 Adenomatous Polyposis Coli Protein
"Adenomatous Polyposis Coli Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A negative regulator of beta-catenin signaling which is mutant in ADENOMATOUS POLYPOSIS COLI and GARDNER SYNDROME.
| Descriptor ID |
D025601
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| MeSH Number(s) |
D05.500.117.249 D12.776.220.040 D12.776.476.081.249 D12.776.624.776.010
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Adenomatous Polyposis Coli Protein".
Below are MeSH descriptors whose meaning is more specific than "Adenomatous Polyposis Coli Protein".
This graph shows the total number of publications written about "Adenomatous Polyposis Coli Protein" by people in this website by year, and whether "Adenomatous Polyposis Coli Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 | | 2004 | 1 | 1 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 1 | 0 | 1 | | 2015 | 2 | 0 | 2 | | 2016 | 2 | 0 | 2 | | 2018 | 1 | 2 | 3 | | 2019 | 0 | 2 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Adenomatous Polyposis Coli Protein" by people in Profiles.
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Zhong J, Guo Y, Lu S, Song K, Wang Y, Feng L, Zheng Z, Zhang Q, Wei J, Sang P, Shi Y, Cai J, Chen G, Liu CY, Yang X, Zhang J. Rational design of a sensitivity-enhanced tracer for discovering efficient APC-Asef inhibitors. Nat Commun. 2022 08 24; 13(1):4961.
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Karlitz JJ, Phillips A, Sorrells KS, Rao S. Genetic Analysis of Archived Tumor Specimens for Hereditary Colorectal Cancer Syndromes in the Cajuns of Louisiana, a US Founder Population. Clin Transl Gastroenterol. 2021 09 21; 12(9):e00392.
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Lieu CH, Golemis EA, Serebriiskii IG, Newberg J, Hemmerich A, Connelly C, Messersmith WA, Eng C, Eckhardt SG, Frampton G, Cooke M, Meyer JE. Comprehensive Genomic Landscapes in Early and Later Onset Colorectal Cancer. Clin Cancer Res. 2019 10 01; 25(19):5852-5858.
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Romagnolo DF, Donovan MG, Doetschman TC, Selmin OI. n-6 Linoleic Acid Induces Epigenetics Alterations Associated with Colonic Inflammation and Cancer. Nutrients. 2019 Jan 15; 11(1).
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Jones JC, Brindley CD, Elder NH, Myers MG, Rajala MW, Dekaney CM, McNamee EN, Frey MR, Shroyer NF, Dempsey PJ. Cellular Plasticity of Defa4Cre-Expressing Paneth Cells in Response to Notch Activation and Intestinal Injury. Cell Mol Gastroenterol Hepatol. 2019; 7(3):533-554.
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Chan JL, Wu S, Geis AL, Chan GV, Gomes TAM, Beck SE, Wu X, Fan H, Tam AJ, Chung L, Ding H, Wang H, Pardoll DM, Housseau F, Sears CL. Non-toxigenic Bacteroides fragilis (NTBF) administration reduces bacteria-driven chronic colitis and tumor development independent of polysaccharide A. Mucosal Immunol. 2019 01; 12(1):164-177.
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Yang X, Zhong J, Zhang Q, Qian J, Song K, Ruan C, Xu J, Ding K, Zhang J. Rational Design and Structure Validation of a Novel Peptide Inhibitor of the Adenomatous-Polyposis-Coli (APC)-Rho-Guanine-Nucleotide-Exchange-Factor-4 (Asef) Interaction. J Med Chem. 2018 09 13; 61(17):8017-8028.
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Septer S, Bohaty B, Onikul R, Kumar V, Williams KB, Attard TM, Friesen CA, Friesen LR. Dental anomalies in pediatric patients with familial adenomatous polyposis. Fam Cancer. 2018 04; 17(2):229-234.
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Obuch JC, Ahnen DJ. Colorectal Cancer: Genetics is Changing Everything. Gastroenterol Clin North Am. 2016 09; 45(3):459-76.
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Septer S, Lawson CE, Anant S, Attard T. Familial adenomatous polyposis in pediatrics: natural history, emerging surveillance and management protocols, chemopreventive strategies, and areas of ongoing debate. Fam Cancer. 2016 07; 15(3):477-85.
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