 Proliferating Cell Nuclear Antigen
"Proliferating Cell Nuclear Antigen" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.
| Descriptor ID |
D018809
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| MeSH Number(s) |
D12.776.660.740 D23.050.290.750 D23.101.140.600
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Proliferating Cell Nuclear Antigen".
Below are MeSH descriptors whose meaning is more specific than "Proliferating Cell Nuclear Antigen".
This graph shows the total number of publications written about "Proliferating Cell Nuclear Antigen" by people in this website by year, and whether "Proliferating Cell Nuclear Antigen" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 | | 1996 | 1 | 1 | 2 | | 2000 | 0 | 3 | 3 | | 2001 | 0 | 1 | 1 | | 2002 | 1 | 1 | 2 | | 2003 | 0 | 1 | 1 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 5 | 5 | | 2006 | 2 | 1 | 3 | | 2007 | 1 | 1 | 2 | | 2008 | 0 | 3 | 3 | | 2010 | 0 | 1 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proliferating Cell Nuclear Antigen" by people in Profiles.
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Liu J, Chaves-Arquero B, Wei P, Tencer AH, Ruiz-Albor A, Zhang G, Blanco FJ, Kutateladze TG. Molecular insight into the PCNA-binding mode of FBH1. Structure. 2023 05 04; 31(5):511-517.e3.
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Allen BG, Bhatia SK, Buatti JM, Brandt KE, Lindholm KE, Button AM, Szweda LI, Smith BJ, Spitz DR, Fath MA. Ketogenic diets enhance oxidative stress and radio-chemo-therapy responses in lung cancer xenografts. Clin Cancer Res. 2013 Jul 15; 19(14):3905-13.
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Mizuno S, Farkas L, Al Husseini A, Farkas D, Gomez-Arroyo J, Kraskauskas D, Nicolls MR, Cool CD, Bogaard HJ, Voelkel NF. Severe pulmonary arterial hypertension induced by SU5416 and ovalbumin immunization. Am J Respir Cell Mol Biol. 2012 Nov; 47(5):679-87.
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Lee JH, Hanaoka M, Kitaguchi Y, Kraskauskas D, Shapiro L, Voelkel NF, Taraseviciene-Stewart L. Imbalance of apoptosis and cell proliferation contributes to the development and persistence of emphysema. Lung. 2012 Feb; 190(1):69-82.
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Wakui S, Motohashi M, Muto T, Takahashi H, Hano H, Jutabha P, Anzai N, Wempe MF, Endou H. Sex-associated difference in estrogen receptor ? expression in N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric cancers in rats. Comp Med. 2011 Oct; 61(5):412-8.
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Yang G, Hinson MD, Bordner JE, Lin QS, Fernando AP, La P, Wright CJ, Dennery PA. Silencing hyperoxia-induced C/EBPa in neonatal mice improves lung architecture via enhanced proliferation of alveolar epithelial cells. Am J Physiol Lung Cell Mol Physiol. 2011 Aug; 301(2):L187-96.
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Velmurugan B, Singh RP, Kaul N, Agarwal R, Agarwal C. Dietary feeding of grape seed extract prevents intestinal tumorigenesis in APCmin/+ mice. Neoplasia. 2010 Jan; 12(1):95-102.
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Ge XN, Chu HW, Minor MN, Case SR, Bosch DG, Martin RJ. Roflumilast increases Clara cell secretory protein in cigarette smoke-exposed mice. COPD. 2009 Jun; 6(3):185-91.
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Stuart SA, Wang JY. Ionizing radiation induces ATM-independent degradation of p21Cip1 in transformed cells. J Biol Chem. 2009 May 29; 284(22):15061-70.
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Deep G, Raina K, Singh RP, Oberlies NH, Kroll DJ, Agarwal R. Isosilibinin inhibits advanced human prostate cancer growth in athymic nude mice: comparison with silymarin and silibinin. Int J Cancer. 2008 Dec 15; 123(12):2750-8.
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