 DNA (Cytosine-5-)-Methyltransferases
"DNA (Cytosine-5-)-Methyltransferases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzymes that catalyzes the transfer of a methyl group from S-ADENOSYLMETHIONINE to the 5-position of CYTOSINE residues in DNA.
| Descriptor ID |
D004248
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| MeSH Number(s) |
D08.811.913.555.500.350.100.500
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| Concept/Terms |
DNA (Cytosine-5-)-Methyltransferases- DNA (Cytosine-5-)-Methyltransferases
- DNA (Cytosine-5-)-Methyltransferase
- DNA Cytosine-5-Methylase
- Cytosine-5-Methylase, DNA
- DNA Cytosine 5 Methylase
- DNA (Cytosine 5) Methyltransferase
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Below are MeSH descriptors whose meaning is more general than "DNA (Cytosine-5-)-Methyltransferases".
Below are MeSH descriptors whose meaning is more specific than "DNA (Cytosine-5-)-Methyltransferases".
This graph shows the total number of publications written about "DNA (Cytosine-5-)-Methyltransferases" by people in this website by year, and whether "DNA (Cytosine-5-)-Methyltransferases" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2009 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2015 | 1 | 1 | 2 | | 2016 | 0 | 1 | 1 | | 2017 | 1 | 0 | 1 | | 2018 | 2 | 1 | 3 | | 2019 | 1 | 1 | 2 | | 2020 | 0 | 1 | 1 | | 2021 | 0 | 1 | 1 | | 2022 | 1 | 1 | 2 | | 2025 | 3 | 1 | 4 | | 2026 | 2 | 0 | 2 |
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Below are the most recent publications written about "DNA (Cytosine-5-)-Methyltransferases" by people in Profiles.
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Sarni D, Neary G, Carroll PL, Vink CS, Billard CV, Isobe T, Weng X, Portman JR, McCartney DL, Heyn P, van 't Hof RJ, Morrison LR, Martin CA, Stok C, Harley ME, Leitch A, van den Ancker M, Robertson N, Kitto L, Clark R, Rennie M, Popravko A, McClure JJ, Parry DA, Camiolo G, Leah T, Jakobczyk H, Megaw R, McKie L, Marshall GF, Balkic N, Amiel J, Barragán Arévalo T, Bronken McCarthy G, Buchanan CA, Buffet A, Cascón A, Cogne B, Conrad S, Cueto-González AM, Currás-Freixes M, Houge GD, Fong CT, George-Abraham JK, Gibson K, Ibáñez L, Longo N, Lussey-Lepoutre C, Miller BS, Moles-Fernandez A, Pillai NR, Tvrdik T, Vincent M, Yokoyama E, Abbott CM, Sanchez-Luque FJ, Ottersbach K, De Bari C, Roelofs AJ, Tillotson R, Kranc KR, Brown SJ, Marioni RE, Crisan M, Göttgens B, Henderson NC, Semple RK, Myant KB, Dzierzak E, Reijns MAM, Sproul D, Jackson AP. A progeria syndrome links DNA hypermethylation to age-related pathology. Nat Genet. 2026 Jul; 58(7):1632-1642.
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Perkins B, Novis CL, Baessler A, Sircy LM, Thomas MM, Harrison-Chau M, Richens AW, Fuchs B, Nguyen NX, Flint K, Winter BS, Varley KE, Hale JS. Dnmt3a-dependent de novo DNA methylation enforces lineage commitment and preserves functionality of memory Th1 and Tfh cells. Cell Rep. 2026 Mar 24; 45(3):117062.
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Becker AL, Borges SG, Pinheiro LGR, Nascimento Freitas D, Duarte L, Nunes E, Cassão G, Poppe J, da Silva RP, Castro MS, Fernandes KA, Andrade CF, de Oliveira Espinel J, de Rezende Rodovalho V, Vinolo MAR, Stein RT, de Souza APD. Analysis of DNA methyltransferase 3 alpha expression during respiratory syncytial virus strain A infection. Sci Rep. 2025 Dec 31; 16(1):3996.
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Yu Z, Vromman A, Nguyen NQH, Schuermans A, Li L, Rentz T, Nakao T, Vellarikkal SK, Uddin MM, Niroula A, Griffin G, Honigberg MC, Lin AE, Gibson CJ, Katz DH, Tahir UA, Fang S, Dron JS, Pan M, Haidermota S, Ganesh S, Antoine T, Weinstock J, Austin TR, Vasan RS, Peloso GM, Hornsby W, Ganz P, Manson JE, Haring B, Kooperberg C, Reiner AP, Bis JC, Psaty BM, Min YI, Correa A, Lange LA, Post WS, Rotter JI, Rich SS, Wilson JG, Ebert BL, Yu B, Ballantyne CM, Coresh J, Sankaran VG, Bick AG, Jaiswal S, Gerszten RE, Libby P, Gupta RM, Natarajan P. Human plasma proteomic profile of clonal hematopoiesis. Nat Commun. 2025 Nov 27; 16(1):11688.
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Hosseini M, Voisin V, Chegini A, Varesi A, Cathelin S, Ayyathan DM, Liu ACH, Yang Y, Wang V, Maher A, Grignano E, Reisz JA, D'Alessandro A, Young K, Wu Y, Fiumara M, Ferrari S, Naldini L, Gaiti F, Pai S, Egan G, Schimmer AD, Bader GD, Dick JE, Xie SZ, Trowbridge JJ, Chan SM. Metformin reduces the competitive advantage of Dnmt3aR878H HSPCs. Nature. 2025 06; 642(8067):421-430.
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Young KA, Hosseini M, Mistry JJ, Morganti C, Mills TS, Cai X, James BT, Nye GJ, Fournier NR, Voisin V, Chegini A, Schimmer AD, Bader GD, Egan G, Mansour MR, Challen GA, Pietras EM, Fisher-Wellman KH, Ito K, Chan SM, Trowbridge JJ. Elevated mitochondrial membrane potential is a therapeutic vulnerability in Dnmt3a-mutant clonal hematopoiesis. Nat Commun. 2025 Apr 16; 16(1):3306.
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Jansson-Fritzberg LI, Sousa CI, Smallegan MJ, Song JJ, Gooding AR, Kasinath V, Rinn JL, Cech TR. DNMT1 inhibition by pUG-fold quadruplex RNA. RNA. 2023 03; 29(3):346-360.
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De Dominici M, DeGregori J. Dnmt3a-Mutant Hematopoietic Stem Cell Rewire IFN? Signaling to Gain Clonal Advantage. Blood Cancer Discov. 2022 05 05; 3(3):178-180.
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Gupta A, Sasse SK, Gruca MA, Sanford L, Dowell RD, Gerber AN. Deconvolution of multiplexed transcriptional responses to wood smoke particles defines rapid aryl hydrocarbon receptor signaling dynamics. J Biol Chem. 2021 10; 297(4):101147.
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Buck JM, O'Neill HC, Stitzel JA. Developmental nicotine exposure engenders intergenerational downregulation and aberrant posttranslational modification of cardinal epigenetic factors in the frontal cortices, striata, and hippocampi of adolescent mice. Epigenetics Chromatin. 2020 03 05; 13(1):13.
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