 5-Lipoxygenase-Activating Proteins
"5-Lipoxygenase-Activating Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Scaffolding proteins that play an important role in the localization and activation of 5-LIPOXYGENASE.
| Descriptor ID |
D058927
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| MeSH Number(s) |
D12.776.157.057.001 D12.776.476.024.034 D12.776.543.019
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| Concept/Terms |
5-Lipoxygenase-Activating Proteins- 5-Lipoxygenase-Activating Proteins
- 5 Lipoxygenase Activating Proteins
- Arachidonate 5-Lipoxygenase Activating Proteins
- Arachidonate 5 Lipoxygenase Activating Proteins
- Arachidonate 5-Lipoxygenase Activating Protein
- Arachidonate 5 Lipoxygenase Activating Protein
- 5-Lipoxygenase-Activating Protein
- 5 Lipoxygenase Activating Protein
- 5-LO-Activating Protein
- 5 LO Activating Protein
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Below are MeSH descriptors whose meaning is more general than "5-Lipoxygenase-Activating Proteins".
Below are MeSH descriptors whose meaning is more specific than "5-Lipoxygenase-Activating Proteins".
This graph shows the total number of publications written about "5-Lipoxygenase-Activating Proteins" by people in this website by year, and whether "5-Lipoxygenase-Activating Proteins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 | | 1998 | 0 | 1 | 1 | | 2014 | 1 | 0 | 1 | | 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "5-Lipoxygenase-Activating Proteins" by people in Profiles.
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Nunns GR, Stringham JR, Gamboni F, Moore EE, Fragoso M, Stettler GR, Silliman CC, Banerjee A. Trauma and hemorrhagic shock activate molecular association of 5-lipoxygenase and 5-lipoxygenase-Activating protein in lung tissue. J Surg Res. 2018 09; 229:262-270.
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Fang WF, Douglas IS, Wang CC, Kao HC, Chang YT, Tseng CC, Huang KT, Chang HC, Lin MC. 5-Lipoxygenase activating protein (FLAP) dependent leukotriene biosynthesis inhibition (MK591) attenuates Lipid A endotoxin-induced inflammation. PLoS One. 2014; 9(7):e102622.
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Hevko JM, Murphy RC. Formation of murine macrophage-derived 5-oxo-7-glutathionyl-8,11,14-eicosatrienoic acid (FOG7) is catalyzed by leukotriene C4 synthase. J Biol Chem. 2002 Mar 01; 277(9):7037-43.
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Wright L, Tuder RM, Wang J, Cool CD, Lepley RA, Voelkel NF. 5-Lipoxygenase and 5-lipoxygenase activating protein (FLAP) immunoreactivity in lungs from patients with primary pulmonary hypertension. Am J Respir Crit Care Med. 1998 Jan; 157(1):219-29.
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Henderson WR, Lewis DB, Albert RK, Zhang Y, Lamm WJ, Chiang GK, Jones F, Eriksen P, Tien YT, Jonas M, Chi EY. The importance of leukotrienes in airway inflammation in a mouse model of asthma. J Exp Med. 1996 Oct 01; 184(4):1483-94.
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Voelkel NF, Tuder RM, Wade K, H?per M, Lepley RA, Goulet JL, Koller BH, Fitzpatrick F. Inhibition of 5-lipoxygenase-activating protein (FLAP) reduces pulmonary vascular reactivity and pulmonary hypertension in hypoxic rats. J Clin Invest. 1996 Jun 01; 97(11):2491-8.
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