 Cross-Over Studies
"Cross-Over Studies" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Studies comparing two or more treatments or interventions in which the subjects or patients, upon completion of the course of one treatment, are switched to another. In the case of two treatments, A and B, half the subjects are randomly allocated to receive these in the order A, B and half to receive them in the order B, A. A criticism of this design is that effects of the first treatment may carry over into the period when the second is given. (Last, A Dictionary of Epidemiology, 2d ed)
| Descriptor ID |
D018592
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| MeSH Number(s) |
E05.318.780.150 N05.715.360.780.150 N06.850.520.445.150
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| Concept/Terms |
Cross-Over Studies- Cross-Over Studies
- Cross Over Studies
- Cross-Over Study
- Studies, Cross-Over
- Study, Cross-Over
- Crossover Studies
- Crossover Study
- Studies, Crossover
- Study, Crossover
- Cross-Over Trials
- Cross Over Trials
- Trial, Cross-Over
- Trials, Cross-Over
- Crossover Trials
- Trial, Crossover
- Trials, Crossover
Cross-Over Design- Cross-Over Design
- Cross Over Design
- Cross-Over Designs
- Design, Cross-Over
- Designs, Cross-Over
- Crossover Design
- Crossover Designs
- Design, Crossover
- Designs, Crossover
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Below are MeSH descriptors whose meaning is more general than "Cross-Over Studies".
Below are MeSH descriptors whose meaning is more specific than "Cross-Over Studies".
This graph shows the total number of publications written about "Cross-Over Studies" by people in this website by year, and whether "Cross-Over Studies" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 | | 1997 | 0 | 4 | 4 | | 1998 | 0 | 3 | 3 | | 1999 | 0 | 4 | 4 | | 2000 | 0 | 5 | 5 | | 2001 | 0 | 3 | 3 | | 2002 | 0 | 6 | 6 | | 2003 | 0 | 5 | 5 | | 2004 | 0 | 12 | 12 | | 2005 | 0 | 10 | 10 | | 2006 | 0 | 11 | 11 | | 2007 | 0 | 7 | 7 | | 2008 | 0 | 12 | 12 | | 2009 | 0 | 10 | 10 | | 2010 | 0 | 10 | 10 | | 2011 | 0 | 15 | 15 | | 2012 | 0 | 15 | 15 | | 2013 | 0 | 20 | 20 | | 2014 | 0 | 22 | 22 | | 2015 | 0 | 18 | 18 | | 2016 | 0 | 20 | 20 | | 2017 | 1 | 23 | 24 | | 2018 | 1 | 16 | 17 | | 2019 | 0 | 23 | 23 | | 2020 | 1 | 16 | 17 | | 2021 | 0 | 21 | 21 | | 2022 | 0 | 16 | 16 | | 2023 | 2 | 10 | 12 | | 2024 | 12 | 9 | 21 | | 2025 | 0 | 28 | 28 | | 2026 | 0 | 23 | 23 |
To return to the timeline, click here.
Below are the most recent publications written about "Cross-Over Studies" by people in Profiles.
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Kuhrt N, Parthasarathi A, Bisno DI, Josey K, Gandhi P, Rua M, Robinson D, Wo E, Visaria A, Gomez L, Akhabue E, Guglin M, Setoguchi S. Ambient Temperature and Heart Failure Hospitalizations in Older Adults in the US. JAMA Netw Open. 2026 Oct 01; 9(10):e2641051.
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Soonhuae C, Lapierre-Nguyen S, Mariani V, Ferreira LF, Kim JS, Handberg EM, Ruzieh M, Pepine CJ, Christou DD. Vascular effects of dietary nitrate supplementation in older adults with coronary artery disease: A randomized, placebo-controlled, crossover pilot trial. Exp Gerontol. 2026 Nov; 225:113343.
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Mitchell JJ, Abdenur JE, de Boer F, Boyer M, Breilyn MS, Couce ML, De Leon DD, Derks TG, El-Gharbawy A, Haijer-Schreuder AB, Loechner K, Longo N, Lund AM, Olmos MAM, McCandless SE, de Oliveira BM, Mount M, Muschol N, Pytlak K, Radhakrishnan K, Riba-Wolman R, Rodriguez-Buritica DF, La Rosa A, Rossi A, Saavedra H, Santer R, Shayota B, Smit GPA, Moura De Souza CF, van der Klauw MM, Weinstein DA, Wolfsdorf JI, Blake A, Grimm AA, Mitragotri D, Rahman S, Turner-Bowker DM, Collis R. Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa. J Inherit Metab Dis. 2026 Sep; 49(5):e70241.
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Ni W, Agewall S, Benson L, Breitner S, Nobile F, Savarese G, Schneider A, Ljungman P. Cold Spells, Heat Waves, and Nonoptimal Air Temperature and Risk of Heart Failure Hospitalization in Sweden. J Am Coll Cardiol. 2026 Sep 01; 88(9):1016-1029.
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Oh S, Mitchell CM, White K, Lu M, Hu X, Trost J, Charleston JB, Wu B, Schlechter H, Thomas L, Sabie A, Chung JT, Rebholz CM, Juraschek SP, Mueller NT, Wang NY, Selvin E, Maruthur NM, Miller ER, Yeh HC, Appel LJ, Pilla SJ. Rationale, design, and methods of the dietary approaches to stop hypertension for diabetes (DASH4D) controlled feeding trial. Contemp Clin Trials. 2026 Oct; 169:108436.
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Kwak EJ, Zersen K, Tucker C, Lavender C, Talbot C, Gustafson D, Hendry-Hofer T, Hall K. Intramuscular tranexamic acid results in lower peak plasma concentrations but comparable systemic absorption to intravenous administration in healthy dogs. Am J Vet Res. 2026 Nov 01; 87(11).
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Yang L, Gabriel N, Tang S, Cater L, Blackburn H, Page RL, Saba S, Hernandez I. Case-Crossover Analysis of Short-Term Particulate Matter and Health Outcomes in Patients With Atrial Fibrillation. J Am Heart Assoc. 2026 08 04; 15(15):e046917.
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Schwab F, Patel KV, Mekhail N, Langhorst M, Heros RD, Gentile J, Costandi S, Moore G, Gilmore C, Manion S, Chakravarthy K, Meyer SC, Bundy JV, Tate JL, Sanders R, Vaid S, Szentirmai O, Goree J, Patel VV, Lehmen J, Desai MJ, Pope JE, Giuffrida A, Hayek S, Virk SS, Paicius R, Klemme WR, Gilligan C. Restorative neurostimulation outcomes for mechanical chronic low back pain: delayed-start crossover from optimal medical management and 2-year treatment longitudinal analyses from the RESTORE randomized controlled trial. Spine J. 2026 Nov; 26(11):2118-2133.
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Zuraikat FM, Scaccia SE, Cochran JA, Cheng B, Diaz KM, Creasy SA, Melanson EL, Shen W, Aggarwal B, Jelic S, St-Onge MP. Prolonged Short Sleep and Its Effect on Body Weight and Composition : A Pooled Analysis of Randomized Trials. Ann Intern Med. 2026 Aug; 179(8):1085-1093.
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Nowak-Wegrzyn A, Fleischer DM, Lieberman JA, Golden DBK, Kilroy E, Slatko G, Rance K, Greenhawt M. Pharmacokinetics and pharmacodynamics of AQST-109 sublingual film in oral allergy syndrome: A phase 2 study. Ann Allergy Asthma Immunol. 2026 Nov; 137(5):641-649.e3.
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