 MTOR Associated Protein, LST8 Homolog
"MTOR Associated Protein, LST8 Homolog" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An adaptor protein, consisting of seven WD REPEATS along its length, that functions as a component of the MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1 and MTORC2 COMPLEX. It interacts directly with MTOR to enhance its kinase activity and stabilizes the MTOR-RPTOR PROTEIN interaction in nutrient-poor conditions, favoring RPTOR inhibition of MTOR activity.
| Descriptor ID |
D000076242
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| MeSH Number(s) |
D05.500.337.250 D08.811.913.696.620.682.700.931.500.250 D12.644.360.024.310 D12.776.157.057.073 D12.776.476.024.389 D12.776.476.925.500.250
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "MTOR Associated Protein, LST8 Homolog".
- Chemicals and Drugs [D]
- Macromolecular Substances [D05]
- Multiprotein Complexes [D05.500]
- Mechanistic Target of Rapamycin Complex 1 [D05.500.337]
- MTOR Associated Protein, LST8 Homolog [D05.500.337.250]
- Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
- Transferases [D08.811.913]
- Phosphotransferases [D08.811.913.696]
- Phosphotransferases (Alcohol Group Acceptor) [D08.811.913.696.620]
- Protein Kinases [D08.811.913.696.620.682]
- Protein-Serine-Threonine Kinases [D08.811.913.696.620.682.700]
- TOR Serine-Threonine Kinases [D08.811.913.696.620.682.700.931]
- Mechanistic Target of Rapamycin Complex 1 [D08.811.913.696.620.682.700.931.500]
- MTOR Associated Protein, LST8 Homolog [D08.811.913.696.620.682.700.931.500.250]
- Amino Acids, Peptides, and Proteins [D12]
- Peptides [D12.644]
- Intracellular Signaling Peptides and Proteins [D12.644.360]
- Adaptor Proteins, Signal Transducing [D12.644.360.024]
- MTOR Associated Protein, LST8 Homolog [D12.644.360.024.310]
- Proteins [D12.776]
- Carrier Proteins [D12.776.157]
- Adaptor Proteins, Signal Transducing [D12.776.157.057]
- MTOR Associated Protein, LST8 Homolog [D12.776.157.057.073]
- Intracellular Signaling Peptides and Proteins [D12.776.476]
- Adaptor Proteins, Signal Transducing [D12.776.476.024]
- MTOR Associated Protein, LST8 Homolog [D12.776.476.024.389]
- TOR Serine-Threonine Kinases [D12.776.476.925]
- Mechanistic Target of Rapamycin Complex 1 [D12.776.476.925.500]
- MTOR Associated Protein, LST8 Homolog [D12.776.476.925.500.250]
Below are MeSH descriptors whose meaning is more specific than "MTOR Associated Protein, LST8 Homolog".
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