 Telomere-Binding Proteins
"Telomere-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Proteins that specifically bind to TELOMERES. Proteins in this class include those that perform functions such as telomere capping, telomere maintenance and telomere stabilization.
| Descriptor ID |
D034501
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| MeSH Number(s) |
D12.776.260.735 D12.776.660.235.700
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| Concept/Terms |
Telomer-Binding Protein, alpha-Subunit- Telomer-Binding Protein, alpha-Subunit
- Telomer Binding Protein, alpha Subunit
- alpha-Subunit Telomer-Binding Protein
- alpha-Telomere-Binding Protein
- alpha Telomere Binding Protein
Telomer-Binding Protein, beta-Subunit- Telomer-Binding Protein, beta-Subunit
- Telomer Binding Protein, beta Subunit
- beta-Subunit Telomer-Binding Protein
- beta-Telomere-Binding Protein
- beta Telomere Binding Protein
Double-Stranded Telomere-Binding Proteins- Double-Stranded Telomere-Binding Proteins
- Double Stranded Telomere Binding Proteins
- Telomere-Binding Proteins, Double-Stranded
- Telomere-Binding Proteins, Double Stranded
- Telomere Binding Proteins, Double Stranded
- Double-Stranded Telomeric Binding Protein
- Double Stranded Telomeric Binding Protein
Single-Stranded Telomere-Binding Proteins- Single-Stranded Telomere-Binding Proteins
- Single Stranded Telomere Binding Proteins
- Telomere-Binding Proteins, Single-Stranded
- Telomere Binding Proteins, Single Stranded
- Single-Stranded Telomere-Binding Protein
- Single Stranded Telomere Binding Protein
- Telomere-Binding Protein, Single-Stranded
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Below are MeSH descriptors whose meaning is more general than "Telomere-Binding Proteins".
Below are MeSH descriptors whose meaning is more specific than "Telomere-Binding Proteins".
This graph shows the total number of publications written about "Telomere-Binding Proteins" by people in this website by year, and whether "Telomere-Binding Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 0 | 1 | | 1997 | 2 | 0 | 2 | | 1998 | 1 | 0 | 1 | | 2001 | 1 | 0 | 1 | | 2002 | 5 | 0 | 5 | | 2003 | 4 | 1 | 5 | | 2004 | 3 | 0 | 3 | | 2005 | 3 | 0 | 3 | | 2006 | 1 | 0 | 1 | | 2007 | 1 | 0 | 1 | | 2008 | 3 | 0 | 3 | | 2009 | 4 | 0 | 4 | | 2010 | 1 | 2 | 3 | | 2011 | 4 | 0 | 4 | | 2012 | 4 | 0 | 4 | | 2013 | 1 | 4 | 5 | | 2014 | 2 | 0 | 2 | | 2015 | 3 | 0 | 3 | | 2016 | 1 | 2 | 3 | | 2017 | 2 | 0 | 2 | | 2018 | 3 | 0 | 3 | | 2019 | 0 | 1 | 1 | | 2020 | 2 | 1 | 3 | | 2021 | 2 | 0 | 2 | | 2022 | 0 | 1 | 1 | | 2023 | 1 | 2 | 3 | | 2024 | 4 | 0 | 4 | | 2025 | 0 | 1 | 1 |
To return to the timeline, click here.
Below are the most recent publications written about "Telomere-Binding Proteins" by people in Profiles.
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Moeller-McCoy CA, Wieser TA, Lubin JW, Gillespie AE, Ramirez JA, Paschini M, Wuttke DS, Lundblad V. The canonical RPA complex interacts with Est3 to regulate yeast telomerase activity. Proc Natl Acad Sci U S A. 2025 Feb 18; 122(7):e2419309122.
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Nageshan RK, Krogan N, Cooper JP. Parallel genetic screens identify nuclear envelope homeostasis as a key determinant of telomere entanglement resolution in fission yeast. G3 (Bethesda). 2024 Jul 08; 14(7).
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Cai SW, Takai H, Zaug AJ, Dilgen TC, Cech TR, Walz T, de Lange T. POT1 recruits and regulates CST-Pola/primase at human telomeres. Cell. 2024 Jul 11; 187(14):3638-3651.e18.
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Nageshan RK, Ortega R, Krogan N, Cooper JP. Fate of telomere entanglements is dictated by the timing of anaphase midregion nuclear envelope breakdown. Nat Commun. 2024 Jun 03; 15(1):4707.
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Olson CL, Wuttke DS. Guardians of the Genome: How the Single-Stranded DNA-Binding Proteins RPA and CST Facilitate Telomere Replication. Biomolecules. 2024 Feb 22; 14(3).
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Hoerr RE, Eng A, Payen C, Di Rienzi SC, Raghuraman MK, Dunham MJ, Brewer BJ, Friedman KL. Hotspot of de novo telomere addition stabilizes linear amplicons in yeast grown in sulfate-limiting conditions. Genetics. 2023 05 26; 224(2).
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Ngo K, Gittens TH, Gonzalez DI, Hatmaker EA, Plotkin S, Engle M, Friedman GA, Goldin M, Hoerr RE, Eichman BF, Rokas A, Benton ML, Friedman KL. A comprehensive map of hotspots of de novo telomere addition in Saccharomyces cerevisiae. Genetics. 2023 05 26; 224(2).
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Barbour AT, Wuttke DS. RPA-like single-stranded DNA-binding protein complexes including CST serve as specialized processivity factors for polymerases. Curr Opin Struct Biol. 2023 08; 81:102611.
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Olson CL, Barbour AT, Wuttke DS. Filling in the blanks: how the C-strand catches up to the G-strand at replicating telomeres using CST. Nat Struct Mol Biol. 2022 08; 29(8):730-733.
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Zaug AJ, Lim CJ, Olson CL, Carilli MT, Goodrich KJ, Wuttke DS, Cech TR. CST does not evict elongating telomerase but prevents initiation by ssDNA binding. Nucleic Acids Res. 2021 11 18; 49(20):11653-11665.
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