 WW Domain-Containing Oxidoreductase
"WW Domain-Containing Oxidoreductase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A short chain oxidoreductase that contains two N-terminal WW DOMAINS and functions as a tumor suppressor and in APOPTOSIS. It is also required for bone development.
| Descriptor ID |
D000074584
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| MeSH Number(s) |
D08.811.682.047.820.900.500 D12.776.624.776.980
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "WW Domain-Containing Oxidoreductase".
Below are MeSH descriptors whose meaning is more specific than "WW Domain-Containing Oxidoreductase".
This graph shows the total number of publications written about "WW Domain-Containing Oxidoreductase" by people in this website by year, and whether "WW Domain-Containing Oxidoreductase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2026 | 1 | 0 | 1 |
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Below are the most recent publications written about "WW Domain-Containing Oxidoreductase" by people in Profiles.
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Bidany-Mizrahi T, Maroun K, Mancini M, Hidmi O, Ansari I, Monin J, Keidar Haran T, Maly A, Melino G, Candi E, Aqeilan RI. WWOX maintains epidermal identity and suppresses EMT to prevent aggressive cutaneous squamous cell carcinoma. Proc Natl Acad Sci U S A. 2026 Apr 21; 123(16):e2534844123.
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Lange EM, Beebe-Dimmer JL, Ray AM, Zuhlke KA, Ellis J, Wang Y, Walters S, Cooney KA. Genome-wide linkage scan for prostate cancer susceptibility from the University of Michigan Prostate Cancer Genetics Project: suggestive evidence for linkage at 16q23. Prostate. 2009 Mar 01; 69(4):385-91.
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Nunez MI, Rosen DG, Ludes-Meyers JH, Abba MC, Kil H, Page R, Klein-Szanto AJ, Godwin AK, Liu J, Mills GB, Aldaz CM. WWOX protein expression varies among ovarian carcinoma histotypes and correlates with less favorable outcome. BMC Cancer. 2005 Jun 27; 5:64.
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Sze CI, Su M, Pugazhenthi S, Jambal P, Hsu LJ, Heath J, Schultz L, Chang NS. Down-regulation of WW domain-containing oxidoreductase induces Tau phosphorylation in vitro. A potential role in Alzheimer's disease. J Biol Chem. 2004 Jul 16; 279(29):30498-506.
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