Elongin
"Elongin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A heterotrimeric protein complex composed of 110 kDa elongin A, 18 kDa elongin B, and 15 kDa elongin C subunits. It functions as a positive regulator of RNA POLYMERASE II, increasing its rate of transcriptional elongation by suppressing transient pausing along the DNA template. Elongin A is the transcriptionally active component; elongins B and C enhance its activity.
| Descriptor ID |
D000075065
|
| MeSH Number(s) |
D12.776.260.197 D12.776.930.215
|
| Concept/Terms |
Elongin- Elongin
- SIII Elongation Factor
- Elongation Factor, SIII
- TF-SIII
- Transcription Factor SIII
- SIII, Transcription Factor
- Elongin Complex
- Complex, Elongin
|
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