 Proto-Oncogene Proteins c-myb
"Proto-Oncogene Proteins c-myb" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cellular DNA-binding proteins encoded by the myb gene (GENES, MYB). They are expressed in a wide variety of cells including thymocytes and lymphocytes, and regulate cell differentiation. Overexpression of myb is associated with autoimmune diseases and malignancies.
| Descriptor ID |
D020598
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| MeSH Number(s) |
D12.776.260.675 D12.776.624.664.700.188 D12.776.930.725
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| Concept/Terms |
Proto-Oncogene Proteins c-myb- Proto-Oncogene Proteins c-myb
- Proto Oncogene Proteins c myb
- c-myb, Proto-Oncogene Proteins
- Proto-Oncogene Protein myb
- Proto Oncogene Protein myb
- myb, Proto-Oncogene Protein
- myb Proto-Oncogene Proteins
- Proto-Oncogene Proteins, myb
- myb Proto Oncogene Proteins
- Proto-Oncogene Products c-myb
- Proto Oncogene Products c myb
- c-myb, Proto-Oncogene Products
- Proto-Oncogene Proteins myb
- Proto Oncogene Proteins myb
- myb, Proto-Oncogene Proteins
- c-myb Protein
- c myb Protein
- c-myb Proteins
- c myb Proteins
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-myb".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-myb".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-myb" by people in this website by year, and whether "Proto-Oncogene Proteins c-myb" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 1995 | 0 | 1 | 1 | | 1996 | 0 | 1 | 1 | | 1997 | 0 | 2 | 2 | | 1999 | 0 | 1 | 1 | | 2013 | 1 | 0 | 1 | | 2018 | 2 | 0 | 2 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-myb" by people in Profiles.
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Porazzi P, De Dominici M, Salvino J, Calabretta B. Targeting the CDK6 Dependence of Ph+ Acute Lymphoblastic Leukemia. Genes (Basel). 2021 08 29; 12(9).
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D'Aguanno S, Valentini E, Tupone MG, Desideri M, Di Martile M, Spagnuolo M, Buglioni S, Ercolani C, Falcone I, De Dominici M, Milella M, Rizzo MG, Calabretta B, Cota C, Anichini A, Trisciuoglio D, Del Bufalo D. Semaphorin 5A drives melanoma progression: role of Bcl-2, miR-204 and c-Myb. J Exp Clin Cancer Res. 2018 Nov 19; 37(1):278.
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Spagnuolo M, Regazzo G, De Dominici M, Sacconi A, Pelosi A, Korita E, Marchesi F, Pisani F, Magenta A, Lulli V, Cordone I, Mengarelli A, Strano S, Blandino G, Rizzo MG, Calabretta B. Transcriptional activation of the miR-17-92 cluster is involved in the growth-promoting effects of MYB in human Ph-positive leukemia cells. Haematologica. 2019 01; 104(1):82-92.
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Tan FE, Vladar EK, Ma L, Fuentealba LC, Hoh R, Espinoza FH, Axelrod JD, Alvarez-Buylla A, Stearns T, Kintner C, Krasnow MA. Myb promotes centriole amplification and later steps of the multiciliogenesis program. Development. 2013 Oct; 140(20):4277-86.
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Vasilevsky NA, Ruby CE, Hurlin PJ, Weinberg AD. OX40 engagement stabilizes Mxd4 and Mnt protein levels in antigen-stimulated T cells leading to an increase in cell survival. Eur J Immunol. 2011 Apr; 41(4):1024-34.
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Goode EL, Chenevix-Trench G, Song H, Ramus SJ, Notaridou M, Lawrenson K, Widschwendter M, Vierkant RA, Larson MC, Kjaer SK, Birrer MJ, Berchuck A, Schildkraut J, Tomlinson I, Kiemeney LA, Cook LS, Gronwald J, Garcia-Closas M, Gore ME, Campbell I, Whittemore AS, Sutphen R, Phelan C, Anton-Culver H, Pearce CL, Lambrechts D, Rossing MA, Chang-Claude J, Moysich KB, Goodman MT, D?rk T, Nevanlinna H, Ness RB, Rafnar T, Hogdall C, Hogdall E, Fridley BL, Cunningham JM, Sieh W, McGuire V, Godwin AK, Cramer DW, Hernandez D, Levine D, Lu K, Iversen ES, Palmieri RT, Houlston R, van Altena AM, Aben KK, Massuger LF, Brooks-Wilson A, Kelemen LE, Le ND, Jakubowska A, Lubinski J, Medrek K, Stafford A, Easton DF, Tyrer J, Bolton KL, Harrington P, Eccles D, Chen A, Molina AN, Davila BN, Arango H, Tsai YY, Chen Z, Risch HA, McLaughlin J, Narod SA, Ziogas A, Brewster W, Gentry-Maharaj A, Menon U, Wu AH, Stram DO, Pike MC, Beesley J, Webb PM, Chen X, Ekici AB, Thiel FC, Beckmann MW, Yang H, Wentzensen N, Lissowska J, Fasching PA, Despierre E, Amant F, Vergote I, Doherty J, Hein R, Wang-Gohrke S, Lurie G, Carney ME, Thompson PJ, Runnebaum I, Hillemanns P, D?rst M, Antonenkova N, Bogdanova N, Leminen A, Butzow R, Heikkinen T, Stefansson K, Sulem P, Besenbacher S, Sellers TA, Gayther SA, Pharoah PD. A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat Genet. 2010 Oct; 42(10):874-9.
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Ess KC, Witte DP, Bascomb CP, Aronow BJ. Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. Oncogene. 1999 Jan 28; 18(4):1103-11.
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Brandt TL, Fraser DJ, Leal S, Halandras PM, Kroll AR, Kroll DJ. c-Myb trans-activates the human DNA topoisomerase IIalpha gene promoter. J Biol Chem. 1997 Mar 07; 272(10):6278-84.
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Cooper JP, Nimmo ER, Allshire RC, Cech TR. Regulation of telomere length and function by a Myb-domain protein in fission yeast. Nature. 1997 Feb 20; 385(6618):744-7.
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Hutton JJ, Ess KC, Witte DP, Aronow BJ. Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes. Trans Am Clin Climatol Assoc. 1996; 107:115-24.
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