 Mediator Complex Subunit 1
"Mediator Complex Subunit 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mediator complex subunit that is believed to play a key role in the coactivation of nuclear receptor-activated transcription by the mediator complex. It interacts with a variety of nuclear receptors including RETINOIC ACID RECEPTORS; THYROID HORMONE RECEPTORS; VITAMIN D RECEPTORS; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS; ESTROGEN RECEPTORS; and GLUCOCORTICOID RECEPTORS.
| Descriptor ID |
D056913
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| MeSH Number(s) |
D05.500.374.750 D12.644.360.024.309.750 D12.644.360.024.314.049 D12.776.157.057.072.750 D12.776.157.057.080.049 D12.776.476.024.388.750 D12.776.476.024.394.049 D12.776.660.551.750 D12.776.660.675.049 D12.776.930.617.049
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| Concept/Terms |
Mediator Complex Subunit 1- Mediator Complex Subunit 1
- TRAP220
- Mediator of RNA Polymerase II Transcription Subunit 1
- p53 Regulatory Protein RB18A
- RB18A
- Vitamin D Receptor-Interacting Protein Complex Component DRIP205
- Vitamin D Receptor Interacting Protein Complex Component DRIP205
- Peroxisome Proliferator-Activated Receptor Binding Protein
- Peroxisome Proliferator Activated Receptor Binding Protein
- PPAR-Binding Protein
- PPAR Binding Protein
- Thyroid Receptor Interacting Protein 2
- TR-Associated Protein P220
- TR Associated Protein P220
- TRIP2 (Thyroid Receptor Interacting Protein 2)
- DRIP205
- Thyroid Hormone Receptor Associated Protein 220
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Below are MeSH descriptors whose meaning is more general than "Mediator Complex Subunit 1".
Below are MeSH descriptors whose meaning is more specific than "Mediator Complex Subunit 1".
This graph shows the total number of publications written about "Mediator Complex Subunit 1" by people in this website by year, and whether "Mediator Complex Subunit 1" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2008 | 0 | 1 | 1 | | 2011 | 1 | 0 | 1 | | 2013 | 0 | 1 | 1 | | 2020 | 0 | 1 | 1 |
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Below are the most recent publications written about "Mediator Complex Subunit 1" by people in Profiles.
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Klein IA, Boija A, Afeyan LK, Hawken SW, Fan M, Dall'Agnese A, Oksuz O, Henninger JE, Shrinivas K, Sabari BR, Sagi I, Clark VE, Platt JM, Kar M, McCall PM, Zamudio AV, Manteiga JC, Coffey EL, Li CH, Hannett NM, Guo YE, Decker TM, Lee TI, Zhang T, Weng JK, Taatjes DJ, Chakraborty A, Sharp PA, Chang YT, Hyman AA, Gray NS, Young RA. Partitioning of cancer therapeutics in nuclear condensates. Science. 2020 06 19; 368(6497):1386-1392.
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Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM, Parkinson C, Chin SF, Kingsbury Z, Wong AS, Marass F, Humphray S, Hadfield J, Bentley D, Chin TM, Brenton JD, Caldas C, Rosenfeld N. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature. 2013 May 02; 497(7447):108-12.
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Knuesel MT, Taatjes DJ. Mediator and post-recruitment regulation of RNA polymerase II. Transcription. 2011 Jan-Feb; 2(1):28-31.
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Meyer KD, Donner AJ, Knuesel MT, York AG, Espinosa JM, Taatjes DJ. Cooperative activity of cdk8 and GCN5L within Mediator directs tandem phosphoacetylation of histone H3. EMBO J. 2008 May 21; 27(10):1447-57.
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