3',5'-Cyclic-AMP Phosphodiesterases
"3',5'-Cyclic-AMP Phosphodiesterases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyze the hydrolysis of CYCLIC AMP to form adenosine 5'-phosphate. The enzymes are widely distributed in animal tissue and control the level of intracellular cyclic AMP. Many specific enzymes classified under this heading demonstrate additional spcificity for 3',5'-cyclic IMP and CYCLIC GMP.
Descriptor ID |
D015105
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MeSH Number(s) |
D08.811.277.352.640.150 D12.644.360.008 D12.776.476.008
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Concept/Terms |
3',5'-Cyclic-AMP Phosphodiesterases- 3',5'-Cyclic-AMP Phosphodiesterases
- 3',5' Cyclic AMP Phosphodiesterases
- Phosphodiesterases, 3',5'-Cyclic-AMP
- 3',5'-Cyclic AMP 5'-Nucleotidohydrolase
- 3',5' Cyclic AMP 5' Nucleotidohydrolase
- 5'-Nucleotidohydrolase, 3',5'-Cyclic AMP
- AMP 5'-Nucleotidohydrolase, 3',5'-Cyclic
- 3',5' Cyclic AMP Phosphodiesterase
- 3',5'-Cyclic AMP Phosphodiesterase
- AMP Phosphodiesterase, 3',5'-Cyclic
- Phosphodiesterase, 3',5'-Cyclic AMP
- 3,5-Cyclic AMP Phosphodiesterase
- 3,5 Cyclic AMP Phosphodiesterase
- AMP Phosphodiesterase, 3,5-Cyclic
- Phosphodiesterase, 3,5-Cyclic AMP
- 3',5'-Cyclic Nucleotide Phosphodiesterase
- 3',5' Cyclic Nucleotide Phosphodiesterase
- Nucleotide Phosphodiesterase, 3',5'-Cyclic
- Phosphodiesterase, 3',5'-Cyclic Nucleotide
- 3',5'-Cyclic-Nucleotide Phosphodiesterase
- Phosphodiesterase, 3',5'-Cyclic-Nucleotide
- 3',5'-Nucleotide Phosphodiesterase
- 3',5' Nucleotide Phosphodiesterase
- Phosphodiesterase, 3',5'-Nucleotide
- CAMP Phosphodiesterase
- Phosphodiesterase, CAMP
- 3,5-Cyclic AMP 5-Nucleotidohydrolase
- 3,5 Cyclic AMP 5 Nucleotidohydrolase
- 5-Nucleotidohydrolase, 3,5-Cyclic AMP
- AMP 5-Nucleotidohydrolase, 3,5-Cyclic
- 3',5'-Cyclic-AMP Phosphodiesterase
- Phosphodiesterase, 3',5'-Cyclic-AMP
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Below are MeSH descriptors whose meaning is more general than "3',5'-Cyclic-AMP Phosphodiesterases".
Below are MeSH descriptors whose meaning is more specific than "3',5'-Cyclic-AMP Phosphodiesterases".
This graph shows the total number of publications written about "3',5'-Cyclic-AMP Phosphodiesterases" by people in this website by year, and whether "3',5'-Cyclic-AMP Phosphodiesterases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1996 | 0 | 1 | 1 | 2000 | 0 | 1 | 1 | 2001 | 0 | 1 | 1 | 2006 | 1 | 0 | 1 | 2008 | 0 | 1 | 1 | 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "3',5'-Cyclic-AMP Phosphodiesterases" by people in Profiles.
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Pratt EPS, Harvey KE, Salyer AE, Hockerman GH. Regulation of cAMP accumulation and activity by distinct phosphodiesterase subtypes in INS-1 cells and human pancreatic ?-cells. PLoS One. 2019; 14(8):e0215188.
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Cole JB, Manyama M, Kimwaga E, Mathayo J, Larson JR, Liberton DK, Lukowiak K, Ferrara TM, Riccardi SL, Li M, Mio W, Prochazkova M, Williams T, Li H, Jones KL, Klein OD, Santorico SA, Hallgrimsson B, Spritz RA. Genomewide Association Study of African Children Identifies Association of SCHIP1 and PDE8A with Facial Size and Shape. PLoS Genet. 2016 08; 12(8):e1006174.
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Knight WE, Yan C. Cardiac cyclic nucleotide phosphodiesterases: function, regulation, and therapeutic prospects. Horm Metab Res. 2012 Sep; 44(10):766-75.
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Movsesian M, Stehlik J, Vandeput F, Bristow MR. Phosphodiesterase inhibition in heart failure. Heart Fail Rev. 2009 Dec; 14(4):255-63.
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Willoughby D, Wong W, Schaack J, Scott JD, Cooper DM. An anchored PKA and PDE4 complex regulates subplasmalemmal cAMP dynamics. EMBO J. 2006 May 17; 25(10):2051-61.
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Kuhlenb?umer G, Berger K, Huge A, Lange E, Kessler C, John U, Funke H, Nabavi DG, St?gbauer F, Ringelstein EB, Stoll M. Evaluation of single nucleotide polymorphisms in the phosphodiesterase 4D gene (PDE4D) and their association with ischaemic stroke in a large German cohort. J Neurol Neurosurg Psychiatry. 2006 Apr; 77(4):521-4.
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Larsen GL, Loader JE, Fratelli C, Brian Kang JK, Dakhama A, Colasurdo GN. Phosphodiesterase IV and neutral endopeptidase in airways from developing and allergen sensitized rabbits. Pulm Pharmacol Ther. 2006; 19(5):335-42.
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Boguniewicz M, Leung DY. Pathophysiologic mechanisms in atopic dermatitis. Semin Cutan Med Surg. 2001 Dec; 20(4):217-25.
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Varkevisser B, Kinnamon SC. Sweet taste transduction in hamster: role of protein kinases. J Neurophysiol. 2000 May; 83(5):2526-32.
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Focaccio A, Peeters G, Movsesian M, Roden R, Eki Y, Krall J, Bristow MR. Mechanism of action of OPC-8490 in human ventricular myocardium. Circulation. 1996 Feb 15; 93(4):817-25.
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