 Lim Kinases
"Lim Kinases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Serine protein kinases involved in the regulation of ACTIN polymerization and MICROTUBULE disassembly. Their activity is regulated by phosphorylation of a threonine residue within the activation loop by intracellular signaling kinases such as P21-ACTIVATED KINASES and by RHO KINASE.
| Descriptor ID |
D054461
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| MeSH Number(s) |
D08.811.913.696.620.682.700.542 D12.644.360.390 D12.776.476.396 D12.776.512.124
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| Concept/Terms |
Lim Kinases- Lim Kinases
- Kinases, Lim
- LIM Motif-Containing Protein Kinases
- LIM Motif Containing Protein Kinases
- LIM-Kinase
- LIM Kinase
- Kinase, LIM
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Below are MeSH descriptors whose meaning is more general than "Lim Kinases".
Below are MeSH descriptors whose meaning is more specific than "Lim Kinases".
This graph shows the total number of publications written about "Lim Kinases" by people in this website by year, and whether "Lim Kinases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lim Kinases" by people in Profiles.
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Rajgor D, Sanderson TM, Amici M, Collingridge GL, Hanley JG. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018 06 01; 37(11).
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Caruso P, Dunmore BJ, Schlosser K, Schoors S, Dos Santos C, Perez-Iratxeta C, Lavoie JR, Zhang H, Long L, Flockton AR, Frid MG, Upton PD, D'Alessandro A, Hadinnapola C, Kiskin FN, Taha M, Hurst LA, Ormiston ML, Hata A, Stenmark KR, Carmeliet P, Stewart DJ, Morrell NW. Identification of MicroRNA-124 as a Major Regulator of Enhanced Endothelial Cell Glycolysis in Pulmonary Arterial Hypertension via PTBP1 (Polypyrimidine Tract Binding Protein) and Pyruvate Kinase M2. Circulation. 2017 Dec 19; 136(25):2451-2467.
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McConnell BV, Koto K, Gutierrez-Hartmann A. Nuclear and cytoplasmic LIMK1 enhances human breast cancer progression. Mol Cancer. 2011 Jun 18; 10:75.
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Suurna MV, Ashworth SL, Hosford M, Sandoval RM, Wean SE, Shah BM, Bamburg JR, Molitoris BA. Cofilin mediates ATP depletion-induced endothelial cell actin alterations. Am J Physiol Renal Physiol. 2006 Jun; 290(6):F1398-407.
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