 Ataxins
"Ataxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of predominantly nuclear proteins that regulate gene transcription and protein degradation. The expansion of CAG trinucleotide repeats in genes that encode Ataxins is associated with SPINOCEREBELLAR ATAXIAS (SCA). In SCA patients, the number of CAG repeats correlates with the severity of disease and inversely correlates with the age of disease onset.
| Descriptor ID |
D000067528
|
| MeSH Number(s) |
D12.776.631.069 D12.776.660.075
|
| Concept/Terms |
Ataxins- Ataxins
- Spinocerebellar Ataxia Proteins
- Ataxia Proteins, Spinocerebellar
- Proteins, Spinocerebellar Ataxia
- Ataxin Proteins
- Proteins, Ataxin
|
Below are MeSH descriptors whose meaning is more general than "Ataxins".
Below are MeSH descriptors whose meaning is more specific than "Ataxins".
This graph shows the total number of publications written about "Ataxins" by people in this website by year, and whether "Ataxins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 | | 2008 | 0 | 1 | 1 | | 2013 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Ataxins" by people in Profiles.
-
Yoon JH, Abdelmohsen K, Kim J, Yang X, Martindale JL, Tominaga-Yamanaka K, White EJ, Orjalo AV, Rinn JL, Kreft SG, Wilson GM, Gorospe M. Scaffold function of long non-coding RNA HOTAIR in protein ubiquitination. Nat Commun. 2013; 4:2939.
-
Matsumoto T, Kubo S, Meszaros LB, Corsi KA, Cooper GM, Li G, Usas A, Osawa A, Fu FH, Huard J. The influence of sex on the chondrogenic potential of muscle-derived stem cells: implications for cartilage regeneration and repair. Arthritis Rheum. 2008 Dec; 58(12):3809-19.
-
Barclay WW, Axanova LS, Chen W, Romero L, Maund SL, Soker S, Lees CJ, Cramer SD. Characterization of adult prostatic progenitor/stem cells exhibiting self-renewal and multilineage differentiation. Stem Cells. 2008 Mar; 26(3):600-10.
|
People  People who have written about this concept. _
Similar Concepts
People who have written about this concept.
_
Top Journals
Top journals in which articles about this concept have been published.
|