 Transcription Factor DP1
"Transcription Factor DP1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcription factor that possesses DNA-binding and E2F-binding domains but lacks a transcriptional activation domain. It is a binding partner for E2F TRANSCRIPTION FACTORS and enhances the DNA binding and transactivation function of the DP-E2F complex.
| Descriptor ID |
D050680
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| MeSH Number(s) |
D12.776.930.908
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| Concept/Terms |
Transcription Factor DP1- Transcription Factor DP1
- DP1, Transcription Factor
- Dimerization Partner 1 Protein
- DP-1 Transcription Factor
- Transcription Factor, DP-1
- DP1 Protein
- E2F Dimerization Partner 1
- TFDP1 Protein
- Transcription Factor DP-1
- Factor DP-1, Transcription
- Transcription Factor DP 1
- Transcription Factor DRTF1
- DRTF1, Transcription Factor
- DRTF1 Transcription Factor
- Transcription Factor, DRTF1
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Below are MeSH descriptors whose meaning is more general than "Transcription Factor DP1".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factor DP1".
This graph shows the total number of publications written about "Transcription Factor DP1" by people in this website by year, and whether "Transcription Factor DP1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 5 | 5 | | 1997 | 0 | 5 | 5 | | 1998 | 0 | 4 | 4 | | 1999 | 0 | 2 | 2 | | 2000 | 0 | 2 | 2 | | 2018 | 1 | 0 | 1 | | 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factor DP1" by people in Profiles.
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Nakajima R, Deguchi R, Komori H, Zhao L, Zhou Y, Shirasawa M, Angelina A, Goto Y, Tohjo F, Nakahashi K, Nakata K, Iwanaga R, Bradford AP, Araki K, Warita T, Ohtani K. The TFDP1 gene coding for DP1, the heterodimeric partner of the transcription factor E2F, is a target of deregulated E2F. Biochem Biophys Res Commun. 2023 06 30; 663:154-162.
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Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford AP, Araki K, Ohtani K. Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes. Sci Rep. 2018 05 31; 8(1):8438.
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Smith DS, Leone G, DeGregori J, Ahmed MN, Qumsiyeh MB, Nevins JR. Induction of DNA replication in adult rat neurons by deregulation of the retinoblastoma/E2F G1 cell cycle pathway. Cell Growth Differ. 2000 Dec; 11(12):625-33.
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Knudsen KE, Booth D, Naderi S, Sever-Chroneos Z, Fribourg AF, Hunton IC, Feramisco JR, Wang JY, Knudsen ES. RB-dependent S-phase response to DNA damage. Mol Cell Biol. 2000 Oct; 20(20):7751-63.
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Zhu JW, DeRyckere D, Li FX, Wan YY, DeGregori J. A role for E2F1 in the induction of ARF, p53, and apoptosis during thymic negative selection. Cell Growth Differ. 1999 Dec; 10(12):829-38.
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Leone G, DeGregori J, Jakoi L, Cook JG, Nevins JR. Collaborative role of E2F transcriptional activity and G1 cyclindependent kinase activity in the induction of S phase. Proc Natl Acad Sci U S A. 1999 Jun 08; 96(12):6626-31.
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Knudsen ES, Buckmaster C, Chen TT, Feramisco JR, Wang JY. Inhibition of DNA synthesis by RB: effects on G1/S transition and S-phase progression. Genes Dev. 1998 Aug 01; 12(15):2278-92.
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Whitaker LL, Su H, Baskaran R, Knudsen ES, Wang JY. Growth suppression by an E2F-binding-defective retinoblastoma protein (RB): contribution from the RB C pocket. Mol Cell Biol. 1998 Jul; 18(7):4032-42.
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Yan Z, DeGregori J, Shohet R, Leone G, Stillman B, Nevins JR, Williams RS. Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. Proc Natl Acad Sci U S A. 1998 Mar 31; 95(7):3603-8.
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Kowalik TF, DeGregori J, Leone G, Jakoi L, Nevins JR. E2F1-specific induction of apoptosis and p53 accumulation, which is blocked by Mdm2. Cell Growth Differ. 1998 Feb; 9(2):113-8.
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