 Nuclear Receptor Coactivator 3
"Nuclear Receptor Coactivator 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nuclear receptor coactivator with specificity for ESTROGEN RECEPTORS and PROGESTERONE RECEPTORS. It contains a histone acetyltransferase activity that may play a role in CHROMATIN REMODELING during the process of nuclear receptor-induced transcription. The coactivator has been found at elevated levels in certain HORMONE-DEPENDENT NEOPLASMS such as those found in BREAST CANCER.
| Descriptor ID |
D056921
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| MeSH Number(s) |
D08.811.913.050.134.415.500.150 D12.644.360.024.314.300 D12.776.157.057.080.300 D12.776.476.024.394.300 D12.776.660.675.300 D12.776.930.617.300
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| Concept/Terms |
Nuclear Receptor Coactivator 3- Nuclear Receptor Coactivator 3
- Thyroid Hormone Receptor Activator Molecule 1
- Amplified in Breast Cancer-1 Protein
- Amplified in Breast Cancer 1 Protein
- Steroid Receptor Coactivator 3
- Nuclear Receptor Coactivator-3
- Receptor-Associated Coactivator 3
- Receptor Associated Coactivator 3
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Below are MeSH descriptors whose meaning is more general than "Nuclear Receptor Coactivator 3".
Below are MeSH descriptors whose meaning is more specific than "Nuclear Receptor Coactivator 3".
This graph shows the total number of publications written about "Nuclear Receptor Coactivator 3" by people in this website by year, and whether "Nuclear Receptor Coactivator 3" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 | | 2010 | 1 | 0 | 1 | | 2015 | 1 | 0 | 1 | | 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Nuclear Receptor Coactivator 3" by people in Profiles.
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Hickey TE, Selth LA, Chia KM, Laven-Law G, Milioli HH, Roden D, Jindal S, Hui M, Finlay-Schultz J, Ebrahimie E, Birrell SN, Stelloo S, Iggo R, Alexandrou S, Caldon CE, Abdel-Fatah TM, Ellis IO, Zwart W, Palmieri C, Sartorius CA, Swarbrick A, Lim E, Carroll JS, Tilley WD. The androgen receptor is a tumor suppressor in estrogen receptor-positive breast cancer. Nat Med. 2021 02; 27(2):310-320.
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Fant CB, Taatjes DJ. All in the family: a portrait of a nuclear receptor co-activator complex. Mol Cell. 2015 Mar 19; 57(6):952-954.
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Wargon V, Riggio M, Giulianelli S, Sequeira GR, Rojas P, May M, Polo ML, Gorostiaga MA, Jacobsen B, Molinolo A, Novaro V, Lanari C. Progestin and antiprogestin responsiveness in breast cancer is driven by the PRA/PRB ratio via AIB1 or SMRT recruitment to the CCND1 and MYC promoters. Int J Cancer. 2015 Jun 01; 136(11):2680-92.
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Axlund SD, Lambert JR, Nordeen SK. HOXC8 inhibits androgen receptor signaling in human prostate cancer cells by inhibiting SRC-3 recruitment to direct androgen target genes. Mol Cancer Res. 2010 Dec; 8(12):1643-55.
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Balmer NN, Richer JK, Spoelstra NS, Torkko KC, Lyle PL, Singh M. Steroid receptor coactivator AIB1 in endometrial carcinoma, hyperplasia and normal endometrium: Correlation with clinicopathologic parameters and biomarkers. Mod Pathol. 2006 Dec; 19(12):1593-605.
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