 Nuclear Receptor Coactivators
"Nuclear Receptor Coactivators" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that enhance gene expression when associated with ligand bound activated NUCLEAR RECEPTORS. The coactivators may act through an enzymatic process that affects the rate of transcription or the structure of chromatin. Alternatively nuclear receptor coactivators can function as adaptor proteins that bring nuclear receptors into close proximity with transcriptional complexes.
| Descriptor ID |
D056918
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| MeSH Number(s) |
D12.644.360.024.314 D12.776.157.057.080 D12.776.476.024.394 D12.776.660.675 D12.776.930.617
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivators".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivators".
This graph shows the total number of publications written about "Nuclear Receptor Coactivators" by people in this website by year, and whether "Nuclear Receptor Coactivators" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivators" by people in Profiles.
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Szwarc MM, Lydon JP, O'Malley BW. Steroid receptor coactivators as therapeutic targets in the female reproductive system. J Steroid Biochem Mol Biol. 2015 Nov; 154:32-8.
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Szwarc MM, Kommagani R, Lessey BA, Lydon JP. The p160/steroid receptor coactivator family: potent arbiters of uterine physiology and dysfunction. Biol Reprod. 2014 Nov; 91(5):122.
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Goodall M, Thorburn A. Identifying specific receptors for cargo-mediated autophagy. Cell Res. 2014 Jul; 24(7):783-4.
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Ananthanarayanan M, Li Y, Surapureddi S, Balasubramaniyan N, Ahn J, Goldstein JA, Suchy FJ. Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is critical for NR activation of bile acid transporter genes and is downregulated in cholestasis. Am J Physiol Gastrointest Liver Physiol. 2011 May; 300(5):G771-81.
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Br?s V, Gomes N, Pickle L, Jones KA. A human splicing factor, SKIP, associates with P-TEFb and enhances transcription elongation by HIV-1 Tat. Genes Dev. 2005 May 15; 19(10):1211-26.
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Zhang C, Dowd DR, Staal A, Gu C, Lian JB, van Wijnen AJ, Stein GS, MacDonald PN. Nuclear coactivator-62 kDa/Ski-interacting protein is a nuclear matrix-associated coactivator that may couple vitamin D receptor-mediated transcription and RNA splicing. J Biol Chem. 2003 Sep 12; 278(37):35325-36.
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