory function in humans at high altitude. J Physiol. 2022 03; 600(6):1373-1383.
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Stockelman KA, Bain AR, Goulding A, DeSouza NM, Rahaman C, Maly L, Greiner JJ, Stauffer BL, DeSouza CA. Negative Influence of Insufficient Sleep on Endothelial Vasodilator and Fibrinolytic Function in Hypertensive Adults. Hypertension. 2021 12; 78(6):1829-1840.
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Sardar D, Lozzi B, Woo J, Huang TW, Cvetkovic C, Creighton CJ, Krencik R, Deneen B. Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds. Int J Mol Sci. 2021 Apr 12; 22(8).
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