 Silent Information Regulator Proteins, Saccharomyces cerevisiae
"Silent Information Regulator Proteins, Saccharomyces cerevisiae" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A set of nuclear proteins in SACCHAROMYCES CEREVISIAE that are required for the transcriptional repression of the silent mating type loci. They mediate the formation of silenced CHROMATIN and repress both transcription and recombination at other loci as well. They are comprised of 4 non-homologous, interacting proteins, Sir1p, Sir2p, Sir3p, and Sir4p. Sir2p, an NAD-dependent HISTONE DEACETYLASE, is the founding member of the family of SIRTUINS.
| Descriptor ID |
D038281
|
| MeSH Number(s) |
D12.776.354.750.750 D12.776.660.820
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Silent Information Regulator Proteins, Saccharomyces cerevisiae".
Below are MeSH descriptors whose meaning is more specific than "Silent Information Regulator Proteins, Saccharomyces cerevisiae".
This graph shows the total number of publications written about "Silent Information Regulator Proteins, Saccharomyces cerevisiae" by people in this website by year, and whether "Silent Information Regulator Proteins, Saccharomyces cerevisiae" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2009 | 0 | 2 | 2 | | 2013 | 1 | 1 | 2 |
To return to the timeline, click here.
Below are the most recent publications written about "Silent Information Regulator Proteins, Saccharomyces cerevisiae" by people in Profiles.
-
Zukowski A, Johnson AM. The interplay of histone H2B ubiquitination with budding and fission yeast heterochromatin. Curr Genet. 2018 Aug; 64(4):799-806.
-
Zukowski A, Al-Afaleq NO, Duncan ED, Yao T, Johnson AM. Recruitment and allosteric stimulation of a histone-deubiquitinating enzyme during heterochromatin assembly. J Biol Chem. 2018 02 16; 293(7):2498-2509.
-
Chen H, Xue J, Churikov D, Hass EP, Shi S, Lemon LD, Luciano P, Bertuch AA, Zappulla DC, G?li V, Wu J, Lei M. Structural Insights into Yeast Telomerase Recruitment to Telomeres. Cell. 2018 01 11; 172(1-2):331-343.e13.
-
Hass EP, Zappulla DC. The Ku subunit of telomerase binds Sir4 to recruit telomerase to lengthen telomeres in S. cerevisiae. Elife. 2015 Jul 28; 4.
-
Johnson A, Wu R, Peetz M, Gygi SP, Moazed D. Heterochromatic gene silencing by activator interference and a transcription elongation barrier. J Biol Chem. 2013 Oct 04; 288(40):28771-82.
-
Wang F, Li G, Altaf M, Lu C, Currie MA, Johnson A, Moazed D. Heterochromatin protein Sir3 induces contacts between the amino terminus of histone H4 and nucleosomal DNA. Proc Natl Acad Sci U S A. 2013 May 21; 110(21):8495-500.
-
Wang H, Mayhew D, Chen X, Johnston M, Mitra RD. Calling Cards enable multiplexed identification of the genomic targets of DNA-binding proteins. Genome Res. 2011 May; 21(5):748-55.
-
Johnson A, Li G, Sikorski TW, Buratowski S, Woodcock CL, Moazed D. Reconstitution of heterochromatin-dependent transcriptional gene silencing. Mol Cell. 2009 Sep 24; 35(6):769-81.
-
Sinha M, Watanabe S, Johnson A, Moazed D, Peterson CL. Recombinational repair within heterochromatin requires ATP-dependent chromatin remodeling. Cell. 2009 Sep 18; 138(6):1109-21.
-
Tamburini BA, Carson JJ, Linger JG, Tyler JK. Dominant mutants of the Saccharomyces cerevisiae ASF1 histone chaperone bypass the need for CAF-1 in transcriptional silencing by altering histone and Sir protein recruitment. Genetics. 2006 Jun; 173(2):599-610.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|