Intracellular signaling proteins that are defined by the presence of a NUCLEOTIDE-binding region and LEUCINE-rich repeats. Their general structure consists of any of a variety of effector domains at their N-termini such as a caspase recruitment domain (CARD), a central nucleotide-binding domain, and a variable number of C-terminal leucine-rich repeats. They are important for pathogen recognition in the INNATE IMMUNE RESPONSE of animals and plants. Members of the NLR protein family include the NOD SIGNALING ADAPTOR PROTEINS.

Descriptor ID	D000070576
MeSH Number(s)	D12.644.360.539
Concept/Terms	NLR Proteins NLR Proteins Proteins, NLR NLR Protein Protein, NLR NOD-like Receptors NOD like Receptors Receptors, NOD-like Nucleotide-binding Domain Leucine-rich Repeat Proteins Nucleotide binding Domain Leucine rich Repeat Proteins

Below are MeSH descriptors whose meaning is more general than "NLR Proteins".

Below are MeSH descriptors whose meaning is related to "NLR Proteins".

Below are MeSH descriptors whose meaning is more specific than "NLR Proteins".