Lipocalin-2
"Lipocalin-2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lipocalin of approximately 200 amino acids that functions as an iron transporter and is expressed by cells of BONE MARROW and many other cells with secretory functions. It is involved in APOPTOSIS and may function to limit pathogenic bacterial growth as part of the INNATE IMMUNE RESPONSE.
Descriptor ID |
D000071068
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MeSH Number(s) |
D12.776.124.050.475 D12.776.157.469.325 D12.776.624.664.700.123
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Concept/Terms |
Lipocalin-2- Lipocalin-2
- Lipocalin 2
- NGAL Protein
- Oncogene 24p3 Protein
- Siderocalin Protein
- Neutrophil Gelatinase-Associated Lipocalin
- Neutrophil Gelatinase Associated Lipocalin
- Lipocalin-2 Protein
- Lipocalin 2 Protein
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Below are MeSH descriptors whose meaning is more general than "Lipocalin-2".
Below are MeSH descriptors whose meaning is more specific than "Lipocalin-2".
This graph shows the total number of publications written about "Lipocalin-2" by people in this website by year, and whether "Lipocalin-2" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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2006 | 0 | 2 | 2 | 2009 | 0 | 1 | 1 | 2010 | 0 | 1 | 1 | 2011 | 0 | 5 | 5 | 2012 | 0 | 4 | 4 | 2013 | 0 | 5 | 5 | 2015 | 0 | 1 | 1 | 2016 | 0 | 3 | 3 | 2017 | 0 | 1 | 1 | 2018 | 0 | 3 | 3 | 2019 | 0 | 2 | 2 | 2020 | 2 | 2 | 4 | 2021 | 0 | 1 | 1 | 2022 | 0 | 3 | 3 | 2023 | 0 | 1 | 1 | 2024 | 3 | 3 | 6 |
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Below are the most recent publications written about "Lipocalin-2" by people in Profiles.
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Pettit KA, Melink KF, Alten JA, Goldstein SL, Ollberding N, SooHoo M, Sullivan E, Zang H, Stanski NL, Gist KM. Biomarker-based acute kidney injury sub-phenotypes refine risk assessment in children undergoing cardiac surgery. Pediatr Nephrol. 2025 Feb; 40(2):523-531.
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Li J, Simmons AJ, Hawkins CV, Chiron S, Ramirez-Solano MA, Tasneem N, Kaur H, Xu Y, Revetta F, Vega PN, Bao S, Cui C, Tyree RN, Raber LW, Conner AN, Pilat JM, Jacobse J, McNamara KM, Allaman MM, Raffa GA, Gobert AP, Asim M, Goettel JA, Choksi YA, Beaulieu DB, Dalal RL, Horst SN, Pabla BS, Huo Y, Landman BA, Roland JT, Scoville EA, Schwartz DA, Washington MK, Shyr Y, Wilson KT, Coburn LA, Lau KS, Liu Q. Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease. Nat Commun. 2024 Aug 22; 15(1):7204.
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Sullivan E, Melink K, Pettit K, Goldstein SL, Zang H, Ollberding NJ, SooHoo M, Alten JA, Stanski NL, Gist KM. Prediction of cardiac surgery associated acute kidney injury using response to loop diuretic and urine neutrophil gelatinase associated lipocalin. Pediatr Nephrol. 2024 Dec; 39(12):3597-3606.
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Wang W, You Z, Steele CN, Gitomer B, Chonchol M, Nowak KL. Changes in tubular biomarkers with dietary intervention and metformin in patients with autosomal dominant polycystic kidney disease: a post-hoc analysis of two clinical trials. BMC Nephrol. 2024 Jun 25; 25(1):206.
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Turner MJ, Rumpel JA, Spray BJ, Stence N, Neuberger I, Frymoyer A, Chock VY, Courtney S, Gist K. Urine biomarkers of acute kidney injury and association with brain MRI abnormalities in neonatal hypoxic-ischemic encephalopathy. J Perinatol. 2024 Aug; 44(8):1203-1207.
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Shiadeh SMJ, Goretta F, Svedin P, Jansson T, Mallard C, Ardalan M. Long-term impact of maternal obesity on the gliovascular unit and ephrin signaling in the hippocampus of adult offspring. J Neuroinflammation. 2024 Feb 02; 21(1):39.
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Okamura K, Lu S, He Z, Altmann C, Montford JR, Li AS, Lucia MS, Orlicky DJ, Weiser-Evans M, Faubel S. IL-6 mediates the hepatic acute phase response after prerenal azotemia in a clinically defined murine model. Am J Physiol Renal Physiol. 2023 09 01; 325(3):F328-F344.
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Ascher SB, Scherzer R, Estrella MM, Berry JD, de Lemos JA, Jotwani VK, Garimella PS, Malhotra R, Bullen AL, Katz R, Ambrosius WT, Cheung AK, Chonchol M, Killeen AA, Ix JH, Shlipak MG. Kidney tubule health, mineral metabolism and adverse events in persons with CKD in SPRINT. Nephrol Dial Transplant. 2022 08 22; 37(9):1637-1646.
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Johnson MJ, Tommerdahl KL, Vinovskis C, Waikar S, Reinicke T, Parikh CR, Obeid W, Nelson RG, van Raalte DH, Pyle L, Nadeau KJ, Bjornstad P. Relationship between biomarkers of tubular injury and intrarenal hemodynamic dysfunction in youth with type 1 diabetes. Pediatr Nephrol. 2022 12; 37(12):3085-3092.
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Barnett AM, Babcock MC, Watso JC, Migdal KU, Guti?rrez OM, Farquhar WB, Robinson AT. High dietary salt intake increases urinary NGAL excretion and creatinine clearance in healthy young adults. Am J Physiol Renal Physiol. 2022 04 01; 322(4):F392-F402.
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