Serpins
"Serpins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of serine proteinase inhibitors which are similar in amino acid sequence and mechanism of inhibition, but differ in their specificity toward proteolytic enzymes. Some members of the serpin family may be substrates rather than inhibitors of SERINE ENDOPEPTIDASES.
Descriptor ID |
D015843
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MeSH Number(s) |
D12.644.861 D12.776.872 D27.505.519.389.745.800.675
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Concept/Terms |
Serpins- Serpins
- Serpin Protease Inhibitors
- Inhibitors, Serpin Protease
- Protease Inhibitors, Serpin
- Serpin Peptidase Inhibitors
- Inhibitors, Serpin Peptidase
- Peptidase Inhibitors, Serpin
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Below are MeSH descriptors whose meaning is more general than "Serpins".
Below are MeSH descriptors whose meaning is more specific than "Serpins".
This graph shows the total number of publications written about "Serpins" by people in this website by year, and whether "Serpins" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
Year | Major Topic | Minor Topic | Total |
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1999 | 0 | 1 | 1 | 2004 | 1 | 1 | 2 | 2009 | 0 | 1 | 1 | 2010 | 2 | 1 | 3 | 2012 | 0 | 1 | 1 | 2013 | 1 | 0 | 1 | 2014 | 1 | 0 | 1 | 2015 | 0 | 2 | 2 | 2022 | 2 | 0 | 2 |
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Below are the most recent publications written about "Serpins" by people in Profiles.
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Chuang TP, Lai WY, Gabre JL, Lind DE, Umapathy G, Bokhari AA, Bergman B, Kristenson L, Thor?n FB, Le A, Doebele RC, Van den Eynden J, Palmer RH, Hallberg B. ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. Proc Natl Acad Sci U S A. 2023 02 21; 120(8):e2216479120.
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Schaid TR, LaCroix I, Hansen KC, D'Alessandro A, Moore EE, Sauaia A, Dzieciatkowska M, DeBot M, Cralley AL, Thielen O, Hallas W, Erickson C, Mitra S, Banerjee A, Jones K, Silliman CC, Cohen MJ. A proteomic analysis of NETosis in trauma: Emergence of serpinB1 as a key player. J Trauma Acute Care Surg. 2023 03 01; 94(3):361-370.
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de Graaf DM, Teufel LU, de Nooijer AH, van Gammeren AJ, Ermens AAM, Ga?l IO, Cri?an TO, van de Veerdonk FL, Netea MG, Dinarello CA, Joosten LAB, Arts RJW. Exploratory analysis of interleukin-38 in hospitalized COVID-19 patients. Immun Inflamm Dis. 2022 11; 10(11):e712.
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Steele MP, Luna LG, Coldren CD, Murphy E, Hennessy CE, Heinz D, Evans CM, Groshong S, Cool C, Cosgrove GP, Brown KK, Fingerlin TE, Schwarz MI, Schwartz DA, Yang IV. Relationship between gene expression and lung function in Idiopathic Interstitial Pneumonias. BMC Genomics. 2015 Oct 26; 16:869.
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Cho MH, Castaldi PJ, Hersh CP, Hobbs BD, Barr RG, Tal-Singer R, Bakke P, Gulsvik A, San Jos? Est?par R, Van Beek EJ, Coxson HO, Lynch DA, Washko GR, Laird NM, Crapo JD, Beaty TH, Silverman EK. A Genome-Wide Association Study of Emphysema and Airway Quantitative Imaging Phenotypes. Am J Respir Crit Care Med. 2015 Sep 01; 192(5):559-69.
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Olivieri O, Cecconi D, Castagna A, Chiecchi L, Guarini P, Gunasekaran M, Morandini F, Brazzarola P, Zolla L, D'Alessandro A, Veglio F, Mulatero P, Pizzolo F. Urinary protease inhibitor Serpin B3 is higher in women and is further increased in female patients affected by aldosterone producing adenoma. Mol Biosyst. 2014 Jun; 10(6):1281-9.
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Heit C, Jackson BC, McAndrews M, Wright MW, Thompson DC, Silverman GA, Nebert DW, Vasiliou V. Update of the human and mouse SERPIN gene superfamily. Hum Genomics. 2013 Oct 30; 7:22.
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Ashton JM, Balys M, Neering SJ, Hassane DC, Cowley G, Root DE, Miller PG, Ebert BL, McMurray HR, Land H, Jordan CT. Gene sets identified with oncogene cooperativity analysis regulate in vivo growth and survival of leukemia stem cells. Cell Stem Cell. 2012 Sep 07; 11(3):359-72.
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Olsen JR, Dehdashti F, Siegel BA, Zighelboim I, Grigsby PW, Schwarz JK. Prognostic utility of squamous cell carcinoma antigen in carcinoma of the cervix: association with pre- and posttreatment FDG-PET. Int J Radiat Oncol Biol Phys. 2011 Nov 01; 81(3):772-7.
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Erickson JA, Lu J, Smith JJ, Bornhorst JA, Grenache DG, Ashwood ER. Immunoassay for quantifying squamous cell carcinoma antigen in serum. Clin Chem. 2010 Sep; 56(9):1496-9.
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