 Bcl-2-Like Protein 11
"Bcl-2-Like Protein 11" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A BCL-2-like protein that has a C-terminal BCL-2 homology (BH3) domain and forms heterodimers with other BCL-2 FAMILY PROTEINS. It is a strong inducer of APOPTOSIS and ANOIKIS; several isoforms are expressed (BimEL, Bim L, Bim-alpha, Bim-s; and Bim-gamma) that have different potencies for inducing apoptosis.
| Descriptor ID |
D000072224
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| MeSH Number(s) |
D12.644.360.075.323 D12.776.476.075.323 D12.776.543.116 D12.776.624.664.700.025
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| Concept/Terms |
Bcl-2-Like Protein 11- Bcl-2-Like Protein 11
- 11, Bcl-2-Like Protein
- Bcl 2 Like Protein 11
- Protein 11, Bcl-2-Like
- Bcl-2-Interacting Mediator of Cell Death
- Bcl 2 Interacting Mediator of Cell Death
- Bcl-2-Binding Protein, BIM
- BIM Bcl-2-Binding Protein
- Bcl 2 Binding Protein, BIM
- Protein, BIM Bcl-2-Binding
- BCL2L11 Protein
- Protein, BCL2L11
- BIM Protein
- Protein, BIM
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Below are MeSH descriptors whose meaning is more general than "Bcl-2-Like Protein 11".
Below are MeSH descriptors whose meaning is more specific than "Bcl-2-Like Protein 11".
This graph shows the total number of publications written about "Bcl-2-Like Protein 11" by people in this website by year, and whether "Bcl-2-Like Protein 11" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
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| 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 1 | 1 | | 2005 | 0 | 2 | 2 | | 2006 | 0 | 2 | 2 | | 2007 | 0 | 2 | 2 | | 2008 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 0 | 2 | 2 | | 2011 | 0 | 1 | 1 | | 2014 | 0 | 1 | 1 | | 2015 | 0 | 1 | 1 | | 2016 | 2 | 1 | 3 | | 2017 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Bcl-2-Like Protein 11" by people in Profiles.
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Slansky JE, Spellman PT. Alternative Splicing in Tumors - A Path to Immunogenicity? N Engl J Med. 2019 02 28; 380(9):877-880.
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Mukherjee N, Lu Y, Almeida A, Lambert K, Shiau CW, Su JC, Luo Y, Fujita M, Robinson WA, Robinson SE, Norris DA, Shellman YG. Use of a MCL-1 inhibitor alone to de-bulk melanoma and in combination to kill melanoma initiating cells. Oncotarget. 2017 Jul 18; 8(29):46801-46817.
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Kurayoshi K, Okuno J, Ozono E, Iwanaga R, Bradford AP, Kugawa K, Araki K, Ohtani K. The phosphatidyl inositol 3 kinase pathway does not suppress activation of the ARF and BIM genes by deregulated E2F1 activity. Biochem Biophys Res Commun. 2017 Jan 22; 482(4):784-790.
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Annis RP, Swahari V, Nakamura A, Xie AX, Hammond SM, Deshmukh M. Mature neurons dynamically restrict apoptosis via redundant premitochondrial brakes. FEBS J. 2016 12; 283(24):4569-4582.
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Kotzin JJ, Spencer SP, McCright SJ, Kumar DBU, Collet MA, Mowel WK, Elliott EN, Uyar A, Makiya MA, Dunagin MC, Harman CCD, Virtue AT, Zhu S, Bailis W, Stein J, Hughes C, Raj A, Wherry EJ, Goff LA, Klion AD, Rinn JL, Williams A, Flavell RA, Henao-Mejia J. The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan. Nature. 2016 09 08; 537(7619):239-243.
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Kitamura H, Ozono E, Iwanaga R, Bradford AP, Okuno J, Shimizu E, Kurayoshi K, Kugawa K, Toh H, Ohtani K. Identification of novel target genes specifically activated by deregulated E2F in human normal fibroblasts. Genes Cells. 2015 Sep; 20(9):739-57.
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DuBray BJ, Conzen KD, Upadhya GA, Gunter KL, Jia J, Knolhoff BL, Mohanakumar T, Chapman WC, Anderson CD. BH3-only proteins contribute to steatotic liver ischemia-reperfusion injury. J Surg Res. 2015 Apr; 194(2):653-658.
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Estrada-Bernal A, Palanichamy K, Ray Chaudhury A, Van Brocklyn JR. Induction of brain tumor stem cell apoptosis by FTY720: a potential therapeutic agent for glioblastoma. Neuro Oncol. 2012 Apr; 14(4):405-15.
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Tang Y, Orth JD, Xie T, Mitchison TJ. Rapid induction of apoptosis during Kinesin-5 inhibitor-induced mitotic arrest in HL60 cells. Cancer Lett. 2011 Nov 01; 310(1):15-24.
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Barron L, Dooms H, Hoyer KK, Kuswanto W, Hofmann J, O'Gorman WE, Abbas AK. Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells. J Immunol. 2010 Dec 01; 185(11):6426-30.
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