 Cyclic AMP Receptor Protein
"Cyclic AMP Receptor Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A transcriptional regulator in prokaryotes which, when activated by binding cyclic AMP, acts at several promoters. Cyclic AMP receptor protein was originally identified as a catabolite gene activator protein. It was subsequently shown to regulate several functions unrelated to catabolism, and to be both a negative and a positive regulator of transcription. Cell surface cyclic AMP receptors are not included (CYCLIC AMP RECEPTORS), nor are the eukaryotic cytoplasmic cyclic AMP receptor proteins, which are the regulatory subunits of CYCLIC AMP-DEPENDENT PROTEIN KINASES.
| Descriptor ID |
D002373
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| MeSH Number(s) |
D12.776.930.165
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| Concept/Terms |
Cyclic AMP Receptor Protein- Cyclic AMP Receptor Protein
- cAMP Receptor Proteins
- Proteins, cAMP Receptor
- Receptor Proteins, cAMP
- Catabolic Gene Activator
- Gene Activator, Catabolic
- Gene Activators, Catabolic
- Catabolic Gene Activators
- Cyclic AMP Receptor Proteins
- Activator Protein, Catabolite
- Activator Proteins, Catabolite
- Catabolite Activator Proteins
- Protein, Catabolite Activator
- Proteins, Catabolite Activator
- Catabolite Activator Protein
- Catabolite Gene Activator Protein
- Catabolite Gene Activator Proteins
- Catabolite Regulator Protein
- Catabolite Regulator Proteins
- Protein, Catabolite Regulator
- Proteins, Catabolite Regulator
- Regulator Protein, Catabolite
- Regulator Proteins, Catabolite
- cAMP Receptor Protein
- Protein, cAMP Receptor
- Receptor Protein, cAMP
- Activator, Catabolic Gene
- Activators, Catabolic Gene
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Below are MeSH descriptors whose meaning is more general than "Cyclic AMP Receptor Protein".
Below are MeSH descriptors whose meaning is more specific than "Cyclic AMP Receptor Protein".
This graph shows the total number of publications written about "Cyclic AMP Receptor Protein" by people in this website by year, and whether "Cyclic AMP Receptor Protein" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 | | 2020 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclic AMP Receptor Protein" by people in Profiles.
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McMackin EAW, Corley JM, Karash S, Marden J, Wolfgang MC, Yahr TL. Cautionary Notes on the Use of Arabinose- and Rhamnose-Inducible Expression Vectors in Pseudomonas aeruginosa. J Bacteriol. 2021 07 22; 203(16):e0022421.
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Lara-Gonzalez S, Dantas Machado AC, Rao S, Napoli AA, Birktoft J, Di Felice R, Rohs R, Lawson CL. The RNA Polymerase a Subunit Recognizes the DNA Shape of the Upstream Promoter Element. Biochemistry. 2020 12 08; 59(48):4523-4532.
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Janssen KH, Corley JM, Djapgne L, Cribbs JT, Voelker D, Slusher Z, Nordell R, Regulski EE, Kazmierczak BI, McMackin EW, Yahr TL. Hfq and sRNA 179 Inhibit Expression of the Pseudomonas aeruginosa cAMP-Vfr and Type III Secretion Regulons. mBio. 2020 06 16; 11(3).
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Jones AK, Fulcher NB, Balzer GJ, Urbanowski ML, Pritchett CL, Schurr MJ, Yahr TL, Wolfgang MC. Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling. J Bacteriol. 2010 Nov; 192(21):5709-17.
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Dong A, Malecki JM, Lee L, Carpenter JF, Lee JC. Ligand-induced conformational and structural dynamics changes in Escherichia coli cyclic AMP receptor protein. Biochemistry. 2002 May 28; 41(21):6660-7.
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Heasley LE, Azari J, Brunton LL. Export of cyclic AMP from avian red cells. Independence from major membrane transporters and specific inhibition by prostaglandin A. Mol Pharmacol. 1985 Jan; 27(1):60-5.
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Luthin GR, Tabakoff B. Activation of adenylate cyclase by alcohols requires the nucleotide-binding protein. J Pharmacol Exp Ther. 1984 Mar; 228(3):579-87.
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