 Receptors, Aryl Hydrocarbon
"Receptors, Aryl Hydrocarbon" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that bind certain aryl hydrocarbons, translocate to the nucleus, and activate transcription of particular DNA segments. AH receptors are identified by their high-affinity binding to several carcinogenic or teratogenic environmental chemicals including polycyclic aromatic hydrocarbons found in cigarette smoke and smog, heterocyclic amines found in cooked foods, and halogenated hydrocarbons including dioxins and polychlorinated biphenyls. No endogenous ligand has been identified, but an unknown natural messenger with a role in cell differentiation and development is suspected.
| Descriptor ID |
D018336
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| MeSH Number(s) |
D12.776.260.643.715 D12.776.826.209.715 D12.776.930.760
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| Concept/Terms |
Receptors, Aryl Hydrocarbon- Receptors, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptor
- Receptor, Aryl Hydrocarbon
- Aryl Hydrocarbon Receptors
- Dioxin Receptor
- Receptor, Dioxin
- Dioxin Receptors
- Receptors, Dioxin
- Polyaromatic Hydrocarbon Receptors
- Polyaromatic Hydrocarbon Receptor
- Receptor, Polyaromatic Hydrocarbon
- Receptors, Polyaromatic Hydrocarbon
- TCDD Receptor
- Receptor, TCDD
- Receptors, TCDD
- TCDD Receptors
- AH Receptor
- Receptor, AH
- AH Receptors
- Receptors, AH
- Receptors, 2,3,7,8-Tetrachlorodibenzo-p-dioxin
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Below are MeSH descriptors whose meaning is more general than "Receptors, Aryl Hydrocarbon".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Aryl Hydrocarbon".
This graph shows the total number of publications written about "Receptors, Aryl Hydrocarbon" by people in this website by year, and whether "Receptors, Aryl Hydrocarbon" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1998 | 0 | 1 | 1 | | 2001 | 1 | 1 | 2 | | 2003 | 1 | 1 | 2 | | 2006 | 1 | 1 | 2 | | 2007 | 0 | 1 | 1 | | 2010 | 0 | 1 | 1 | | 2012 | 1 | 0 | 1 | | 2013 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 0 | 1 | | 2016 | 1 | 0 | 1 | | 2017 | 1 | 2 | 3 | | 2018 | 2 | 0 | 2 | | 2019 | 1 | 1 | 2 | | 2021 | 1 | 0 | 1 | | 2022 | 1 | 1 | 2 | | 2023 | 2 | 1 | 3 | | 2024 | 2 | 0 | 2 | | 2025 | 3 | 1 | 4 |
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Below are the most recent publications written about "Receptors, Aryl Hydrocarbon" by people in Profiles.
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Zhou X, Moreira S, Restelli C, Wang H, Jahangiri S, Aryal S, Tsao E, Zhang P, Niu M, Kumar H, Balde Z, Vujovic A, Liu L, Wong N, Arruda A, Minden MD, Zhou Y, Ravi B, Qi J, Li C, Hope KJ, Lu R. Activation of a nongenetic AHR-ELMSAN1 axis optimizes BET-targeting therapy and suppresses leukemia stem cells in preclinical models. Sci Transl Med. 2025 Aug 06; 17(810):eadn5400.
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Tsaktanis T, Ammon L, Lößlein L, Peter A, Vandrey O, Naumann UJ, Behne M, Cook LJ, Levy M, Yeaman MR, Bennett JL, Rothhammer V. Serum Levels of Aryl Hydrocarbon Receptor Plasma Agonist Activity Are Reduced in Patients With NMOSD and Correlate With Disease Activity. Neurol Neuroimmunol Neuroinflamm. 2025 09; 12(5):e200457.
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Sasse SK, Dahlin A, Sanford L, Gruca MA, Gupta A, Gally F, Wu AC, Iribarren C, Dowell RD, Weiss ST, Gerber AN. Enhancer RNA transcription pinpoints functional genetic variants linked to asthma. Nat Commun. 2025 Mar 31; 16(1):2750.
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Molina PA, Edell CJ, Dunaway LS, Kellum CE, Muir RQ, Jennings MS, Colson JC, De Miguel C, Rhoads MK, Buzzelli AA, Harrington LE, Meza-Perez S, Randall TD, Botta D, Müller DN, Pollock DM, Maynard CL, Pollock JS. Aryl Hydrocarbon Receptor Activation Promotes Effector CD4+ T Cell Homeostasis and Restrains Salt-Sensitive Hypertension. Function (Oxf). 2025 Mar 24; 6(2).
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Sugino KY, Janssen RC, McMahan RH, Zimmerman C, Friedman JE, Jonscher KR. Vertical Transfer of Maternal Gut Microbes to Offspring of Western Diet-Fed Dams Drives Reduced Levels of Tryptophan Metabolites and Postnatal Innate Immune Response. Nutrients. 2024 Jun 08; 16(12).
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Eichenfield LF, Silverberg JI, Hebert AA, Boguniewicz M. Targeting the aryl hydrocarbon receptor as a strategy to expand the therapeutic armamentarium in atopic dermatitis. J Dermatolog Treat. 2024 12; 35(1):2300354.
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Silverberg JI, Boguniewicz M, Quintana FJ, Clark RA, Gross L, Hirano I, Tallman AM, Brown PM, Fredericks D, Rubenstein DS, McHale KA. Tapinarof validates the aryl hydrocarbon receptor as a therapeutic target: A?clinical review. J Allergy Clin Immunol. 2024 Jul; 154(1):1-10.
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Hu XL, Xiao W, Lei Y, Green A, Lee X, Maradana MR, Gao Y, Xie X, Wang R, Chennell G, Basson MA, Kille P, Maret W, Bewick GA, Zhou Y, Hogstrand C. Aryl hydrocarbon receptor utilises cellular zinc signals to maintain the gut epithelial barrier. Nat Commun. 2023 09 05; 14(1):5431.
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Dolly A, P?tgens SA, Thibaut MM, Neyrinck AM, de Castro GS, Galbert C, Lefevre C, Wyart E, Gomes SP, Gon?alves DC, Lanthier N, Baldin P, Huot JR, Bonetto A, Seelaender M, Delzenne NM, Sokol H, Bindels LB. Impairment of aryl hydrocarbon receptor signalling promotes hepatic disorders in cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 06; 14(3):1569-1582.
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Wang WL, Kasamatsu J, Joshita S, Gilfillan S, Di Luccia B, Panda SK, Kim DH, Desai P, Bando JK, Huang SC, Yomogida K, Hoshino H, Fukushima M, Jacobsen EA, Van Dyken SJ, Ruedl C, Cella M, Colonna M. The aryl hydrocarbon receptor instructs the immunomodulatory profile of a subset of Clec4a4+ eosinophils unique to the small intestine. Proc Natl Acad Sci U S A. 2022 06 07; 119(23):e2204557119.
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