 Inhibitor of Growth Protein 1
"Inhibitor of Growth Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.
| Descriptor ID |
D000076023
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| MeSH Number(s) |
D12.644.360.368 D12.776.476.383 D12.776.624.776.503 D12.776.660.494
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Inhibitor of Growth Protein 1".
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This graph shows the total number of publications written about "Inhibitor of Growth Protein 1" by people in this website by year, and whether "Inhibitor of Growth Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Inhibitor of Growth Protein 1" by people in Profiles.
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Pe?a PV, Hom RA, Hung T, Lin H, Kuo AJ, Wong RP, Subach OM, Champagne KS, Zhao R, Verkhusha VV, Li G, Gozani O, Kutateladze TG. Histone H3K4me3 binding is required for the DNA repair and apoptotic activities of ING1 tumor suppressor. J Mol Biol. 2008 Jul 04; 380(2):303-12.
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