 Smad Proteins
"Smad Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of proteins that are involved in the translocation of signals from TGF-BETA RECEPTORS; BONE MORPHOGENETIC PROTEIN RECEPTORS; and other surface receptors to the CELL NUCLEUS. They were originally identified as a class of proteins that are related to the mothers against decapentaplegic protein, Drosophila and sma proteins from CAENORHABDITIS ELEGANS.
| Descriptor ID |
D051785
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| MeSH Number(s) |
D12.644.360.024.334 D12.776.157.057.170 D12.776.260.713 D12.776.476.024.428 D12.776.930.806
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| Concept/Terms |
Smad Proteins- Smad Proteins
- Mothers Against Decapentaplegic Homolog
- Sma- and Mad-Related Proteins
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Below are MeSH descriptors whose meaning is more general than "Smad Proteins".
Below are MeSH descriptors whose meaning is more specific than "Smad Proteins".
This graph shows the total number of publications written about "Smad Proteins" by people in this website by year, and whether "Smad Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 | | 2003 | 0 | 2 | 2 | | 2004 | 0 | 2 | 2 | | 2005 | 0 | 1 | 1 | | 2006 | 1 | 0 | 1 | | 2007 | 0 | 1 | 1 | | 2008 | 2 | 1 | 3 | | 2009 | 0 | 1 | 1 | | 2010 | 2 | 1 | 3 | | 2011 | 0 | 2 | 2 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 0 | 3 | 3 | | 2015 | 0 | 1 | 1 | | 2016 | 1 | 2 | 3 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Smad Proteins" by people in Profiles.
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Aisenbrey EA, Bilousova G, Payne K, Bryant SJ. Dynamic mechanical loading and growth factors influence chondrogenesis of induced pluripotent mesenchymal progenitor cells in a cartilage-mimetic hydrogel. Biomater Sci. 2019 Nov 19; 7(12):5388-5403.
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Vincentz JW, Casasnovas JJ, Barnes RM, Que J, Clouthier DE, Wang J, Firulli AB. Exclusion of Dlx5/6 expression from the distal-most mandibular arches enables BMP-mediated specification of the distal cap. Proc Natl Acad Sci U S A. 2016 07 05; 113(27):7563-8.
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Lynn TM, Molloy EL, Masterson JC, Glynn SF, Costello RW, Avdalovic MV, Schelegle ES, Miller LA, Hyde DM, O'Dea S. SMAD Signaling in the Airways of Healthy Rhesus Macaques versus Rhesus Macaques with Asthma Highlights a Relationship Between Inflammation and Bone Morphogenetic Proteins. Am J Respir Cell Mol Biol. 2016 Apr; 54(4):562-73.
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Wahdan-Alaswad R, Harrell JC, Fan Z, Edgerton SM, Liu B, Thor AD. Metformin attenuates transforming growth factor beta (TGF-?) mediated oncogenesis in mesenchymal stem-like/claudin-low triple negative breast cancer. Cell Cycle. 2016; 15(8):1046-59.
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Sanders YY, Cui Z, Le Saux CJ, Horowitz JC, Rangarajan S, Kurundkar A, Antony VB, Thannickal VJ. SMAD-independent down-regulation of caveolin-1 by TGF-?: effects on proliferation and survival of myofibroblasts. PLoS One. 2015; 10(2):e0116995.
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Sheu TJ, Zhou W, Fan J, Zhou H, Zuscik MJ, Xie C, Yin G, Berk BC. Decreased BMP2 signal in GIT1 knockout mice slows bone healing. Mol Cell Biochem. 2014 Dec; 397(1-2):67-74.
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Buczkowicz P, Hoeman C, Rakopoulos P, Pajovic S, Letourneau L, Dzamba M, Morrison A, Lewis P, Bouffet E, Bartels U, Zuccaro J, Agnihotri S, Ryall S, Barszczyk M, Chornenkyy Y, Bourgey M, Bourque G, Montpetit A, Cordero F, Castelo-Branco P, Mangerel J, Tabori U, Ho KC, Huang A, Taylor KR, Mackay A, Bendel AE, Nazarian J, Fangusaro JR, Karajannis MA, Zagzag D, Foreman NK, Donson A, Hegert JV, Smith A, Chan J, Lafay-Cousin L, Dunn S, Hukin J, Dunham C, Scheinemann K, Michaud J, Zelcer S, Ramsay D, Cain J, Brennan C, Souweidane MM, Jones C, Allis CD, Brudno M, Becher O, Hawkins C. Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations. Nat Genet. 2014 May; 46(5):451-6.
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Aschner Y, Khalifah AP, Briones N, Yamashita C, Dolgonos L, Young SK, Campbell MN, Riches DW, Redente EF, Janssen WJ, Henson PM, Sap J, Vacaresse N, Kapus A, McCulloch CA, Zemans RL, Downey GP. Protein tyrosine phosphatase a mediates profibrotic signaling in lung fibroblasts through TGF-? responsiveness. Am J Pathol. 2014 May; 184(5):1489-502.
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El-Gohary Y, Tulachan S, Wiersch J, Guo P, Welsh C, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G. A smad signaling network regulates islet cell proliferation. Diabetes. 2014 Jan; 63(1):224-36.
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Song K, Shankar E, Yang J, Bane KL, Wahdan-Alaswad R, Danielpour D. Critical role of a survivin/TGF-?/mTORC1 axis in IGF-I-mediated growth of prostate epithelial cells. PLoS One. 2013; 8(5):e61896.
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