 Stathmin
"Stathmin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous phosphoprotein that serves as an intracellular substrate for a variety of SIGNAL TRANSDUCTION PATHWAYS. PHOSPHORYLATION of stathmin occurs during CELL CYCLE progression, and stathmin functions as a microtubule-destabilizing protein that promotes MICROTUBULE depolymerization during INTERPHASE and late MITOSIS. Stathmin is expressed at very high levels in a variety of human CANCERS.
| Descriptor ID |
D050777
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| MeSH Number(s) |
D12.776.220.600.450.480 D12.776.624.664.700.957 D12.776.744.772
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| Concept/Terms |
Stathmin- Stathmin
- Leukemia-Associated Phosphoprotein p18
- Leukemia Associated Phosphoprotein p18
- p18, Leukemia-Associated Phosphoprotein
- Metablastin
- Prosolin
- Op18 Phosphoprotein
- Phosphoprotein, Op18
- Phosphoprotein p18
- p18, Phosphoprotein
- Phosphoprotein p19
- p19, Phosphoprotein
- Lap18 Protein
- Oncoprotein 18
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Below are MeSH descriptors whose meaning is more general than "Stathmin".
Below are MeSH descriptors whose meaning is more specific than "Stathmin".
This graph shows the total number of publications written about "Stathmin" by people in this website by year, and whether "Stathmin" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2013 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Stathmin" by people in Profiles.
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Reyes HD, Miecznikowski J, Gonzalez-Bosquet J, Devor EJ, Zhang Y, Thiel KW, Samuelson MI, McDonald M, Stephan JM, Hanjani P, Guntupalli S, Tewari KS, Backes F, Ramirez N, Fleming GF, Filiaci V, Birrer MJ, Leslie KK. High stathmin expression is a marker for poor clinical outcome in endometrial cancer: An NRG oncology group/gynecologic oncology group study. Gynecol Oncol. 2017 08; 146(2):247-253.
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Li J, Hu G, Kong F, Wu K, Song K, He J, Sun W. Elevated STMN1 Expression Correlates with Poor Prognosis in Patients with Pancreatic Ductal Adenocarcinoma. Pathol Oncol Res. 2015 Sep; 21(4):1013-20.
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Li J, Kong F, Wu K, Song K, He J, Sun W. miR-193b directly targets STMN1 and uPA genes and suppresses tumor growth and metastasis in pancreatic cancer. Mol Med Rep. 2014 Nov; 10(5):2613-20.
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Hindle AG, Martin SL. Cytoskeletal regulation dominates temperature-sensitive proteomic changes of hibernation in forebrain of 13-lined ground squirrels. PLoS One. 2013; 8(8):e71627.
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