 Proto-Oncogene Proteins c-bcl-6
"Proto-Oncogene Proteins c-bcl-6" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A DNA-binding protein that contains an N-terminal BTB (POZ) DOMAIN and C-terminal CYS2-HIS2 ZINC FINGERS. It represses GENETIC TRANSCRIPTION of target genes by recruiting HISTONE DEACETYLASES. Aberrant Blc-6 expression is associated with certain types of human B-CELL LYMPHOMA.
| Descriptor ID |
D051560
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| MeSH Number(s) |
D12.776.260.660 D12.776.624.664.700.170 D12.776.930.715
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| Concept/Terms |
Proto-Oncogene Proteins c-bcl-6- Proto-Oncogene Proteins c-bcl-6
- Proto Oncogene Proteins c bcl 6
- c-bcl-6, Proto-Oncogene Proteins
- B-Cell Lymphoma 6 Protein
- B Cell Lymphoma 6 Protein
- Zinc Finger Protein 51
- c-bcl-6 Protein
- c bcl 6 Protein
- bcl-6 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, bcl-6
- bcl 6 Proto Oncogene Proteins
- c-bcl-6 Proto-Oncogene Proteins
- Proto-Oncogene Proteins, c-bcl-6
- c bcl 6 Proto Oncogene Proteins
- Proto-Oncogene Protein bcl-6
- Proto Oncogene Protein bcl 6
- bcl-6, Proto-Oncogene Protein
- Proto-Oncogene Protein c-bcl-6
- Proto Oncogene Protein c bcl 6
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Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-bcl-6".
Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-bcl-6".
This graph shows the total number of publications written about "Proto-Oncogene Proteins c-bcl-6" by people in this website by year, and whether "Proto-Oncogene Proteins c-bcl-6" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2011 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2019 | 1 | 0 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Proto-Oncogene Proteins c-bcl-6" by people in Profiles.
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Klarquist J, Cantrell R, Lehn MA, Lampe K, Hennies CM, Hoebe K, Janssen EM. Type I IFN Drives Experimental Systemic Lupus Erythematosus by Distinct Mechanisms in CD4 T Cells and B Cells. Immunohorizons. 2020 03 11; 4(3):140-152.
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Hurtz C, Chan LN, Geng H, Ballabio E, Xiao G, Deb G, Khoury H, Chen CW, Armstrong SA, Chen J, Ernst P, Melnick A, Milne T, M?schen M. Rationale for targeting BCL6 in MLL-rearranged acute lymphoblastic leukemia. Genes Dev. 2019 09 01; 33(17-18):1265-1279.
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Behdad A, Boddy CS, Fought AJ, Taxter T, Falkiewicz MK, Ayers E, Chen QC, Chen YH, Karmali R, Pro B, Winter JN, Landsburg DJ, Gordon LI, Kaplan JB. Survival outcomes of diffuse large B-cell lymphoma by association with concurrent or antecedent follicular lymphoma and double hit status. Leuk Lymphoma. 2019 12; 60(13):3266-3271.
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Santiago T, Clay MR, Allen SJ, Orr BA. Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma. Mod Pathol. 2017 06; 30(6):884-891.
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Basso K, Schneider C, Shen Q, Holmes AB, Setty M, Leslie C, Dalla-Favera R. BCL6 positively regulates AID and germinal center gene expression via repression of miR-155. J Exp Med. 2012 Dec 17; 209(13):2455-65.
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Chen Z, Viboolsittiseri SS, O'Connor BP, Wang JH. Target DNA sequence directly regulates the frequency of activation-induced deaminase-dependent mutations. J Immunol. 2012 Oct 15; 189(8):3970-82.
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Dougherty MJ, Wilmoth DM, Tooke LS, Shaikh TH, Gai X, Hakonarson H, Biegel JA. Implementation of high resolution single nucleotide polymorphism array analysis as a clinical test for patients with hematologic malignancies. Cancer Genet. 2011 Jan; 204(1):26-38.
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Porter CC, Liang X, Gralla J, McGavran L, Albano EA. BCL6 expression correlates with monomorphic histology in children with posttransplantation lymphoproliferative disease. J Pediatr Hematol Oncol. 2008 Sep; 30(9):684-8.
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Logarajah S, Hunter P, Kraman M, Steele D, Lakhani S, Bobrow L, Venkitaraman A, Wagner S. BCL-6 is expressed in breast cancer and prevents mammary epithelial differentiation. Oncogene. 2003 Aug 28; 22(36):5572-8.
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